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Singapore

Activities

Employment (4)

Institute of Molecular and Cell Biology: Singapore, SG

2022 to present | Principal Investigator
Employment
Source: Self-asserted source
Shigeki Sugii

Duke-NUS Medical School: Singapore, SG

2011 to present (Cardiovascular and Metabolic Disorders Program)
Employment
Source: Self-asserted source
Shigeki Sugii

Institute of Bioengineering and Bioimaging, A*STAR: Singapore, SG

2019 to 2021 | Group Leader
Employment
Source: Self-asserted source
Shigeki Sugii

Singapore Bioimaging Consortium, A*STAR: Singapore, SG

2011 to 2019 | Group Leader (Fat Metabolism and Stem Cell Group)
Employment
Source: Self-asserted source
Shigeki Sugii

Education and qualifications (3)

Salk Institute for Biological Studies: La Jolla, CA, US

2003 to 2010 | Postdoctoral Research
Education
Source: Self-asserted source
Shigeki Sugii

Dartmouth College Geisel School of Medicine: Hanover, NH, US

1997 to 2003 | Ph.D.
Education
Source: Self-asserted source
Shigeki Sugii

Kyoto University: Kyoto, JP

1992 to 1996 | B.S.
Education
Source: Self-asserted source
Shigeki Sugii

Works (50 of 89)

Items per page:
Page 1 of 2

Alternative fat: redefining adipocytes for biomanufacturing cultivated meat

Trends in Biotechnology
2023-05 | Journal article
Contributors: Shigeki Sugii; Cheryl Yeh Qi Wong; Angela Khin Oo Lwin; Lamony Jian Ming Chew
Source: check_circle
Crossref

Reassessment of adipocyte technology for cellular agriculture of alternative fat

Comprehensive Reviews in Food Science and Food Safety
2022-09 | Journal article
Contributors: Shigeki Sugii; Cheryl Yeh Qi Wong; Angela Khin Oo Lwin; Lamony Jian Ming Chew
Source: check_circle
Crossref

CD10 marks non-canonical PPARγ-independent adipocyte maturation and browning potential of adipose-derived stem cells

Stem Cell Research & Therapy
2021-12 | Journal article
Contributors: Smarajit Chakraborty; Wee Kiat Ong; Winifred W. Y. Yau; Zhihong Zhou; K. N. Bhanu Prakash; Sue-Anne Toh; Weiping Han; Paul M. Yen; Shigeki Sugii
Source: check_circle
Crossref

Adipose Tissue: Understanding the Heterogeneity of Stem Cells for Regenerative Medicine.

Biomolecules
2021-06 | Journal article
Contributors: Ong WK; Chakraborty S; Sugii S
Source: Self-asserted source
Shigeki Sugii via Europe PubMed Central

Novel live cell fluorescent probe for human-induced pluripotent stem cells highlights early reprogramming population.

Stem cell research & therapy
2021-02 | Journal article
Contributors: Sriram S; Kang NY; Subramanian S; Nandi T; Sudhagar S; Xing Q; Tong GJ; Chen AK; Srijaya TC; Tan P et al.
Source: Self-asserted source
Shigeki Sugii via Europe PubMed Central

Diversification of reprogramming trajectories revealed by parallel single-cell transcriptome and chromatin accessibility sequencing

Science Advances
2020-09-11 | Journal article
Contributors: Q. R. Xing; C. A. El Farran; P. Gautam; Y. S. Chuah; T. Warrier; C. X. D. Toh; N. Y. Kang; S. Sugii; Y. T. Chang; J. Xu et al.
Source: check_circle
Crossref
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Trxlp, a thioredoxin-like effector from Edwardsiella piscicida inhibits cellular redox signaling and nuclear translocation of NF-κB.

International journal of biological macromolecules
2020-01 | Journal article
Contributors: Sayed A; Chakraborty S; Leung KY; Sugii S; Mok YK
Source: Self-asserted source
Shigeki Sugii via Europe PubMed Central
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Preferred source (of 2)‎

MSCs as Biological Drugs

A Roadmap to Non-Hematopoietic Stem Cell-based Therapeutics
2019 | Other
Part of ISBN: 9780128119204
Contributors: Thekkeparambil Chandrabose Srijaya; Sandhya Sriram; Noor Hayaty Abu Kasim; Shigeki Sugii
Source: Self-asserted source
Shigeki Sugii via Crossref Metadata Search

Fast Adipogenesis Tracking System (FATS)—a robust, high-throughput, automation-ready adipogenesis quantification technique

Stem Cell Research & Therapy
2019-12 | Journal article
Contributors: Chengxiang Yuan; Smarajit Chakraborty; Krishna Kanth Chitta; Subha Subramanian; Tau En Lim; Weiping Han; K. N. Bhanu Prakash; Shigeki Sugii
Source: check_circle
Crossref
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Oxidative stress mediates depot-specific functional differences of human adipose-derived stem cells

Stem Cell Research & Therapy
2019-12 | Journal article
Contributors: Sandhya Sriram; Chengxiang Yuan; Smarajit Chakraborty; Winson Tay; Min Park; Asim Shabbir; Sue-Anne Toh; Weiping Han; Shigeki Sugii
Source: check_circle
Crossref
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MSCs as biological drugs

A Roadmap to Nonhematopoietic Stem Cell-Based Therapeutics: From the Bench to the Clinic
2018 | Book chapter
EID:

2-s2.0-85084608521

Contributors: Srijaya, T.C.; Sriram, S.; Kasim, N.H.A.; Sugii, S.
Source: Self-asserted source
Shigeki Sugii via Scopus - Elsevier

Recellularization of decellularized adipose tissue-derived stem cells: Role of the cell-secreted extracellular matrix in cellular differentiation

Biomaterials Science
2018 | Journal article
EID:

2-s2.0-85038967772

Part of ISSN: 20474849 20474830
Contributors: Guneta, V.; Zhou, Z.; Tan, N.S.; Sugii, S.; Wong, M.T.C.; Choong, C.
Source: Self-asserted source
Shigeki Sugii via Scopus - Elsevier

Thyroid hormone (T3) stimulates brown adipose tissue activation via mitochondrial biogenesis and MTOR-mediated mitophagy

Autophagy
2018-09 | Journal article
Part of ISSN: 1554-8627
Contributors: Winifred W. Yau; Brijesh K. Singh; Ronny Lesmana; Jin Zhou; Rohit A. Sinha; Kiraely A. Wong; Yajun Wu; Boon-Huat Bay; Shigeki Sugii; Lei Sun et al.
Source: Self-asserted source
Shigeki Sugii via Crossref Metadata Search
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A roundtable on responsible innovation with autologous stem cells in Australia, Japan and Singapore

Cytotherapy
2018-08 | Journal article
Part of ISSN: 1465-3249
Contributors: TAMRA LYSAGHT; MEGAN MUNSIE; ADAM CASTRICUM; JAMES H.P. HUI; KYOSHI OKADA; YOJI SATO; YOSHIKI SAWA; CAMERON STEWART; LIP KUN TAN; LYNN H.Y. TAN et al.
Source: Self-asserted source
Shigeki Sugii via Crossref Metadata Search
grade
Preferred source (of 2)‎

Quantitative in vivo detection of adipose tissue browning using diffuse reflectance spectroscopy in near-infrared II window

Journal of Biophotonics
2018-08 | Journal article
Part of ISSN: 1864-063X
Contributors: Kapil Dev; U. S Dinish; Smarajit Chakraborty; Renzhe Bi; Stefan Andersson-Engels; Shigeki Sugii; Malini Olivo
Source: Self-asserted source
Shigeki Sugii via Crossref Metadata Search
grade
Preferred source (of 2)‎

Multimodal imaging approach to monitor browning of adipose tissue in vivo

Journal of Lipid Research
2018-04 | Journal article
Part of ISSN: 0022-2275
Contributors: Xin Hui Derryn Chan; Ghayathri Balasundaram; Amalina Binte Ebrahim Attia; Julian L. Goggi; Boominathan Ramasamy; Weiping Han; Malini Olivo; Shigeki Sugii
Source: Self-asserted source
Shigeki Sugii via Crossref Metadata Search
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Amenable epigenetic traits of dental pulp stem cells underlie high capability of xeno-free episomal reprogramming

Stem Cell Research & Therapy
2018-03 | Journal article
Part of ISSN: 1757-6512
Contributors: Srijaya Thekkeparambil Chandrabose; Sandhya Sriram; Subha Subramanian; Shanshan Cheng; Wee Kiat Ong; Steve Rozen; Noor Hayaty Abu Kasim; Shigeki Sugii
Source: Self-asserted source
Shigeki Sugii via Crossref Metadata Search
grade
Preferred source (of 3)‎

Diffuse Optical Spectroscopy and Imaging to Detect and Quantify Adipose Tissue Browning

Scientific Reports
2017 | Journal article
EID:

2-s2.0-85011306599

Part of ISSN: 20452322
Contributors: Dinish, U.S.; Wong, C.L.; Sriram, S.; Ong, W.K.; Balasundaram, G.; Sugii, S.; Olivo, M.
Source: Self-asserted source
Shigeki Sugii via Scopus - Elsevier

Diffuse Optical Spectroscopy and Imaging to Detect and Quantify Adipose Tissue Browning

Scientific Reports
2017 | Journal article
Source: Self-asserted source
Shigeki Sugii

MIR-524-5p of the primate-specific C19MC miRNA cluster targets TP53IPN1-and EMT-Associated genes to regulate cellular reprogramming

Stem Cell Research and Therapy
2017 | Journal article
EID:

2-s2.0-85030182314

Part of ISSN: 17576512
Contributors: Nguyen, P.N.N.; Choo, K.B.; Huang, C.-J.; Sugii, S.; Cheong, S.K.; Kamarul, T.
Source: Self-asserted source
Shigeki Sugii via Scopus - Elsevier

Selective activation of miRNAs of the primate-specific chromosome 19 miRNA cluster (C19MC) in cancer and stem cells and possible contribution to regulation of apoptosis

Journal of Biomedical Science
2017 | Journal article
EID:

2-s2.0-85014658067

Part of ISSN: 14230127 10217770
Contributors: Nguyen, P.N.N.; Huang, C.-J.; Sugii, S.; Cheong, S.K.; Choo, K.B.
Source: Self-asserted source
Shigeki Sugii via Scopus - Elsevier

Selective activation of miRNAs of the primate-specific chromosome 19 miRNA cluster (C19MC) in cancer and stem cells and possible contribution to regulation of apoptosis

Journal of Biomedical Science
2017 | Journal article
Source: Self-asserted source
Shigeki Sugii

miR-524-5p of the primate-specific C19MC miRNA cluster targets TP53IPN1- and EMT-associated genes to regulate cellular reprogramming

Stem Cell Res Ther
2017-09 | Journal article
Source: Self-asserted source
Shigeki Sugii

A role for ceramides, but not sphingomyelins, as antagonists of insulin signaling and mitochondrial metabolism in C2C12 myotubes

Journal of Biological Chemistry
2016 | Journal article
EID:

2-s2.0-84994491935

Part of ISSN: 1083351X 00219258
Contributors: Park, M.; Kaddai, V.; Ching, J.; Fridianto, K.T.; Sieli, R.J.; Sugii, S.; Summers, S.A.
Source: Self-asserted source
Shigeki Sugii via Scopus - Elsevier

A Role for Ceramides, but NOT Sphingomyelins, as antagonists of insulin signaling and mitochondrial metabolism in C2C12 myotubes

Journal of Biological Chemistry
2016 | Journal article
Source: Self-asserted source
Shigeki Sugii

Adipocyte Ceramides Regulate Subcutaneous Adipose Browning, Inflammation, and Metabolism

Cell Metabolism
2016 | Journal article
EID:

2-s2.0-85003837216

Part of ISSN: 19327420 15504131
Contributors: Chaurasia, B.; Kaddai, V.A.; Lancaster, G.I.; Henstridge, D.C.; Sriram, S.; Galam, D.L.A.; Gopalan, V.; Prakash, K.N.B.; Velan, S.S.; Bulchand, S. et al.
Source: Self-asserted source
Shigeki Sugii via Scopus - Elsevier

Adipocyte Ceramides Regulate Subcutaneous Adipose Browning, Inflammation, and Metabolism

Cell Metabolism
2016 | Journal article
Source: Self-asserted source
Shigeki Sugii

Comparative study of adipose-derived stem cells from abdomen and breast

Annals of Plastic Surgery
2016 | Journal article
EID:

2-s2.0-84964583053

Part of ISSN: 15363708 01487043
Contributors: Guneta, V.; Tan, N.S.; Sugii, S.; Lim, T.C.; Wong, T.C.M.; Choong, C.
Source: Self-asserted source
Shigeki Sugii via Scopus - Elsevier

Comparative study of adipose-derived stem cells from abdomen and breast

Annals of plastic surgery
2016 | Journal article
Source: Self-asserted source
Shigeki Sugii

Retinoic acid is abundantly detected in different depots of adipose tissue by SERS

Adipocyte
2016 | Journal article
EID:

2-s2.0-85061447652

Part of ISSN: 2162397X 21623945
Contributors: Perumal, J.; Sriram, S.; Lim, H.Q.; Olivo, M.; Sugii, S.
Source: Self-asserted source
Shigeki Sugii via Scopus - Elsevier

Retinoic acid is abundantly detected in different depots of adipose tissue by SERS

Adipocyte
2016 | Journal article
Source: Self-asserted source
Shigeki Sugii

Retinoic acid mediates visceral-specific adipogenic defects of human adipose-derived stem cells

Diabetes
2016 | Journal article
EID:

2-s2.0-84964577835

Part of ISSN: 1939327X 00121797
Contributors: Takeda, K.; Sriram, S.; Chan, X.H.D.; Ong, W.K.; Yeo, C.R.; Tan, B.; Lee, S.-A.; Kong, K.V.; Hoon, S.; Jiang, H. et al.
Source: Self-asserted source
Shigeki Sugii via Scopus - Elsevier

Retinoic Acid Mediates Visceral-Specific Adipogenic Defects of Human Adipose-Derived Stem Cells

Diabetes
2016 | Journal article
Source: Self-asserted source
Shigeki Sugii

Segmentation and characterization of interscapular brown adipose tissue in rats by multi-parametric magnetic resonance imaging

Magnetic Resonance Materials in Physics, Biology and Medicine
2016 | Journal article
EID:

2-s2.0-84953394745

Part of ISSN: 13528661 09685243
Contributors: Bhanu Prakash, K.N.; Verma, S.K.; Yaligar, J.; Goggi, J.; Gopalan, V.; Lee, S.S.; Tian, X.; Sugii, S.; Leow, M.K.S.; Bhakoo, K. et al.
Source: Self-asserted source
Shigeki Sugii via Scopus - Elsevier

Segmentation and characterization of interscapular brown adipose tissue in rats by multi-parametric magnetic resonance imaging

Magnetic Resonance Materials in Physics, Biology and Medicine
2016 | Journal article
Source: Self-asserted source
Shigeki Sugii

Stem Cells in Dentistry: Potential Applications and Perspectives in Clinical Research

Bone and Cartilage Regeneration
2016 | Book chapter
Source: Self-asserted source
Shigeki Sugii

Uncertain Oversight of Regenerative Medicines in Japan under the ASRM

Cell Stem Cell
2016 | Journal article
EID:

2-s2.0-84962853128

Part of ISSN: 18759777 19345909
Contributors: Lysaght, T.; Sugii, S.
Source: Self-asserted source
Shigeki Sugii via Scopus - Elsevier

Uncertain Oversight of Regenerative Medicines in Japan under the ASRM

Cell stem cell
2016 | Journal article
Source: Self-asserted source
Shigeki Sugii

Arp2/3 complex regulates adipogenesis by controlling cortical actin remodelling

Biochemical Journal
2014 | Journal article
EID:

2-s2.0-84911873017

Part of ISSN: 14708728 02646021
Contributors: Yang, W.; Thein, S.; Lim, C.-Y.; Ericksen, R.E.; Sugii, S.; Xu, F.; Robinson, R.C.; Kim, J.B.; Han, W.
Source: Self-asserted source
Shigeki Sugii via Scopus - Elsevier

Arp2/3 complex regulates adipogenesis by controlling cortical actin remodelling

Biochemical Journal
2014 | Journal article
Source: Self-asserted source
Shigeki Sugii

CerS2 haploinsufficiency inhibits $β$-oxidation and confers susceptibility to diet-induced steatohepatitis and insulin resistance

Cell metabolism
2014 | Journal article
Source: Self-asserted source
Shigeki Sugii

CerS2 haploinsufficiency inhibits β-oxidation and confers susceptibility to diet-induced steatohepatitis and insulin resistance

Cell Metabolism
2014 | Journal article
EID:

2-s2.0-84907984591

Part of ISSN: 19327420 15504131
Contributors: Raichur, S.; Wang, S.T.; Chan, P.W.; Li, Y.; Ching, J.; Chaurasia, B.; Dogra, S.; Öhman, M.K.; Takeda, K.; Sugii, S. et al.
Source: Self-asserted source
Shigeki Sugii via Scopus - Elsevier

Erratum: CerS2 haploinsufficiency inhibits β-oxidation and confers susceptibility to diet-induced steatohepatitis and insulin resistance (Cell Metabolism (2014) 20 (687695))

Cell Metabolism
2014 | Journal article
EID:

2-s2.0-84910152859

Part of ISSN: 19327420 15504131
Contributors: Raichur, S.; Wang, S.T.; Chan, P.W.; Li, Y.; Ching, J.; Chaurasia, B.; Dogra, S.; Öhman, M.K.; Takeda, K.; Sugii, S. et al.
Source: Self-asserted source
Shigeki Sugii via Scopus - Elsevier

Evaluation of dietary effects on hepatic lipids in high fat and placebo diet fed rats by in vivo MRS and LC-MS techniques

PLoS ONE
2014 | Journal article
EID:

2-s2.0-84898639621

Part of ISSN: 19326203
Contributors: Yaligar, J.; Gopalan, V.; Kiat, O.W.; Sugii, S.; Shui, G.; Lam, B.D.; Henry, C.J.; Wenk, M.R.; Tai, E.S.; Velan, S.S.
Source: Self-asserted source
Shigeki Sugii via Scopus - Elsevier

Evaluation of dietary effects on hepatic lipids in high fat and placebo diet fed rats by in vivo MRS and LC-MS techniques

PloS one
2014 | Journal article
Source: Self-asserted source
Shigeki Sugii

Frequent co-expression of miRNA-5p and -3p species and cross-targeting in induced pluripotent stem cells

International Journal of Medical Sciences
2014 | Journal article
EID:

2-s2.0-84902078438

Part of ISSN: 14491907
Contributors: Huang, C.-J.; Nhi Nguyen, P.N.; Choo, K.B.; Sugii, S.; Wee, K.; Cheong, S.K.; Kamarul, T.
Source: Self-asserted source
Shigeki Sugii via Scopus - Elsevier

Frequent co-expression of miRNA-5p and-3p species and cross-targeting in induced pluripotent stem cells

Int J Med Sci
2014 | Journal article
Source: Self-asserted source
Shigeki Sugii

Heterogeneity of osteosarcoma cell lines led to variable responses in reprogramming

International Journal of Medical Sciences
2014 | Journal article
EID:

2-s2.0-84906748256

Part of ISSN: 14491907
Contributors: Choong, P.F.; Teh, H.X.; Teoh, H.K.; Ong, H.K.; Choo, K.B.; Sugii, S.; Cheong, S.K.; Kamarul, T.
Source: Self-asserted source
Shigeki Sugii via Scopus - Elsevier

Heterogeneity of osteosarcoma cell lines led to variable responses in reprogramming

International journal of medical sciences
2014 | Journal article
Source: Self-asserted source
Shigeki Sugii

Identification of specific cell-surface markers of adipose-derived stem cells from subcutaneous and visceral fat depots

Stem Cell Reports
2014 | Journal article
EID:

2-s2.0-84893815342

Part of ISSN: 22136711
Contributors: Ong, W.K.; Tan, C.S.; Chan, K.L.; Goesantoso, G.G.; Chan, X.H.D.; Chan, E.; Yin, J.; Yeo, C.R.; Khoo, C.M.; So, J.B.Y. et al.
Source: Self-asserted source
Shigeki Sugii via Scopus - Elsevier
Items per page:
Page 1 of 2

Peer review (5 reviews for 4 publications/grants)

Review activity for iScience. (1)
Review activity for Nature communications (1)
Review activity for Nature food. (1)
Review activity for Trends in biotechnology. (2)