Personal information

Emails & domains

Verified email domains

Other IDs

Scopus Author ID: 55924577700

Keywords

Calcium (Ca2+), Hepatocellular Carcinoma, CACNA1H (Cav3.2), Radiofrequency, Electromagnetic fields, Amplitude Modulated, TheraBionic

Countries

United States

Biography

Administration of tumor-specific frequencies by means of a spoon-shaped antenna has led to tumor shrinkage and long-term responses in patients with breast cancer and hepatocellular carcinoma. I investigate the mechanism of action for tumor-specific amplitude-modulated radiofrequency electromagnetic fields (AM RF EMF) which are used as a novel treatment for cancer (i.e. hepatocellular carcinoma, breast cancer, & glioblastoma).

I have identified the mechanism by which tumor-specific frequencies initiate anti-proliferation as well as cancer stem cell down-regulating effects in tumor cells. Specifically, Ca2+ influx through Cav3.2 T-type calcium channel is the necessary and sufficient event leading to these effects. Additionally, the clinical assessment of fifty-nine patients treated with hepatocellular carcinoma-specific AM RF EMF (HCCMF) shows that it increases overall survival (OS) by 34% without significant adverse events.

Activities

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Employment (3)

Wayne State University: Detroit, Michigan, US

2023-11-15 to present | Assistant Professor (Oncology)
Employment
Source: Self-asserted source
Hugo Jimenez

Atrium Health Wake Forest Baptist: Winston-Salem, NC, US

2022-02-27 to 2023-11-14 | Instructor (Cancer Biology)
Employment
Source: Self-asserted source
Hugo Jimenez

Wake Forest Baptist Medical Center: Winston-Salem, NC, US

2018-05 to 2022-02-26 | Post-Doctoral Researcher (Cancer Biology)
Employment
Source: Self-asserted source
Hugo Jimenez

Education and qualifications (3)

Wake Forest University: Winston-Salem, NC, US

2014-03 to 2018-05 | Graduate Student (Cancer Biology)
Qualification
Source: Self-asserted source
Hugo Jimenez

Rush University: Chicago, IL, US

2008-09 to 2010-06 | MS
Education
Source: Self-asserted source
Hugo Jimenez

Benedictine University: Lisle, Illinois, US

2003-08 to 2008-05 | BS
Education
Source: Self-asserted source
Hugo Jimenez

Professional activities (1)

The Bioelectromagnetics Society: District of Columbia, US

2021-10 to present | Full Member
Membership
Source: Self-asserted source
Hugo Jimenez

Funding (1)

Signaling and Biotechnology Program Pilot

2022-04 to 2023-04 | Grant
Comprehensive Cancer Center at Wake Forest Baptist Medical Center (NC, NC, US)
Source: Self-asserted source
Hugo Jimenez

Works (13)

TGFβ in Pancreas and Colorectal Cancer: Opportunities to Overcome Therapeutic Resistance

Clinical Cancer Research
2024-09-03 | Journal article
DOI: 10.1158/1078-0432.CCR-24-0468
Contributors: Allan M. Johansen; Steven D. Forsythe; Callum T. McGrath; Grayson Barker; Hugo Jimenez; Ravi K. Paluri; Boris C. Pasche
Source: check_circle
Crossref

TGFBR1*6A enhances breast cancer development through downregulation of p27

2023-06-26 | Preprint
DOI: 10.21203/rs.3.rs-2997389/v1
Contributors: Kojo Agyemang; Allan Johansen; Grayson Barker; Michael Pennison; Hugo Jimenez; Kimberly Sheffield; Minghui Wang; Ralph D'Agostino; Kounosuke Watabe; Antonio di Cristofano et al.
Source: check_circle
Crossref

TGFBR1*6A as a modifier of breast cancer risk and progression: advances and future prospects

npj Breast Cancer
2022-07-19 | Journal article
DOI: 10.1038/s41523-022-00446-6
Contributors: Kojo Agyemang; Allan M. Johansen; Grayson W. Barker; Michael J. Pennison; Kimberly Sheffield; Hugo Jimenez; Carl Blackman; Sambad Sharma; Patrick A. Fordjour; Ravi Singh et al.
Source: check_circle
Crossref

Safety and Efficacy of amplitude-modulated radiofrequency electromagnetic fields in advanced hepatocellular carcinoma

4open
2021 | Journal article
DOI: 10.1051/fopen/2021003
Part of ISSN: 2557-0250
Source: Self-asserted source
Hugo Jimenez

Toll‐like receptor‐4 deficiency inhibits ultraviolet radiation‐induced tumor development by modulation of immune and inflammatory responses

Molecular Carcinogenesis
2021-01 | Journal article
DOI: 10.1002/mc.23271
Part of ISSN: 0899-1987
Part of ISSN: 1098-2744
Source: Self-asserted source
Hugo Jimenez

Comments on ‘Search for tumor-specific frequencies of amplitude modulated 27 MHz electromagnetic fields in mice with hepatocarcinoma xenografted tumors’

International Journal of Radiation Biology
2020-07-02 | Journal article
DOI: 10.1080/09553002.2020.1748740
Contributors: Hugo Jimenez; Sambad Sharma; Kimberly Sheffield; Kojo Agyemang; Allan Johansen; Carl Blackman; Kounosuke Watabe; Alexandre Barbault; Boris Pasche
Source: check_circle
Crossref

Tumour-specific amplitude-modulated radiofrequency electromagnetic fields induce differentiation of hepatocellular carcinoma via targeting Cav3.2 T-type voltage-gated calcium channels and Ca2+ influx

EBioMedicine
2019-05-31 | Journal article
DOI: 10.1016/j.ebiom.2019.05.034
ISSN: 2352-3964
Source: Self-asserted source
Hugo Jimenez
grade
Preferred source (of 2)‎

Use of non-ionizing electromagnetic fields for the treatment of cancer

Frontiers in Bioscience - Landmark
2018 | Journal article
EID:

2-s2.0-85047331784
Contributors: Jimenez, H.; Blackman, C.; Lesser, G.; Debinski, W.; Chan, M.; Sharma, S.; Watabe, K.; Lo, H.-W.; Thomas, A.; Godwin, D. et al.
Source: Self-asserted source
Hugo Jimenez via Scopus - Elsevier

Prevention and treatment of cancer with aspirin: Where do we stand?

Seminars in Oncology
2014 | Journal article
DOI: 10.1053/j.seminoncol.2014.04.012
EID:

2-s2.0-84904193620
Contributors: Pasche, B.; Wang, M.; Pennison, M.; Jimenez, H.
Source: Self-asserted source
Hugo Jimenez via Scopus - Elsevier
grade
Preferred source (of 2)‎

Systemic treatment of cancer with low and safe levels of radiofrequency electromagnetic fields amplitude-modulated at tumor-specific frequencies

Bioelectromagnetic and Subtle Energy Medicine
2014 | Book chapter
Part of DOI: 10.1201/b17978
EID:

2-s2.0-85061278945
Contributors: Pasche, B.; Jimenez, H.; Zimmerman, J.; Pennison, M.; Wang, M.; Posey, J.; Forero-Torres, A.; Carpenter, J.T.; Brezovich, I.; Blackstock, A.W. et al.
Source: Self-asserted source
Hugo Jimenez via Scopus - Elsevier

TGFBR1 and cancer susceptibility

Transactions of the American Clinical and Climatological Association
2014 | Journal article
EID:

2-s2.0-84958689336
Contributors: Pasche, B.; Pennison, M.J.; Jimenez, H.; Wang, M.
Source: Self-asserted source
Hugo Jimenez via Scopus - Elsevier

Targeted treatment of cancer with radiofrequency electromagnetic fields amplitude-modulated at tumor-specific frequencies

Chinese Journal of Cancer
2013 | Journal article
DOI: 10.5732/cjc.013.10177
EID:

2-s2.0-84887341546
Contributors: Zimmerman, J.W.; Jimenez, H.; Pennison, M.J.; Brezovich, I.; Morgan, D.; Mudry, A.; Costa, F.P.; Barbault, A.; Pasche, B.
Source: Self-asserted source
Hugo Jimenez via Scopus - Elsevier
grade
Preferred source (of 2)‎

Tualang honey protects keratinocytes from ultraviolet radiation-induced inflammation and DNA damage.

Photochemistry and photobiology
2012-02-21 | Journal article
DOI: 10.1111/j.1751-1097.2012.01100.x
PMID: 22276569
PMC: PMC3375347
Source: Self-asserted source
Hugo Jimenez

Peer review (1 review for 1 publication/grant)

Review activity for Journal of experimental & clinical cancer research. (1)
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