Personal information

Activities

Employment (2)

Shenzhen University: Shenzhen, Guangdong, CN

2016-05-12 to present | Professor, Executive Dean (School of Medicine)
Employment
Source: Self-asserted source
Xingzhi Xu

Capital Normal University: Beijing, CN

2005-09-01 to 2016-05-11 | Professor (College of Life Science)
Employment
Source: Self-asserted source
Xingzhi Xu

Works (50 of 102)

Items per page:
Page 1 of 3

MUS81 UFMylation at K400 promotes cell survival in response to camptothecin-induced replication stress

Genome Instability & Disease
2024-07-01 | Journal article
Contributors: Qunsong Tan; Xingzhi Xu
Source: check_circle
Crossref

ULK1-dependent phosphorylation of PKM2 antagonizes O-GlcNAcylation and regulates the Warburg effect in breast cancer

Oncogene
2024-06-07 | Journal article
Contributors: Zibin Zhou; Xiyuan Zheng; Jianxin Zhao; Aiyun Yuan; Zhuan Lv; Guangcan Shao; Bin Peng; Meng-Qiu Dong; Quan Xu; Xingzhi Xu et al.
Source: check_circle
Crossref

RNase P: Beyond Precursor tRNA Processing

Genomics, Proteomics & Bioinformatics
2024-05-09 | Journal article
Contributors: Peipei Wang; Juntao Lin; Xiangyang Zheng; Xingzhi Xu; Jianhua Yang
Source: check_circle
Crossref

Human HELQ regulates DNA end resection at DNA double-strand breaks and stalled replication forks

Nucleic Acids Research
2023-12-11 | Journal article
Contributors: Yuqin Zhao; Kaiping Hou; Youhang Li; Shuailin Hao; Yu Liu; Yinan Na; Chao Li; Jian Cui; Xingzhi Xu; Xiaohua Wu et al.
Source: check_circle
Crossref

Implications of ubiquitination and the maintenance of replication fork stability in cancer therapy

Bioscience Reports
2023-10-31 | Journal article
Contributors: Donghui Xia; Xuefei Zhu; Ying Wang; Peng Gong; Hong-Shu Su; Xingzhi Xu
Source: check_circle
Crossref

ULK1-dependent phosphorylation of PKM2 antagonizes O-GlcNAcylation and inhibits the Warburg effect in breast cancer

2023-09-16 | Preprint
Contributors: Zibin Zhou; Xiyuan Zheng; Jianxin Zhao; Aiyun Yuan; Guangcan Shao; Bin Peng; Meng-Qiu Dong; Quan Xu; Xingzhi Xu; Jing Li
Source: check_circle
Crossref

Regulation of ATR–CHK1 signaling by ubiquitination of CLASPIN

Biochemical Society Transactions
2022-10-31 | Journal article
Contributors: Xuefei Zhu; Xiang-Yang Zheng; Peng Gong; Xingzhi Xu
Source: check_circle
Crossref

Dynamic switching of crotonylation to ubiquitination of H2A at lysine 119 attenuates transcription–replication conflicts caused by replication stress

Nucleic Acids Research
2022-09-23 | Journal article
Contributors: Shuailin Hao; Ya Wang; Yuqin Zhao; Wen Gao; Wei Cui; Youhang Li; Jian Cui; Yu Liu; Lixiu Lin; Xingzhi Xu et al.
Source: check_circle
Crossref

PARP1 and CHK1 coordinate PLK1 enzymatic activity during the DNA damage response to promote homologous recombination-mediated repair

Nucleic Acids Research
2021-07-21 | Journal article
Contributors: Bin Peng; Ruifeng Shi; Jing Bian; Yuwei Li; Peipei Wang; Hailong Wang; Ji Liao; Wei-Guo Zhu; Xingzhi Xu
Source: check_circle
Crossref

Synergy between SIRT1 and SIRT6 helps recognize DNA breaks and potentiates the DNA damage response and repair in humans and mice.

eLife
2020-06 | Journal article
Contributors: Meng F; Qian M; Peng B; Peng L; Wang X; Zheng K; Liu Z; Tang X; Zhang S; Sun S et al.
Source: Self-asserted source
Xingzhi Xu via Europe PubMed Central

HDAC8 cooperates with SMAD3/4 complex to suppress SIRT7 and promote cell survival and migration.

Nucleic acids research
2020-04 | Journal article
Contributors: Tang X; Li G; Su F; Cai Y; Shi L; Meng Y; Liu Z; Sun J; Wang M; Qian M et al.
Source: Self-asserted source
Xingzhi Xu via Europe PubMed Central

GLP-catalyzed H4K16me1 promotes 53BP1 recruitment to permit DNA damage repair and cell survival.

Nucleic acids research
2019-12 | Journal article
Contributors: Lu X; Tang M; Zhu Q; Yang Q; Li Z; Bao Y; Liu G; Hou T; Lv Y; Zhao Y et al.
Source: Self-asserted source
Xingzhi Xu via Europe PubMed Central

Prognostic Significance of FOXC1 in Various Cancers: A Systematic Review and Meta-Analysis.

Molecular diagnosis & therapy
2019-12 | Journal article
Contributors: Sabapathi N; Sabarimurugan S; Madurantakam Royam M; Kumarasamy C; Xu X; Xu G; Jayaraj R
Source: Self-asserted source
Xingzhi Xu via Europe PubMed Central

Synthesis and cytotoxic activity of chalcone analogues containing a thieno[2,3-d]pyrimidin-2-yl group as the A-ring or B-ring.

Bioorganic chemistry
2019-10 | Journal article
Contributors: Wang FC; Peng B; Cao SL; Li HY; Yuan XL; Zhang TT; Shi R; Li Z; Liao J; Wang H et al.
Source: Self-asserted source
Xingzhi Xu via Europe PubMed Central

CD157 Confers Host Resistance to Mycobacterium tuberculosis via TLR2-CD157-PKCzeta-Induced Reactive Oxygen Species Production.

mBio
2019-08 | Journal article
Contributors: Yang Q; Liao M; Wang W; Zhang M; Chen Q; Guo J; Peng B; Huang J; Liu H; Yahagi A et al.
Source: Self-asserted source
Xingzhi Xu via Europe PubMed Central

Chk2-dependent phosphorylation of myosin phosphatase targeting subunit 1 (MYPT1) regulates centrosome maturation.

Cell cycle (Georgetown, Tex.)
2019-08 | Journal article
Contributors: Nai S; Shi Y; Ru H; Ding Y; Geng Q; Li Z; Dong MQ; Xu X; Li J
Source: Self-asserted source
Xingzhi Xu via Europe PubMed Central

C1QBP Promotes Homologous Recombination by Stabilizing MRE11 and Controlling the Assembly and Activation of MRE11/RAD50/NBS1 Complex.

Molecular cell
2019-07 | Journal article
Contributors: Bai Y; Wang W; Li S; Zhan J; Li H; Zhao M; Zhou XA; Li S; Li X; Huo Y et al.
Source: Self-asserted source
Xingzhi Xu via Europe PubMed Central

Cadmium disrupts the DNA damage response by destabilizing RNF168.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
2019-07 | Journal article
Contributors: Zhang S; Hao S; Qiu Z; Wang Y; Zhao Y; Li Y; Gao W; Wu Y; Liu C; Xu X et al.
Source: Self-asserted source
Xingzhi Xu via Europe PubMed Central

MRE11 UFMylation promotes ATM activation.

Nucleic acids research
2019-05 | Journal article
Contributors: Wang Z; Gong Y; Peng B; Shi R; Fan D; Zhao H; Zhu M; Zhang H; Lou Z; Zhou J et al.
Source: Self-asserted source
Xingzhi Xu via Europe PubMed Central

Post-Translational Modifications of the Mini-Chromosome Maintenance Proteins in DNA Replication.

Genes
2019-04 | Journal article
Contributors: Li Z; Xu X
Source: Self-asserted source
Xingzhi Xu via Europe PubMed Central

SIRT7-mediated ATM deacetylation is essential for its deactivation and DNA damage repair.

Science advances
2019-03 | Journal article
Contributors: Tang M; Li Z; Zhang C; Lu X; Tu B; Cao Z; Li Y; Chen Y; Jiang L; Wang H et al.
Source: Self-asserted source
Xingzhi Xu via Europe PubMed Central

RNF126 Quenches RNF168 Function in the DNA Damage Response.

Genomics, proteomics & bioinformatics
2018-12 | Journal article
Contributors: Zhang L; Wang Z; Shi R; Zhu X; Zhou J; Peng B; Xu X
Source: Self-asserted source
Xingzhi Xu via Europe PubMed Central
grade
Preferred source (of 2)‎

PLK1 targets CtIP to promote microhomology-mediated end joining.

Nucleic acids research
2018-11 | Journal article
Contributors: Wang H; Qiu Z; Liu B; Wu Y; Ren J; Liu Y; Zhao Y; Wang Y; Hao S; Li Z et al.
Source: Self-asserted source
Xingzhi Xu via Europe PubMed Central

Synthesis and evaluation of chalcone analogues containing a 4-oxoquinazolin-2-yl group as potential anti-tumor agents.

European journal of medicinal chemistry
2018-11 | Journal article
Contributors: Han X; Peng B; Xiao BB; Sheng-Li Cao; Yang CR; Wang WZ; Wang FC; Li HY; Yuan XL; Shi R et al.
Source: Self-asserted source
Xingzhi Xu via Europe PubMed Central

Destabilization of linker histone H1.2 is essential for ATM activation and DNA damage repair.

Cell research
2018-05 | Journal article
Contributors: Li Z; Li Y; Tang M; Peng B; Lu X; Yang Q; Zhu Q; Hou T; Li M; Liu C et al.
Source: Self-asserted source
Xingzhi Xu via Europe PubMed Central

Synthesis, cytotoxic evaluation and target identification of thieno[2,3-d]pyrimidine derivatives with a dithiocarbamate side chain at C2 position.

European journal of medicinal chemistry
2018-05 | Journal article
Contributors: Yang CR; Peng B; Cao SL; Ren TT; Jiang W; Wang FC; Li YS; Wang G; Li Z; Xu S et al.
Source: Self-asserted source
Xingzhi Xu via Europe PubMed Central

Chk1 modulates the interaction between myosin phosphatase targeting protein 1 (MYPT1) and protein phosphatase 1cβ (PP1cβ).

Cell cycle (Georgetown, Tex.)
2018-03 | Journal article
Contributors: Hu X; Li Z; Ding Y; Geng Q; Xiahou Z; Ru H; Dong MQ; Xu X; Li J
Source: Self-asserted source
Xingzhi Xu via Europe PubMed Central

Checkpoint kinase 1–induced phosphorylation of O-linked β-N-acetylglucosamine transferase regulates the intermediate filament network during cytokinesis

Journal of Biological Chemistry
2017-12 | Journal article
Contributors: Zhe Li; Xueyan Li; Shanshan Nai; Qizhi Geng; Ji Liao; Xingzhi Xu; Jing Li
Source: check_circle
Crossref

Ataxin-10 is involved in Golgi membrane dynamics.

Journal of genetics and genomics = Yi chuan xue bao
2017-11 | Journal article
Contributors: Tian J; Shi Y; Nai S; Geng Q; Zhang L; Wei GH; Xu X; Li J
Source: Self-asserted source
Xingzhi Xu via Europe PubMed Central

The E3 ubiquitin ligase APC/C<sup>C</sup><sup>dh1</sup> degrades MCPH1 after MCPH1-βTrCP2-Cdc25A-mediated mitotic entry to ensure neurogenesis.

The EMBO journal
2017-11 | Journal article
Contributors: Liu X; Zong W; Li T; Wang Y; Xu X; Zhou ZW; Wang ZQ
Source: Self-asserted source
Xingzhi Xu via Europe PubMed Central

Polo-like kinase 1 (PLK1)-dependent phosphorylation of methylenetetrahydrofolate reductase (MTHFR) regulates replication via histone methylation.

Cell cycle (Georgetown, Tex.)
2017-08 | Journal article
Contributors: Li X; Nai S; Ding Y; Geng Q; Zhu B; Yu K; Zhu WG; Dong MQ; Su XD; Xu X et al.
Source: Self-asserted source
Xingzhi Xu via Europe PubMed Central

Aurora kinase B dependent phosphorylation of 53BP1 is required for resolving merotelic kinetochore-microtubule attachment errors during mitosis.

Oncotarget
2017-07 | Journal article
Contributors: Wang H; Peng B; Pandita RK; Engler DA; Matsunami RK; Xu X; Hegde PM; Butler BE; Pandita TK; Mitra S et al.
Source: Self-asserted source
Xingzhi Xu via Europe PubMed Central

G9a coordinates with the RPA complex to promote DNA damage repair and cell survival.

Proceedings of the National Academy of Sciences of the United States of America
2017-07 | Journal article
Contributors: Yang Q; Zhu Q; Lu X; Du Y; Cao L; Shen C; Hou T; Li M; Li Z; Liu C et al.
Source: Self-asserted source
Xingzhi Xu via Europe PubMed Central

Ubiquitin-like modifications in the DNA damage response.

Mutation research
2017-07 | Journal article
Contributors: Wang Z; Zhu WG; Xu X
Source: Self-asserted source
Xingzhi Xu via Europe PubMed Central

Downregulation of SIRT7 by 5-fluorouracil induces radiosensitivity in human colorectal cancer.

Theranostics
2017-03 | Journal article
Contributors: Tang M; Lu X; Zhang C; Du C; Cao L; Hou T; Li Z; Tu B; Cao Z; Li Y et al.
Source: Self-asserted source
Xingzhi Xu via Europe PubMed Central

Phosphorylation of LSD1 by PLK1 promotes its chromatin release during mitosis.

Cell & bioscience
2017-03 | Journal article
Contributors: Peng B; Shi R; Jiang W; Ding YH; Dong MQ; Zhu WG; Xu X
Source: Self-asserted source
Xingzhi Xu via Europe PubMed Central

Microhomology-mediated end joining: new players join the team.

Cell & bioscience
2017-01 | Journal article
Contributors: Wang H; Xu X
Source: Self-asserted source
Xingzhi Xu via Europe PubMed Central

Protein Phosphatase 6 Protects Prophase I-Arrested Oocytes by Safeguarding Genomic Integrity.

PLoS genetics
2016-12 | Journal article
Contributors: Hu MW; Meng TG; Jiang ZZ; Dong MZ; Schatten H; Xu X; Wang ZB; Sun QY
Source: Self-asserted source
Xingzhi Xu via Europe PubMed Central

Synthesis, crystal structures and antitumor activity of two platinum(II) complexes with methyl hydrazinecarbodithioate derivatives of indolin-2-one.

European journal of medicinal chemistry
2016-12 | Journal article
Contributors: Li YS; Peng B; Ma L; Cao SL; Bai LL; Yang CR; Wan CQ; Yan HJ; Ding PP; Li ZF et al.
Source: Self-asserted source
Xingzhi Xu via Europe PubMed Central

TET1 modulates H4K16 acetylation by controlling auto-acetylation of hMOF to affect gene regulation and DNA repair function.

Nucleic acids research
2016-10 | Journal article
Contributors: Zhong J; Li X; Cai W; Wang Y; Dong S; Yang J; Zhang J; Wu N; Li Y; Mao F et al.
Source: Self-asserted source
Xingzhi Xu via Europe PubMed Central

Synthesis and antitumor activity evaluation of quinazoline derivatives bearing piperazine-1-carbodithioate moiety at C4-position.

Bioorganic & medicinal chemistry letters
2016-08 | Journal article
Contributors: Zhang Y; Yang CR; Tang X; Cao SL; Ren TT; Gao M; Liao J; Xu X
Source: Self-asserted source
Xingzhi Xu via Europe PubMed Central

DNA double-strand break repair: a tale of pathway choices.

Acta biochimica et biophysica Sinica
2016-05 | Journal article
Contributors: Li J; Xu X
Source: Self-asserted source
Xingzhi Xu via Europe PubMed Central

UFMylation: A Unique & Fashionable Modification for Life.

Genomics, proteomics & bioinformatics
2016-05 | Journal article
Contributors: Wei Y; Xu X
Source: Self-asserted source
Xingzhi Xu via Europe PubMed Central
grade
Preferred source (of 2)‎

O-GlcNAcylation Antagonizes Phosphorylation of CDH1 (CDC20 Homologue 1).

The Journal of biological chemistry
2016-04 | Journal article
Contributors: Tian J; Geng Q; Ding Y; Liao J; Dong MQ; Xu X; Li J
Source: Self-asserted source
Xingzhi Xu via Europe PubMed Central

Synthesis and biological evaluation of quinazolin-4(3H)-one derivatives bearing dithiocarbamate side chain at C2-position as potential antitumor agents.

European journal of medicinal chemistry
2015-11 | Journal article
Contributors: Ding PP; Gao M; Mao BB; Cao SL; Liu CH; Yang CR; Li ZF; Liao J; Zhao H; Li Z et al.
Source: Self-asserted source
Xingzhi Xu via Europe PubMed Central

Loss of protein phosphatase 6 in oocytes causes failure of meiosis II exit and impaired female fertility.

Journal of cell science
2015-09 | Journal article
Contributors: Hu MW; Wang ZB; Teng Y; Jiang ZZ; Ma XS; Hou N; Cheng X; Schatten H; Xu X; Yang X et al.
Source: Self-asserted source
Xingzhi Xu via Europe PubMed Central

Modulation of LSD1 phosphorylation by CK2/WIP1 regulates RNF168-dependent 53BP1 recruitment in response to DNA damage.

Nucleic acids research
2015-05 | Journal article
Contributors: Peng B; Wang J; Hu Y; Zhao H; Hou W; Zhao H; Wang H; Liao J; Xu X
Source: Self-asserted source
Xingzhi Xu via Europe PubMed Central

Aurora B-dependent phosphorylation of Ataxin-10 promotes the interaction between Ataxin-10 and Plk1 in cytokinesis.

Scientific reports
2015-02 | Journal article
Contributors: Tian J; Tian C; Ding Y; Li Z; Geng Q; Xiahou Z; Wang J; Hou W; Liao J; Dong MQ et al.
Source: Self-asserted source
Xingzhi Xu via Europe PubMed Central

Ago2 facilitates Rad51 recruitment and DNA double-strand break repair by homologous recombination

Cell Research
2014 | Journal article
DOI:

10.1038/cr.2014.36

Contributors: Gao, Min; Wei, Wei; Li, Ming-Ming; Wu, Yong-Sheng; Ba, Zhaoqing; Jin, Kang-Xuan; Li, Miao-Miao; Liao, You-Qi; Adhikari, Samir; Chong, Zechen et al.
Source: Self-asserted source
Xingzhi Xu via ResearcherID

BCL10 regulates RNF8/RNF168-mediated ubiquitination in the DNA damage response

Cell Cycle
2014 | Journal article
DOI:

10.4161/cc.28707

Contributors: Zhao, Hongchang; Zhu, Min; Dou, Gelin; Zhao, Hongli; Zhu, Bingtao; Li, Jing; Liao, Ji; Xu, Xingzhi
Source: Self-asserted source
Xingzhi Xu via ResearcherID
Items per page:
Page 1 of 3

Peer review (4 reviews for 2 publications/grants)

Review activity for Journal of medicinal chemistry. (2)
Review activity for Nature (2)