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Heinrich-Heine-Universität Düsseldorf: Düsseldorf, NRW, DE

1997-08 to present (Institute of Human Genetics)
Employment
Source: Self-asserted source
Manfred Beier

Works (28)

Gene expression studies of WT1 mutant Wilms tumor cell lines in the frame work of published kidney development data reveals their early kidney stem cell origin.

PloS one
2023-01-23 | Journal article
DOI: 10.1371/journal.pone.0270380
PMID: 36689432
PMC: PMC9870146
Contributors: Brigitte Royer-Pokora; Wruck W; Adjaye J; Beier M
Source: Self-asserted source
Manfred Beier

ADAM10 and ADAM17-Novel Players in Retinoblastoma Carcinogenesis.

International journal of molecular sciences
2022-10-20 | Journal article
DOI: 10.3390/ijms232012621
PMID: 36293469
Contributors: Manfred Beier; Dario Van Meenen; Doege A; Alefeld E; André Haase; Beier M; Kiefer T; Biewald E; Metz K; Dräger O et al.
Source: Self-asserted source
Manfred Beier

TFF1 in Aqueous Humor-A Potential New Biomarker for Retinoblastoma.

Cancers
2022-01-28 | Journal article
DOI: 10.3390/cancers14030677
PMID: 35158945
PMC: PMC8833755
Source: Self-asserted source
Manfred Beier

Genetic analysis of single disseminated tumor cells in the lymph nodes and bone marrow of patients with head and neck squamous cell carcinoma

Molecular Oncology
2021-10-31 | Journal article
DOI: 10.1002/1878-0261.13113
Part of ISSN: 1574-7891
Part of ISSN: 1878-0261
Source: Self-asserted source
Manfred Beier

Comprehensive Biology and Genetics Compendium of Wilms Tumor Cell Lines with Different <i>WT1</i> Mutations.

Cancers
2020-12-28 | Journal article
DOI: 10.3390/cancers13010060
PMID: 33379206
PMC: PMC7801943
Source: Self-asserted source
Manfred Beier
grade
Preferred source (of 3)‎

Distinctive mutational spectrum and karyotype disruption in long-term cisplatin-treated urothelial carcinoma cell lines.

Scientific reports
2019-10-09 | Journal article
DOI: 10.1038/s41598-019-50891-w
PMID: 31597922
PMC: PMC6785536
Source: Self-asserted source
Manfred Beier

Neue Ansätze in Diagnostik und Therapie uroonkologischer Erkrankungen

Der Urologe
2019-02 | Journal article
DOI: 10.1007/s00120-019-0863-z
Part of ISSN: 0340-2592
Part of ISSN: 1433-0563
Source: Self-asserted source
Manfred Beier

TREFOIL FACTOR FAMILY 1 EXPRESSION CORRELATES WITH CLINICAL OUTCOME IN PATIENTS WITH RETINOBLASTOMA.

Retina (Philadelphia, Pa.)
2018-12-01 | Journal article
DOI: 10.1097/iae.0000000000001881
PMID: 29016460
Contributors: Maike Anna Busch; Metz K; Beier M; Biewald E; Nicole Dünker
Source: Self-asserted source
Manfred Beier

Chemotherapy and terminal skeletal muscle differentiation in WT1-mutant Wilms tumors.

Cancer medicine
2018-03-15 | Journal article
DOI: 10.1002/cam4.1379
PMID: 29542868
PMC: PMC5911586
Source: Self-asserted source
Manfred Beier

Array comparative genomic hybridization of 18 pancreatic ductal adenocarcinomas and their autologous metastases.

BMC research notes
2017-11-06 | Journal article
DOI: 10.1186/s13104-017-2886-0
PMID: 29110683
PMC: PMC5674747
Source: Self-asserted source
Manfred Beier

Reduction of the tumorigenic potential of human retinoblastoma cell lines by TFF1 overexpression involves p53/caspase signaling and miR-18a regulation.

International journal of cancer
2017-05-19 | Journal article
DOI: 10.1002/ijc.30768
PMID: 28481041
Source: Self-asserted source
Manfred Beier

Bioinformatic Evaluation and Comparison of Parallel aSNP and aCGH Analyses of Myelodysplastic Syndromes Patients with Normal Karyotype

Clinics in Oncology
2016-10-19 | Journal article
Contributors: Manfred Beier; Sabrina Claßen-von Spee; Mar Mallo; Simone de Leve; Leonor Arenillas; Carmen Pedro; Francesc Solé; Brigitte Royer-Pokora
Source: Self-asserted source
Manfred Beier

Establishment of a Conditionally Immortalized Wilms Tumor Cell Line with a Homozygous WT1 Deletion within a Heterozygous 11p13 Deletion and UPD Limited to 11p15.

PloS one
2016-05-23 | Journal article
DOI: 10.1371/journal.pone.0155561
PMID: 27213811
PMC: PMC4876997
Source: Self-asserted source
Manfred Beier

Classification of a frameshift/extended and a stop mutation in WT1 as gain-of-function mutations that activate cell cycle genes and promote Wilms tumour cell proliferation.

Human molecular genetics
2014-03-11 | Journal article
DOI: 10.1093/hmg/ddu111
PMID: 24619359
PMC: PMC4082364
Source: Self-asserted source
Manfred Beier

A novel inverted 17p13.3 microduplication disrupting PAFAH1B1 (LIS1) in a girl with syndromic lissencephaly.

American journal of medical genetics. Part A
2013-04-30 | Journal article
DOI: 10.1002/ajmg.a.35904
PMID: 23633430
Source: Self-asserted source
Manfred Beier

Evaluation of chromosome 11p imbalances in aniridia and Wilms tumor patients.

American journal of medical genetics. Part A
2013-03-13 | Journal article
DOI: 10.1002/ajmg.a.35818
PMID: 23494989
Source: Self-asserted source
Manfred Beier

Overcoming chemotherapy resistance of ovarian cancer cells by liposomal cisplatin: molecular mechanisms unveiled by gene expression profiling.

Biochemical pharmacology
2013-02-08 | Journal article
DOI: 10.1016/j.bcp.2013.01.028
PMID: 23396090
Source: Self-asserted source
Manfred Beier

"Xenopus paratropicalis" is not a valid name

Zootaxa
2011-09-20 | Journal article
DOI: 10.11646/zootaxa.3035.1.2
Part of ISSN: 1175-5334
Part of ISSN: 1175-5326
Source: Self-asserted source
Manfred Beier

Comprehensive array CGH of normal karyotype myelodysplastic syndromes reveals hidden recurrent and individual genomic copy number alterations with prognostic relevance.

Leukemia
2011-01-28 | Journal article
DOI: 10.1038/leu.2010.293
PMID: 21274003
Source: Self-asserted source
Manfred Beier

Wilms tumor cells with WT1 mutations have characteristic features of mesenchymal stem cells and express molecular markers of paraxial mesoderm.

Human molecular genetics
2010-01-27 | Journal article
DOI: 10.1093/hmg/ddq042
PMID: 20106868
Source: Self-asserted source
Manfred Beier

Hyperactivation of the insulin-like growth factor receptor I signaling pathway is an essential event for cisplatin resistance of ovarian cancer cells.

Cancer research
2009-03-24 | Journal article
DOI: 10.1158/0008-5472.can-08-3153
PMID: 19318572
Source: Self-asserted source
Manfred Beier

Clinical relevance of mutations in the Wilms tumor suppressor 1 gene WT1 and the cadherin-associated protein beta1 gene CTNNB1 for patients with Wilms tumors: results of long-term surveillance of 71 patients from International Society of Pediatric Oncology Study 9/Society for Pediatric Oncology.

Cancer
2008-09-01 | Journal article
DOI: 10.1002/cncr.23672
PMID: 18618575
Source: Self-asserted source
Manfred Beier

Molecular definition of chromosome arm 5q deletion end points and detection of hidden aberrations in patients with myelodysplastic syndromes and isolated del(5q) using oligonucleotide array CGH.

Genes, chromosomes & cancer
2007-12-01 | Journal article
DOI: 10.1002/gcc.20498
PMID: 17823930
Source: Self-asserted source
Manfred Beier

Hymenochirus curtipes: Geographic distribution

Herpetological Review
2006 | Journal article
Contributors: Manfred Beier; Kate Jackson
Source: Self-asserted source
Manfred Beier

Delineation by molecular cytogenetics of 5q deletion breakpoints in myelodyplastic syndromes and acute myeloid leukemia.

Cancer genetics and cytogenetics
2006-05-01 | Journal article
DOI: 10.1016/j.cancergencyto.2005.08.003
PMID: 16682289
Source: Self-asserted source
Manfred Beier

Molecular cytogenetic profiling of complex karyotypes in primary myelodysplastic syndromes and acute myeloid leukemia.

Cancer genetics and cytogenetics
2006-02-01 | Journal article
DOI: 10.1016/j.cancergencyto.2005.09.007
PMID: 16490597
Source: Self-asserted source
Manfred Beier

An algorithm and tool for computing exact conditional probabilities of configuration frequencies.

Psychology Science
2005 | Journal article
Source: Self-asserted source
Manfred Beier

Twenty-four new cases of WT1 germline mutations and review of the literature: genotype/phenotype correlations for Wilms tumor development.

American journal of medical genetics. Part A
2004-06-01 | Journal article
DOI: 10.1002/ajmg.a.30015
PMID: 15150775
Source: Self-asserted source
Manfred Beier
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