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Works (20)

Exposure–response modeling for nausea incidence for cotadutide using a Markov modeling approach

CPT: Pharmacometrics & Systems Pharmacology
2024-09 | Journal article
DOI: 10.1002/psp4.13194
Contributors: Hongtao Yu; Sebastian Ueckert; Lina Zhou; Jenny Cheng; Darren Robertson; Lars Hansen; Armando Flor; Victoria Parker; Bengt Hamrén; Anis A. Khan
Source: check_circle
Crossref

From Plan to Pivot: How Model‐Informed Drug Development Shaped the Dose Strategy of the Zibotentan/Dapagliflozin ZENITH Trials

Clinical Pharmacology & Therapeutics
2024-09 | Journal article
DOI: 10.1002/cpt.3362
Contributors: Anne‐Kristina Mercier; Sebastian Ueckert; Mikael Sunnåker; Bengt Hamrén; Phil Ambery; Peter J. Greasley; Magnus Åstrand
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Crossref

A Markov model of fibrosis development in nonalcoholic fatty liver disease predicts fibrosis progression in clinical cohorts

CPT: Pharmacometrics & Systems Pharmacology
2023-12 | Journal article
DOI: 10.1002/psp4.13052
Contributors: Jane Knöchel; Linnéa Bergenholm; Eman Ibrahim; Stergios Kechagias; Sara Hansson; Mathias Liljeblad; Patrik Nasr; Björn Carlsson; Mattias Ekstedt; Sebastian Ueckert
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Crossref

Evaluation of the effect of erenumab on migraine‐specific questionnaire in patients with chronic and episodic migraine

CPT: Pharmacometrics & Systems Pharmacology
2023-12 | Journal article
DOI: 10.1002/psp4.13048
Contributors: Po‐Wei Chen; Mats O. Karlsson; Sebastian Ueckert; Ari Pritchard‐Bell; Cheng‐Pang Hsu; Sandeep Dutta; Malidi Ahamadi
Source: check_circle
Crossref

How to analyze continuous and discrete repeated measures in small‐sample cross‐over trials?

Biometrics
2023-08-16 | Journal article
DOI: 10.1111/biom.13920
Part of ISSN: 0006-341X
Part of ISSN: 1541-0420
Contributors: Johan Verbeeck; Martin Geroldinger; Konstantin Thiel; Andrew Craig Hooker; Sebastian Ueckert; Mats Karlsson; Arne Cornelius Bathke; Johann Wolfgang Bauer; Geert Molenberghs; Georg Zimmermann
Source: Self-asserted source
Sebastian Ueckert

cLRT‐Mod: An efficient methodology for pharmacometric model‐based analysis of longitudinal phase II dose finding studies under model uncertainty

Statistics in Medicine
2021-05-10 | Journal article
DOI: 10.1002/sim.8913
Part of ISSN: 0277-6715
Part of ISSN: 1097-0258
Contributors: Simon Buatois; Sebastian Ueckert; Nicolas Frey; Sylvie Retout; France Mentré
Source: Self-asserted source
Sebastian Ueckert

Improved numerical stability for the bounded integer model

Journal of Pharmacokinetics and Pharmacodynamics
2021-04-26 | Journal article
DOI: 10.1007/s10928-020-09727-8
Contributors: Sebastian Ueckert; Mats O. Karlsson
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Crossref

Model-Based Conditional Weighted Residuals Analysis for Structural Model Assessment.

The AAPS journal
2019-02-27 | Journal article
DOI: 10.1208/s12248-019-0305-2
PMID: 30815754
PMC: PMC6394649
Source: Self-asserted source
Sebastian Ueckert

Comparison of Model Averaging and Model Selection in Dose Finding Trials Analyzed by Nonlinear Mixed Effect Models.

The AAPS journal
2018-03-29 | Journal article
DOI: 10.1208/s12248-018-0205-x
PMID: 29600418
Source: Self-asserted source
Sebastian Ueckert

Modeling composite assessment data using item response theory

CPT: Pharmacometrics & Systems Pharmacology
2018-03-01 | Journal article
DOI: 10.1002/psp4.12280
Part of ISSN: 2163-8306
Contributors: Sebastian Ueckert
Source: Self-asserted source
Sebastian Ueckert via Crossref Metadata Search

A new method for evaluation of the Fisher information matrix for discrete mixed effect models using Monte Carlo sampling and adaptive Gaussian quadrature

Computational Statistics & Data Analysis
2017-07 | Journal article
DOI: 10.1016/j.csda.2016.10.011
Contributors: Sebastian Ueckert; France Mentré
Source: check_circle
Crossref

Item Response Theory as an Efficient Tool to Describe a Heterogeneous Clinical Rating Scale in De Novo Idiopathic Parkinson’s Disease Patients

Pharmaceutical Research
2017-07-10 | Journal article
DOI: 10.1007/s11095-017-2216-1
Part of ISSN: 0724-8741
Contributors: Simon Buatois; Sylvie Retout; Nicolas Frey; Sebastian Ueckert
Source: Self-asserted source
Sebastian Ueckert via Crossref Metadata Search

Application of Item Response Theory to Modeling of Expanded Disability Status Scale in Multiple Sclerosis

The AAPS Journal
2016-09 | Journal article
DOI: 10.1208/s12248-016-9977-z
Part of ISSN: 1550-7416
Contributors: A. M. Novakovic; E. H. J. Krekels; A. Munafo; S. Ueckert; M. O. Karlsson
Source: Self-asserted source
Sebastian Ueckert via Crossref Metadata Search

An MCMC method for the evaluation of the Fisher information matrix for non-linear mixed effect models

Biostatistics
2016-05-10 | Journal article
DOI: 10.1093/biostatistics/kxw020
Part of ISSN: 1465-4644
Contributors: Marie-Karelle Riviere; Sebastian Ueckert; France Mentré
Source: Self-asserted source
Sebastian Ueckert via Crossref Metadata Search

Accelerating Monte Carlo power studies through parametric power estimation

Journal of Pharmacokinetics and Pharmacodynamics
2016-03-02 | Journal article
DOI: 10.1007/s10928-016-9468-y
Source: check_circle
Crossref

Improved Utilization of ADAS-Cog Assessment Data Through Item Response Theory Based Pharmacometric Modeling

2014 | Journal article
DOI:

10.1007/s11095-014-1315-5

Part of ISSN:

0724-8741
Source: Self-asserted source
Sebastian Ueckert via Crossref Metadata Search

Evaluation of bias, precision, robustness and runtime for estimation methods in NONMEM 7

Journal of Pharmacokinetics and Pharmacodynamics
2014-05-07 | Journal article
DOI: 10.1007/s10928-014-9359-z
Part of ISSN: 1567-567X
Contributors: Åsa M. Johansson; Sebastian Ueckert; Elodie L. Plan; Andrew C. Hooker; Mats O. Karlsson
Source: Self-asserted source
Sebastian Ueckert via Crossref Metadata Search

A novel BACE inhibitor (PF-05297909): A two-part adaptive design to evaluate safety, pharmacokinetics and pharmacodynamics for modifying beta-amyloid in a first-in-human study

2013 | Journal article
DOI:

10.1016/j.jalz.2013.05.578

Part of ISSN:

1552-5260
Source: Self-asserted source
Sebastian Ueckert via Crossref Metadata Search

Optimizing disease progression study designs for drug effect discrimination

2013 | Journal article
DOI:

10.1007/s10928-013-9331-3

Part of ISSN:

1567-567X
Source: Self-asserted source
Sebastian Ueckert via Crossref Metadata Search

PopED: An extended, parallelized, nonlinear mixed effects models optimal design tool

2012 | Journal article
DOI:

10.1016/j.cmpb.2012.05.005

Part of ISSN:

0169-2607
Source: Self-asserted source
Sebastian Ueckert via Crossref Metadata Search

Peer review (21 reviews for 9 publications/grants)

Review activity for British journal of clinical pharmacology (1)
Review activity for Clinical pharmacology & therapeutics. (2)
Review activity for CPT: pharmacometrics & systems pharmacology. (2)
Review activity for Journal of pharmacokinetics and pharmacodynamics. (1)
Review activity for Journal of pharmacokinetics and pharmacodynamics. (8)
Review activity for Movement disorders. (1)
Review activity for Pharmaceutical research. (2)
Review activity for Pharmaceutical statistics. (1)
Review activity for The AAPS journal. (3)
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