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Works (26)

Regulatory networks may evolve to favor adaptive foresight

PLOS Biology
2024-12-06 | Journal article
Contributors: Alejandro Couce
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Crossref

Novel Fosfomycin Resistance Mechanism in Pseudomonas entomophila Due to Atypical Pho Regulon Control of GlpT

Antibiotics
2024-10-26 | Journal article
Contributors: Laura Sánchez-Maroto; Pablo Gella; Alejandro Couce
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Crossref

Reversion to metabolic autonomy underpins evolutionary rescue of a bacterial obligate mutualism

2024-07-02 | Preprint
Contributors: Ignacio J. Melero-Jiménez; Yael Sorokin; Ami Merlin; Alejandro Couce; Jonathan Friedman
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Crossref

Changing fitness effects of mutations through long-term bacterial evolution

Science
2024-01-26 | Journal article
Contributors: Alejandro Couce; Anurag Limdi; Melanie Magnan; Siân V. Owen; Cristina M. Herren; Richard E. Lenski; Olivier Tenaillon; Michael Baym
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Crossref

Predictability shifts from local to global rules during bacterial adaptation

2022-05-17 | Preprint
Contributors: Alejandro Couce; Melanie Magnan; Richard E. Lenski; Olivier Tenaillon
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Crossref

Mutation bias and GC content shape antimutator invasions

Nature Communications
2019-07-15 | Journal article
Contributors: Alejandro Couce; Olivier Tenaillon
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Crossref
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The role of mutational spectrum in the selection against mutator alleles

2019-02-08 | Other
Contributors: Alejandro Couce; Olivier Tenaillon
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Crossref

Flux, toxicity and protein expression costs shape genetic interaction in a metabolic pathway

2018-07 | Other
OTHER-ID:

PPR7707

Contributors: Kemble HE; Eisenhauer C; Couce A; Chapron A; Magnan M; Gautier G; Le Nagard H; Nghe P; Tenaillon O
Source: Self-asserted source
Alejandro Couce via Europe PubMed Central

Parallel Evolution of High-Level Aminoglycoside Resistance in Escherichia coli Under Low and High Mutation Supply Rates.

Frontiers in microbiology
2018-03 | Journal article
Contributors: Ibacache-Quiroga C; Oliveros JC; Couce A; Blázquez J
Source: Self-asserted source
Alejandro Couce via Europe PubMed Central
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Preferred source (of 2)‎

Mutator genomes decay, despite sustained fitness gains, in a long-term experiment with bacteria.

Proceedings of the National Academy of Sciences of the United States of America
2017-10 | Journal article
Contributors: Couce A; Caudwell LV; Feinauer C; Hindré T; Feugeas JP; Weigt M; Lenski RE; Schneider D; Tenaillon O
Source: Self-asserted source
Alejandro Couce via Europe PubMed Central
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Preferred source (of 2)‎

Determinants of genetic diversity of spontaneous drug resistance in bacteria

Genetics
2016 | Journal article
EID:

2-s2.0-84979951015

Contributors: Couce, A.; Rodríguez-Rojas, A.; Blázquez, J.
Source: Self-asserted source
Alejandro Couce via Scopus - Elsevier

Correction to ‘Bypass of genetic constraints during mutator evolution to antibiotic resistance’

Proceedings of the Royal Society B: Biological Sciences
2016-08-31 | Journal article
Contributors: Alejandro Couce; Alexandro Rodríguez-Rojas; Jesús Blázquez
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Crossref

Determinants of Genetic Diversity of Spontaneous Drug-Resistance in Bacteria.

2016-05 | Journal article
Contributors: Couce A Fax 33; Rodríguez-Rojas A; Blázquez J
Source: Self-asserted source
Alejandro Couce via Europe PubMed Central

Intrapopulation variability in mutator prevalence among urinary tract infection isolates of Escherichia coli.

2016-03 | Journal article
Contributors: Couce A; Alonso N; Costas C; Oliver A; Blázquez J
Source: Self-asserted source
Alejandro Couce via Europe PubMed Central
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Preferred source (of 2)‎

The rule of declining adaptability in microbial evolution experiments.

2015 | Journal article
Contributors: Couce A; Tenaillon OA
Source: Self-asserted source
Alejandro Couce via Europe PubMed Central
grade
Preferred source (of 2)‎

Bypass of genetic constraints during mutator evolution to antibiotic resistance.

2015-04 | Journal article
Contributors: Couce A; Rodríguez-Rojas A; Blázquez J
Source: Self-asserted source
Alejandro Couce via Europe PubMed Central
grade
Preferred source (of 2)‎

Mutational spectrum drives the rise of mutator bacteria.

2013 | Journal article
Contributors: Couce A; Guelfo JR; Blázquez J
Source: Self-asserted source
Alejandro Couce via Europe PubMed Central
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Preferred source (of 2)‎

Antibiotics and antibiotic resistance: a bitter fight against evolution.

2013-08 | Journal article
Contributors: Rodríguez-Rojas A; Rodríguez-Beltrán J; Couce A; Blázquez J
Source: Self-asserted source
Alejandro Couce via Europe PubMed Central
grade
Preferred source (of 2)‎

The Escherichia coli SOS gene dinF protects against oxidative stress and bile salts.

2012 | Journal article
Contributors: Rodríguez-Beltrán J; Rodríguez-Rojas A; Guelfo JR; Couce A; Blázquez J
Source: Self-asserted source
Alejandro Couce via Europe PubMed Central
grade
Preferred source (of 2)‎

Antimicrobials as promoters of genetic variation.

2012-10 | Journal article
Contributors: Blázquez J; Couce A; Rodríguez-Beltrán J; Rodríguez-Rojas A
Source: Self-asserted source
Alejandro Couce via Europe PubMed Central
grade
Preferred source (of 2)‎

Genomewide overexpression screen for fosfomycin resistance in Escherichia coli: MurA confers clinical resistance at low fitness cost.

2012-05 | Journal article
Contributors: Couce A; Briales A; Rodríguez-Rojas A; Costas C; Pascual A; Blázquez J
Source: Self-asserted source
Alejandro Couce via Europe PubMed Central
grade
Preferred source (of 2)‎

Estimating mutation rates in low-replication experiments.

2011-09 | Journal article
Contributors: Couce A; Blázquez J
Source: Self-asserted source
Alejandro Couce via Europe PubMed Central
grade
Preferred source (of 2)‎

Effect of recA inactivation on mutagenesis of Escherichia coli exposed to sublethal concentrations of antimicrobials.

2011-03 | Journal article
Contributors: Thi TD; López E; Rodríguez-Rojas A; Rodríguez-Beltrán J; Couce A; Guelfo JR; Castañeda-García A; Blázquez J
Source: Self-asserted source
Alejandro Couce via Europe PubMed Central
grade
Preferred source (of 2)‎

Assessing the emergence of resistance: the absence of biological cost in vivo may compromise fosfomycin treatments for P. aeruginosa infections.

2010 | Journal article
Contributors: Rodríguez-Rojas A; Maciá MD; Couce A; Gómez C; Castañeda-García A; Oliver A; Blázquez J
Source: Self-asserted source
Alejandro Couce via Europe PubMed Central
grade
Preferred source (of 2)‎

Frequency of spontaneous resistance to fosfomycin combined with different antibiotics in Pseudomonas aeruginosa.

2010-11 | Journal article
Contributors: Rodríguez-Rojas A; Couce A; Blázquez J
Source: Self-asserted source
Alejandro Couce via Europe PubMed Central
grade
Preferred source (of 2)‎

Side effects of antibiotics on genetic variability.

2009-05 | Journal article
Contributors: Couce A; Blázquez J
Source: Self-asserted source
Alejandro Couce via Europe PubMed Central
grade
Preferred source (of 2)‎

Peer review (1 review for 1 publication/grant)

Review activity for PLoS biology. (1)