Personal information

Genome Instability, DNA replication, DNA repair, Genetic diseases, Checkpoint
Italy

Biography

I lead an independent research group of nine people: a PostDoc fellow, four PhD students, one reseaerch assistant and three MSc intern students.
Our group is involved in the investigation of mechanisms controlling genome stability in human cells during the S-phase of the cell cycle. These pathways are essential to prevent neoplastic transformation. We seek to elucidate the cellular pathways elicited by replication fork arrest and their inherent regulation to identify potential targets for cancer therapy.

Currently, our research projects focus on:
1) The identification of regulatory mechanisms controlling the recovery of perturbed replication forks in normal or pathological conditions;
2) The identification of the role of replication stress in the onset of Werner syndrome and other human genetic diseases How the WRN protein is regulated and the functional implications of the identified PTM on the molecular pathology of Werner syndrome;
3) The identification of cancer-specific replication fork recovery pathways, their implications for cancer genetic instability, and of novel therapeutic approaches that exploit replication stress in tumours.

Activities

Employment (8)

Istituto Superiore di Sanità: Rome, IT

2022-10-01 to present | Director of Research
Employment
Source: Self-asserted source
Pietro Pichierri

Istituto Superiore di Sanità: Roma, Lazio, IT

2019-01-01 to 2022 | Senior Scientist (Environment and health)
Employment
Source: Self-asserted source
Pietro Pichierri

Istituto Superiore di Sanità: Roma, Lazio, IT

2013-06-01 to 2018-12-31 | Senior Researcher (temporary appointment - TD) (Environment and Primary Prevention)
Employment
Source: Self-asserted source
Pietro Pichierri

Istituto Superiore di Sanità: Roma, Lazio, IT

2007-11-01 to 2013-05-31 | Researcher (temporary appointment - TD) (Environment and Primary Prevention)
Employment
Source: Self-asserted source
Pietro Pichierri

Istituto Superiore di Sanità: Roma, Lazio, IT

2004-10-01 to 2007-10-01 | Senior Research Fellow (Environment and Primary Prevention)
Employment
Source: Self-asserted source
Pietro Pichierri

CNRS: Villejuif, FR

2003-01-01 to 2004-09-31 | Post-doc ARC fellow (UPR2169 at the Institut de Cancerologie Gustave Roussy)
Employment
Source: Self-asserted source
Pietro Pichierri

CNRS: Villejuif, FR

2000-11-01 to 2002-12-31 | Post-graduate research fellow (UPR2169)
Employment
Source: Self-asserted source
Pietro Pichierri

Universita' degli Studi della Tuscia: Viterbo, IT

1996-04-01 to 2000-10-31 | Post-graduate fellow
Employment
Source: Self-asserted source
Pietro Pichierri

Education and qualifications (3)

CNRS: Villejuif, FR

2003-12-01 to 2004-09-01 | Post-doctoral training (UPR2169 at Institut de Cancerologie Gustave Roussy)
Education
Source: Self-asserted source
Pietro Pichierri

Universita' degli Studi della Tuscia: Viterbo, IT

2000-11-01 to 2003-12-23 | PhD
Education
Source: Self-asserted source
Pietro Pichierri

Universita' degli Studi della Tuscia: Viterbo, IT

1989-11-01 to 1995-12-31 | BSc + MSc
Education
Source: Self-asserted source
Pietro Pichierri

Professional activities (8)

Sapienza – Università di Roma: Rome, IT

2025-01-01 to present | Faculty - PhD course in Human Biology and Medical Genetics (Molecular Medicine)
Invited position
Source: Self-asserted source
Pietro Pichierri

A-IATRIS: Roma, Lazio, IT

2019-06-01 to present | Chair of the A-IATRIS small molecule platform
Service
Source: Self-asserted source
Pietro Pichierri

International Agency for Research on Cancer: Lyon, Rhône-Alpes, FR

2019-05-01 to present | Member of the Scientific Committee
Membership
Source: Self-asserted source
Pietro Pichierri

Istituto Nazionale Biostrutture e Biosistemi: Roma, Lazio, IT

2018-04-17 to present | Associate Scientist
Invited position
Source: Self-asserted source
Pietro Pichierri

Ministry of Education, Universities and Research: Rome, IT

2017-04-14 | National habilitation to Full Professorship in Applied Biology
Distinction
Source: Self-asserted source
Pietro Pichierri

Ministry of Education, Universities and Research: Rome, IT

2017-04-10 | National habilitation to Full Professorship in Molecular Biology
Distinction
Source: Self-asserted source
Pietro Pichierri

Ministry of Education, Universities and Research: Rome, IT

2017-04-04 | National habilitation to Full Professorship in Genetics
Distinction
Source: Self-asserted source
Pietro Pichierri

Ministry of Education, Universities and Research: Rome, IT

2017-03-28 | National habilitation to Associate Professorship in Pathology
Distinction
Source: Self-asserted source
Pietro Pichierri

Funding (19)

Investigating the molecular network defining the WRN-MSI synthetic lethal relationship in colorectal cancer

2025-10 to 2028-09 | Grant
Worldwide Cancer Research (Edinburgh, GB)
Source: Self-asserted source
Pietro Pichierri

Defining novel factors regulating gap formation at perturbed DNA replication forks in normal and cancer cells

2025-01 to 2030-01 | Grant
Fondazione AIRC per la ricerca sul cancro ETS (Milan, IT)
GRANT_NUMBER:

28972

Source: Self-asserted source
Pietro Pichierri

Determining how a Werner helicase (WRN) tumor suppressor complex regulates the human papillomavirus 16 life cycle

2021-06 to 2026-05 | Grant
National Institutes of Health (Md., Md., US)
Source: Self-asserted source
Pietro Pichierri

The role of human RAD52 protein in genome stability

2019-04 to 2024-04 | Grant
National Institutes of Health (Md., Md., US)
Source: Self-asserted source
Pietro Pichierri

Novel functions of RAD52 in protection of perturbed DNA replication and implication for genome instability of cancer

2019-01 to 2024-12 | Grant
Fondazione Italiana per la Ricerca sul Cancro (Milan, IT)
Source: Self-asserted source
Pietro Pichierri

Generazione di un modello cellulare per lo studio delle basi molecolari della Immunodisplasia ossea di Schimke

2016-11 to 2018-12 | Grant
Fondazione Terzo Pilastro Internazionale (Rome, IT)
Source: Self-asserted source
Pietro Pichierri

Investigating the molecular mechanism leading to genome instability in tumors: analysis of role of the replication stress response and its potential for early diagnosis and target therapy of cancer

2016-10 to 2022-06 | Grant
Ministero della Salute (Rome, IT)
GRANT_NUMBER:

RF-2016-02362022

Source: Self-asserted source
Pietro Pichierri

Generation of an in vitro model to investigate replicative stress as the possible molecular mechanism underlying Schimke immuno-osseous dysplasia

2016-10 to 2017-12 | Grant
Fondazione Telethon (Milan, IT)
GRANT_NUMBER:

GEP15050

Source: Self-asserted source
Pietro Pichierri

Novel roles of WRN protein in response to replication stress induced by anti-cancer drugs and implications for therapy

2016-01 to 2018-12 | Grant
Associazione Italiana per la Ricerca sul Cancro (Milan, IT)
Source: Self-asserted source
Pietro Pichierri

“Analysis of the senataxin role in DNA damage response to define the molecular mechanism underlying the neurological disease Ataxia with Oculomotor Apraxia type 2"

2014-06 to 2016-06 | Grant
Fondazione Cariplo (Milan, IT)
Source: Self-asserted source
Pietro Pichierri

“Functional analysis of MUS81/EME1 regulation by checkpoint kinases and its implications for genome stability"

2013-12 to 2015-12 | Grant
Associazione Italiana per la Ricerca sul Cancro (Milan, IT)
Source: Self-asserted source
Pietro Pichierri

“Investigating the DNA replication stress response and its potential for diagnosis and target therapy of cancer "

2013-10 to 2015-02 | Grant
Nando-Peretti Foundation (Rome, IT)
Source: Self-asserted source
Pietro Pichierri

“Uncovering the molecular pathology of Werner syndrome: analysis of the functional relationship between ATR-related WRN function, replication stress and premature cellular senescence”

2012-10 to 2016-11 | Grant
Fondazione Telethon (Milan, IT)
GRANT_NUMBER:

GGP12144

Source: Self-asserted source
Pietro Pichierri

“Assessing the role of WRN and MUS81 in the response to oncogene-induced replication stress"

2009-11 to 2012-12 | Grant
Associazione Italiana per la Ricerca sul Cancro (Milan, IT)
Source: Self-asserted source
Pietro Pichierri

“Analysis of alternative pathway activated by replication stress in the cancer-prone disease Werner syndrome: implications for a non-toxic therapy of cancer with specific defects in replication fork recovery”

2007-10 to 2009-10 | Grant
AICR (St. Andrews, GB)
Source: Self-asserted source
Pietro Pichierri

“Genotype-phenotype analysis of neurodegenerative and aging-prone syndromes caused by mutations in the DNA damage response/repair pathway”

2007-05 to 2009-12 | Grant
NIH-ISS (Rome, IT)
Source: Self-asserted source
Pietro Pichierri

“The WRN helicase and the maintenance of genome stability during DNA replication”

2006-11 to 2009-12 | Grant
Associazione Italiana per la Ricerca sul Cancro (Milan, IT)
Source: Self-asserted source
Pietro Pichierri

“Role of the Werner syndrome helicase in genome stability”

2004-11 to 2007-10 | Grant
Fondazione Telethon (Milan, IT)
GRANT_NUMBER:

GGP04094

Source: Self-asserted source
Pietro Pichierri

Young Investigator award

2004-09 to 2005-09 | Award
Italian Association on Environmental Mutagenesis (SIMA) (Rome, IT)
Source: Self-asserted source
Pietro Pichierri

Works (50 of 67)

Items per page:
Page 1 of 2

WRNIP1 prevents transcription-associated genomic instability

eLife
2024-03-15 | Journal article
Contributors: Pasquale Valenzisi; Veronica Marabitti; Pietro Pichierri; Annapaola Franchitto
Source: check_circle
Crossref

Functional correlation between WRN and SAMHD1 in end-resection

2024-02-16 | Preprint
Contributors: Benedetta Perdichizzi; Pietro Pichierri
Source: check_circle
Crossref

WRNIP1 prevents transcription-associated genomic instability

2023-08-31 | Preprint
Contributors: Pasquale Valenzisi; Veronica Marabitti; Pietro Pichierri; Annapaola Franchitto
Source: check_circle
Crossref

Phosphorylation status of MUS81 is a modifier of Olaparib sensitivity in BRCA2-deficient cells

Nucleic Acids Research
2023-07-21 | Journal article
Contributors: Francesca Blandino; Eva Malacaria; Carolina Figlioli; Alessandro Noto; Giusj Monia Pugliese; Annapaola Franchitto; Pietro Pichierri
Source: check_circle
Crossref

WRNIP1 prevents transcription-associated genomic instability

2023-06-24 | Preprint
Contributors: Pasquale Valenzisi; Veronica Marabitti; Pietro Pichierri; Annapaola Franchitto
Source: check_circle
Crossref

RAD52 prevents accumulation of Polalpha-dependent replication gaps at perturbed replication forks in human cells

2023-04-12 | Preprint
Contributors: Ludovica Di Biagi; Giorgia Marozzi; Eva Malacaria; Masayoshi Honda; FRANCESCA ANTONELLA Aiello; Pasquale Valenzisi; Maria Spies; Annapaola Franchitto; Pietro Pichierri
Source: check_circle
Crossref

Therapeutic disruption of RAD52–ssDNA complexation via novel drug-like inhibitors

NAR Cancer
2023-03-11 | Journal article
Contributors: Divya S Bhat; Eva Malacaria; Ludovica Di Biagi; Mortezaali Razzaghi; Masayoshi Honda; Kathryn F Hobbs; Sarah R Hengel; Pietro Pichierri; M Ashley Spies; Maria Spies
Source: check_circle
Crossref

WRNIP1 PREVENTS G4/R-LOOP-ASSOCIATED GENOMIC INSTABILITY

2022-12-18 | Preprint
Contributors: Pasquale Valenzisi; Veronica Marabitti; Stefano Petrai; Francesca Rita Giardinelli; Pietro Pichierri; Annapaola Franchitto
Source: check_circle
Crossref

CHK2 Regulates MUS81-EME2 Function in Response to Replication Stress and BRCA2 Deficiency

2022-10-08 | Preprint
Contributors: Eva Malacaria; Anita Palma; Sara Rinalducci; Annapaola Franchitto; Pietro Pichierri
Source: check_circle
Crossref

Phosphorylation Status Of MUS81 Is A Modifier Of Olaparib Sensitivity In BRCA2-Deficient Cells

2022-08-14 | Preprint
Contributors: Francesca Blandino; Eva Malacaria; Carolina Figlioli; Alessandro Noto; Giusj Monia Pugliese; Annapaola Franchitto; Pietro Pichierri
Source: check_circle
Crossref

R-Loop-Associated Genomic Instability and Implication of WRN and WRNIP1

International Journal of Molecular Sciences
2022-01-28 | Journal article
Contributors: Veronica Marabitti; Pasquale Valenzisi; Giorgia Lillo; Eva Malacaria; Valentina Palermo; Pietro Pichierri; Annapaola Franchitto
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Control of replication stress and mitosis in colorectal cancer stem cells through the interplay of PARP1, MRE11 and RAD51.

Cell death and differentiation
2021-02-02 | Journal article
Source: Self-asserted source
Pietro Pichierri

Using a Human Papillomavirus Model to Study DNA Replication and Repair of Wild Type and Damaged DNA Templates in Mammalian Cells.

International journal of molecular sciences
2020-10-13 | Journal article
Source: Self-asserted source
Pietro Pichierri

Reverse transcriptase inhibitors promote the remodelling of nuclear architecture and induce autophagy in prostate cancer cells.

Cancer letters
2020-02-26 | Journal article
Source: Self-asserted source
Pietro Pichierri

Physiological and Pathological Roles of RAD52 at DNA Replication Forks.

Cancers
2020-02-10 | Journal article
Source: Self-asserted source
Pietro Pichierri

Checkpoint Defects Elicit a WRNIP1-Mediated Response to Counteract R-Loop-Associated Genomic Instability.

Cancers
2020-02-07 | Journal article
Source: Self-asserted source
Pietro Pichierri

Checkpoint defects require WRNIP1 to counteract R-loop-associated genomic instability

2019-11-29 | Other
Contributors: Veronica Marabitti; Giorgia Lillo; Eva Malacaria; Valentina Palermo; Pietro Pichierri; Annapaola Franchitto
Source: check_circle
Crossref

Inducible SMARCAL1 knockdown in iPSC reveals a link between replication stress and altered expression of master differentiation genes

Disease Models & Mechanisms
2019-10-01 | Journal article
Contributors: Giusj Monia Pugliese; Federico Salaris; Valentina Palermo; Veronica Marabitti; Nicolò Morina; Alessandro Rosa; Annapaola Franchitto; Pietro Pichierri
Source: check_circle
Crossref

Author Correction: Rad52 prevents excessive replication fork reversal and protects from nascent strand degradation

Nature Communications
2019-05-01 | Journal article
Contributors: Eva Malacaria; Giusj Monia Pugliese; Masayoshi Honda; Veronica Marabitti; Francesca Antonella Aiello; Maria Spies; Annapaola Franchitto; Pietro Pichierri
Source: check_circle
Crossref

Rad52 prevents excessive replication fork reversal and protects from nascent strand degradation

Nature Communications
2019-03-29 | Journal article
Contributors: Eva Malacaria; Giusj Monia Pugliese; Masayoshi Honda; Veronica Marabitti; Francesca Antonella Aiello; Maria Spies; Annapaola Franchitto; Pietro Pichierri
Source: check_circle
Crossref

Switch-Like Phosphorylation of WRN Integrates End-Resection with RAD51 Metabolism at Collapsed Replication Forks

2018-08-29 | Preprint
Contributors: Valentina Palermo; Eva Malacaria; Maurizio Semproni; Benedetta Perdichizzi; Pasquale Valenzisi; Massimo Sanchez; Federica Marini; Achille Pellicioli; Annapaola Franchitto; Pietro Pichierri
Source: check_circle
Crossref

Rad51 and Mitotic Function of Mus81 are Essential for Recovery from Low-Dose of Camptothecin in the Absence of the Wrn Exonuclease

2018-08-25 | Other
Contributors: Francesca Antonella Aiello; Anita Palma; Eva Malacaria; Li Zheng; Judith L. Campbell; Binghui Shen; Annapaola Franchitto; Pietro Pichierri
Source: check_circle
Crossref

SLX4 prevents GEN1-dependent DSBs during DNA replication arrest under pathological conditions in human cells

Scientific Reports
2017 | Journal article
EID:

2-s2.0-85015342334

Contributors: Malacaria, E.; Franchitto, A.; Pichierri, P.
Source: Self-asserted source
Pietro Pichierri via Scopus - Elsevier

Small-molecule inhibitors identify the RAD52-ssDNA interaction as critical for recovery from replication stress and for survival of BRCA2 deficient cells

eLife
2016 | Journal article
EID:

2-s2.0-84983032668

Contributors: Hengel, S.R.; Malacaria, E.; Da Silva Constantino, L.F.; Bain, F.E.; Diaz, A.; Koch, B.G.; Yu, L.; Wu, M.; Pichierri, P.; Spies, M.A. et al.
Source: Self-asserted source
Pietro Pichierri via Scopus - Elsevier

WRNIP1 protects stalled forks from degradation and promotes fork restart after replication stress

Embo Journal
2016 | Journal article
WOSUID:

WOS:000378929900006

Contributors: Leuzzi, Giuseppe; Marabitti, Veronica; Pichierri, Pietro; Franchitto, Annapaola
Source: Self-asserted source
Pietro Pichierri via ResearcherID
grade
Preferred source (of 2)‎

CDK1 phosphorylates WRN at collapsed replication forks

Nature Communications
2016-09-16 | Journal article
Contributors: Valentina Palermo; Sara Rinalducci; Massimo Sanchez; Francesca Grillini; Joshua A. Sommers; Robert M. Brosh, Jr; Lello Zolla; Annapaola Franchitto; Pietro Pichierri
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

MUTYH mediates the toxicity of combined DNA 6-thioguanine and UVA radiation

Oncotarget
2015 | Journal article
WOSUID:

WOS:000354885300010

Contributors: Grasso, Francesca; Ruggieri, Vitalba; De Luca, Gabriele; Leopardi, Paola; Mancuso, Maria Teresa; Casorelli, Ida; Pichierri, Pietro; Karran, Peter; Bignami, Margherita
Source: Self-asserted source
Pietro Pichierri via ResearcherID

The WRN exonuclease domain protects nascent strands from pathological MRE11/EXO1-dependent degradation.

2015-08 | Journal article
Contributors: Iannascoli C; Palermo V; Murfuni I; Franchitto A; Pichierri P
Source: Self-asserted source
Pietro Pichierri via Europe PubMed Central
grade
Preferred source (of 2)‎

Checkpoint-dependent and independent roles of the Werner syndrome protein in preserving genome integrity in response to mild replication stress

Nucleic Acids Research
2014 | Journal article
WOSUID:

WOS:000347693200029

Contributors: Basile, Giorgia; Leuzzi, Giuseppe; Pichierri, Pietro; Franchitto, Annapaola
Source: Self-asserted source
Pietro Pichierri via ResearcherID
grade
Preferred source (of 2)‎

Replication fork recovery and regulation of common fragile sites stability

Cellular and Molecular Life Sciences
2014 | Journal article
WOSUID:

WOS:000345085000004

Contributors: Franchitto, Annapaola; Pichierri, Pietro
Source: Self-asserted source
Pietro Pichierri via ResearcherID
grade
Preferred source (of 2)‎

Survival of the Replication Checkpoint Deficient Cells Requires MUS81-RAD52 Function

Plos Genetics
2013 | Journal article
WOSUID:

WOS:000330367200073

Contributors: Murfuni, Ivana; Basile, Giorgia; Subramanyam, Shyamal; Malacaria, Eva; Bignami, Margherita; Spies, Maria; Franchitto, Annapaola; Pichierri, Pietro
Source: Self-asserted source
Pietro Pichierri via ResearcherID
grade
Preferred source (of 2)‎

The WRN and MUS81 proteins limit cell death and genome instability following oncogene activation

Oncogene
2013 | Journal article
Contributors: Murfuni, I.; Nicolai, S.; Baldari, S.; Crescenzi, M.; Bignami, M.; Franchitto, A.; Pichierri, P.
Source: Self-asserted source
Pietro Pichierri via ResearcherID
grade
Preferred source (of 2)‎

Werner Syndrome Helicase Has a Critical Role in DNA Damage Responses in the Absence of a Functional Fanconi Anemia Pathway

Cancer Research
2013 | Journal article
WOSUID:

WOS:000324114400020

Contributors: Aggarwal, Monika; Banerjee, Taraswi; Sommers, Joshua A.; Iannascoli, Chiara; Pichierri, Pietro; Shoemaker, Robert H.; Brosh, Robert M., Jr.
Source: Self-asserted source
Pietro Pichierri via ResearcherID
grade
Preferred source (of 2)‎

Perturbed replication induced genome wide or at common fragile sites is differently managed in the absence of WRN

Carcinogenesis
2012 | Journal article
Contributors: Murfuni, I.; De Santis, A.; Federico, M.; Bignami, M.; Pichierri, P.; Franchitto, A.
Source: Self-asserted source
Pietro Pichierri via ResearcherID
grade
Preferred source (of 2)‎

Targeting mismatch repair: A challenge for personalized chemotherapy

Drug Discovery Today: Disease Models
2012 | Journal article
EID:

2-s2.0-84862200846

Contributors: Pichierri, P.; Bignami, M.
Source: Self-asserted source
Pietro Pichierri via Scopus - Elsevier

The RAD9-RAD1-HUS1 (9.1.1) complex interacts with WRN and is crucial to regulate its response to replication fork stalling

Oncogene
2012 | Journal article
Contributors: Pichierri, P.; Nicolai, S.; Cignolo, L.; Bignami, M.; Franchitto, A.
Source: Self-asserted source
Pietro Pichierri via ResearcherID
grade
Preferred source (of 2)‎

The Werner Syndrome protein: Linking the replication checkpoint response to genome stability

Aging
2011 | Journal article
EID:

2-s2.0-80051662527

Contributors: Pichierri, P.; Ammazzalorso, F.; Bignami, M.; Franchitto, A.
Source: Self-asserted source
Pietro Pichierri via Scopus - Elsevier

Understanding the molecular basis of common fragile sites instability: Role of the proteins involved in the recovery of stalled replication forks

Cell Cycle
2011 | Journal article
EID:

2-s2.0-82855169522

Contributors: Franchitto, A.; Pichierri, P.
Source: Self-asserted source
Pietro Pichierri via Scopus - Elsevier

ATR and ATM differently regulate WRN to prevent DSBs at stalled replication forks and promote replication fork recovery

EMBO Journal
2010 | Journal article
EID:

2-s2.0-77956881105

Contributors: Ammazzalorso, F.; Pirzio, L.M.; Bignami, M.; Franchitto, A.; Pichierri, P.
Source: Self-asserted source
Pietro Pichierri via Scopus - Elsevier

Replication fork stalling in WRN-deficient cells is overcome by prompt activation of a MUS81-dependent pathway

Journal of Cell Biology
2008 | Journal article
EID:

2-s2.0-55949108120

Contributors: Franchitto, A.; Pirzio, L.M.; Prosperi, E.; Sapora, O.; Bignami, M.; Pichierri, P.
Source: Self-asserted source
Pietro Pichierri via Scopus - Elsevier

Werner syndrome helicase activity is essential in maintaining fragile site stability

Journal of Cell Biology
2008 | Journal article
EID:

2-s2.0-38749136967

Contributors: Pirzio, L.M.; Pichierri, P.; Bignami, M.; Franchitto, A.
Source: Self-asserted source
Pietro Pichierri via Scopus - Elsevier

Interplay between wrn and the checkpoint in s-phase

Italian Journal of Biochemistry
2007 | Journal article
EID:

2-s2.0-34547652552

Contributors: Pichierri, P.
Source: Self-asserted source
Pietro Pichierri via Scopus - Elsevier

Replication-dependent DNA damage response triggered by roscovitine induces an uncoupling of DNA replication proteins

Cell Cycle
2006 | Journal article
EID:

2-s2.0-33749658586

Contributors: Savio, M.; Cerri, M.; Cazzalini, O.; Perucca, P.; Stivala, L.A.; Pichierri, P.; Franchitto, A.; Meijer, L.; Prosperi, E.
Source: Self-asserted source
Pietro Pichierri via Scopus - Elsevier

BLM and the FANC proteins collaborate in a common pathway in response to stalled replication forks

EMBO Journal
2004 | Journal article
EID:

2-s2.0-4143141093

Contributors: Pichierri, P.; Franchitto, A.; Rosselli, F.
Source: Self-asserted source
Pietro Pichierri via Scopus - Elsevier

Fanconi anemia proteins and the S phase checkpoint

Cell Cycle
2004 | Journal article
EID:

2-s2.0-13244298119

Contributors: Pichierri, P.; Rosselli, F.
Source: Self-asserted source
Pietro Pichierri via Scopus - Elsevier

The DNA crosslink-induced S-phase checkpoint depends on ATR-CHK1 and ATR-NBS1-FANCD2 pathways

EMBO Journal
2004 | Journal article
EID:

2-s2.0-1842576658

Contributors: Pichierri, P.; Rosselli, F.
Source: Self-asserted source
Pietro Pichierri via Scopus - Elsevier

Werner syndrome protein and the MRE11 complex are involved in a common pathway of replication fork recovery

Cell Cycle
2004 | Journal article
EID:

2-s2.0-13944255048

Contributors: Franchitto, A.; Pichierri, P.
Source: Self-asserted source
Pietro Pichierri via Scopus - Elsevier

The Fanconi anemia pathway and the DNA interstrand cross-links repair

Biochimie
2003 | Journal article
EID:

2-s2.0-0942289901

Contributors: Rosselli, F.; Briot, D.; Pichierri, P.
Source: Self-asserted source
Pietro Pichierri via Scopus - Elsevier

The G<inf>2</inf>-phase decatenation checkpoint is defective in Werner syndrome cells

Cancer Research
2003 | Journal article
EID:

2-s2.0-0038068983

Contributors: Franchitto, A.; Oshima, J.; Pichierri, P.
Source: Self-asserted source
Pietro Pichierri via Scopus - Elsevier

The mammalian mismatch repair protein MSH2 is required for correct MRE11 and RAD51 relocalization and for efficient cell cycle arrest induced by ionizing radiation in G2 phase

Oncogene
2003 | Journal article
EID:

2-s2.0-0038297562

Contributors: Franchitto, A.; Pichierri, P.; Piergentili, R.; Crescenzi, M.; Bignami, M.; Palitti, F.
Source: Self-asserted source
Pietro Pichierri via Scopus - Elsevier
Items per page:
Page 1 of 2

Peer review (7 reviews for 5 publications/grants)

Review activity for Communications biology. (1)
Review activity for EMBO journal. (1)
Review activity for Nature (1)
Review activity for Nature communications (2)
Review activity for PLOS genetics. (2)