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Works (15)

Novel Anti-Acanthamoebic Activities of Irosustat and STX140 and Their Nanoformulations

Antibiotics
2023-03-13 | Journal article
DOI: 10.3390/antibiotics12030561
Contributors: Ruqaiyyah Siddiqui; Mutasem Rawas-Qalaji; Mohammed I. El-Gamal; Sreedevi Sajeev; Jayalakshmi Jagal; Seyed-Omar Zaraei; Rawan M. Sbenati; Hanan S. Anbar; Wolfgang Dohle; Barry V. L. Potter et al.
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Synthesis, biological evaluation, and molecular modeling studies of a new series of imidazothiazole or imidazooxazole derivatives as inhibitors of ectonucleoside triphosphate diphosphohydrolases (NTPDases)

Medicinal Chemistry Research
2023-02 | Journal article
DOI: 10.1007/s00044-022-03000-y
Contributors: Mahmoud K. Shehata; Muhammad Uzair; Seyed–Omar Zaraei; Afnan I. Shahin; Syed J. A. Shah; Saif Ullah; Jamshed Iqbal; Mohammed I. El–Gamal
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Imidazothiazole Derivatives Exhibited Potent Effects against Brain-Eating Amoebae

Antibiotics
2022-10-30 | Journal article
DOI: 10.3390/antibiotics11111515
Contributors: Ruqaiyyah Siddiqui; Mohammed El-Gamal; Anania Boghossian; Balsam Saeed; Chang-Hyun Oh; Mohammed Abdel-Maksoud; Ahmad Alharbi; Hasan Alfahemi; Naveed Khan
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Evaluation of Substituted Pyrazole-Based Kinase Inhibitors in One Decade (2011–2020): Current Status and Future Prospects

Molecules
2022-01-05 | Journal article
DOI: 10.3390/molecules27010330
Contributors: Mohammed I. El-Gamal; Seyed-Omar Zaraei; Moustafa M. Madkour; Hanan S. Anbar
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Evaluation of the Inhibitory Effects of Pyridylpyrazole Derivatives on LPS-Induced PGE2 Productions and Nitric Oxide in Murine RAW 264.7 Macrophages

Molecules
2021-10-27 | Journal article
DOI: 10.3390/molecules26216489
Contributors: Mahmoud M. Gamal El-Din; Mohammed I. El-Gamal; Young-Do Kwon; Su-Yeon Kim; Hee-Soo Han; Sang-Eun Park; Chang-Hyun Oh; Kyung-Tae Lee; Hee-Kwon Kim
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Steroid sulfatase inhibitors: the current landscape

Expert Opinion on Therapeutic Patents
2021-06-03 | Journal article
DOI: 10.1080/13543776.2021.1910237
Contributors: Hanan S. Anbar; Zahraa Isa; Jana J. Elounais; Mariam A. Jameel; Joudi H. Zib; Aya M. Samer; Aya F. Jawad; Mohammed I. El-Gamal
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Discovery of New Imidazo[2,1-b]thiazole Derivatives as Potent Pan-RAF Inhibitors with Promising In Vitro and In Vivo Anti-melanoma Activity

Journal of Medicinal Chemistry
2021-05-27 | Journal article
DOI: 10.1021/acs.jmedchem.1c00230
Contributors: Mohammed S. Abdel-Maksoud; Mohammed I. El-Gamal; Bong S. Lee; Mahmoud M. Gamal El-Din; Hong R. Jeon; Dow Kwon; Usama M. Ammar; Karim I. Mersal; Eslam M. H. Ali; Kyung-Tae Lee et al.
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Current status and future prospects of p38α/MAPK14 kinase and its inhibitors

European Journal of Medicinal Chemistry
2021-03 | Journal article
DOI: 10.1016/j.ejmech.2021.113216
Contributors: Moustafa M. Madkour; Hanan S. Anbar; Mohammed I. El-Gamal
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Mechanistic/mammalian target of rapamycin: Recent pathological aspects and inhibitors

Medicinal Research Reviews
2019-03 | Journal article
DOI: 10.1002/med.21535
Contributors: Mohammed S. Abdel‐Maksoud; Mohammed I. El‐Gamal; Dalia Reyane Benhalilou; Sandy Ashraf; Shatha Abdulghaffar Mohammed; Chang‐Hyun Oh
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Design, synthesis, in vitro anticancer evaluation, kinase inhibitory effects, and pharmacokinetic profile of new 1,3,4-triarylpyrazole derivatives possessing terminal sulfonamide moiety

Journal of Enzyme Inhibition and Medicinal Chemistry
2019-01-01 | Journal article
DOI: 10.1080/14756366.2018.1530225
Contributors: Mohammed S. Abdel-Maksoud; Mohammed I. El-Gamal; Mahmoud M. Gamal El-Din; Chang Hyun Oh
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Design, synthesis, in vitro potent antiproliferative activity, and kinase inhibitory effects of new triarylpyrazole derivatives possessing different heterocycle terminal moieties

Journal of Enzyme Inhibition and Medicinal Chemistry
2019-01-01 | Journal article
DOI: 10.1080/14756366.2019.1653292
Contributors: Mahmoud M. Gamal El-Din; Mohammed I. El-Gamal; Mohammed S. Abdel-Maksoud; Kyung Ho Yoo; Chang-Hyun Oh
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Synthesis of New Triarylpyrazole Derivatives Possessing Terminal Sulfonamide Moiety and Their Inhibitory Effects on PGE<sub>2</sub> and Nitric Oxide Productions in Lipopolysaccharide-Induced RAW 264.7 Macrophages

Molecules
2018-10 | Journal article | Author
DOI: 10.3390/molecules23102556
Contributors: Mohammed S. Abdel-Maksoud; Mohammed El-Gamal; Mahmoud M. Gamal El-Din; Yunji Choi; Jungseung Choi; Ji-Sun Shin; Shin-Young Kang; Kyung Ho Yoo; Kyung-Tae Lee; Daejin Baek et al.
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Multidisciplinary Digital Publishing Institute
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Recent Advances of Colony-Stimulating Factor-1 Receptor (CSF-1R) Kinase and Its Inhibitors

Journal of Medicinal Chemistry
2018-07-12 | Journal article
DOI: 10.1021/acs.jmedchem.7b00873
Contributors: Mohammed I. El-Gamal; Shahad K. Al-Ameen; Dania M. Al-Koumi; Mawadda G. Hamad; Nouran A. Jalal; Chang-Hyun Oh
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Pyrrolo[3,2-c]pyridine derivatives with potential inhibitory effect against FMS kinase: in vitro biological studies

Journal of Enzyme Inhibition and Medicinal Chemistry
2018-01-01 | Journal article
DOI: 10.1080/14756366.2018.1491563
Contributors: Mohammed I. El-Gamal; Chang-Hyun Oh
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Tricyclic coumarin sulphonate derivatives with alkaline phosphatase inhibitory effects: in vitro and docking studies

Journal of Enzyme Inhibition and Medicinal Chemistry
2018-01-01 | Journal article
DOI: 10.1080/14756366.2018.1428193
Contributors: Jamshed Iqbal; Mohammed I. El-Gamal; Syeda Abida Ejaz; Joanna Lecka; Jean Sévigny; Chang-Hyun Oh
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Peer review (3 reviews for 2 publications/grants)

Review activity for Journal of medicinal chemistry. (1)
Review activity for Medicinal chemistry research. (2)
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