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Employment (3)

Indiana University School of Medicine: Indianapolis, US

2020-01-01 to present | Professor and Chair (Microbiology and Immunology)
Employment
Source: Self-asserted source
Mark Kaplan

Indiana University School of Medicine: Indianapolis, IN, US

2005-07 to 2019-12-31 | Professor (Pediatrics)
Employment
Source: Self-asserted source
Mark Kaplan

Indiana University School of Medicine: Indianapolis, IN, US

1998-01 to 2005-06 | Faculty (Microbiology)
Employment
Source: Self-asserted source
Mark Kaplan

Education and qualifications (2)

Wayne State University School of Medicine: Detroit, MI, US

1987-09 to 1992-12 | Ph.D. (Immunology and Microbiology)
Education
Source: Self-asserted source
Mark Kaplan

University of Windsor Faculty of Science: Windsor, ON, CA

1983-09 to 1987-05 | B.Sc. (Biology)
Education
Source: Self-asserted source
Mark Kaplan

Funding (11)

Granzyme A-secreting T cells in allergic inflammation

2015-07-16 to 2017-06-30 | Grant
National Institute of Allergy and Infectious Diseases (Bethesda, US)
GRANT_NUMBER: 1R21AI117380-01
GRANT_NUMBER: 1R21AI117380-01
Source: Self-asserted source
Mark Kaplan via DimensionsWizard

Regulation of Humoral Immunity by Tox

2015-07-01 to 2017-06-30 | Grant
National Institute of Allergy and Infectious Diseases (Bethesda, US)
GRANT_NUMBER: 1R03AI119623-01
GRANT_NUMBER: 1R03AI119623-01
Source: Self-asserted source
Mark Kaplan via DimensionsWizard

STAT3 in T helper cell development

2012-05-01 to 2014-04-30 | Grant
National Institute of Allergy and Infectious Diseases (Bethesda, US)
GRANT_NUMBER: 5R03AI101628-02
GRANT_NUMBER: 5R03AI101628-02
Source: Self-asserted source
Mark Kaplan via DimensionsWizard
grade
Preferred source (of 2)‎

Cytokine regulation of skin barrier function

2012-02-15 to 2017-01-31 | Grant
National Institute of Allergy and Infectious Diseases (Bethesda, US)
GRANT_NUMBER: 5R01AI095282-03
GRANT_NUMBER: 5R01AI095282-03
Source: Self-asserted source
Mark Kaplan via DimensionsWizard

Cytokine regulation of skin barrier function

2012-02-15 to 2017-01-31 | Grant
National Institute of Allergy and Infectious Diseases (Bethesda, US)
GRANT_NUMBER: 5R01AI095282-04
GRANT_NUMBER: 5R01AI095282-04
Source: Self-asserted source
Mark Kaplan via DimensionsWizard

PARP activity in allergic inflammation

2009-08-01 to 2014-07-31 | Grant
National Heart, Lung, and Blood Institute (Bethesda, US)
GRANT_NUMBER: 5R01HL093105-04
GRANT_NUMBER: 5R01HL093105-04
Source: Self-asserted source
Mark Kaplan via DimensionsWizard
grade
Preferred source (of 2)‎

Role of IL-17-secreting T cells in anti-viral immunity

2007-08-15 to 2010-07-31 | Grant
National Institute of Allergy and Infectious Diseases (Bethesda, US)
GRANT_NUMBER: 5R21AI077091-02
GRANT_NUMBER: 5R21AI077091-02
Source: Self-asserted source
Mark Kaplan via DimensionsWizard
grade
Preferred source (of 2)‎

Pathogenesis of Atopic Dermatitis

2006-06-15 to 2011-05-31 | Grant
National Institute of Allergy and Infectious Diseases (Bethesda, US)
GRANT_NUMBER: 5U19AI070448-05
GRANT_NUMBER: 5U19AI070448-05
Source: Self-asserted source
Mark Kaplan via DimensionsWizard
grade
Preferred source (of 2)‎

The role of PU.1 in T helper cell heterogeneity

2003-12-01 to 2015-04-30 | Grant
National Institute of Allergy and Infectious Diseases (Bethesda, US)
GRANT_NUMBER: 5R01AI057459-10
GRANT_NUMBER: 5R01AI057459-10
Source: Self-asserted source
Mark Kaplan via DimensionsWizard
grade
Preferred source (of 2)‎

Stat4 Immunobiology

1999-08-01 to 2015-04-30 | Grant
National Institute of Allergy and Infectious Diseases (Bethesda, US)
GRANT_NUMBER: 5R01AI045515-15
GRANT_NUMBER: 5R01AI045515-15
Source: Self-asserted source
Mark Kaplan via DimensionsWizard
grade
Preferred source (of 2)‎

Stat4 Immunobiology

1999-08-01 to 2010-04-30 | Grant
National Institute of Allergy and Infectious Diseases (Bethesda, US)
GRANT_NUMBER: 2R56AI045515-11
GRANT_NUMBER: 2R56AI045515-11
Source: Self-asserted source
Mark Kaplan via DimensionsWizard
grade
Preferred source (of 2)‎

Works (50 of 99)

Items per page:
Page 1 of 2

Case Studies of Sustained Remission of Membranous Glomerulonephritis With Dupilumab Treatment

Kidney International Reports
2024-12 | Journal article
Contributors: Mark H. Kaplan; Jessica M. Greco; Brad H. Rovin; Anthony M. Cannon; Abigail Pajulas; Jeffrey B. Travers; Ayman Hallab; Matthew J. Turner
Source: check_circle
Crossref

The Impact of Cell-Intrinsic STAT6 Protein on Donor T Cell-Mediated Graft-Versus-Tumor Effect

International Journal of Molecular Sciences
2024-12-31 | Journal article
Contributors: Xiaoqun Guan; Hope Fury; Priya D. Issuree; Tyler Atagozli; Emory E. McManimon; Peng Shao; Yue Li; Michael Chimenti; Noah S. Butler; Mark H. Kaplan et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Activin A Promotes Differentiation of a Pathogenic Multicytokine IL-9-secreting CD4+ T Cell Population

The Journal of Immunology
2024-09-15 | Journal article
Contributors: Benjamin J Ulrich; Wenwu Zhang; Blake T Kenworthy; Rakshin Kharwadkar; Matthew R Olson; Mark H Kaplan
Source: check_circle
Crossref

TL1A priming induces a multi-cytokine Th9 cell phenotype that promotes robust allergic inflammation in murine models of asthma

Mucosal Immunology
2024-08 | Journal article
Contributors: Michelle L. Niese; Abigail L. Pajulas; Cameron R. Rostron; Cherry C.L. Cheung; Maya S. Krishnan; Jilu Zhang; Anthony M. Cannon; Mark H. Kaplan
Source: check_circle
Crossref

An IL-23-STAT4 pathway is required for the proinflammatory function of classical dendritic cells during CNS inflammation

Proceedings of the National Academy of Sciences
2024-08-06 | Journal article
Contributors: Nada S. Alakhras; Wenwu Zhang; Nicolas Barros; Anchal Sharma; James Ropa; Raj Priya; X. Frank Yang; Mark H. Kaplan
Source: check_circle
Crossref

Diminished γδ T Cells during Murine Allergic Skin Inflammation Is Mediated by IL-4 Signaling in Keratinocytes

The Journal of Immunology
2024-07-15 | Journal article
Contributors: Wenwu Zhang; Abigail Pajulas; Michelle Niese; Hongming Zhou; Jennifer Zhao; Nahid Akhtar; Matthew J Turner; Mark H Kaplan
Source: check_circle
Crossref

Fibronectin Promotes Wound Healing in an Atopic Human Skin Xenografting Model

Journal of Investigative Dermatology
2024-06 | Journal article
Contributors: Wenwu Zhang; Nahid Akhtar; Jennifer Zhao; Dan F. Spandau; Mark H. Kaplan
Source: check_circle
Crossref

Loricrin and Cytokeratin Disorganisation in Severe Forms of Periodontitis

International Dental Journal
2023-12 | Journal article
Contributors: Raisa Queiroz Catunda; Karen Ka-yan Ho; Srushti Patel; Christopher Bryant Roy; Maria Alexiou; Liran Levin; Benjamin J. Ulrich; Mark H. Kaplan; Maria Febbraio
Source: check_circle
Crossref

STAT3 Signaling Heterogeneity Underlies Cytokine-Expressing Fate in Th17 Cultures

ImmunoHorizons
2023-11-01 | Journal article
Contributors: Michelle L Niese; Nicole Glosson-Byers; Ana Paula Moreira Serezani; Nada S Alakhras; Mark H Kaplan
Source: check_circle
Crossref

Submit to ImmunoHorizons or I Will Write Another Editorial

ImmunoHorizons
2023-10-01 | Journal article
Contributors: Mark H. Kaplan
Source: check_circle
Crossref

Dendritic Cells as a Nexus for the Development of Multiple Sclerosis and Models of Disease

Advanced Biology
2023-07 | Journal article
Contributors: Nada S. Alakhras; Mark H. Kaplan
Source: check_circle
Crossref

The World according to IL-9

The Journal of Immunology
2023-07-01 | Journal article
Contributors: Abigail Pajulas; Jilu Zhang; Mark H Kaplan
Source: check_circle
Crossref

The Dichotomy of Interleukin-9 Function in the Tumor Microenvironment

Journal of Interferon & Cytokine Research
2023-06-01 | Journal article
Contributors: Anthony Cannon; Abigail Pajulas; Mark H. Kaplan; Jilu Zhang
Source: check_circle
Crossref

Inhibition of the mitochondrial pyruvate carrier simultaneously mitigates hyperinflammation and hyperglycemia in COVID-19

Science Immunology
2023-04-14 | Journal article
Contributors: Bibo Zhu; Xiaoqin Wei; Harish Narasimhan; Wei Qian; Ruixuan Zhang; In Su Cheon; Yue Wu; Chaofan Li; Russell G. Jones; Mark H. Kaplan et al.
Source: check_circle
Crossref

Age-related decline in LEPR+ hematopoietic stem cell function

Leukemia
2023-03 | Journal article
Contributors: Thao Trinh; James Ropa; Scott Cooper; Arafat Aljoufi; Anthony Sinn; Maegan Capitano; Hal E. Broxmeyer; Mark H. Kaplan
Source: check_circle
Crossref

ERG Functionally Overlaps with Other Ets Proteins in Promoting TH9 Cell Expression of Il9 during Allergic Lung Inflammation

The Journal of Immunology
2023-03-01 | Journal article
Contributors: Rakshin Kharwadkar; Benjamin J Ulrich; Michelle Chu; Byunghee Koh; Matthew M Hufford; Yongyao Fu; Graeme M Birdsey; Bo T Porse; Anna M Randi; Mark H Kaplan
Source: check_circle
Crossref

Chronic developmental hypoxia alters rat lung immune cell transcriptomes during allergic airway inflammation

Physiological Reports
2023-02 | Journal article
Contributors: Michelle Chu; Huanling Gao; Patricia Esparza; Abigail Pajulas; Jocelyn Wang; Rakshin Kharwadkar; Hongyu Gao; Mark H. Kaplan; Robert S. Tepper
Source: check_circle
Crossref

γδ T Cell‒Mediated Wound Healing Is Diminished by Allergic Skin Inflammation

Journal of Investigative Dermatology
2022-10 | Journal article
Contributors: Jocelyn Wang; Abigail Pajulas; Yongyao Fu; Djamilatou Adom; Wenwu Zhang; Andrew S. Nelson; Dan F. Spandau; Mark H. Kaplan
Source: check_circle
Crossref

γδ T cell IFNγ production is directly subverted by Yersinia pseudotuberculosis outer protein YopJ in mice and humans

PLOS Pathogens
2021-12-06 | Journal article
Contributors: Timothy H. Chu; Denise M. Monack; Camille Khairallah; Jason Shieh; Rhea Cho; Zhijuan Qiu; Yue Zhang; Onur Eskiocak; David G. Thanassi; Mark H. Kaplan et al.
Source: check_circle
Crossref

Comparative Analysis of Alternative Splicing Profiles in Th Cell Subsets Reveals Extensive Cell Type–Specific Effects Modulated by a Network of Transcription Factors and RNA-Binding Proteins

ImmunoHorizons
2021-09-01 | Journal article
Contributors: Quoseena Mir; Deepak K Lakshmipati; Benjamin J Ulrich; Mark H Kaplan; Sarath Chandra Janga
Source: check_circle
Crossref

Selectin Dependence of Allergic Skin Inflammation Is Diminished by Maternal Atopy

ImmunoHorizons
2021-08-01 | Journal article
Contributors: Ibrahim M Khan; Benjamin J Ulrich; Andrew S Nelson; Sarita Sehra; Geoffrey S Kansas; Mark H Kaplan
Source: check_circle
Crossref

Helminth‐induced regulation of T‐cell transfer colitis requires intact and regulated T cell Stat6 signaling in mice

European Journal of Immunology
2021-02 | Journal article
Contributors: Ahmed Metwali; Sarah Winckler; Joseph F. Urban, Jr; Mark H. Kaplan; M. Nedim Ince; David E. Elliott
Source: check_circle
Crossref

T follicular regulatory cells and IL-10 promote food antigen–specific IgE

Journal of Clinical Investigation
2020-06-08 | Journal article
Contributors: Markus M. Xie; Qiang Chen; Hong Liu; Kai Yang; Byunghee Koh; Hao Wu; Soheila J. Maleki; Barry K. Hurlburt; Joan Cook-Mills; Mark H. Kaplan et al.
Source: check_circle
Crossref

Expression Efficiency of Multiple Il9 Reporter Alleles Is Determined by Cell Lineage

ImmunoHorizons
2020-05-01 | Journal article
Contributors: Rakshin Kharwadkar; Benjamin J Ulrich; Amina Abdul Qayum; Byunghee Koh; Paula Licona-Limón; Richard A Flavell; Mark H Kaplan
Source: check_circle
Crossref

Calcitriol Regulates the Differentiation of IL-9–Secreting Th9 Cells by Modulating the Transcription Factor PU.1

The Journal of Immunology
2020-03-01 | Journal article
Contributors: Shachi Pranjal Vyas; Arman Kunwar Hansda; Mark H Kaplan; Ritobrata Goswami
Source: check_circle
Crossref

ResTORing barrier function in the skin

Journal of Allergy and Clinical Immunology
2020-01 | Journal article
Contributors: Jocelyn Wang; Mark H. Kaplan; Kai Yang
Source: check_circle
Crossref

BATF-Interacting Proteins Dictate Specificity in Th Subset Activity

The Journal of Immunology
2019-10-01 | Journal article
Contributors: Yongyao Fu; Byunghee Koh; Makoto Kuwahara; Benjamin J Ulrich; Rakshin Kharwadkar; Masakatsu Yamashita; Mark H Kaplan
Source: check_circle
Crossref

The Il9 CNS-25 Regulatory Element Controls Mast Cell and Basophil IL-9 Production

The Journal of Immunology
2019-09-01 | Journal article
Contributors: Amina Abdul Qayum; Byunghee Koh; Rebecca K Martin; Blake T Kenworthy; Rakshin Kharwadkar; Yongyao Fu; Wenting Wu; Daniel H Conrad; Mark H Kaplan
Source: check_circle
Crossref

Covalent Heterobivalent Inhibitor Design for Inhibition of IgE-Dependent Penicillin Allergy in a Murine Model

The Journal of Immunology
2019-07-01 | Journal article
Contributors: Peter E Deak; Baksun Kim; Byunghee Koh; Amina Abdul Qayum; Tanyel Kiziltepe; Mark H Kaplan; Basar Bilgicer
Source: check_circle
Crossref

Roles of T Follicular Helper Cells and T Follicular Regulatory Cells in Autoantibody Production in IL-2–Deficient Mice

ImmunoHorizons
2019-07-01 | Journal article
Contributors: Markus M Xie; Hong Liu; Caleb Corn; Byung-Hee Koh; Mark H Kaplan; Matthew J Turner; Alexander L Dent
Source: check_circle
Crossref

Endonuclease and redox activities of human apurinic/apyrimidinic endonuclease 1 have distinctive and essential functions in IgA class switch recombination

Journal of Biological Chemistry
2019-03 | Journal article
Contributors: Barbara Frossi; Giulia Antoniali; Kefei Yu; Nahid Akhtar; Mark H. Kaplan; Mark R. Kelley; Gianluca Tell; Carlo E.M. Pucillo
Source: check_circle
Crossref

Opening the Black Box of Immunosuppression

The Journal of Immunology
2018-12-01 | Journal article
Contributors: Mark H Kaplan
Source: check_circle
Crossref

Platelet-Activating Factor–Induced Reduction in Contact Hypersensitivity Responses Is Mediated by Mast Cells via Cyclooxygenase-2–Dependent Mechanisms

The Journal of Immunology
2018-06-15 | Journal article
Contributors: Jesus A Ocana; Eric Romer; Ravi Sahu; Sven-Christian Pawelzik; Garret A FitzGerald; Mark H Kaplan; Jeffrey B Travers
Source: check_circle
Crossref

Mechanism for initiation of food allergy: Dependence on skin barrier mutations and environmental allergen costimulation

Journal of Allergy and Clinical Immunology
2018-05 | Journal article
Contributors: Matthew T. Walker; Jeremy E. Green; Ryan P. Ferrie; Ashley M. Queener; Mark H. Kaplan; Joan M. Cook-Mills
Source: check_circle
Crossref

Specifically differentiated T cell subset promotes tumor immunity over fatal immunity

Journal of Experimental Medicine
2017-12-04 | Journal article
Contributors: Abdulraouf Ramadan; Brad Griesenauer; Djamilatou Adom; Reuben Kapur; Helmut Hanenberg; Chen Liu; Mark H. Kaplan; Sophie Paczesny
Source: check_circle
Crossref

Poly‐ADP ribose polymerase‐14 limits severity of allergic skin disease

Immunology
2017-11 | Journal article
Contributors: Purna Krishnamurthy; Sonia Da‐Silva‐Arnold; Matthew J. Turner; Jeffrey B. Travers; Mark H. Kaplan
Source: check_circle
Crossref

STAT4 Regulates the CD8+ Regulatory T Cell/T Follicular Helper Cell Axis and Promotes Atherogenesis in Insulin-Resistant Ldlr−/− Mice

The Journal of Immunology
2017-11-15 | Journal article
Contributors: Parésa L Taghavie-Moghadam; Tayab C Waseem; Julian Hattler; Lindsey M Glenn; Anca D Dobrian; Mark H Kaplan; Yi Yang; Roza Nurieva; Jerry L Nadler; Elena V Galkina
Source: check_circle
Crossref

IRF4 Modulates CD8+ T Cell Sensitivity to IL-2 Family Cytokines

ImmunoHorizons
2017-08-01 | Journal article
Contributors: Su Huang; Yingjia Shen; Duy Pham; Li Jiang; Zheng Wang; Mark H Kaplan; Guangjun Zhang; Jie Sun
Source: check_circle
Crossref

Resolution of inflammation by interleukin-9-producing type 2 innate lymphoid cells

Nature Medicine
2017-07-17 | Journal article
Contributors: Simon Rauber; Markus Luber; Stefanie Weber; Lisa Maul; Alina Soare; Thomas Wohlfahrt; Neng-Yu Lin; Katharina Dietel; Aline Bozec; Martin Herrmann et al.
Source: check_circle
Crossref

Paracrine IL-2 Is Required for Optimal Type 2 Effector Cytokine Production

The Journal of Immunology
2017-06-01 | Journal article
Contributors: Matthew R Olson; Benjamin J Ulrich; Sarah A Hummel; Ibrahim Khan; Brice Meuris; Yesesri Cherukuri; Alexander L Dent; Sarath Chandra Janga; Mark H Kaplan
Source: check_circle
Crossref

STAT3 Activation Impairs the Stability of Th9 Cells

The Journal of Immunology
2017-03-15 | Journal article
Contributors: Benjamin J Ulrich; Felipe Fortino Verdan; Andrew N J McKenzie; Mark H Kaplan; Matthew R Olson
Source: check_circle
Crossref

Etv5 Regulates IL-10 Production in Th Cells

The Journal of Immunology
2017-03-01 | Journal article
Contributors: Byunghee Koh; Matthew M Hufford; Xin Sun; Mark H Kaplan
Source: check_circle
Crossref

The ETS Family Transcription Factors Etv5 and PU.1 Function in Parallel To Promote Th9 Cell Development

The Journal of Immunology
2016-09-15 | Journal article
Contributors: Byunghee Koh; Matthew M Hufford; Duy Pham; Matthew R Olson; Tong Wu; Rukhsana Jabeen; Xin Sun; Mark H Kaplan
Source: check_circle
Crossref

Mast Cells Regulate Epidermal Barrier Function and the Development of Allergic Skin Inflammation

Journal of Investigative Dermatology
2016-07 | Journal article
Contributors: Sarita Sehra; Ana P.M. Serezani; Jesus A. Ocaña; Jeffrey B. Travers; Mark H. Kaplan
Source: check_circle
Crossref

STAT3 Impairs STAT5 Activation in the Development of IL-9–Secreting T Cells

The Journal of Immunology
2016-04-15 | Journal article
Contributors: Matthew R Olson; Felipe Fortino Verdan; Matthew M Hufford; Alexander L Dent; Mark H Kaplan
Source: check_circle
Crossref

Altered STAT4 Isoform Expression in Patients with Inflammatory Bowel Disease

Inflammatory Bowel Diseases
2015 | Journal article
EID:

2-s2.0-84942246258

Contributors: Jabeen, R.; Miller, L.; Yao, W.; Gupta, S.; Steiner, S.; Kaplan, M.H.
Source: Self-asserted source
Mark Kaplan via Scopus - Elsevier
grade
Preferred source (of 2)‎

STAT4 deficiency reduces the development of atherosclerosis in mice

Atherosclerosis
2015 | Journal article
EID:

2-s2.0-84941763150

Contributors: Taghavie-Moghadam, P.L.; Gjurich, B.N.; Jabeen, R.; Krishnamurthy, P.; Kaplan, M.H.; Dobrian, A.D.; Nadler, J.L.; Galkina, E.V.
Source: Self-asserted source
Mark Kaplan via Scopus - Elsevier

PU.1 Expression in T Follicular Helper Cells Limits CD40L-Dependent Germinal Center B Cell Development

The Journal of Immunology
2015-10-15 | Journal article
Contributors: Olufolakemi Awe; Matthew M Hufford; Hao Wu; Duy Pham; Hua-Chen Chang; Rukhsana Jabeen; Alexander L Dent; Mark H Kaplan
Source: check_circle
Crossref

An Inhibitory Role for the Transcription Factor Stat3 in Controlling IL-4 and Bcl6 Expression in Follicular Helper T Cells

The Journal of Immunology
2015-09-01 | Journal article
Contributors: Hao Wu; Lin-Lin Xu; Paulla Teuscher; Hong Liu; Mark H Kaplan; Alexander L Dent
Source: check_circle
Crossref

TH9 cells are required for tissue mast cell accumulation during allergic inflammation

Journal of Allergy and Clinical Immunology
2015-08 | Journal article
Contributors: Sarita Sehra; Weiguo Yao; Evelyn T. Nguyen; Nicole L. Glosson-Byers; Nahid Akhtar; Baohua Zhou; Mark H. Kaplan
Source: Self-asserted source
Mark Kaplan via Crossref Metadata Search
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Peer review (32 reviews for 12 publications/grants)

Review activity for Cell reports. (2)
Review activity for eLife (1)
Review activity for Experimental and molecular medicine (1)
Review activity for Immunity. (1)
Review activity for JoVE. (1)
Review activity for Mucosal immunology. (1)
Review activity for Nature communications (2)
Review activity for Nature immunology. (3)
Review activity for Science advances. (1)
Review activity for Science translational medicine. (1)
Review activity for Science. (2)
Review activity for The journal of allergy and clinical immunology (16)