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Loop profile: 674062

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China

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Employment (1)

Huazhong University of Science and Technology Tongji Medical College: Wuhan, Hubei, CN

2010-07 to present | Professor/ Director of the Academic Affairs Office (Department of Pharmacy)
Employment
Source: Self-asserted source
Ming Xiang

Education and qualifications (3)

Medical College of Georgia: Georgia, AS

2010 to 2011 | visiting scholar (Department of Pharmacy)
Qualification
Source: Self-asserted source
Ming Xiang

Heidelberg University: Tiffin, OH, US

2004 to 2005 | visiting scholar (Department of Pharmacy)
Qualification
Source: Self-asserted source
Ming Xiang

University of Catania: Catania, IT

1997 to 1999 | visiting scholar (Department of Pharmacy)
Qualification
Source: Self-asserted source
Ming Xiang

Professional activities (2)

Chinese Pharmacological Society: Beijing, CN

2014 to present | director
Invited position
Source: Self-asserted source
Ming Xiang

Applied Pharmacology Committee of the Chinese Pharmaceutical Society: Beijing, CN

2014 to present | Membership
Service
Source: Self-asserted source
Ming Xiang

Funding (5)

CARD9调控DCs糖代谢重塑其功能介导胰腺癌发生发展的作用机制研究

2019-01 to 2022-12 | Grant
National Natural Science Foundation of China (Wuhan, CN)
GRANT_NUMBER:

81872000
Source: Self-asserted source
Ming Xiang

PID1基因介导胰岛素抵抗环境下肿瘤发生的机制及药物靶点研究

2017-01 to 2018-12 | Grant
National Natural Science Foundation of China (Wuhan , CN)
GRANT_NUMBER:

81673440
Source: Self-asserted source
Ming Xiang

当归六黄汤免疫调控胰岛素抵抗的作用机制及配伍研究

2015-01 to 2018-12 | Grant
National Natural Science Foundation of China (Wuhan, CN)
GRANT_NUMBER:

81473585
Source: Self-asserted source
Ming Xiang

新型mcDC负调控T细胞免疫耐受、干预β细胞再生的作用机制及药物靶点研究

2013-01 to 2016-12 | Grant
National Natural Science Foundation of China (Wuhan, CN)
GRANT_NUMBER:

91229144
Source: Self-asserted source
Ming Xiang

RegIII信号通路与SOCS3甲基化协同调控胰腺炎症恶性转化的分子机制研究

2013-01 to 2015-12 | Grant
National Natural Science Foundation of China (Wuhan, CN)
GRANT_NUMBER:

91229114
Source: Self-asserted source
Ming Xiang

Works (44)

SIRT1: Harnessing multiple pathways to hinder NAFLD.

Pharmacological research
2024-03-23 | Journal article
DOI: 10.1016/j.phrs.2024.107155
PMID: 38527697
Contributors: Tian C; Huang R; Xiang M
Source: Self-asserted source
Ming Xiang

Efficacy for Bone Deterioration in Mice with Osteoporosis and Pharmaceutical Properties of a Novel Compound Calcium Carbonate Granule

Journal of Food Biochemistry
2023-06-15 | Journal article
DOI: 10.1155/2023/5553926
Contributors: Kun Ma; Jialuo He; Huimin Yuan; Jiayu He; Ming Xiang; Jae Young Je
Source: check_circle
Crossref

Obesity contributes to hepatocellular carcinoma development via immunosuppressive microenvironment remodeling.

Frontiers in immunology
2023-05-17 | Review
DOI: 10.3389/fimmu.2023.1166440
PMID: 37266440
PMC: PMC10231659
Contributors: Yang J; He J; Feng Y; Xiang M
Source: Self-asserted source
Ming Xiang

Dual role of PID1 in regulating apoptosis induced by distinct anticancer-agents through AKT/Raf-1-dependent pathway in hepatocellular carcinoma

Cell Death Discovery
2023-04-28 | Journal article
DOI: 10.1038/s41420-023-01405-1
Contributors: Jian Yang; Senlin Li; Jialuo He; Qianqian Xu; Mengyuan Xie; Ci Yang; Hongjie Wang; Yonghui Zhang; Qian Wan; Ming Xiang
Source: check_circle
Crossref

CARD9 deficiency promotes pancreatic cancer growth by blocking dendritic cell maturation via SLC6A8-mediated creatine transport.

Oncoimmunology
2023-04-19 | Journal article | Author
DOI: 10.1080/2162402x.2023.2204015
PMID: 37089447
PMC: PMC10120541
Contributors: Cheng Tian; Yuan H; Lu Y; He H; Li Q; Li S; Yang J; Wang M; Xu R; Liu Q et al.
Source: Self-asserted source
Ming Xiang

Pancreatic sympathetic innervation disturbance in type 1 diabetes.

Clinical immunology (Orlando, Fla.)
2023-04-05 | Journal article
DOI: 10.1016/j.clim.2023.109319
PMID: 37024024
Contributors: Li S; Yuan H; Yang K; Li Q; Xiang M
Source: Self-asserted source
Ming Xiang

The combination of gemcitabine and ginsenoside Rh2 enhances the immune function of dendritic cells against pancreatic cancer via the CARD9-BCL10-MALT1 / NF-κB pathway.

Clinical immunology (Orlando, Fla.)
2022-12-26 | Journal article
DOI: 10.1016/j.clim.2022.109217
PMID: 36581220
Contributors: Li Q; He J; Li S; Tian C; Yang J; Yuan H; Lu Y; Fagone P; Nicoletti F; Xiang M
Source: Self-asserted source
Ming Xiang

Regenerating islet-derived protein 3 gamma (Reg3g) ameliorates tacrolimus-induced pancreatic β-cell dysfunction in mice by restoring mitochondrial function.

British journal of pharmacology
2022-02-22 | Journal article
DOI: 10.1111/bph.15803
PMID: 35060126
Contributors: Senlin li; Zhou H; Xie M; Zhang Z; Gou J; Yang J; Tian C; Ma K; Wang CY; Lu Y et al.
Source: Self-asserted source
Ming Xiang

Kinsenoside attenuates liver fibro-inflammation by suppressing dendritic cells via the PI3K-AKT-FoxO1 pathway.

Pharmacological research
2022-01-21 | Journal article
DOI: 10.1016/j.phrs.2022.106092
PMID: 35066108
PMC: PMC8776354
Contributors: Xiang M; Liu T; Tian C; Ma K; Gou J; Huang R; Li S; Li Q; Xu C; Li L et al.
Source: Self-asserted source
Ming Xiang

Therapeutic Agents Against COVID-19 with Clinical Evidence

Current Pharmaceutical Design
2021-04 | Journal article
DOI: 10.2174/1381612827666210114150951
Contributors: Cheng Tian; Ming Xiang
Source: check_circle
Crossref

Anti-inflammatory and metabolic reprogramming effects of MENK produce antitumor response in CT26 tumor-bearing mice.

Journal of leukocyte biology
2020-01-29 | Journal article
DOI: 10.1002/jlb.3ma0120-578r
PMID: 31994797
Source: Self-asserted source
Ming Xiang
grade
Preferred source (of 2)‎

Ginsenoside Rh2 reverses cyclophosphamide-induced immune deficiency by regulating fatty acid metabolism.

Journal of leukocyte biology
2019-06-18 | Journal article
DOI: 10.1002/jlb.2a0419-117r
PMID: 31211478
Contributors: Qian Y; Huang R; Li S; Xie R; Qian B; Zhang Z; Li L; Wang B; Tian C; Yang J et al.
Source: Self-asserted source
Ming Xiang

Exploring the protective effect of ShengMai-Yin and Ganmaidazao decoction combination against type 2 diabetes mellitus with nonalcoholic fatty liver disease by network pharmacology and validation in KKAy mice.

Journal of ethnopharmacology
2019-06-16 | Journal article
DOI: 10.1016/j.jep.2019.112029
PMID: 31216433
Contributors: Li S; Qian Y; Xie R; Li Y; Jia Z; Zhang Z; Huang R; Tuo L; Quan Y; Yu Z et al.
Source: Self-asserted source
Ming Xiang

Epigenetically modulated FOXM1 suppresses dendritic cell maturation in pancreatic cancer and colon cancer.

Molecular oncology
2019-02-15 | Journal article
DOI: 10.1002/1878-0261.12443
PMID: 30628173
PMC: PMC6441919
Source: Self-asserted source
Ming Xiang

mTOR: A double-edged sword for diabetes.

Journal of leukocyte biology
2018-03-26 | Journal article
DOI: 10.1002/jlb.3mr0317-095rr
PMID: 29578634
Source: Self-asserted source
Ming Xiang

Exploring the Mechanism of Dangguiliuhuang Decoction Against Hepatic Fibrosis by Network Pharmacology and Experimental Validation.

Frontiers in Pharmacology
2018-03-05 | Journal article
DOI: 10.3389/fphar.2018.00187
PMID: 29556199
PMC: PMC5844928
Source: Self-asserted source
Ming Xiang

Immune and Metabolic Regulation Mechanism of Dangguiliuhuang Decoction against Insulin Resistance and Hepatic Steatosis.

Frontiers in pharmacology
2017-07-07 | Journal article
DOI: 10.3389/fphar.2017.00445
PMID: 28736524
PMC: PMC5500616
Source: Self-asserted source
Ming Xiang

Effects of kinsenoside, a potential immunosuppressive drug for autoimmune hepatitis, on dendritic cells/CD8+ T cells communication in mice.

Hepatology (Baltimore, Md.)
2016-10-28 | Journal article
DOI: 10.1002/hep.28825
PMID: 27639182
Source: Self-asserted source
Ming Xiang

Reg3g overexpression promotes β cell regeneration and induces immune tolerance in nonobese-diabetic mouse model.

Journal of leukocyte biology
2015-12-14 | Journal article
DOI: 10.1189/jlb.3a0815-371rrr
PMID: 26667474
Source: Self-asserted source
Ming Xiang

TAK1 inhibition prevents the development of autoimmune diabetes in NOD mice.

Scientific reports
2015-10-13 | Journal article
DOI: 10.1038/srep14593
PMID: 26459028
PMC: PMC4602205
Source: Self-asserted source
Ming Xiang
grade
Preferred source (of 2)‎

Protective Effects of the Total Coumarin Fraction of Urtica dentata on Experimental Diabetic Nephropathy In Vitro and In Vivo.

Planta medica
2015-09-14 | Journal article
DOI: 10.1055/s-0035-1557866
PMID: 26366750
Source: Self-asserted source
Ming Xiang
grade
Preferred source (of 2)‎

Interaction of dendritic cells and T lymphocytes for the therapeutic effect of Dangguiliuhuang decoction to autoimmune diabetes.

Scientific reports
2015-09-11 | Journal article
DOI: 10.1038/srep13982
PMID: 26358493
PMC: PMC4566122
Source: Self-asserted source
Ming Xiang

Reg3g Promotes Pancreatic Carcinogenesis in a Murine Model of Chronic Pancreatitis.

Digestive diseases and sciences
2015-07-17 | Journal article
DOI: 10.1007/s10620-015-3787-5
PMID: 26182900
Source: Self-asserted source
Ming Xiang

Multiple mechanisms involved in diabetes protection by lipopolysaccharide in non-obese diabetic mice.

Toxicology and applied pharmacology
2015-04-17 | Journal article
DOI: 10.1016/j.taap.2015.04.006
PMID: 25896969
Source: Self-asserted source
Ming Xiang
grade
Preferred source (of 6)‎

SOCS3 methylation in synergy with Reg3A overexpression promotes cell growth in pancreatic cancer.

Journal of molecular medicine (Berlin, Germany)
2014-07-05 | Journal article
DOI: 10.1007/s00109-014-1184-8
PMID: 24996521
Source: Self-asserted source
Ming Xiang

Identification and quantification of total coumarins from Urtica dentata Hand and its roles in promoting immune tolerance via TLR4-mediated dendritic cell immaturation.

Bioscience, biotechnology, and biochemistry
2013-06-07 | Journal article
DOI: 10.1271/bbb.120958
PMID: 23748786
Source: Self-asserted source
Ming Xiang

Targeting potassium channels Kv1.3 and KC a 3.1: routes to selective immunomodulators in autoimmune disorder treatment?

Pharmacotherapy
2013-04-05 | Journal article
DOI: 10.1002/phar.1236
PMID: 23649812
Source: Self-asserted source
Ming Xiang

Total coumarins from Urtica dentata Hand prevent murine autoimmune diabetes via suppression of the TLR4-signaling pathways.

Journal of ethnopharmacology
2013-01-20 | Journal article
DOI: 10.1016/j.jep.2013.01.009
PMID: 23340441
Source: Self-asserted source
Ming Xiang
grade
Preferred source (of 2)‎

Identification of a new specific Kv1.3 channel blocker, Ctri9577, from the scorpion Chaerilus tricostatus.

Peptides
2012-05-08 | Journal article
DOI: 10.1016/j.peptides.2012.04.023
PMID: 22580271
Source: Self-asserted source
Ming Xiang

The soybean peptide aglycin regulates glucose homeostasis in type 2 diabetic mice via IR/IRS1 pathway.

The Journal of nutritional biochemistry
2012-01-25 | Journal article
DOI: 10.1016/j.jnutbio.2011.09.007
PMID: 22278080
Source: Self-asserted source
Ming Xiang

Antilithic effects of extracts from Urtica dentata hand on calcium oxalate urinary stones in rats.

Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban
2011-10-25 | Journal article
DOI: 10.1007/s11596-011-0580-3
PMID: 22038359
Source: Self-asserted source
Ming Xiang

Therapeutic effects of total coumarins from Urtica dentata Hand on collagen-induced arthritis in Balb/c mice.

Journal of ethnopharmacology
2011-10-01 | Journal article
DOI: 10.1016/j.jep.2011.09.050
PMID: 22001857
Source: Self-asserted source
Ming Xiang

Intramuscular delivery of a naked DNA plasmid encoding proinsulin and pancreatic regenerating III protein ameliorates type 1 diabetes mellitus.

Pharmacological research
2010-12-24 | Journal article
DOI: 10.1016/j.phrs.2010.12.009
PMID: 21185938
Source: Self-asserted source
Ming Xiang

Immunosuppressive constituents from Urtica dentata Hand.

Journal of Asian natural products research
2010-08-01 | Journal article
DOI: 10.1080/10286020.2010.490779
PMID: 20706909
Source: Self-asserted source
Ming Xiang

Immunosuppressive effects of an ethyl acetate extract from Urtica dentata Hand on skin allograft rejection.

Journal of ethnopharmacology
2009-08-19 | Journal article
DOI: 10.1016/j.jep.2009.08.011
PMID: 19698774
Source: Self-asserted source
Ming Xiang

Prevention of type 1 diabetes by immature dendritic cells treated with an ethanol extract of Paecilomyces hepiali Chen mycelium.

Methods and findings in experimental and clinical pharmacology
2008-07-01 | Journal article
DOI: 10.1358/mf.2008.30.6.1186083
PMID: 18850043
Source: Self-asserted source
Ming Xiang

Diabetogenic T cells induce autoimmune diabetes in BALB/c mice.

Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih
2008-06-01 | Journal article
DOI: 10.1016/s1001-9294(09)60018-3
PMID: 18686627
Source: Self-asserted source
Ming Xiang

Insulin administration confers diabetes-preventive properties to NOD mice derived dendritic cells.

Immunopharmacology and immunotoxicology
2007-01-01 | Journal article
DOI: 10.1080/08923970701692973
PMID: 18075857
Source: Self-asserted source
Ming Xiang

Induction of antigen-specific immune responses in vivo after vaccination with dendritic cells transduced with adenoviral vectors encoding hepatitis C virus NS3.

Viral immunology
2006-01-01 | Journal article
DOI: 10.1089/vim.2006.19.210
PMID: 16817764
Source: Self-asserted source
Ming Xiang

Essential pathogenetic role for interferon (IFN-)gamma in concanavalin A-induced T cell-dependent hepatitis: exacerbation by exogenous IFN-gamma and prevention by IFN-gamma receptor-immunoglobulin fusion protein.

Cytokine
2000-04-01 | Journal article
DOI: 10.1006/cyto.1999.0561
PMID: 10805211
Source: Self-asserted source
Ming Xiang

Dichotomic effects of IFN-gamma on the development of systemic lupus erythematosus-like syndrome in MRL-lpr / lpr mice.

European journal of immunology
2000-02-01 | Journal article
DOI: 10.1002/1521-4141(200002)30:2<438::aid-immu438>3.3.co;2-4
PMID: 10671199
Source: Self-asserted source
Ming Xiang

Concanavalin A-induced hepatitis in mice is prevented by interleukin (IL)-10 and exacerbated by endogenous IL-10 deficiency.

Autoimmunity
1999-10-01 | Journal article
DOI: 10.3109/08916939908994050
PMID: 10680745
Source: Self-asserted source
Ming Xiang

Prevention by rolipram of concanavalin A-induced T-cell-dependent hepatitis in mice.

European journal of pharmacology
1999-02-01 | Journal article
DOI: 10.1016/s0014-2999(98)00901-7
PMID: 10079016
Source: Self-asserted source
Ming Xiang

Failure of exogenously administered interferon-gamma or blockage of endogenous interleukin-4 with specific inhibitors to augment the incidence of autoimmune diabetes in male NOD mice.

Autoimmunity
1999-01-01 | Journal article
DOI: 10.3109/08916939908994763
PMID: 10435719
Source: Self-asserted source
Ming Xiang

Peer review (18 reviews for 5 publications/grants)

Review activity for Biochimica et biophysica acta CR. (1)
Review activity for Current medical science. (1)
Review activity for Journal of Advanced Research (1)
Review activity for Journal of ethnopharmacology. (14)
Review activity for Materials today bio. (1)
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