Biography

Education expertise
2015: Ph.D. Zhejiang University, Chemistry.
2011: M.S. Huazhong Agriculture University, Biochemical and Molecular biology.
2008: B.A. Huaihua University, Biology engineering.
Research expertise
2016.6-Present: Associate Professor, College of Science, Huazhong Agricultural University.
2012.5-2014.12: State Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Science.
2011.9-2012.5: Department of chemistry, Zhejiang University.
2008.9-2011.6: National Key Laboratory of Crop Genetic Improvement, College of life science and technology, Huazhong Agriculture University.
Research interests/areas
1. Design and Controlled Preparation of Nanomaterials for Targeted and Controlled Release of Drug Molecules;
2. Construction of an antibiotic - free nano drug system and its treatment for drug - resistant bacterial infection;
3. Nanotherapy strategies for rabies virus infection;

Publication List
（1） Yang Wu#, Zhiyong Song#, Guiyun Deng, Kai Jiang, Huajuan Wang, Xueji Zhang* and Heyou Han*. Gastric Acid Powered Nanomotors Release Antibiotics for In Vivo Treatment of Helicobacter pylori Infection, Small, 2021, 2006877.
（2） Yang Wu, Guiyun Deng, Kai Jiang, Huajuan Wang, Zhiyong Song*, Heyou Han*. Photothermally triggered nitric oxide nanogenerator targeting type IV pili for precise therapy of bacterial infections, Biomaterials, 2021, 120588.
（3） Huajuan Wang#, Jin Zhang#, Zhiyong Song#, Yongli Mu, MF Foda, Yang Wu, Heyou Han*. An intelligent platform based on acidity-triggered aggregation of gold nanoparticles for precise photothermal ablation of focal bacterial infection, Chemical Engineering Journal, 2021, 127076.
（4） Jun Ma#, Zhiyong Song#, Jianhong Yang, Youning Wang, Heyou Han*.Cobalt Ferrite Nanozyme for Efficient Symbiotic Nitrogen Fixation via Regulating Reactive Oxygen Metabolism, Environmental Science: Nano, 2021, 8(1), 188-203.
（5） MeishenRen#, JiaojiaoZhou#, ZhiyongSong, HongMei, MingZhou, Zhen F.Fu, HeyouHan*, LingZhao*. Aptamer and RVG functionalized gold nanorods for targeted photothermal therapy of neurotropic virus infection in the mouse brain, Chemical Engineering Journal, 2021, 128557.
（6） Jianhong Yang#, Zhiyong Song#, Jun Ma, Heyou Han*. Toxicity of Molybdenum-Based Nanomaterials on the Soybean–Rhizobia Symbiotic System: Implications for Nutrition, ACS Applied Nano Materials, 2020, 3, 6, 5773–5782.
（7） Yang Wu#, Zhiyong Song#, Huajuan Wang, Heyou Han*. Endogenous stimulus-powered antibiotic release from nanoreactors for a combination therapy of bacterial infections Nature communications, 2019, 10 (1), 4464.
（8） Shuojun Li#, Zhiyong Song#, Caiyun Liu, Xiaolin Chen*, Heyou Han*. Biomimetic Mineralization-Based CRISPR/Cas9 Ribonucleoprotein Nanoparticles for Gene Editing, ACS Applied Materials & Interfaces, 2019, 11 (51), 47762-47770
（9） Zhiyong Song#, Yang Wu#, Huajuan Wang, Heyou Han*. Synergistic antibacterial effects of curcumin modified silver nanoparticles through ROS-mediated pathways, Materials Science and Engineering: C , 2019, 99, 255-263.
（10） Huajuan Wang#, Zhiyong Song#, Jiangjiang Gu, Shuojun Li, Yang Wu, Heyou Han*. Nitrogen-Doped Carbon Quantum Dots for Preventing Biofilm Formation and Eradicating Drug-Resistant Bacteria Infection, ACS Biomaterials Science Engineering. 2019, 5(9), 4739–4749.
（11） Huajuan Wang, Zhiyong Song, Shuojun Li, Yang Wu, Heyou Han*. One Stone with Two Birds: Functional Gold Nanostar for Targeted Combination Therapy of Drug-Resistant Staphylococcus aureus Infection, ACS Applied Materials & Interfaces, 2019, 2019, 11, 36, 32659–32669.
（12） Zhiyong Song#, Yang Wu#, Qi Cao, Huajuan Wang, Xiangru Wang, Heyou Han*.pH‐Responsive, Light‐Triggered on‐Demand Antibiotic Release from Functional Metal–Organic Framework for Bacterial Infection Combination Therapy, Advanced Functional Materials, 2018, 28 (23), 1800011.
（13） Zhiyong Song, Long Liu, Xiaoyu Wang, Yongqiang Deng, Qingong Nian, Guanchuan Wang, Shunya Zhu, X iaofengLi, Hangyu Zhou, Tao Jiang, Xurong Xu, Ruikang Tang*, Chenfeng Qin*. Intracellular delivery of biomineralized monoclonal antibodies to combat viral infection, Chemical Communications, 2016, 52(9): 1879-1882.
（14） Zhiyong Song, Xiaoyu Wang*, Genxin Zhu, Qinggong Nian, Hangyu Zhou, Dong Yang, Chenfeng Qin, Ruikang Tang*.Virus Capture and Destruction by Label‐Free Graphene Oxide for Detection and Disinfection Applications, Small, 2015, 11 (9-10), 1171-1176.