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Loop profile: 97542

Keywords

T cell - MHC - tuberculosis - trogocytosis

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Employment (8)

IPBS/CNRS/Université Paul Sabatier: Toulouse, Midi-Pyrénées, FR

2011-09 to present | Professor in Immunology
Employment
Source: Self-asserted source
Denis Hudrisier

IPBS/CNRS/Université Paul Sabatier: Toulouse, Midi-Pyrénées, FR

2004-09 to 2011-09 | Associate Professor in immunloogy
Employment
Source: Self-asserted source
Denis Hudrisier

CPTP/INSERM/Université Paul Sabatier: Toulouse, Midi-Pyrénées, FR

1999-09 to 2004-09 | Associate Professor in Immunology
Employment
Source: Self-asserted source
Denis Hudrisier

Institut de Pharmacologie et de Biologie Structurale: Toulouse, Midi-Pyrénées, FR

1998-10 to 1999-09 | Post-doctoral researcher
Employment
Source: Self-asserted source
Denis Hudrisier

Ludwig Institute for Cancer Research Lausanne Branch of Immunology: Epalinges, VD, CH

1996-09 to 1998-10 | Post-doctorala researcher
Employment
Source: Self-asserted source
Denis Hudrisier

Institut de Pharmacologie et de Biologie Structurale: Toulouse, Midi-Pyrénées, FR

1993-09 to 1996-07 | PhD student
Employment
Source: Self-asserted source
Denis Hudrisier

Institut de Pharmacologie et de Biologie Structurale: Toulouse, Midi-Pyrénées, FR

1992-09 to 1994-07 | DEA student
Employment
Source: Self-asserted source
Denis Hudrisier

Sanofi-Elf-BioRecherches: Labège, HG, FR

1989 to 1992 | Technician
Employment
Source: Self-asserted source
Denis Hudrisier

Education and qualifications (3)

Université Paul Sabatier: Toulouse, Midi-Pyrénées, FR

2004 to present | Habilitation à diriger des recherches (HDR)
Education
Source: Self-asserted source
Denis Hudrisier

Université Paul Sabatier: Toulouse, Midi-Pyrénées, FR

1996-07 | PhD
Education
Source: Self-asserted source
Denis Hudrisier

Université Paul Sabatier: Toulouse, Midi-Pyrénées, FR

1993-07 | Diplome d'études approfondies
Education
Source: Self-asserted source
Denis Hudrisier

Funding (5)

Immunova

2015 to 2016 | Grant
IDEX, Toulouse (Toulouse, FR)
Source: Self-asserted source
Denis Hudrisier

Implickers

2014 to 2015 | Grant
Université de Toulouse (Toulouse, FR)
Source: Self-asserted source
Denis Hudrisier

TRAPassays to monitor the anti-tuberculous immune response

2012 to 2014 | Contract
Merieux Research Grants (Lyon, FR)
Source: Self-asserted source
Denis Hudrisier

Role of trogocytosis on CD8 T cell infection by HIV-1

2007 to 2008 | Grant
Sidaction (Paris, FR)
Source: Self-asserted source
Denis Hudrisier

TRAP assays for the detection of immune responses induced by vaccines

2005 to 2007 | Grant
Region Midi-Pyréneés (Toulouse, FR)
Source: Self-asserted source
Denis Hudrisier

Works (50 of 52)

Items per page:
Page 1 of 2

Mycobacterial d-serine impairs TB control

Nature Immunology
2024-07 | Journal article
DOI: 10.1038/s41590-024-01873-2
Contributors: Maxime Caouaille; Denis Hudrisier; Olivier Neyrolles
Source: check_circle
Crossref

Metabolic regulation of ILC2 differentiation into ILC1-like cells during Mycobacterium tuberculosis infection

2021-01-19 | Preprint
DOI: 10.1101/2021.01.19.427257
Contributors: Dan Corral; Alison Charton; Maria Z Krauss; Eve Blanquart; Florence Levillain; Emma Lefrançais; Tamara Sneperger; Jean-Philippe Girard; Gérard Eberl; Yannick Poquet et al.
Source: check_circle
Crossref

C-type lectin receptor DCIR modulates immunity to tuberculosis by sustaining type I interferon signaling in dendritic cells.

Proceedings of the National Academy of Sciences of the United States of America
2017-01 | Journal article
DOI: 10.1073/pnas.1613254114
PMID: 28069953
PMC: PMC5278472
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

Wheeling and Dealing With Antigen Presentation in Tuberculosis.

Trends in microbiology
2016-03 | Journal article
DOI: 10.1016/j.tim.2016.01.001
PMID: 26794467
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

Collectin CL-LK Is a Novel Soluble Pattern Recognition Receptor for Mycobacterium tuberculosis.

2015 | Journal article
DOI: 10.1371/journal.pone.0132692
PMID: 26173080
PMC: PMC4501752
Contributors: Troegeler A; Lugo-Villarino G; Hansen S; Rasolofo V; Henriksen ML; Mori K; Ohtani K; Duval C; Mercier I; Bénard A et al.
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

Antigen smuggling in tuberculosis.

2014-06 | Journal article
DOI: 10.1016/j.chom.2014.05.018
PMID: 24922567
Contributors: Hudrisier D; Neyrolles O
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

Emerging trends in the formation and function of tuberculosis granulomas.

2012 | Journal article
DOI: 10.3389/fimmu.2012.00405
PMID: 23308074
PMC: PMC3538282
Contributors: Lugo-Villarino G; Hudrisier D; Benard A; Neyrolles O
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

C-type lectins with a sweet spot for Mycobacterium tuberculosis.

2011-03 | Journal article
DOI: 10.1556/EuJMI.1.2011.1.6
PMID: 24466434
PMC: PMC3894812
Contributors: Lugo-Villarino G; Hudrisier D; Tanne A; Neyrolles O
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

Could CD4 capture by CD8+ T cells play a role in HIV spreading?

2010 | Journal article
DOI: 10.1155/2010/907371
PMID: 20368790
PMC: PMC2846356
Contributors: Aucher A; Puigdomènech I; Joly E; Clotet B; Hudrisier D; Blanco J
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

Preferential transfer of certain plasma membrane proteins onto T and B cells by trogocytosis.

2010 | Journal article
DOI: 10.1371/journal.pone.0008716
PMID: 20090930
PMC: PMC2806835
Contributors: Daubeuf S; Aucher A; Bordier C; Salles A; Serre L; Gaibelet G; Faye JC; Favre G; Joly E; Hudrisier D
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

The direction of plasma membrane exchange between lymphocytes and accessory cells by trogocytosis is influenced by the nature of the accessory cell.

2010-02 | Journal article
DOI: 10.4049/jimmunol.0901570
PMID: 20089699
Contributors: Daubeuf S; Lindorfer MA; Taylor RP; Joly E; Hudrisier D
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

Ligand binding but undetected functional response of FcR after their capture by T cells via trogocytosis.

2009-11 | Journal article
DOI: 10.4049/jimmunol.0900821
PMID: 19841164
Contributors: Hudrisier D; Clemenceau B; Balor S; Daubeuf S; Magdeleine E; Daëron M; Bruhns P; Vié H
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

Improving administration regimens of CyaA-based vaccines using TRAP assays to detect antigen-specific CD8(+) T cells directly ex vivo.

2009-09 | Journal article
DOI: 10.1016/j.vaccine.2009.07.035
PMID: 19647811
Contributors: Daubeuf S; Préville X; Momot M; Misseri Y; Joly E; Hudrisier D
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

Suitability of various membrane lipophilic probes for the detection of trogocytosis by flow cytometry.

2009-05 | Journal article
DOI: 10.1002/cyto.a.20679
PMID: 19051238
Contributors: Daubeuf S; Bordier C; Hudrisier D; Joly E
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

Antigp41 antibodies fail to block early events of virological synapses but inhibit HIV spread between T cells.

2009-01 | Journal article
DOI: 10.1097/QAD.0b013e32831ef1a3
PMID: 19098487
Contributors: Massanella M; Puigdomènech I; Cabrera C; Fernandez-Figueras MT; Aucher A; Gaibelet G; Hudrisier D; García E; Bofill M; Clotet B et al.
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

Capture of plasma membrane fragments from target cells by trogocytosis requires signaling in T cells but not in B cells.

2008-06 | Journal article
DOI: 10.1182/blood-2008-01-134155
PMID: 18381976
PMC: PMC2424158
Contributors: Aucher A; Magdeleine E; Joly E; Hudrisier D
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

Prevention of acute and chronic allograft rejection with CD4+CD25+Foxp3+ regulatory T lymphocytes.

2008-01 | Journal article
DOI: 10.1038/nm1688
PMID: 18066074
PMC: PMC2443705
Contributors: Joffre O; Santolaria T; Calise D; Al Saati T; Hudrisier D; Romagnoli P; van Meerwijk JP
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

Chemical labels metabolically installed into the glycoconjugates of the target cell surface can be used to track lymphocyte/target cell interplay via trogocytosis: comparisons with lipophilic dyes and biotin.

2007 | Journal article
DOI: 10.1080/08820130701674596
PMID: 18161525
Contributors: Daubeuf S; Aucher A; Sampathkumar SG; Preville X; Yarema KJ; Hudrisier D
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

Shaping of the autoreactive regulatory T cell repertoire by thymic cortical positive selection.

2007-11 | Journal article
DOI: 10.4049/jimmunol.179.10.6741
PMID: 17982064
PMC: PMC2577800
Contributors: Ribot J; Enault G; Pilipenko S; Huchenq A; Calise M; Hudrisier D; Romagnoli P; van Meerwijk JP
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

Capture of membrane components via trogocytosis occurs in vivo during both dendritic cells and target cells encounter by CD8(+) T cells.

2007-10 | Journal article
DOI: 10.1111/j.1365-3083.2007.01996.x
PMID: 17850589
Contributors: Riond J; Elhmouzi J; Hudrisier D; Gairin JE
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

CD8 T cell responses to myelin oligodendrocyte glycoprotein-derived peptides in humanized HLA-A*0201-transgenic mice.

2007-10 | Journal article
DOI: 10.4049/jimmunol.179.8.5090
PMID: 17911594
Contributors: Mars LT; Bauer J; Gross DA; Bucciarelli F; Firat H; Hudrisier D; Lemonnier F; Kosmatopoulos K; Liblau RS
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

Capture of target cell membrane components via trogocytosis is triggered by a selected set of surface molecules on T or B cells.

2007-03 | Journal article
DOI: 10.4049/jimmunol.178.6.3637
PMID: 17339461
Contributors: Hudrisier D; Aucher A; Puaux AL; Bordier C; Joly E
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

A simple trogocytosis-based method to detect, quantify, characterize and purify antigen-specific live lymphocytes by flow cytometry, via their capture of membrane fragments from antigen-presenting cells.

2006 | Journal article
DOI: 10.1038/nprot.2006.400
PMID: 17406507
Contributors: Daubeuf S; Puaux AL; Joly E; Hudrisier D
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

A very rapid and simple assay based on trogocytosis to detect and measure specific T and B cell reactivity by flow cytometry.

2006-03 | Journal article
DOI: 10.1002/eji.200535407
PMID: 16482513
Contributors: Puaux AL; Campanaud J; Salles A; Préville X; Timmerman B; Joly E; Hudrisier D
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

Molecular signature of recent thymic selection events on effector and regulatory CD4+ T lymphocytes.

2005-11 | Journal article
DOI: 10.4049/jimmunol.175.9.5751
PMID: 16237066
PMC: PMC2346488
Contributors: Romagnoli P; Hudrisier D; van Meerwijk JP
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

T cell activation correlates with an increased proportion of antigen among the materials acquired from target cells.

2005-08 | Journal article
DOI: 10.1002/eji.200526266
PMID: 16021601
Contributors: Hudrisier D; Riond J; Garidou L; Duthoit C; Joly E
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

Induction of antigen-specific tolerance to bone marrow allografts with CD4+CD25+ T lymphocytes.

2004-06 | Journal article
DOI: 10.1182/blood-2004-01-0005
PMID: 14976053
PMC: PMC2516529
Contributors: Joffre O; Gorsse N; Romagnoli P; Hudrisier D; van Meerwijk JP
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

What is trogocytosis and what is its purpose?

2003-09 | Journal article
DOI: 10.1038/ni0903-815
PMID: 12942076
Contributors: Joly E; Hudrisier D
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

The beta1 and beta3 integrins promote T cell receptor-mediated cytotoxic T lymphocyte activation.

2003-07 | Journal article
DOI: 10.1074/jbc.M302709200
PMID: 12690105
Contributors: Doucey MA; Legler DF; Faroudi M; Boucheron N; Baumgaertner P; Naeher D; Cebecauer M; Hudrisier D; Rüegg C; Palmer E et al.
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

Acquisition of viral receptor by NK cells through immunological synapse.

2003-06 | Journal article
DOI: 10.4049/jimmunol.170.12.5993
PMID: 12794126
Contributors: Tabiasco J; Vercellone A; Meggetto F; Hudrisier D; Brousset P; Fournié JJ
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

In vivo maintenance of T-lymphocyte unresponsiveness induced by thymic medullary epithelium requires antigen presentation by radioresistant cells.

2003-01 | Journal article
DOI: 10.1046/j.1365-2567.2003.01546.x
PMID: 12519299
Contributors: Hudrisier D; Feau S; Bonnet V; Romagnoli P; Van Meerwijk JP
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

Synaptic transfer by human gamma delta T cells stimulated with soluble or cellular antigens.

2002-06 | Journal article
DOI: 10.4049/jimmunol.168.12.6336
PMID: 12055250
Contributors: Espinosa E; Tabiasco J; Hudrisier D; Fournié JJ
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

Active trans-synaptic capture of membrane fragments by natural killer cells.

2002-05 | Journal article
DOI: 10.1002/1521-4141(200205)32:5<1502::AID-IMMU1502>3.0.CO;2-Y
PMID: 11981839
Contributors: Tabiasco J; Espinosa E; Hudrisier D; Joly E; Fournié JJ; Vercellone A
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

Intercellular transfer of antigen-presenting cell determinants onto T cells: molecular mechanisms and biological significance.

2002-04 | Journal article
DOI: 10.1096/fj.01-0933rev
PMID: 11919150
Contributors: Hudrisier D; Bongrand P
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

Preferential recognition of self antigens despite normal thymic deletion of CD4(+)CD25(+) regulatory T cells.

2002-02 | Journal article
DOI: 10.4049/jimmunol.168.4.1644
PMID: 11823492
Contributors: Romagnoli P; Hudrisier D; van Meerwijk JP
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

Pleiotropic effects of post-translational modifications on the fate of viral glycopeptides as cytotoxic T cell epitopes.

2001-10 | Journal article
PMID: 11479317
Contributors: Hudrisier D; Riond J; Mazarguil H; Gairin JE
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

Structural and functional identification of major histocompatibility complex class I-restricted self-peptides as naturally occurring molecular mimics of viral antigens. Possible role in CD8+ T cell-mediated, virus-induced autoimmune disease.

2001-06 | Journal article
DOI: 10.1074/jbc.M008864200
PMID: 11278441
Contributors: Hudrisier D; Riond J; Burlet-Schiltz O; von Herrath MG; Lewicki H; Monsarrat B; Oldstone MB; Gairin JE
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

Cutting edge: CTLs rapidly capture membrane fragments from target cells in a TCR signaling-dependent manner.

2001-03 | Journal article
DOI: 10.4049/jimmunol.166.6.3645
PMID: 11238601
Contributors: Hudrisier D; Riond J; Mazarguil H; Gairin JE; Joly E
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

Molecular and functional dissection of the H-2Db-restricted subdominant cytotoxic T-cell response to lymphocytic choriomeningitis virus.

2001-03 | Journal article
DOI: 10.1128/JVI.75.5.2468-2471.2001
PMID: 11160751
PMC: PMC114831
Contributors: Hudrisier D; Riond J; Gairin JE
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

Genetically encoded and post-translationally modified forms of a major histocompatibility complex class I-restricted antigen bearing a glycosylation motif are independently processed and co-presented to cytotoxic T lymphocytes.

1999-12 | Journal article
DOI: 10.1074/jbc.274.51.36274
PMID: 10593916
Contributors: Hudrisier D; Riond J; Mazarguil H; Oldstone MB; Gairin JE
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

Use of a high-affinity peptide that aborts MHC-restricted cytotoxic T lymphocyte activity against multiple viruses in vitro and virus-induced immunopathologic disease in vivo.

1999-04 | Journal article
DOI: 10.1006/viro.1998.9593
PMID: 10191190
Contributors: Oldstone MB; von Herrath M; Lewicki H; Hudrisier D; Whitton JL; Gairin JE
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

Peptide-major histocompatibility complex class I complex: from the structural and molecular basis to pharmacological principles and therapeutic applications.

1998 | Journal article
PMID: 9557394
Contributors: Hudrisier D; Gairin JE
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

Peptide modification or blocking of CD8, resulting in weak TCR signaling, can activate CTL for Fas- but not perforin-dependent cytotoxicity or cytokine production.

1998-12 | Journal article
PMID: 9862728
Contributors: Kessler B; Hudrisier D; Schroeter M; Tschopp J; Cerottini JC; Luescher IF
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

The efficiency of antigen recognition by CD8+ CTL clones is determined by the frequency of serial TCR engagement.

1998-07 | Journal article
PMID: 9670927
Contributors: Hudrisier D; Kessler B; Valitutti S; Horvath C; Cerottini JC; Luescher IF
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

Role of CD8 in aberrant function of cytotoxic T lymphocytes.

1997-12 | Journal article
DOI: 10.1084/jem.186.12.2033
PMID: 9396772
PMC: PMC2199177
Contributors: Kessler B; Hudrisier D; Cerottini JC; Luescher IF
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

The signal sequence of lymphocytic choriomeningitis virus contains an immunodominant cytotoxic T cell epitope that is restricted by both H-2D(b) and H-2K(b) molecules.

1997-07 | Journal article
DOI: 10.1006/viro.1997.8627
PMID: 9234947
Contributors: Hudrisier D; Oldstone MB; Gairin JE
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

Binding of viral antigens to major histocompatibility complex class I H-2Db molecules is controlled by dominant negative elements at peptide non-anchor residues. Implications for peptide selection and presentation.

1996-07 | Journal article
DOI: 10.1074/jbc.271.30.17829
PMID: 8663374
Contributors: Hudrisier D; Mazarguil H; Laval F; Oldstone MB; Gairin JE
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

Discriminated selection among viral peptides with the appropriate anchor residues: implications for the size of the cytotoxic T-lymphocyte repertoire and control of viral infection.

1995-12 | Journal article
PMID: 7494247
PMC: PMC189679
Contributors: Oldstone MB; Lewicki H; Borrow P; Hudrisier D; Gairin JE
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

Relative implication of peptide residues in binding to major histocompatibility complex class I H-2Db: application to the design of high-affinity, allele-specific peptides.

1995-08 | Journal article
DOI: 10.1016/0161-5890(95)00043-E
PMID: 7565816
Contributors: Hudrisier D; Mazarguil H; Oldstone MB; Gairin JE
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central

Optimal lymphocytic choriomeningitis virus sequences restricted by H-2Db major histocompatibility complex class I molecules and presented to cytotoxic T lymphocytes.

1995-04 | Journal article
PMID: 7533855
PMC: PMC188900
Contributors: Gairin JE; Mazarguil H; Hudrisier D; Oldstone MB
Source: Self-asserted source
Denis Hudrisier via Europe PubMed Central
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