Personal information

spatial memory, rats , allothetic memory, cognition, place avoidance method, idiothetic memory

Biography

BORN - Warsaw, Poland; Gender – female
DEGREES - M. Sc. University of Warsaw, 1976; Ph. D. -1986; D.Sc. – 2005.
POSITION
Permanent faculty, Nencki Institute; Assistant Prof. - since 1988; Associate Prof. – since 2005
PROFESSIONAL ASSOCIATION
Polish Neuroscience Society (PTBUN) – member since 1992
Member of Society for Neuroscience – since 2008
RESEARCH INTEREST is devoted to neural substrates of spatial memory (allothetic and /or idiothetic) and cognition, and their functions, in standard and pathology (lesion; neurodegeneration; administration of NMDAR’s antagonists) of the brain in rats. In these studies a role of hippocampus and retrosplenial cortex are considerate. Memory and cognition processes have been studied in different variants of the behavioral spatial place avoidance method in rats. To image changes in the brain activation when rats learned a spatial tasks in allo- and/or idiothetic conditions, functional mapping by c-Fos staining are perform in intact and lesioned rats. All behavioral, histochemical and immunohistochemiacl methods give us a chance to made a progress in understanding how the nervous system functions in standard and pathology.

Activities

Employment (1)

Nencki Institute of Experimental Biology PAS: Warszawa, Warsaw, PL

1977-05-23 to present | Assoc. Prof (Neurophysiology)
Employment
Source: Self-asserted source
Malgorzata Wesierska

Education and qualifications (3)

Instytut Biologii Doswiadczalnej im M Nenckiego Polskiej Akademii Nauk: Warszawa, PL

2006 to present | Habilitacja
Education
Source: Self-asserted source
Malgorzata Wesierska

Instytut Biologii Doswiadczalnej im M Nenckiego Polskiej Akademii Nauk: Warsaw, PL

1986 to present | PhD
Education
Source: Self-asserted source
Malgorzata Wesierska

University of Warsaw: Warsaw, Warsaw, PL

1976-06-10 to present | M.Sc. (Physiology)
Education
Source: Self-asserted source
Malgorzata Wesierska

Professional activities (6)

Prezydent Rzeczypospolitej Polskiej: Warszawa, PL

Silver Cross of Merit 2008 (Prac. Neuropsychologii)
Distinction
Source: Self-asserted source
Malgorzata Wesierska

Polskie Towarzystwo Badan Ukladu Nerwowego: Warszawa, PL

Membership
Source: Self-asserted source
Malgorzata Wesierska

Academy of Sciences of the Czech Republic: Prague, CZ

1997-01-06 to present | guest researcher, honorary fellow (Institute of Physiology, Czech Academy of Sciences Dpt. Of Neurophysiology of Memory)
Invited position
Source: Self-asserted source
Malgorzata Wesierska

Prezydent Rzeczypospolitej Polskiej: Warszawa, PL

2018 | Gold Cross of Merit
Distinction
Source: Self-asserted source
Malgorzata Wesierska

Institute of Physiology: Prague, CZ

2014-05-22 | Diploma of Achievement from the Institute of Physiology Academy of Sciences of the Czech Republic (Dpt. of Neurophysiology of Memory)
Distinction
Source: Self-asserted source
Malgorzata Wesierska

Society for Neuroscience: Washington, DC, US

2008 to 2011
Membership
Source: Self-asserted source
Malgorzata Wesierska

Funding (5)

Relacje między mózgiem a zachowaniem w zdrowiu i chorobach:pamięć i uczenie.

2017-01 to 2019-12 | Grant
Polska Akademia Nauk (Warsaw, PL)
GRANT_NUMBER:

Polsko-Czeski projekt na wymianę naukową (współwykonawca)

Source: Self-asserted source
Malgorzata Wesierska

Nawigacja przestrzenna a funkcje poznawcze: od badań podstawowych do klinicznych.

2015 to 2017 | Grant
Joint Research Centre (Warsaw, PL)
GRANT_NUMBER:

MNiSW Polsko-Czeska umowa bilateralna (kierownik)

Source: Self-asserted source
Malgorzata Wesierska

Udział hipokampa i kory przedczołowej w funkcjonowaniu systemu przestrzennej pamięci operacyjnej w modelu szczurzym

2014-07 to 2017-07 | Grant
Narodowe Centrum Nauki (Kraków, PL)
Part of GRANT_NUMBER:

UMO-2013/11/N.NNZ4/02198 (opiekun naukowy)

Source: Self-asserted source
Malgorzata Wesierska

Wpływ nieinwazyjnej prądowej stymulacji mózgu na mechanizmy usprawniania pamięci operacyjnej

2011-02 to 2014-05 | Grant
MNiSW (Warsaw, PL)
GRANT_NUMBER:

8165/B/P01/2011/40 (kierownik)

Source: Self-asserted source
Malgorzata Wesierska

Kompensacja systemowa po uszkodzeniach struktur mózgowych w modelu pamięci deklaratywnej

2007-11 to 2011-11 | Grant
MNiSW (Warsaw, PL)
GRANT_NUMBER:

3117/B/P01/2007/33 3P04C (kierownik)

Source: Self-asserted source
Malgorzata Wesierska

Works (43)

Combination of dasatinib and quercetin improves cognitive abilities in aged male Wistar rats, alleviates inflammation and changes hippocampal synaptic plasticity and histone H3 methylation profile

Aging
2022-01-31 | Journal article
Part of ISSN: 1945-4589
Source: Self-asserted source
Malgorzata Wesierska

Coating-Dependent Neurotoxicity of Silver Nanoparticles—An In Vivo Study on Hippocampal Oxidative Stress and Neurosteroids

International Journal of Molecular Sciences
2022-01-25 | Journal article
Part of ISSN: 1422-0067
Source: Self-asserted source
Malgorzata Wesierska

Silver Nanoparticles Impair Cognitive Functions and Modify the Hippocampal Level of Neurotransmitters in a Coating-Dependent Manner

International Journal of Molecular Sciences
2021-11-24 | Journal article
Part of ISSN: 1422-0067
Source: Self-asserted source
Malgorzata Wesierska

Spatial working memory in rats: Crucial role of the hippocampus in the allothetic place avoidance alternation task demanding stimuli segregation

Behavioural Brain Research
2021-08 | Journal article
Part of ISSN: 0166-4328
Source: Self-asserted source
Malgorzata Wesierska

Cellular Senescence in Brain Aging

Frontiers in Aging Neuroscience
2021-02-25 | Journal article
Part of ISSN: 1663-4365
Source: Self-asserted source
Malgorzata Wesierska

A therapeutic dose of memantine improves the performance of rats in an active place avoidance task under the continuous dissociation of distal room and proximal arena cues

Neurobiology of Learning and Memory
2019-07 | Journal article
Part of ISSN: 1074-7427
Source: Self-asserted source
Malgorzata Wesierska

A therapeutic dose of memantine improves the performance of rats in an active place avoidance task under the continuous dissociation of distal room and proximal arena cues

Neurobiology of Learning and Memory
2019-07 | Journal article
Source: Self-asserted source
Malgorzata Wesierska

Silver ions are responsible for memory impairment induced by oral administration of silver nanoparticles

Toxicology Letters
2018 | Journal article
WOSUID:

WOS:000430360500016

Contributors: Wesierska, M.; Dziendzikowska, K.; Gromadzka-Ostrowska, J.; Dudek, J.; Polkowska-Motrenko, H.; Audinot, J. N.; Gutleb, A. C.; Lankoff, A.; Kruszewski, M.
Source: Self-asserted source
Malgorzata Wesierska via ResearcherID

Active Allothetic Place Avoidance task: silver nanoparticles (AgNPs)

Publicly available in RepOD since: 2017-06-30 10:45 (CEST)
2017-06-30 | Dataset
Source: Self-asserted source
Malgorzata Wesierska

MK-801 and memantine act differently on short-term memory tested with different time-intervals in the Morris water maze test

Behavioural Brain Research
2016 | Journal article
WOSUID:

WOS:000380418200002

Contributors: Duda, W.; Wesierska, M.; Ostaszewski, P.; Vales, K.; Nekovarova, T.; Stuchlik, A.
Source: Self-asserted source
Malgorzata Wesierska via ResearcherID

Spatial memory formation differentially affects c-Fos expression in retrosplenial areas during place avoidance training in rats

Acta Neurobiologiae Experimentalis
2016 | Journal article
WOSUID:

WOS:000385338800009

Contributors: Malinowska, M.; Niewiadomska, M.; Wesierska, M.
Source: Self-asserted source
Malgorzata Wesierska via ResearcherID

Comparison of spatial learning in the partially baited radial-arm maze task between commonly used rat strains: Wistar, Spargue-Dawley, Long-Evans, and outcrossed Wistar/Sprague-Dawley

Learning & Behavior
2015 | Journal article
WOSUID:

WOS:000349315500008

Contributors: Gokcek-Sarac, C.; Wesierska, M.; Jakubowska-Dogru, E.
Source: Self-asserted source
Malgorzata Wesierska via ResearcherID

Low-dose memantine-induced working memory improvement in the allothetic place avoidance alternation task (APAAT) in young adult male rats

Frontiers in Behavioral Neuroscience
2013 | Journal article
WOSUID:

WOS:000328706900001

Contributors: Wesierska, M. J.; Duda, W.; Dockery, C. A.
Source: Self-asserted source
Malgorzata Wesierska via ResearcherID

Place Avoidance Tasks as Tools in the Behavioral Neuroscience of Learning and Memory

Physiological Research
2013 | Journal article
Source: Self-asserted source
Malgorzata Wesierska

Jan Bures (1926-2012)

Acta Neurobiologiae Experimentalis
2012 | Journal article
Source: Self-asserted source
Malgorzata Wesierska

Cumulative benefits of frontal transcranial direct current stimulation on visuospatial working memory training and skill learning in rats

Neurobiology of Learning and Memory
2011 | Journal article
WOSUID:

WOS:000296400900004

Contributors: Dockery, C. A.; Liebetanz, D.; Birbaumer, N.; Malinowska, M.; Wesierska, M. J.
Source: Self-asserted source
Malgorzata Wesierska via ResearcherID

Divergent effects of age on performance in spatial associative learning and real idiothetic memory in humans

Behavioural Brain Research
2011 | Journal article
WOSUID:

WOS:000289137200012

Contributors: Skolimowska, J.; Wesierska, M.; Lewandowska, M.; Szymaszek, A.; Szelag, E.
Source: Self-asserted source
Malgorzata Wesierska via ResearcherID

A spatial paradigm, the allothetic place avoidance alternation task, for testing visuospatial working memory and skill learning in rats

Journal of Neuroscience Methods
2010 | Journal article
WOSUID:

WOS:000281927100009

Contributors: Dockery, Colleen A.; Wesierska, Malgorzata J.
Source: Self-asserted source
Malgorzata Wesierska via ResearcherID

Neuropsychological rehabilitation from brain-behavior perspective

New Ideas in Studying and Supporting Development of Exceptional People
2009 | Book chapter
Source: Self-asserted source
Malgorzata Wesierska

Retrosplenial cortex lesion affected segregation of spatial information in place avoidance task in the rat

Neurobiology of Learning and Memory
2009 | Journal article
WOSUID:

WOS:000263154100006

Contributors: Wesierska, Malgorzata; Adamska, Iwona; Malinowska, Monika
Source: Self-asserted source
Malgorzata Wesierska via ResearcherID

KAZIMIERZ JAN ZIELINSKI (1929-2004) He was an outstanding scientist. Publishes several works

Instytut Biologii Doswiadczalnej Im Marcelego Nenckiego: Historia I Terazniejszosc, Tom Iii: Wspomienie I Refleksje. Memories and Reflections
2008 | Book
WOSUID:

WOS:000277771900030

Contributors: Werka, T.; Walasek, G.; Wesierska, M.; Jakubowska-Dogru, E.; Kuznicki, L.
Source: Self-asserted source
Malgorzata Wesierska via ResearcherID

Cognitive flexibility but not cognitive coordination is affected in rats with toxic liver failure

Behavioural Brain Research
2006 | Journal article
WOSUID:

WOS:000238306200008

Contributors: Wesierska, M.; Klinowska, H. D.; Adamska, I.; Fresko, I.; Sadowska, J.; Albrecht, J.
Source: Self-asserted source
Malgorzata Wesierska via ResearcherID

Beyond memory, navigation, and inhibition: Behavioral evidence for hippocampus-dependent cognitive coordination in the rat

Journal of Neuroscience
2005 | Journal article
WOSUID:

WOS:000227343800027

Contributors: Wesierska, M.; Dockery, C.; Fenton, A. A.
Source: Self-asserted source
Malgorzata Wesierska via ResearcherID

Hippocampus-dependent cognitive coordination in rats

Schizophrenia Bulletin
2005 | Journal article
WOSUID:

WOS:000228241200331

Contributors: Fenton, A. A.; Wesierska, M.; Klement, D.; Olypher, A. V.
Source: Self-asserted source
Malgorzata Wesierska via ResearcherID

An experimental and computational model of cognitive disorganization in the rat

Biological Psychiatry
2004 | Journal article
WOSUID:

WOS:000220755300539

Contributors: Fenton, A. A.; Wesierska, M.; Klement, D.; Olypher, A. V.
Source: Self-asserted source
Malgorzata Wesierska via ResearcherID
grade
Preferred source (of 2)‎

Behavior of the gray short-tailed opossum (Monodelphis domestica) in the open field and in response to a new object, in comparison with the rat

Behavioural Brain Research
2003 | Journal article
WOSUID:

WOS:000184240500004

Contributors: Wesierska, M.; Walasek, G.; Kilijanek, J.; Djavadian, R. L.; Turlejski, K.
Source: Self-asserted source
Malgorzata Wesierska via ResearcherID

Hippocampus-dependent retrieval and hippocampus-independent extinction of place avoidance navigation, and stress-induced out-of-context activation of a memory revealed by reversible lesion experiments in rats

Physiological Research
2002 | Journal article
Source: Self-asserted source
Malgorzata Wesierska

Effect of neonatal dentate gyrus lesion on allothetic and idiothetic navigation in rats

Neurobiology of Learning and Memory
2001 | Journal article
WOSUID:

WOS:000167283400007

Contributors: Czeh, B.; Stuchlik, A.; Wesierska, M.; Cimadevilla, J. M.; Pokorny, J.; Seress, L.; Bures, J.
Source: Self-asserted source
Malgorzata Wesierska via ResearcherID

Inactivating one hippocampus impairs avoidance of a stable room-defined place during dissociation of arena cues from room cues by rotation of the arena

Proceedings of the National Academy of Sciences of the United States of America
2001 | Journal article
WOSUID:

WOS:000167521300106

Contributors: Cimadevilla, J. M.; Wesierska, M.; Fenton, A. A.; Bures, J.
Source: Self-asserted source
Malgorzata Wesierska via ResearcherID

Spontaneous behavior of the gray short-tailed opossum (Monodelphis domestica) in the elevated plus-maze: comparison with Long-Evans rats

Acta Neurobiologiae Experimentalis
2000 | Journal article
Source: Self-asserted source
Malgorzata Wesierska

Both here and there: Simultaneous expression of autonomous spatial memories in rats

Proceedings of the National Academy of Sciences of the United States of America
1998 | Journal article
WOSUID:

WOS:000075957100088

Contributors: Fenton, A. A.; Wesierska, M.; Kaminsky, Y.; Bures, J.
Source: Self-asserted source
Malgorzata Wesierska via ResearcherID

Place avoidance in absence of extra-maze cues

European Journal of Neuroscience
1998 | Journal article
WOSUID:

WOS:000074749401498

Contributors: Wesierska, M.; Fenton, A. A.; Bures, J.
Source: Self-asserted source
Malgorzata Wesierska via ResearcherID

Rodent navigation after dissociation of the allocentric and idiothetic representations of space

Neuropharmacology
1998 | Journal article
WOSUID:

WOS:000074794700026

Contributors: Bures, J.; Fenton, A. A.; Kaminsky, Y.; Wesierska, M.; Zahalka, A.
Source: Self-asserted source
Malgorzata Wesierska via ResearcherID

CONDITIONING OF FEAR AND CONDITIONING OF SAFETY IN RATS

Acta Neurobiologiae Experimentalis
1995 | Journal article
Source: Self-asserted source
Malgorzata Wesierska

HABITUATION OF THE ORIENTING RESPONSE TO AUDITORY AND VISUAL-STIMULI IN RATS TRAINED TO PRESS A BAR

Acta Neurobiologiae Experimentalis
1994 | Journal article
Source: Self-asserted source
Malgorzata Wesierska

EFFECTS OF PARTIAL LESION OF DORSAL HIPPOCAMPAL AFFERENT AND GM1 GANGLIOSIDE TREATMENT ON CONDITIONED EMOTIONAL RESPONSE AND HIPPOCAMPAL AFFERENT MARKERS IN RATS

Behavioural Brain Research
1993 | Journal article
WOSUID:

WOS:A1993LH83900008

Contributors: Zielinski, K.; Walasek, G.; Werka, T.; Wesierska, M.; Gradkowska, M.; Oderfeldnowak, B.
Source: Self-asserted source
Malgorzata Wesierska via ResearcherID

DIFFERENTIAL EFFECT OF PRIOR PARADOXICAL SLEEP-DEPRIVATION ON CONDITIONED TASTE-AVERSION, NEOPHOBIA AND ATTENUATION OF NEOPHOBIA TO SOLID FOOD IN RATS

Behavioural Brain Research
1988 | Journal article
WOSUID:

WOS:A1988M036200004

Contributors: Wesierska, M.; Buresova, O.; Bures, J.
Source: Self-asserted source
Malgorzata Wesierska via ResearcherID

GENERALIZATION OF A CONDITIONED INHIBITOR OF RESPONSE SUPPRESSION IN RATS

Acta Neurobiologiae Experimentalis
1986 | Journal article
PMID: 3739758
Source: Self-asserted source
Malgorzata Wesierska

THE EFFECT OF PARADOXICAL SLEEP-DEPRIVATION ON NEOPHOBIA AND CONDITIONED TASTE-AVERSION TO SOLID FOOD

Physiologia Bohemoslovaca
1986 | Journal article
WOSUID:

WOS:A1986G471900132

Contributors: Wesierska, M.; Buresova, O.; Bures, J.
Source: Self-asserted source
Malgorzata Wesierska via ResearcherID

CONDITIONED INHIBITOR OF THE CONDITIONED EMOTIONAL RESPONSE IN RATS

Physiologia Bohemoslovaca
1985 | Journal article
Source: Self-asserted source
Malgorzata Wesierska

EXTINCTION, REINSTATEMENT AND SPONTANEOUS-RECOVERY OF CONDITIONED SUPPRESSION IN RATS AND THE STABILITY OF CONDITIONED INHIBITOR PERFORMANCE

Acta Neurobiologiae Experimentalis
1985 | Journal article
Source: Self-asserted source
Malgorzata Wesierska
grade
Preferred source (of 4)‎

ENHANCEMENT OF BAR-PRESSING RATE IN RATS BY THE CONDITIONED INHIBITOR OF THE CER

Acta Neurobiologiae Experimentalis
1980 | Journal article
Source: Self-asserted source
Malgorzata Wesierska

EFFECT OF DENSITY ON DEVELOPMENTAL RHYTHMS IN DERMESTES-VULPINUS

Bulletin De L Academie Polonaise Des Sciences-Serie Des Sciences Biologiques
1979 | Journal article
WOSUID:

WOS:A1979KL51200012

Contributors: Sobczyk, J.; Cymborowski, B.; Wesierska, M.
Source: Self-asserted source
Malgorzata Wesierska via ResearcherID