Personal information

protein engineering, directed evolution, biocatalysis, oxidoreductases, P450, ene-reductases, iron dependend halogenases

Activities

Employment (1)

Philipps-Universität Marburg Fachbereich Chemie: Marburg, Hessen, DE

2014-01-01 to 2019-12-31 | Group Leader (Chemical Biology)
Employment
Source: Self-asserted source
Sabrina Hoebenreich

Works (15)

Pervasive cooperative mutational effects on multiple catalytic enzyme traits emerge via long-range conformational dynamics

Nature Communications
2021-03-12 | Journal article
Contributors: Carlos G. Acevedo-Rocha; Aitao Li; Lorenzo D’Amore; Sabrina Hoebenreich; Joaquin Sanchis; Paul Lubrano; Matteo P. Ferla; Marc Garcia-Borràs; Sílvia Osuna; Manfred T. Reetz
Source: check_circle
Crossref

Pervasive cooperative mutational effects on multiple catalytic enzyme traits emerge via long-range conformational dynamics

2020-04-16 | Preprint
Contributors: Carlos G. Acevedo-Rocha; Aitao Li; Lorenzo D’Amore; Sabrina Hoebenreich; Joaquin Sanchis; Paul Lubrano; Matteo P. Ferla; Marc Garcia-Borràs; Sílvia Osuna; Manfred T. Reetz
Source: check_circle
Crossref

Directed Evolution of an FeII-Dependent Halogenase for Asymmetric C(sp3)–H Chlorination

ACS Catalysis
2020-01-17 | Journal article
Contributors: Sabine Duewel; Luca Schmermund; Tabea Faber; Klaus Harms; Vasundara Srinivasan; Eric Meggers; Sabrina Hoebenreich
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Crossref

Directed Evolution of an Feᴵᴵ-Dependent Halogenase for Asymmetric C(sp³)-H Chlorination

2019-11-05 | Other
Contributors: Sabine Duewel; Luca Schmermund; Tabea Faber; Klaus Harms; Vasundara Srinivasan; Eric Meggers; Sabrina Hoebenreich
Source: check_circle
Crossref

P450-Catalyzed Regio- and Diastereoselective Steroid Hydroxylation: Efficient Directed Evolution Enabled by Mutability Landscaping

ACS Catalysis
2018-04-06 | Journal article
Contributors: Carlos G. Acevedo-Rocha; Charles G. Gamble; Richard Lonsdale; Aitao Li; Nathalie Nett; Sabrina Hoebenreich; Julia B. Lingnau; Cornelia Wirtz; Christophe Fares; Heike Hinrichs et al.
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Crossref

Revealing Additional Stereocomplementary Pairs of Old Yellow Enzymes by Rational Transfer of Engineered Residues

ChemBioChem
2017-04-04 | Journal article
Contributors: Nathalie Nett; Sabine Duewel; Alexandra Annelis Richter; Sabrina Hoebenreich
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Crossref

Bioorthogonal Enzymatic Activation of Caged Compounds

Angewandte Chemie International Edition
2015 | Journal article
Source: Self-asserted source
Sabrina Hoebenreich

Bioorthogonale enzymatische Aktivierung maskierter Verbindungen

Angewandte Chemie
2015 | Journal article
Source: Self-asserted source
Sabrina Hoebenreich

Iterative Saturation Mutagenesis: A Powerful Approach to Engineer Proteins by Systematically Simulating Darwinian Evolution

Directed Evolution Library Creation
2014 | Book chapter
Source: Self-asserted source
Sabrina Hoebenreich

Speeding up Directed Evolution: Combining the Advantages of Solid-Phase Combinatorial Gene Synthesis with Statistically Guided Reduction of Screening Effort

ACS Synthetic Biology
2014 | Journal article
Source: Self-asserted source
Sabrina Hoebenreich

Protein Engineering: Development of Novel Enzymes for the Improved Reduction of C=C Double Bonds

Synthetic Methods for Biologically Active Molecules
2013 | Book chapter
Source: Self-asserted source
Sabrina Hoebenreich

Reducing Codon Redundancy and Screening Effort of Combinatorial Protein Libraries Created by Saturation Mutagenesis

Acs Synthetic Biology
2013 | Journal article
DOI:

10.1021/sb300037w

Part of ISSN:

2161-5063

Contributors: Kille, Sabrina; Acevedo-Rocha, Carlos G.; Parra, Loreto P.; Zhang, Zhi-Gang; Opperman, Diederik J.; Reetz, Manfred T.; Pablo Acevedo, Juan
Source: Self-asserted source
Sabrina Hoebenreich via ResearcherID

Regio- and stereoselectivity of P450-catalysed hydroxylation of steroids controlled by laboratory evolution

Nature Chemistry
2011 | Journal article
DOI:

10.1038/NCHEM.1113

Part of ISSN:

1755-4330

Contributors: Kille, Sabrina; Zilly, Felipe E.; Acevedo, Juan P.; Reetz, Manfred T.
Source: Self-asserted source
Sabrina Hoebenreich via ResearcherID

Directed Evolution of an Enantioselective Enoate-Reductase: Testing the Utility of Iterative Saturation Mutagenesis

Advanced Synthesis & Catalysis
2009 | Journal article
Source: Self-asserted source
Sabrina Hoebenreich
grade
Preferred source (of 2)‎

Improved PCR method for the creation of saturation mutagenesis libraries in directed evolution: application to difficult-to-amplify templates

Applied Microbiology and Biotechnology
2008 | Journal article
DOI:

10.1007/s00253-008-1678-9

Part of ISSN:

0175-7598

Contributors: Sanchis, Joaquin; Fernandez, Layla; Carballeira, J. Daniel; Drone, Jullien; Gumulya, Yosephine; Hoebenreich, Horst; Kahakeaw, Daniel; Kille, Sabrina; Lohmer, Renate; Peyralans, Jerome J. -P. et al.
Source: Self-asserted source
Sabrina Hoebenreich via ResearcherID

Peer review (1 review for 1 publication/grant)

Review activity for ACS catalysis. (1)