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Works (20)

Precision Oncology Comes of Age: Designing Best-in-Class Small Molecules by Integrating Two Decades of Advances in Chemistry, Target Biology, and Data Science

Cancer Discovery
2023-10-05 | Journal article
Contributors: Darrin D. Stuart; Angel Guzman-Perez; Natasja Brooijmans; Erica L. Jackson; Gregory V. Kryukov; Adam A. Friedman; Axel Hoos
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Data from RAF-Mutant Melanomas Differentially Depend on ERK2 Over ERK1 to Support Aberrant MAPK Pathway Activation and Cell Proliferation

2023-04-03 | Preprint
Contributors: Matthew S. Crowe; Tatiana Zavorotinskaya; Charles F. Voliva; Matthew D. Shirley; Yanqun Wang; David A. Ruddy; Daniel P. Rakiec; Jeffery A. Engelman; Darrin D. Stuart; Alyson K. Freeman
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Data from RAF-Mutant Melanomas Differentially Depend on ERK2 Over ERK1 to Support Aberrant MAPK Pathway Activation and Cell Proliferation

2023-04-03 | Preprint
Contributors: Matthew S. Crowe; Tatiana Zavorotinskaya; Charles F. Voliva; Matthew D. Shirley; Yanqun Wang; David A. Ruddy; Daniel P. Rakiec; Jeffery A. Engelman; Darrin D. Stuart; Alyson K. Freeman
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Crossref

Supplemental Figure S1 from RAF-Mutant Melanomas Differentially Depend on ERK2 Over ERK1 to Support Aberrant MAPK Pathway Activation and Cell Proliferation

2023-04-03 | Preprint
Contributors: Matthew S. Crowe; Tatiana Zavorotinskaya; Charles F. Voliva; Matthew D. Shirley; Yanqun Wang; David A. Ruddy; Daniel P. Rakiec; Jeffery A. Engelman; Darrin D. Stuart; Alyson K. Freeman
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Crossref

Supplemental Figure S1 from RAF-Mutant Melanomas Differentially Depend on ERK2 Over ERK1 to Support Aberrant MAPK Pathway Activation and Cell Proliferation

2023-04-03 | Preprint
Contributors: Matthew S. Crowe; Tatiana Zavorotinskaya; Charles F. Voliva; Matthew D. Shirley; Yanqun Wang; David A. Ruddy; Daniel P. Rakiec; Jeffery A. Engelman; Darrin D. Stuart; Alyson K. Freeman
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Crossref

Supplemental Figure S2 from RAF-Mutant Melanomas Differentially Depend on ERK2 Over ERK1 to Support Aberrant MAPK Pathway Activation and Cell Proliferation

2023-04-03 | Preprint
Contributors: Matthew S. Crowe; Tatiana Zavorotinskaya; Charles F. Voliva; Matthew D. Shirley; Yanqun Wang; David A. Ruddy; Daniel P. Rakiec; Jeffery A. Engelman; Darrin D. Stuart; Alyson K. Freeman
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Crossref

Supplemental Figure S2 from RAF-Mutant Melanomas Differentially Depend on ERK2 Over ERK1 to Support Aberrant MAPK Pathway Activation and Cell Proliferation

2023-04-03 | Preprint
Contributors: Matthew S. Crowe; Tatiana Zavorotinskaya; Charles F. Voliva; Matthew D. Shirley; Yanqun Wang; David A. Ruddy; Daniel P. Rakiec; Jeffery A. Engelman; Darrin D. Stuart; Alyson K. Freeman
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Crossref

Supplemental Figure S3 from RAF-Mutant Melanomas Differentially Depend on ERK2 Over ERK1 to Support Aberrant MAPK Pathway Activation and Cell Proliferation

2023-04-03 | Preprint
Contributors: Matthew S. Crowe; Tatiana Zavorotinskaya; Charles F. Voliva; Matthew D. Shirley; Yanqun Wang; David A. Ruddy; Daniel P. Rakiec; Jeffery A. Engelman; Darrin D. Stuart; Alyson K. Freeman
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Crossref

Supplemental Figure S3 from RAF-Mutant Melanomas Differentially Depend on ERK2 Over ERK1 to Support Aberrant MAPK Pathway Activation and Cell Proliferation

2023-04-03 | Preprint
Contributors: Matthew S. Crowe; Tatiana Zavorotinskaya; Charles F. Voliva; Matthew D. Shirley; Yanqun Wang; David A. Ruddy; Daniel P. Rakiec; Jeffery A. Engelman; Darrin D. Stuart; Alyson K. Freeman
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Crossref

Supplemental Figure S4 from RAF-Mutant Melanomas Differentially Depend on ERK2 Over ERK1 to Support Aberrant MAPK Pathway Activation and Cell Proliferation

2023-04-03 | Preprint
Contributors: Matthew S. Crowe; Tatiana Zavorotinskaya; Charles F. Voliva; Matthew D. Shirley; Yanqun Wang; David A. Ruddy; Daniel P. Rakiec; Jeffery A. Engelman; Darrin D. Stuart; Alyson K. Freeman
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Crossref

Supplemental Figure S4 from RAF-Mutant Melanomas Differentially Depend on ERK2 Over ERK1 to Support Aberrant MAPK Pathway Activation and Cell Proliferation

2023-04-03 | Preprint
Contributors: Matthew S. Crowe; Tatiana Zavorotinskaya; Charles F. Voliva; Matthew D. Shirley; Yanqun Wang; David A. Ruddy; Daniel P. Rakiec; Jeffery A. Engelman; Darrin D. Stuart; Alyson K. Freeman
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Crossref

Supplemental Figure S5 from RAF-Mutant Melanomas Differentially Depend on ERK2 Over ERK1 to Support Aberrant MAPK Pathway Activation and Cell Proliferation

2023-04-03 | Preprint
Contributors: Matthew S. Crowe; Tatiana Zavorotinskaya; Charles F. Voliva; Matthew D. Shirley; Yanqun Wang; David A. Ruddy; Daniel P. Rakiec; Jeffery A. Engelman; Darrin D. Stuart; Alyson K. Freeman
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Crossref

Supplemental Figure S5 from RAF-Mutant Melanomas Differentially Depend on ERK2 Over ERK1 to Support Aberrant MAPK Pathway Activation and Cell Proliferation

2023-04-03 | Preprint
Contributors: Matthew S. Crowe; Tatiana Zavorotinskaya; Charles F. Voliva; Matthew D. Shirley; Yanqun Wang; David A. Ruddy; Daniel P. Rakiec; Jeffery A. Engelman; Darrin D. Stuart; Alyson K. Freeman
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Crossref

Supplemental Figure S6 from RAF-Mutant Melanomas Differentially Depend on ERK2 Over ERK1 to Support Aberrant MAPK Pathway Activation and Cell Proliferation

2023-04-03 | Preprint
Contributors: Matthew S. Crowe; Tatiana Zavorotinskaya; Charles F. Voliva; Matthew D. Shirley; Yanqun Wang; David A. Ruddy; Daniel P. Rakiec; Jeffery A. Engelman; Darrin D. Stuart; Alyson K. Freeman
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Crossref

Supplemental Figure S6 from RAF-Mutant Melanomas Differentially Depend on ERK2 Over ERK1 to Support Aberrant MAPK Pathway Activation and Cell Proliferation

2023-04-03 | Preprint
Contributors: Matthew S. Crowe; Tatiana Zavorotinskaya; Charles F. Voliva; Matthew D. Shirley; Yanqun Wang; David A. Ruddy; Daniel P. Rakiec; Jeffery A. Engelman; Darrin D. Stuart; Alyson K. Freeman
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Crossref

Supplementary Legends from RAF-Mutant Melanomas Differentially Depend on ERK2 Over ERK1 to Support Aberrant MAPK Pathway Activation and Cell Proliferation

2023-04-03 | Preprint
Contributors: Matthew S. Crowe; Tatiana Zavorotinskaya; Charles F. Voliva; Matthew D. Shirley; Yanqun Wang; David A. Ruddy; Daniel P. Rakiec; Jeffery A. Engelman; Darrin D. Stuart; Alyson K. Freeman
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Crossref

Supplementary Legends from RAF-Mutant Melanomas Differentially Depend on ERK2 Over ERK1 to Support Aberrant MAPK Pathway Activation and Cell Proliferation

2023-04-03 | Preprint
Contributors: Matthew S. Crowe; Tatiana Zavorotinskaya; Charles F. Voliva; Matthew D. Shirley; Yanqun Wang; David A. Ruddy; Daniel P. Rakiec; Jeffery A. Engelman; Darrin D. Stuart; Alyson K. Freeman
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Crossref

Supplementary Tables 1-3 from RAF-Mutant Melanomas Differentially Depend on ERK2 Over ERK1 to Support Aberrant MAPK Pathway Activation and Cell Proliferation

2023-04-03 | Preprint
Contributors: Matthew S. Crowe; Tatiana Zavorotinskaya; Charles F. Voliva; Matthew D. Shirley; Yanqun Wang; David A. Ruddy; Daniel P. Rakiec; Jeffery A. Engelman; Darrin D. Stuart; Alyson K. Freeman
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Crossref

Supplementary Tables 1-3 from RAF-Mutant Melanomas Differentially Depend on ERK2 Over ERK1 to Support Aberrant MAPK Pathway Activation and Cell Proliferation

2023-04-03 | Preprint
Contributors: Matthew S. Crowe; Tatiana Zavorotinskaya; Charles F. Voliva; Matthew D. Shirley; Yanqun Wang; David A. Ruddy; Daniel P. Rakiec; Jeffery A. Engelman; Darrin D. Stuart; Alyson K. Freeman
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Crossref

RAF-Mutant Melanomas Differentially Depend on ERK2 Over ERK1 to Support Aberrant MAPK Pathway Activation and Cell Proliferation

Molecular Cancer Research
2021-06-01 | Journal article
Contributors: Matthew S. Crowe; Tatiana Zavorotinskaya; Charles F. Voliva; Matthew D. Shirley; Yanqun Wang; David A. Ruddy; Daniel P. Rakiec; Jeffery A. Engelman; Darrin D. Stuart; Alyson K. Freeman
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Crossref

Peer review (1 review for 1 publication/grant)

Review activity for Nature chemical biology. (1)