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Activities

Employment (3)

University of North Carolina: Chapel Hill, NC, US

2022-10 to present | Research Associate (Center for Environmental Medicine, Asthma, and Lung Biology)
Employment
Source: Self-asserted source
Adam M Speen

Oak Ridge Institute for Science and Education: TN, TN, US

2018-11 to 2022-10 | Postdoctoral Fellow (Environmental Protection Agency)
Employment
Source: Self-asserted source
Adam M Speen

Charles River Laboratories International Inc: Wilmington, MA, US

2008-05-14 to 2010-09-03 | Sr. Laboratory Technician (Malvern, PA)
Employment
Source: Self-asserted source
Adam M Speen

Education and qualifications (3)

University of North Carolina at Chapel Hill: Chapel Hill, NC, US

2013-08-26 to 2018-05-11 | Ph.D. (Toxicology)
Education
Source: Self-asserted source
Adam M Speen

University of North Carolina at Greensboro: Greensboro, NC, US

2011-08-23 to 2013-05-13 | Master of Science (Biology)
Education
Source: Self-asserted source
Adam M Speen

Lehigh University: Bethlehem, PA, US

2003-08-27 to 2007-05-14 | Bachelor of Science (Biology)
Education
Source: Self-asserted source
Adam M Speen

Works (12)

Comparison of permeable cell culture inserts for use in culture of a human in vitro air–liquid interface model system

Physiological Reports
2024-02 | Journal article
Part of ISSN: 2051-817X
Part of ISSN: 2051-817X
Contributors: Stephanie Brocke; Adam M. Speen; Syed Masood; Cameron P. Worden; Ilona Jaspers
Source: Self-asserted source
Adam M Speen

Benchmark Dose Modeling Approaches for Volatile Organic Chemicals Using a Novel Air-Liquid Interface In Vitro Exposure System

Toxicological Sciences
2022-06-28 | Journal article
Contributors: Adam M Speen; Jessica R Murray; Quentin Todd Krantz; David Davies; Paul Evansky; Joshua A Harrill; Logan J Everett; Joseph L Bundy; Lisa A Dailey; Jazzlyn Hill et al.
Source: check_circle
Crossref

Oxysterols Modify NLRP2 in Epithelial Cells, Identifying a Mediator of Ozone-induced Inflammation

American Journal of Respiratory Cell and Molecular Biology
2021-11 | Journal article
Part of ISSN: 1044-1549
Part of ISSN: 1535-4989
Contributors: Alexia Perryman; Adam M. Speen; Hye-Young H. Kim; Jessica R. Hoffman; Phillip W. Clapp; William Rivera Martin; John N. Snouwaert; Beverly H. Koller; Ned A. Porter; Ilona Jaspers
Source: Self-asserted source
Adam M Speen

Electronic-Cigarette Use Alters Nasal Mucosal Immune Response to Live-attenuated Influenza Virus. A Clinical Trial

American Journal of Respiratory Cell and Molecular Biology
2021-01 | Journal article
Part of ISSN: 1044-1549
Part of ISSN: 1535-4989
Contributors: Meghan Rebuli; Ellen Glista-Baker; Jessica R. Hoffman; Parker F. Duffney; Carole Robinette; Adam M. Speen; Erica A. Pawlak; Radhika Dhingra; Terry L. Noah; Ilona Jaspers
Source: Self-asserted source
Adam M Speen

Small Molecule Antipsychotic Aripiprazole Potentiates Ozone-Induced Inflammation in Airway Epithelium

Chemical Research in Toxicology
2019-10-21 | Journal article
Contributors: Adam M. Speen; Jessica R. Hoffman; Hye-Young H. Kim; Yael N. Escobar; Grace E. Nipp; Meghan E. Rebuli; Ned A. Porter; Ilona Jaspers
Source: check_circle
Crossref

Wood Smoke Exposure Alters Human Inflammatory Responses to Viral Infection in a Sex-Specific Manner. A Randomized, Placebo-controlled Study

American Journal of Respiratory and Critical Care Medicine
2019-04-15 | Journal article
Part of ISSN: 1073-449X
Part of ISSN: 1535-4970
Contributors: Meghan E. Rebuli; Adam M. Speen; Elizabeth M. Martin; Kezia A. Addo; Erica A. Pawlak; Ellen Glista-Baker; Carole Robinette; Haibo Zhou; Terry L. Noah; Ilona Jaspers
Source: Self-asserted source
Adam M Speen

Macrophages from the upper and lower human respiratory tract are metabolically distinct

American Journal of Physiology-Lung Cellular and Molecular Physiology
2018-11-01 | Journal article
Part of ISSN: 1040-0605
Part of ISSN: 1522-1504
Contributors: Katelyn S. Lavrich; Adam M. Speen; Andrew J. Ghio; Philip A. Bromberg; James M. Samet; Neil E. Alexis
Source: Self-asserted source
Adam M Speen

Novel applications for a noninvasive sampling method of the nasal mucosa

American Journal of Physiology-Lung Cellular and Molecular Physiology
2017-02-01 | Journal article
Part of ISSN: 1040-0605
Part of ISSN: 1522-1504
Contributors: Meghan E. Rebuli; Adam M. Speen; Phillip W. Clapp; Ilona Jaspers
Source: Self-asserted source
Adam M Speen

Ozone-derived Oxysterols Affect Liver X Receptor (LXR) Signaling

Journal of Biological Chemistry
2016-11-25 | Journal article
Contributors: Adam M. Speen; Hye-Young H. Kim; Rebecca N. Bauer; Megan Meyer; Kymberly M. Gowdy; Michael B. Fessler; Kelly E. Duncan; Wei Liu; Ned A. Porter; Ilona Jaspers
Source: check_circle
Crossref

Mechanisms of CDDO-imidazolide-mediated cytoprotection against acrolein-induced neurocytotoxicity in SH-SY5Y cells and primary human astrocytes

Toxicology Letters
2015-10 | Journal article
Part of ISSN: 0378-4274
Contributors: Adam Speen; Colton Jones; Ruby Patel; Halley Shah; Palanisamy Nallasamy; Elizabeth A.S. Brooke; Hong Zhu; Y. Robert Li; Zhenquan Jia
Source: Self-asserted source
Adam M Speen

Protection of HepG2 cells against acrolein toxicity by 2-cyano-3,12-dioxooleana-1,9-dien-28-imidazolide via glutathione-mediated mechanism

Experimental Biology and Medicine
2015-10 | Journal article
Part of ISSN: 1535-3702
Part of ISSN: 1535-3699
Contributors: Halley Shah; Adam M Speen; Christina Saunders; Elizabeth AS Brooke; Palanisamy Nallasamy; Hong Zhu; Y Robert Li; Zhenquan Jia
Source: Self-asserted source
Adam M Speen

Role of H2O2 in the oxidative effects of zinc exposure in human airway epithelial cells

Redox Biology
2014 | Journal article
Part of ISSN: 2213-2317
Contributors: Phillip A. Wages; Robert Silbajoris; Adam Speen; Luisa Brighton; Andres Henriquez; Haiyan Tong; Philip A. Bromberg; Steven O. Simmons; James M. Samet
Source: Self-asserted source
Adam M Speen

Peer review (3 reviews for 1 publication/grant)

Review activity for Particle and fibre toxicology (3)