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Scopus Author ID: 56663124400

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Employment (3)

Chimerna Therapeutics: New York, New York, US

2020-09-01 to present
Employment
Source: Self-asserted source
Jacob Litke

Medical College, Weill Cornell Medicine: NY, NY, US

2020-01-01 to 2020-08-31 | Post Doctoral Researcher (Pharmacology)
Employment
Source: Self-asserted source
Jacob Litke

Massachusetts Institute of Technology: Cambridge, MA, US

2012-04-01 to 2014-06-01 | Laboratory Manager (Chemistry)
Employment
Source: Self-asserted source
Jacob Litke

Education and qualifications (3)

Weill Cornell Medical College: NY, NY, US

2014-07-01 to 2019-12-31 | PhD in Chemical Biology (Pharmacology)
Education
Source: Self-asserted source
Jacob Litke

Wesleyan University: Middletown, CT, US

2010-06 to 2011-06 | Master of Arts (Molecular Biology & Biophysics)
Education
Source: Self-asserted source
Jacob Litke

Wesleyan University: Middletown, CT, US

2006-06-01 to 2010-06-01 | Bachelor of Arts (Molecular Biology & Biochemistry)
Education
Source: Self-asserted source
Jacob Litke

Funding (1)

Engineered circular RNAs: A novel platform for genetically encoded RNA-based biosensors and their application as real-time viral infection reporters

Source: Self-asserted source
Jacob Litke via DimensionsWizard

Works (12)

Designing and Expressing Circular RNA Aptamers to Regulate Mammalian Cell Biology

Methods in Molecular Biology
2023 | Book chapter
DOI: 10.1007/978-1-0716-2695-5_17
Part of ISBN: 9781071626948
Part of ISBN: 9781071626955
Part of ISSN: 1064-3745
Part of ISSN: 1940-6029
Contributors: Jacob L. Litke; Samie R. Jaffrey
Source: Self-asserted source
Jacob Litke

Trans ligation of RNAs to generate hybrid circular RNAs using highly efficient autocatalytic transcripts

Methods
2021-12 | Journal article
DOI: 10.1016/j.ymeth.2021.05.009
Part of ISSN: 1046-2023
Contributors: Jacob L. Litke; Samie R. Jaffrey
Source: Self-asserted source
Jacob Litke

Naturally occurring three-way junctions can be repurposed as genetically encoded RNA-based sensors

Cell Chemical Biology
2021-11 | Journal article
DOI: 10.1016/j.chembiol.2021.04.022
Contributors: Jared D. Moon; Jiahui Wu; Sourav K. Dey; Jacob L. Litke; Xing Li; Hyaeyeong Kim; Samie R. Jaffrey
Source: check_circle
Crossref

Imaging Intracellular S-Adenosyl Methionine Dynamics in Live Mammalian Cells with a Genetically Encoded Red Fluorescent RNA-Based Sensor

Journal of the American Chemical Society
2020-08-19 | Journal article
DOI: 10.1021/jacs.0c02931
Contributors: Xing Li; Liuting Mo; Jacob L. Litke; Sourav Kumar Dey; Scott R. Suter; Samie R. Jaffrey
Source: check_circle
Crossref

Fluorophore‐Promoted RNA Folding and Photostability Enables Imaging of Single Broccoli‐Tagged mRNAs in Live Mammalian Cells

Angewandte Chemie International Edition
2020-03-09 | Journal article
DOI: 10.1002/anie.201914576
Part of ISSN: 1433-7851
Part of ISSN: 1521-3773
Source: Self-asserted source
Jacob Litke

Highly efficient expression of circular RNA aptamers in cells using autocatalytic transcripts

Nature Biotechnology
2019-06-08 | Journal article
DOI: 10.1038/s41587-019-0090-6
Contributors: Jacob L. Litke; Samie R. Jaffrey
Source: check_circle
Crossref

Detection of Low-Abundance Metabolites in Live Cells Using an RNA Integrator

Cell Chemical Biology
2019-02 | Journal article
DOI: 10.1016/j.chembiol.2019.01.005
Part of ISSN: 2451-9456
Contributors: Mingxu You; Jacob L. Litke; Rigumula Wu; Samie R. Jaffrey
Source: Self-asserted source
Jacob Litke via Crossref Metadata Search

Developing Fluorogenic Riboswitches for Imaging Metabolite Concentration Dynamics in Bacterial Cells

Visualizing RNA Dynamics in the Cell
2016 | Other
DOI: 10.1016/bs.mie.2016.03.021
Part of ISBN: 9780128022924
Part of ISSN: 0076-6879
Contributors: J.L. Litke; M. You; S.R. Jaffrey
Source: Self-asserted source
Jacob Litke via Crossref Metadata Search

Probing the ion binding site in a DNA Holliday junction using förster resonance energy transfer (FRET)

International Journal of Molecular Sciences
2016 | Journal article
DOI: 10.3390/ijms17030366
EID:

2-s2.0-84960470173
Contributors: Litke, J.L.; Li, Y.; Nocka, L.M.; Mukerji, I.
Source: Self-asserted source
Jacob Litke via Scopus - Elsevier

Imaging metabolite dynamics in living cells using a Spinach-based riboswitch

Proceedings of the National Academy of Sciences of the United States of America
2015 | Journal article
DOI: 10.1073/pnas.1504354112
EID:

2-s2.0-84930227077
Contributors: You, M.; Litke, J.L.; Jaffrey, S.R.
Source: Self-asserted source
Jacob Litke via Scopus - Elsevier

Structure of DNA Four-Way Junctions: Effect of Ions and Proteins

Biophysical Journal
2012-01 | Journal article
DOI: 10.1016/j.bpj.2011.11.440
Part of ISSN: 0006-3495
Contributors: Ishita Mukerji; C. Iulia Vitoc; Jacob Litke; Elizabeth Wheatley; Olga Buzovetsky; Yan Li; David L. Beveridge
Source: Self-asserted source
Jacob Litke via Crossref Metadata Search

Probing the Ion-Binding Site of the Holliday Junction

Biophysical Journal
2011-02 | Journal article
DOI: 10.1016/j.bpj.2010.12.1958
Part of ISSN: 0006-3495
Contributors: Jacob Litke; Ishita Mukerji
Source: Self-asserted source
Jacob Litke via Crossref Metadata Search
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