Personal information

United States

Activities

Employment (1)

Harvard Medical School: Boston, MA, US

2006 to present | Otto Krayer Professor of Systems Pharmacology (Systems Biology)
Employment
Source: Self-asserted source
Peter K Sorger

Education and qualifications (2)

University of Cambridge: Cambridge, Cambridgeshire, GB

1984 to 1997 | PhD (Laboratory of Molecular Biology)
Education
Source: Self-asserted source
Peter K Sorger

Harvard University: Cambridge, MA, US

1979 to 1984 | A.B. (Biochemistry)
Education
Source: Self-asserted source
Peter K Sorger

Professional activities (2)

Drug Information Association: Horsham, PA, US

Membership
Source: Self-asserted source
Peter K Sorger

American Association For Cancer Research: Philadelphia, Pennsylvania, US

Membership
Source: Self-asserted source
Peter K Sorger

Funding (13)

Pre-cancer atlases of cutaneous and hematologic origin (PATCH Center)

2018-09-30 to 2023-06-30 | Grant
National Cancer Institute (Rockville, US)
GRANT_NUMBER: U2CCA233262
Source: Self-asserted source
Peter K Sorger via DimensionsWizard

An Automated Scientific Discovery Framework (ASDF) for Mechanistic Reasoning Across Complex Data

2018-03-16 to 2022-03-15 | Grant
Defense Advanced Research Projects Agency (Arlington, US)
GRANT_NUMBER:

W911NF1810124

Source: Self-asserted source
Peter K Sorger via DimensionsWizard

Systems Pharmacology of Therapeutic and Adverse Responses to ImmuneCheckpoint and Small Molecule Drugs

2018-03-08 to 2023-02-28 | Grant
National Cancer Institute (Rockville, US)
GRANT_NUMBER: U54CA225088
Source: Self-asserted source
Peter K Sorger via DimensionsWizard

Harnessing Diverse BioInformatic Approaches to Repurpose Drugs for Alzheimer's Disease

Source: Self-asserted source
Peter K Sorger via DimensionsWizard

Illuminating Function of the Understudied Druggable Kinome

2017-09-15 to 2023-08-31 | Grant
National Institute of Diabetes and Digestive and Kidney Diseases (n/a, US)
GRANT_NUMBER: grant.U24DK116204
Source: Self-asserted source
Peter K Sorger via DimensionsWizard

Pharmaco Response Signatures and Disease Mechanism

2014-09-10 to 2020-06-30 | Grant
National Heart, Lung, and Blood Institute (Bethesda, US)
GRANT_NUMBER: 5U54HL127365-02
Source: Self-asserted source
Peter K Sorger via DimensionsWizard

Pharmaco Response Signatures and Disease Mechanism

2014-09-10 to 2020-06-30 | Grant
National Heart Lung and Blood Institute (n/a, US)
GRANT_NUMBER: grant.U54HL127365
Source: Self-asserted source
Peter K Sorger via DimensionsWizard

Pharmaco Response Signatures and Disease Mechanism

2014-09-10 to 2020-06-30 | Grant
National Heart Lung and Blood Institute (Bethesda, US)
GRANT_NUMBER: U54HL127365
Source: Self-asserted source
Peter K Sorger via DimensionsWizard

The HMS Laboratory of Systems Pharmacology

2014-09-01 to 2019-05-31 | Grant
National Institute of General Medical Sciences (Bethesda, US)
GRANT_NUMBER: 5P50GM107618-02
Source: Self-asserted source
Peter K Sorger via DimensionsWizard

Programmatic modeling for reasoning across complex mechanisms.

2014-07 to 2018-04 | Grant
Defense Advanced Research Projects Agency (VA, VA, US)
GRANT_NUMBER:

W911NF-14-1-0397

Source: Self-asserted source
Peter K Sorger

Pharmaco Response Signatures and Disease Mechanism

2010-09-27 to 2014-07-31 | Grant
National Human Genome Research Institute (n/a, US)
GRANT_NUMBER: grant.U54HG006097
Source: Self-asserted source
Peter K Sorger via DimensionsWizard

Pharmaco Response Signatures and Disease Mechanism

2010-09-27 to 2014-07-31 | Grant
National Human Genome Research Institute (Bethesda, US)
GRANT_NUMBER: U54HG006097
Source: Self-asserted source
Peter K Sorger via DimensionsWizard

Systems Biology of cell Decision Processes

2003-09-01 to 2014-08-31 | Grant
National Institute of General Medical Sciences (Bethesda, US)
GRANT_NUMBER: P50GM068762
Source: Self-asserted source
Peter K Sorger via DimensionsWizard

Works (50 of 303)

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Page 1 of 7

Dynamic Modeling of Cell Cycle Arrest Through Integrated Single-Cell and Mathematical Modelling Approaches

2025-02-26 | Preprint
Contributors: Javiera Cortés-Ríos; Maria Rodriguez-Fernandez; Peter K. Sorger; Fabian Fröhlich
Source: check_circle
Crossref

Cell2Cell: Explorative Cell Interaction Analysis in Multi-Volumetric Tissue Data

IEEE Transactions on Visualization and Computer Graphics
2025-01 | Journal article
Contributors: Eric Mörth; Kevin Sidak; Zoltan Maliga; Torsten Möller; Nils Gehlenborg; Peter Sorger; Hanspeter Pfister; Johanna Beyer; Robert Krüger
Source: check_circle
Crossref

Immune Profiling of Dermatologic Adverse Events from Checkpoint Blockade Using Tissue Cyclic Immunofluorescence: A Pilot Study

Journal of Investigative Dermatology
2024-08 | Journal article
Contributors: Zoltan Maliga; Daniel Y. Kim; Ai-Tram N. Bui; Jia-Ren Lin; Anna K. Dewan; Saagar Jadeja; George F. Murphy; Ajit J. Nirmal; Christine G. Lian; Peter K. Sorger et al.
Source: check_circle
Crossref

A CRISPRi/a screening platform to study cellular nutrient transport in diverse microenvironments

Nature Cell Biology
2024-05 | Journal article
Contributors: Christopher Chidley; Alicia M. Darnell; Benjamin L. Gaudio; Evan C. Lien; Anna M. Barbeau; Matthew G. Vander Heiden; Peter K. Sorger
Source: check_circle
Crossref

SCIMAP: A Python Toolkit for Integrated Spatial Analysis of Multiplexed Imaging Data

Journal of Open Source Software
2024-05-29 | Journal article
Contributors: Ajit J. Nirmal; Peter K. Sorger
Source: check_circle
Crossref

psudo: Exploring Multi-Channel Biomedical Image Data with Spatially and Perceptually Optimized Pseudocoloring

2024-04-15 | Preprint
Contributors: Simon Warchol; Jakob Troidl; Jeremy Muhlich; Robert Krueger; John Hoffer; Tica Lin; Johanna Beyer; Elena Glassman; Peter K. Sorger; Hanspeter Pfister
Source: check_circle
Crossref

Tribus: Semi-automated discovery of cell identities and phenotypes from multiplexed imaging and proteomic data

2024-03-14 | Preprint
Contributors: Ziqi Kang; Angela Szabo; Teodora Farago; Fernando Perez-Villatoro; Inga-Maria Launonen; Ella Anttila; Kevin Elias; Julia Casado; Peter Sorger; Anniina Färkkilä
Source: check_circle
Crossref

Systematic characterization of antibody–drug conjugate targets in central nervous system tumors

Neuro-Oncology
2024-03-04 | Journal article
Contributors: Shannon Coy; Jong Suk Lee; Sabrina J Chan; Terri Woo; Jacquelyn Jones; Sanda Alexandrescu; Patrick Y Wen; Peter K Sorger; Keith L Ligon; Sandro Santagata
Source: check_circle
Crossref

Tissue Cyclic Immunofluorescence (t-CyCIF)_PCA2024_spacer v1

2024-01-31 | Preprint
Contributors: Jia Ren Lin; Benjamin Izar; Yu-An Chen; Ziming Du; Shaolin Mei; Sandro Santagata; Peter Sorger
Source: check_circle
Crossref

Residency Octree: A Hybrid Approach for Scalable Web-Based Multi-Volume Rendering

IEEE Transactions on Visualization and Computer Graphics
2023 | Journal article
Contributors: Lukas Herzberger; Markus Hadwiger; Robert Krüger; Peter Sorger; Hanspeter Pfister; Eduard Gröller; Johanna Beyer
Source: check_circle
Crossref

Cell Spotter (CSPOT): A machine-learning approach to automated cell spotting and quantification of highly multiplexed tissue images

2023-11-17 | Preprint
Contributors: Ajit J. Nirmal; Clarence Yapp; Sandro Santagata; Peter K. Sorger
Source: check_circle
Crossref

Multiplexed 3D Analysis of Cell Plasticity and Immune Niches in Melanoma

2023-11-15 | Preprint
Contributors: Clarence Yapp; Ajit J. Nirmal; Felix Zhou; Zoltan Maliga; Paula Montero Llopis; George F Murphy; Christine G Lian; Gaudenz Danuser; Sandro Santagata; Peter K. Sorger
Source: check_circle
Crossref

A Hybrid Structure-Based Machine Learning Approach for Predicting Kinase Inhibition by Small Molecules

Journal of Chemical Information and Modeling
2023-09-11 | Journal article
Contributors: Changchang Liu; Peter Kutchukian; Nhan D. Nguyen; Mohammed AlQuraishi; Peter K. Sorger
Source: check_circle
Crossref

Automated assembly of molecular mechanisms at scale from text mining and curated databases

Molecular Systems Biology
2023-05-09 | Journal article
Contributors: John A Bachman; Benjamin M Gyori; Peter K Sorger
Source: check_circle
Crossref

Immune Profiling of Dermatologic Adverse Events from Checkpoint Blockade using Tissue Cyclic Immunofluorescence

2023-04-05 | Preprint
Contributors: Zoltan Maliga; Daniel Y. Kim; Ai-Tram N. Bui; Jia-Ren Lin; Anna K. Dewan; George F. Murphy; Ajit J. Nirmal; Christine G. Lian; Peter K. Sorger; Nicole R. LeBoeuf
Source: check_circle
Crossref

Data from Independent Drug Action in Combination Therapy: Implications for Precision Oncology

2023-04-04 | Preprint
Contributors: Deborah Plana; Adam C. Palmer; Peter K. Sorger
Source: check_circle
Crossref

Data from Independent Drug Action in Combination Therapy: Implications for Precision Oncology

2023-04-04 | Preprint
Contributors: Deborah Plana; Adam C. Palmer; Peter K. Sorger
Source: check_circle
Crossref

Supplementary Data from Independent Drug Action in Combination Therapy: Implications for Precision Oncology

2023-04-04 | Preprint
Contributors: Deborah Plana; Adam C. Palmer; Peter K. Sorger
Source: check_circle
Crossref

Supplementary Data from Independent Drug Action in Combination Therapy: Implications for Precision Oncology

2023-04-04 | Preprint
Contributors: Deborah Plana; Adam C. Palmer; Peter K. Sorger
Source: check_circle
Crossref

Data from HAND1 and BARX1 Act as Transcriptional and Anatomic Determinants of Malignancy in Gastrointestinal Stromal Tumor

2023-03-31 | Preprint
Contributors: Matthew L. Hemming; Shannon Coy; Jia-Ren Lin; Jessica L. Andersen; Joanna Przybyl; Emanuele Mazzola; Amr H. Abdelhamid Ahmed; Matt van de Rijn; Peter K. Sorger; Scott A. Armstrong et al.
Source: check_circle
Crossref

Data from HAND1 and BARX1 Act as Transcriptional and Anatomic Determinants of Malignancy in Gastrointestinal Stromal Tumor

2023-03-31 | Preprint
Contributors: Matthew L. Hemming; Shannon Coy; Jia-Ren Lin; Jessica L. Andersen; Joanna Przybyl; Emanuele Mazzola; Amr H. Abdelhamid Ahmed; Matt van de Rijn; Peter K. Sorger; Scott A. Armstrong et al.
Source: check_circle
Crossref

Data from Predictable Clinical Benefits without Evidence of Synergy in Trials of Combination Therapies with Immune-Checkpoint Inhibitors

2023-03-31 | Preprint
Contributors: Adam C. Palmer; Benjamin Izar; Haeun Hwangbo; Peter K. Sorger
Source: check_circle
Crossref

Data from Predictable Clinical Benefits without Evidence of Synergy in Trials of Combination Therapies with Immune-Checkpoint Inhibitors

2023-03-31 | Preprint
Contributors: Adam C. Palmer; Benjamin Izar; Haeun Hwangbo; Peter K. Sorger
Source: check_circle
Crossref

Supplementary Data from HAND1 and BARX1 Act as Transcriptional and Anatomic Determinants of Malignancy in Gastrointestinal Stromal Tumor

2023-03-31 | Preprint
Contributors: Matthew L. Hemming; Shannon Coy; Jia-Ren Lin; Jessica L. Andersen; Joanna Przybyl; Emanuele Mazzola; Amr H. Abdelhamid Ahmed; Matt van de Rijn; Peter K. Sorger; Scott A. Armstrong et al.
Source: check_circle
Crossref

Supplementary Data from HAND1 and BARX1 Act as Transcriptional and Anatomic Determinants of Malignancy in Gastrointestinal Stromal Tumor

2023-03-31 | Preprint
Contributors: Matthew L. Hemming; Shannon Coy; Jia-Ren Lin; Jessica L. Andersen; Joanna Przybyl; Emanuele Mazzola; Amr H. Abdelhamid Ahmed; Matt van de Rijn; Peter K. Sorger; Scott A. Armstrong et al.
Source: check_circle
Crossref

Supplementary Data from Predictable Clinical Benefits without Evidence of Synergy in Trials of Combination Therapies with Immune-Checkpoint Inhibitors

2023-03-31 | Preprint
Contributors: Adam C. Palmer; Benjamin Izar; Haeun Hwangbo; Peter K. Sorger
Source: check_circle
Crossref

Supplementary Data from Predictable Clinical Benefits without Evidence of Synergy in Trials of Combination Therapies with Immune-Checkpoint Inhibitors

2023-03-31 | Preprint
Contributors: Adam C. Palmer; Benjamin Izar; Haeun Hwangbo; Peter K. Sorger
Source: check_circle
Crossref

Supplementary Figure from Predictable Clinical Benefits without Evidence of Synergy in Trials of Combination Therapies with Immune-Checkpoint Inhibitors

2023-03-31 | Preprint
Contributors: Adam C. Palmer; Benjamin Izar; Haeun Hwangbo; Peter K. Sorger
Source: check_circle
Crossref

Supplementary Figure from Predictable Clinical Benefits without Evidence of Synergy in Trials of Combination Therapies with Immune-Checkpoint Inhibitors

2023-03-31 | Preprint
Contributors: Adam C. Palmer; Benjamin Izar; Haeun Hwangbo; Peter K. Sorger
Source: check_circle
Crossref

Supplementary Table from Predictable Clinical Benefits without Evidence of Synergy in Trials of Combination Therapies with Immune-Checkpoint Inhibitors

2023-03-31 | Preprint
Contributors: Adam C. Palmer; Benjamin Izar; Haeun Hwangbo; Peter K. Sorger
Source: check_circle
Crossref

Supplementary Table from Predictable Clinical Benefits without Evidence of Synergy in Trials of Combination Therapies with Immune-Checkpoint Inhibitors

2023-03-31 | Preprint
Contributors: Adam C. Palmer; Benjamin Izar; Haeun Hwangbo; Peter K. Sorger
Source: check_circle
Crossref

Table S1 from HAND1 and BARX1 Act as Transcriptional and Anatomic Determinants of Malignancy in Gastrointestinal Stromal Tumor

2023-03-31 | Preprint
Contributors: Matthew L. Hemming; Shannon Coy; Jia-Ren Lin; Jessica L. Andersen; Joanna Przybyl; Emanuele Mazzola; Amr H. Abdelhamid Ahmed; Matt van de Rijn; Peter K. Sorger; Scott A. Armstrong et al.
Source: check_circle
Crossref

Table S1 from HAND1 and BARX1 Act as Transcriptional and Anatomic Determinants of Malignancy in Gastrointestinal Stromal Tumor

2023-03-31 | Preprint
Contributors: Matthew L. Hemming; Shannon Coy; Jia-Ren Lin; Jessica L. Andersen; Joanna Przybyl; Emanuele Mazzola; Amr H. Abdelhamid Ahmed; Matt van de Rijn; Peter K. Sorger; Scott A. Armstrong et al.
Source: check_circle
Crossref

Table S2 from HAND1 and BARX1 Act as Transcriptional and Anatomic Determinants of Malignancy in Gastrointestinal Stromal Tumor

2023-03-31 | Preprint
Contributors: Matthew L. Hemming; Shannon Coy; Jia-Ren Lin; Jessica L. Andersen; Joanna Przybyl; Emanuele Mazzola; Amr H. Abdelhamid Ahmed; Matt van de Rijn; Peter K. Sorger; Scott A. Armstrong et al.
Source: check_circle
Crossref

Table S2 from HAND1 and BARX1 Act as Transcriptional and Anatomic Determinants of Malignancy in Gastrointestinal Stromal Tumor

2023-03-31 | Preprint
Contributors: Matthew L. Hemming; Shannon Coy; Jia-Ren Lin; Jessica L. Andersen; Joanna Przybyl; Emanuele Mazzola; Amr H. Abdelhamid Ahmed; Matt van de Rijn; Peter K. Sorger; Scott A. Armstrong et al.
Source: check_circle
Crossref

Table S3 from HAND1 and BARX1 Act as Transcriptional and Anatomic Determinants of Malignancy in Gastrointestinal Stromal Tumor

2023-03-31 | Preprint
Contributors: Matthew L. Hemming; Shannon Coy; Jia-Ren Lin; Jessica L. Andersen; Joanna Przybyl; Emanuele Mazzola; Amr H. Abdelhamid Ahmed; Matt van de Rijn; Peter K. Sorger; Scott A. Armstrong et al.
Source: check_circle
Crossref

Table S3 from HAND1 and BARX1 Act as Transcriptional and Anatomic Determinants of Malignancy in Gastrointestinal Stromal Tumor

2023-03-31 | Preprint
Contributors: Matthew L. Hemming; Shannon Coy; Jia-Ren Lin; Jessica L. Andersen; Joanna Przybyl; Emanuele Mazzola; Amr H. Abdelhamid Ahmed; Matt van de Rijn; Peter K. Sorger; Scott A. Armstrong et al.
Source: check_circle
Crossref

Table S4 from HAND1 and BARX1 Act as Transcriptional and Anatomic Determinants of Malignancy in Gastrointestinal Stromal Tumor

2023-03-31 | Preprint
Contributors: Matthew L. Hemming; Shannon Coy; Jia-Ren Lin; Jessica L. Andersen; Joanna Przybyl; Emanuele Mazzola; Amr H. Abdelhamid Ahmed; Matt van de Rijn; Peter K. Sorger; Scott A. Armstrong et al.
Source: check_circle
Crossref

Table S4 from HAND1 and BARX1 Act as Transcriptional and Anatomic Determinants of Malignancy in Gastrointestinal Stromal Tumor

2023-03-31 | Preprint
Contributors: Matthew L. Hemming; Shannon Coy; Jia-Ren Lin; Jessica L. Andersen; Joanna Przybyl; Emanuele Mazzola; Amr H. Abdelhamid Ahmed; Matt van de Rijn; Peter K. Sorger; Scott A. Armstrong et al.
Source: check_circle
Crossref

Table S5 from HAND1 and BARX1 Act as Transcriptional and Anatomic Determinants of Malignancy in Gastrointestinal Stromal Tumor

2023-03-31 | Preprint
Contributors: Matthew L. Hemming; Shannon Coy; Jia-Ren Lin; Jessica L. Andersen; Joanna Przybyl; Emanuele Mazzola; Amr H. Abdelhamid Ahmed; Matt van de Rijn; Peter K. Sorger; Scott A. Armstrong et al.
Source: check_circle
Crossref

Table S5 from HAND1 and BARX1 Act as Transcriptional and Anatomic Determinants of Malignancy in Gastrointestinal Stromal Tumor

2023-03-31 | Preprint
Contributors: Matthew L. Hemming; Shannon Coy; Jia-Ren Lin; Jessica L. Andersen; Joanna Przybyl; Emanuele Mazzola; Amr H. Abdelhamid Ahmed; Matt van de Rijn; Peter K. Sorger; Scott A. Armstrong et al.
Source: check_circle
Crossref

Table S6 from HAND1 and BARX1 Act as Transcriptional and Anatomic Determinants of Malignancy in Gastrointestinal Stromal Tumor

2023-03-31 | Preprint
Contributors: Matthew L. Hemming; Shannon Coy; Jia-Ren Lin; Jessica L. Andersen; Joanna Przybyl; Emanuele Mazzola; Amr H. Abdelhamid Ahmed; Matt van de Rijn; Peter K. Sorger; Scott A. Armstrong et al.
Source: check_circle
Crossref

Table S6 from HAND1 and BARX1 Act as Transcriptional and Anatomic Determinants of Malignancy in Gastrointestinal Stromal Tumor

2023-03-31 | Preprint
Contributors: Matthew L. Hemming; Shannon Coy; Jia-Ren Lin; Jessica L. Andersen; Joanna Przybyl; Emanuele Mazzola; Amr H. Abdelhamid Ahmed; Matt van de Rijn; Peter K. Sorger; Scott A. Armstrong et al.
Source: check_circle
Crossref

Mechanistic model of MAPK signaling reveals how allostery and rewiring contribute to drug resistance

Molecular Systems Biology
2023-02-10 | Journal article
Contributors: Fabian Fröhlich; Luca Gerosa; Jeremy Muhlich; Peter K Sorger
Source: check_circle
Crossref

Nociceptor neuroimmune interactomes reveal cell type- and injury-specific inflammatory pain pathways

2023-02-03 | Preprint
Contributors: Aakanksha Jain; Benjamin M. Gyori; Sara Hakim; Samuel Bunga; Daniel G Taub; Mari Carmen Ruiz-Cantero; Candace Tong-Li; Nicholas Andrews; Peter K Sorger; Clifford J Woolf
Source: check_circle
Crossref

A CRISPRi/a screening platform to study cellular nutrient transport in diverse microenvironments

2023-01-26 | Preprint
Contributors: Christopher Chidley; Alicia M. Darnell; Benjamin L. Gaudio; Evan C. Lien; Anna M. Barbeau; Matthew G. Vander Heiden; Peter K. Sorger
Source: check_circle
Crossref

3D multiplexed tissue imaging reconstruction and optimized region-of-interest (ROI) selection through deep learning model of channels embedding

2022-12-12 | Preprint
Contributors: Erik Burlingame; Luke Ternes; Jia-Ren Lin; Yu-An Chen; Eun Na Kim; Joe W. Gray; Sandro Santagata; Peter K. Sorger; Young Hwan Chang
Source: check_circle
Crossref

Drug independence and the curability of cancer by combination chemotherapy

Trends in Cancer
2022-11 | Journal article
Contributors: Amy E. Pomeroy; Emmett V. Schmidt; Peter K. Sorger; Adam C. Palmer
Source: check_circle
Crossref

Tissue Cyclic Immunofluorescence (t-CyCIF) version 3

protocols.io
2022-10-18 | Journal article | Author
Contributors: Jia-Ren Lin; Yu-An Chen; Sandro Santagata; Peter K Sorger
Source: check_circle
protocols.io

Paired evaluation defines performance landscapes for machine learning models

2022-09-12 | Preprint
Contributors: Maulik K. Nariya; Caitlin E. Mills; Peter K. Sorger; Artem Sokolov
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Crossref
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