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Scopus Author ID: 9333122800
ResearcherID: E-3775-2012

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Employment (1)

Karolinska Institutet: Stockholm, SE

(Department of Medical Biochemistry and Biophysics)
Employment
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Karolinska Institutet

Education and qualifications (1)

Karolinska Institutet: Stockholm, Stockholm, SE

2006-03-10 | PhD (MBB)
Education
Source: Self-asserted source
Jens Hjerling Leffler

Works (50 of 68)

Items per page:
Page 1 of 2

Ernest Arenas (1962–2024)

Nature Neuroscience
2024-12 | Journal article
DOI: 10.1038/s41593-024-01797-y
Contributors: Patrik Ernfors; Gonçalo Castelo-Branco; Per Uhlén; Sten Linnarsson; Ulrika Marklund; Jens Hjerling-Leffler; Onur Dagliyan
Source: check_circle
Crossref

Identifying patterns differing between high-dimensional datasets with generalized contrastive PCA

2024-08-09 | Preprint
DOI: 10.1101/2024.08.08.607264
Contributors: Eliezyer Fermino de Oliveira; Pranjal Garg; Jens Hjerling-Leffler; Renata Batista-Brito; Lucas Sjulson
Source: check_circle
Crossref

Transcriptional diversity in synaptic gene sets is sufficient to discriminate cortical neuronal identity

2022-11-25 | Preprint
DOI: 10.1101/2022.11.25.517899
Contributors: Amparo Roig Adam; Jose Martínez López; Sophie van der Spek; Patrick F Sullivan; August B. Smit; Matthijs Verhage; Jens Hjerling-Leffler
Source: check_circle
Crossref

Editorial overview: Rare CNV disorders and neuropsychiatric phenotypes: opportunities, challenges, solutions.

Current opinion in genetics & development
2021-05-28 | Journal article
DOI: 10.1016/j.gde.2021.05.002
PMID: 34059379
Source: Self-asserted source
Jens Hjerling Leffler

A community-based transcriptomics classification and nomenclature of neocortical cell types.

Nature neuroscience
2020-12-01 | Journal article
DOI: 10.1038/s41593-020-0685-8
PMID: 32839617
PMC: PMC7683348
Source: Self-asserted source
Jens Hjerling Leffler

Intrinsic electrophysiological properties predict variability in morphology and connectivity among striatal Parvalbumin-expressing Pthlh-cells.

Scientific reports
2020-09-24 | Journal article
DOI: 10.1038/s41598-020-72588-1
PMID: 32973206
PMC: PMC7518419
Source: Self-asserted source
Jens Hjerling Leffler

Heterogeneous somatostatin-expressing neuron population in mouse ventral tegmental area.

eLife
2020-08-04 | Journal article
DOI: 10.7554/elife.59328
PMID: 32749220
PMC: PMC7440918
Source: Self-asserted source
Jens Hjerling Leffler

Conditional GWAS analysis to identify disorder-specific SNPs for psychiatric disorders.

Molecular psychiatry
2020-05-12 | Journal article
DOI: 10.1038/s41380-020-0705-9
PMID: 32398722
Source: Self-asserted source
Jens Hjerling Leffler

Ghrelin suppresses insulin secretion in human islets and type 2 diabetes patients have diminished islet ghrelin cell number and lower plasma ghrelin levels.

Molecular and cellular endocrinology
2020-05-03 | Journal article
DOI: 10.1016/j.mce.2020.110835
PMID: 32371087
Source: Self-asserted source
Jens Hjerling Leffler

Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson's disease.

Nature genetics
2020-04-27 | Journal article
DOI: 10.1038/s41588-020-0610-9
PMID: 32341526
PMC: PMC7930801
Source: Self-asserted source
Jens Hjerling Leffler

Probabilistic cell typing enables fine mapping of closely related cell types in situ

Nature Methods
2020-01-18 | Journal article
DOI: 10.1038/s41592-019-0631-4
Contributors: Xiaoyan Qian; Kenneth D. Harris; Thomas Hauling; Dimitris Nicoloutsopoulos; Ana B. Muñoz-Manchado; Nathan Skene; Jens Hjerling-Leffler; Mats Nilsson
Source: check_circle
Crossref

Spatiotemporal mapping of RNA editing in the developing mouse brain using in situ sequencing reveals regional and cell-type-specific regulation.

BMC biology
2020-01-14 | Journal article
DOI: 10.1186/s12915-019-0736-3
PMID: 31937309
PMC: PMC6961268
Source: Self-asserted source
Jens Hjerling Leffler

ALK4 coordinates extracellular and intrinsic signals to regulate development of cortical somatostatin interneurons

Journal of Cell Biology
2020-01-06 | Journal article
DOI: 10.1083/jcb.201905002
Contributors: Christina Göngrich; Favio A. Krapacher; Hermany Munguba; Diana Fernández-Suárez; Annika Andersson; Jens Hjerling-Leffler; Carlos F. Ibáñez
Source: check_circle
Crossref

Specialized cutaneous Schwann cells initiate pain sensation

Science
2019-08-16 | Journal article
DOI: 10.1126/science.aax6452
Contributors: Hind Abdo; Laura Calvo-Enrique; Jose Martinez Lopez; Jianren Song; Ming-Dong Zhang; Dmitry Usoskin; Abdeljabbar El Manira; Igor Adameyko; Jens Hjerling-Leffler; Patrik Ernfors
Source: check_circle
Crossref

Transcriptomic correlates of electrophysiological and morphological diversity within and across excitatory and inhibitory neuron classes

PLOS Computational Biology
2019-06-18 | Journal article
DOI: 10.1371/journal.pcbi.1007113
Contributors: Claire Bomkamp; Lyle J. Graham; Shreejoy J. Tripathy; Carolina Bengtsson Gonzales; Jens Hjerling-Leffler; Ann Marie Craig; Paul Pavlidis
Source: check_circle
Crossref

Transcriptomic correlates of electrophysiological and morphological diversity within and across neuron types

2019-01-18 | Other
DOI: 10.1101/524561
Contributors: Claire Bomkamp; Shreejoy Tripathy; Carolina Bengtsson Gonzales; Jens Hjerling Leffler; Ann Marie Craig; Paul Pavlidis
Source: check_circle
Crossref

Biological annotation of genetic loci associated with intelligence in a meta-analysis of 87,740 individuals

Molecular psychiatry
2018 | Journal article
DOI: 10.1038/s41380-018-0040-6
Source: Self-asserted source
Jens Hjerling Leffler

Classes and continua of hippocampal CA1 inhibitory neurons revealed by single-cell transcriptomics

PLoS biology
2018 | Journal article
DOI: 10.1371/journal.pbio.2006387
Source: Self-asserted source
Jens Hjerling Leffler

Diversity of Interneurons in the Dorsal Striatum Revealed by Single-Cell RNA Sequencing and PatchSeq

Cell reports
2018 | Journal article
DOI: 10.1016/j.celrep.2018.07.053
Source: Self-asserted source
Jens Hjerling Leffler

Genetic identification of brain cell types underlying schizophrenia

Nature genetics
2018 | Journal article
DOI: 10.1038/s41588-018-0129-5
Source: Self-asserted source
Jens Hjerling Leffler

Genetic meta-analysis identifies 9 novel loci and functional pathways for Alzheimers disease risk

2018 | Other
DOI: 10.1101/258533
Source: Self-asserted source
Jens Hjerling Leffler

Genome-wide Analysis of Insomnia (N=1,331,010) Identifies Novel Loci and Functional Pathways

2018 | Other
DOI: 10.1101/214973
Source: Self-asserted source
Jens Hjerling Leffler

Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence

Nature genetics
2018 | Journal article
DOI: 10.1038/s41588-018-0152-6
Source: Self-asserted source
Jens Hjerling Leffler

Maternal thyroid hormone is required for parvalbumin neurone development in the anterior hypothalamic area

Journal of neuroendocrinology
2018 | Journal article
DOI: 10.1111/jne.12573
Source: Self-asserted source
Jens Hjerling Leffler

Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways

Nature genetics
2018 | Journal article
DOI: 10.1038/s41588-018-0151-7
Source: Self-asserted source
Jens Hjerling Leffler

Molecular architecture of the mouse nervous system

2018 | Other
DOI: 10.1101/294918
Source: Self-asserted source
Jens Hjerling Leffler

Molecular Architecture of the Mouse Nervous System

Cell
2018 | Journal article
DOI: 10.1016/j.cell.2018.06.021
Source: Self-asserted source
Jens Hjerling Leffler

Prioritizing risk genes for neurodevelopmental disorders using pathway information

2018 | Other
DOI: 10.1101/410100
Source: Self-asserted source
Jens Hjerling Leffler

Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System

Gastroenterology
2018 | Journal article
DOI: 10.1053/j.gastro.2017.10.005
Source: Self-asserted source
Jens Hjerling Leffler

Transcriptional Convergence of Oligodendrocyte Lineage Progenitors during Development

Developmental cell
2018 | Journal article
DOI: 10.1016/j.devcel.2018.07.005
Source: Self-asserted source
Jens Hjerling Leffler

Classes and continua of hippocampal CA1 inhibitory neurons revealed by single-cell transcriptomics

2017 | Other
DOI: 10.1101/143354
Source: Self-asserted source
Jens Hjerling Leffler

Functional consequences of genetic loci associated with intelligence in a meta-analysis of 87,740 individuals

2017 | Other
DOI: 10.1101/170712
Source: Self-asserted source
Jens Hjerling Leffler

Genetic Identification Of Brain Cell Types Underlying Schizophrenia

2017 | Other
DOI: 10.1101/145466
Source: Self-asserted source
Jens Hjerling Leffler

GWAS meta-analysis (N=279,930) identifies new genes and functional links to intelligence

2017 | Other
DOI: 10.1101/184853
Source: Self-asserted source
Jens Hjerling Leffler

GWAS Meta-Analysis of Neuroticism (N=449,484) Identifies Novel Genetic Loci and Pathways

2017 | Other
DOI: 10.1101/184820
Source: Self-asserted source
Jens Hjerling Leffler

Integrated Bayesian analysis of rare exonic variants to identify risk genes for schizophrenia and neurodevelopmental disorders

2017 | Other
DOI: 10.1101/135293
Source: Self-asserted source
Jens Hjerling Leffler

Integrated Bayesian analysis of rare exonic variants to identify risk genes for schizophrenia and neurodevelopmental disorders

Genome medicine
2017 | Journal article
DOI: 10.1186/s13073-017-0497-y
Source: Self-asserted source
Jens Hjerling Leffler

miR-183 cluster scales mechanical pain sensitivity by regulating basal and neuropathic pain genes

Science (New York, N.Y.)
2017 | Journal article
DOI: 10.1126/science.aam7671
Source: Self-asserted source
Jens Hjerling Leffler

Single-cell transcriptomic profiling of progenitors of the oligodendrocyte lineage reveals transcriptional convergence during development

2017 | Other
DOI: 10.1101/186445
Source: Self-asserted source
Jens Hjerling Leffler

BCL11B/CTIP2 is highly expressed in GABAergic interneurons of the mouse somatosensory cortex

Journal of chemical neuroanatomy
2016 | Journal article
DOI: 10.1016/j.jchemneu.2015.12.004
Source: Self-asserted source
Jens Hjerling Leffler
grade
Preferred source (of 2)‎

Disentangling neural cell diversity using single-cell transcriptomics

Nature neuroscience
2016 | Journal article
DOI: 10.1038/nn.4366
Source: Self-asserted source
Jens Hjerling Leffler
grade
Preferred source (of 2)‎

Novel Striatal GABAergic Interneuron Populations Labeled in the 5HT3a(EGFP) Mouse

Cerebral cortex (New York, N.Y. : 1991)
2016 | Journal article
DOI: 10.1093/cercor/bhu179
Source: Self-asserted source
Jens Hjerling Leffler

Oligodendrocyte heterogeneity in the mouse juvenile and adult central nervous system

Science (New York, N.Y.)
2016 | Journal article
DOI: 10.1126/science.aaf6463
Source: Self-asserted source
Jens Hjerling Leffler

Oligodendrocyte heterogeneity in the mouse juvenile and adult central nervous system.

2016-06 | Journal article
PMID: 27284195
Contributors: Marques S; Zeisel A; Codeluppi S; van Bruggen D; Mendanha Falcão A; Xiao L; Li H; Häring M; Hochgerner H; Romanov RA et al.
Source: Self-asserted source
Jens Hjerling Leffler via Europe PubMed Central

Brain structure. Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq

Science (New York, N.Y.)
2015 | Journal article
DOI: 10.1126/science.aaa1934
Source: Self-asserted source
Jens Hjerling Leffler
grade
Preferred source (of 2)‎

Molecular organization of CA1 interneuron classes

2015 | Other
DOI: 10.1101/034595
Source: Self-asserted source
Jens Hjerling Leffler

Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing

Nature neuroscience
2015 | Journal article
DOI: 10.1038/nn.3881
Source: Self-asserted source
Jens Hjerling Leffler
grade
Preferred source (of 3)‎

Efficient expansion and dopaminergic differentiation of human fetal ventral midbrain neural stem cells by midbrain morphogens

Neurobiology of disease
2013 | Journal article
DOI: 10.1016/j.nbd.2012.08.006
Source: Self-asserted source
Jens Hjerling Leffler
grade
Preferred source (of 4)‎

Sticking out of the crowd: the molecular identity and development of cholecystokinin-containing basket cells

The Journal of physiology
2012 | Journal article
DOI: 10.1113/jphysiol.2011.224386
Source: Self-asserted source
Jens Hjerling Leffler
grade
Preferred source (of 5)‎

The origin of neocortical nitric oxide synthase-expressing inhibitory neurons

Frontiers in neural circuits
2012 | Journal article
DOI: 10.3389/fncir.2012.00044
Source: Self-asserted source
Jens Hjerling Leffler
grade
Preferred source (of 4)‎
Items per page:
Page 1 of 2

Peer review (18 reviews for 10 publications/grants)

Review activity for Biological psychiatry global open science. (2)
Review activity for Communications biology. (1)
Review activity for Molecular psychiatry. (1)
Review activity for Nature (2)
Review activity for Nature aging. (1)
Review activity for Nature communications (4)
Review activity for Nature medicine. (1)
Review activity for Nature neuroscience. (4)
Review activity for Nature protocols (1)
Review activity for Review Commons (1)
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