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Biography
I am a cancer biologist with experience in basic and translational immunooncology. My research is focused on pre-clinical development of therapies that stimulate anti-tumor immunity by inducing “hot”, immune-cell enriched, tumor microenvironment. Currently, my group explores senescence-inducing therapies that activate pro-inflammatory pathways in tumor cells resulting in increased secretion of chemokines that promote immune cell homing into the tumor. We utilize mouse models of melanoma and mammary cancer, as well as patient-derived models, such as patient-derived organoids and patient-derived xenografts grown in humanized mice.
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W81XWH-22-1-0019