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Employment (4)

University of California, Santa Cruz: Santa Cruz, CA, US

2019-02-15 to present | Staff scientist (Department of Chemistry and Biochemistry)
Employment
Source: Self-asserted source
Gerd Armin Müller

Universität Leipzig: Leipzig, Sachsen, DE

2008-04-01 to 2019-02-14 | Research Fellow; Deputy Lab Head (Medical School)
Employment
Source: Self-asserted source
Gerd Armin Müller

University of California Santa Cruz: Santa Cruz, CA, US

2016-10-04 to 2017-03-31 | Visiting Scientist (Department of Chemistry and Biochemistry)
Employment
Source: Self-asserted source
Gerd Armin Müller

National Institute on Aging Intramural Research Program: Baltimore, MD, US

2007-06 to 2008-04 | Postdoctoral Researcher (Laboratory of Cardiovascular Science)
Employment
Source: Self-asserted source
Gerd Armin Müller

Education and qualifications (4)

Leipzig University: Leipzig, Sachsen, DE

2014-01-01 to 2019-01-14 | Habilitation (Faculty of Life Sciences)
Qualification
Source: Self-asserted source
Gerd Armin Müller

Universität Leipzig: Leipzig, Sachsen, DE

2004-01 to 2007-05 | Dr. rer. nat. (Ph.D.) (Department of Internal Medicine)
Education
Source: Self-asserted source
Gerd Armin Müller

Universität Leipzig: Leipzig, Sachsen, DE

1998-09 to 2003-12 | Diploma degree (equivalent to M.Sc.) (Faculty of Biosciences, Pharmacy and Psychology)
Education
Source: Self-asserted source
Gerd Armin Müller

Friedrich-Schiller-Universität Jena: Jena, Thüringen, DE

2000-10 to 2001-03 | Diploma degree (equivalent to M.Sc.) (Institute of Microbiology)
Education
Source: Self-asserted source
Gerd Armin Müller

Funding (1)

Mechanisms of cell cycle-dependent transcriptional regulation by MuvB complexes

Source: Self-asserted source
Gerd Armin Müller via DimensionsWizard

Works (31)

HDAC activity is dispensable for repression of cell-cycle genes by DREAM and E2F:RB complexes

Nature Communications
2024-05-24 | Journal article | Author
Part of ISSN: 2041-1723
Contributors: Alison K Barrett; Manisha Arkile-Shingare; Andreas Rechtsteiner; Kelsie M. Rodriguez; Quynh Le; Tilini; Corbin E. Mitchell; Miles W. Membreno; Seth Rubin; Gerd Armin Müller
Source: Self-asserted source
Gerd Armin Müller

Structure and function of MuvB complexes

Oncogene
2022 | Journal article
Contributors: Mueller, Gerd A.; Asthana, Anushweta; Rubin, Seth M.
Source: check_circle
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Preferred source (of 2)‎

Cyclin-dependent kinase-mediated phosphorylation and the negative regulatory domain of transcription factor B-Myb modulate its DNA binding.

The Journal of biological chemistry
2022-08-01 | Journal article
Contributors: Gerd Armin Müller
Source: Self-asserted source
Gerd Armin Müller

Coordinating gene expression during the cell cycle

Trends in Biochemical Sciences
2022-07 | Journal article
Part of ISSN: 0968-0004
Source: Self-asserted source
Gerd Armin Müller

Structural basis for tunable affinity and specificity of LxCxE-dependent protein interactions with the retinoblastoma protein family

Structure
2022-06 | Journal article
Part of ISSN: 0969-2126
Source: Self-asserted source
Gerd Armin Müller

The MuvB complex binds and stabilizes nucleosomes downstream of the transcription start site of cell-cycle dependent genes.

Nature communications
2022-01-26 | Journal article
Source: Self-asserted source
Gerd Armin Müller

Ki-67 gene expression

Cell Death and Differentiation
2021 | Journal article
Contributors: Uxa, Sigrid; Castillo-Binder, Paola; Kohler, Robin; Stangner, Konstanze; Mueller, Gerd A.; Engeland, Kurt
Source: check_circle
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Preferred source (of 2)‎

DNA Affinity Purification: A Pulldown Assay for Identifying and Analyzing Proteins Binding to Nucleic Acids.

Methods in molecular biology (Clifton, N.J.)
2021-03-31 | Book chapter
Source: Self-asserted source
Gerd Armin Müller

The Role of lncRNAs TAPIR-1 and -2 as Diagnostic Markers and Potential Therapeutic Targets in Prostate Cancer

Cancers
2020-04-30 | Journal article
Part of ISSN: 2072-6694
Source: Self-asserted source
Gerd Armin Müller

DREAM and RB cooperate to induce gene repression and cell-cycle arrest in response to p53 activation.

Nucleic Acids Research
2019-08-10 | Journal article
Source: Self-asserted source
Gerd Armin Müller

NAD metabolites interfere with proliferation and functional properties of THP-1 cells

Innate Immunity
2019-07 | Journal article
Part of ISSN: 1753-4259
Part of ISSN: 1753-4267
Source: Self-asserted source
Gerd Armin Müller

The DREAM complex through its subunit Lin37 cooperates with Rb to initiate quiescence.

eLife
2017-09 | Journal article
Source: Self-asserted source
Gerd Armin Müller via Europe PubMed Central

Cell cycle transcription control: DREAM/MuvB and RB-E2F complexes.

Critical reviews in biochemistry and molecular biology
2017-08 | Journal article
Source: Self-asserted source
Gerd Armin Müller via Europe PubMed Central

Timing of transcription during the cell cycle: Protein complexes binding to E2F, E2F/CLE, CDE/CHR, or CHR promoter elements define early and late cell cycle gene expression.

2016-07 | Journal article
Contributors: Müller GA; Stangner K; Schmitt T; Wintsche A; Engeland K
Source: Self-asserted source
Gerd Armin Müller via Europe PubMed Central

The CHR site: definition and genome-wide identification of a cell cycle transcriptional element.

2014 | Journal article
Contributors: Müller GA; Wintsche A; Stangner K; Prohaska SJ; Stadler PF; Engeland K
Source: Self-asserted source
Gerd Armin Müller via Europe PubMed Central

Proteome analysis of the HIV-1 Gag interactome.

2014-07 | Journal article
Contributors: Engeland CE; Brown NP; Börner K; Schümann M; Krause E; Kaderali L; Müller GA; Kräusslich HG
Source: Self-asserted source
Gerd Armin Müller via Europe PubMed Central

Polo-like kinase 4 transcription is activated via CRE and NRF1 elements, repressed by DREAM through CDE/CHR sites and deregulated by HPV E7 protein.

2014-01 | Journal article
Contributors: Fischer M; Quaas M; Wintsche A; Müller GA; Engeland K
Source: Self-asserted source
Gerd Armin Müller via Europe PubMed Central

The forkhead transcription factor FOXM1 controls cell cycle-dependent gene expression through an atypical chromatin binding mechanism.

2013-01 | Journal article
Contributors: Chen X; Müller GA; Quaas M; Fischer M; Han N; Stutchbury B; Sharrocks AD; Engeland K
Source: Self-asserted source
Gerd Armin Müller via Europe PubMed Central

Human ESC/iPSC-based "Omics" and Bioinformatics for Translational Research.

2012 | Journal article
Contributors: Müller G; Tarasov KV; Gundry RL; Boheler KR
Source: Self-asserted source
Gerd Armin Müller via Europe PubMed Central

p53 can repress transcription of cell cycle genes through a p21(WAF1/CIP1)-dependent switch from MMB to DREAM protein complex binding at CHR promoter elements.

2012-12 | Journal article
Contributors: Quaas M; Müller GA; Engeland K
Source: Self-asserted source
Gerd Armin Müller via Europe PubMed Central

Allele-specific siRNA knockdown as a personalized treatment strategy for vascular Ehlers-Danlos syndrome in human fibroblasts.

2012-02 | Journal article
Contributors: Müller GA; Hansen U; Xu Z; Griswold B; Talan MI; McDonnell NB; Briest W
Source: Self-asserted source
Gerd Armin Müller via Europe PubMed Central

The CHR promoter element controls cell cycle-dependent gene transcription and binds the DREAM and MMB complexes.

2012-02 | Journal article
Contributors: Müller GA; Quaas M; Schümann M; Krause E; Padi M; Fischer M; Litovchick L; DeCaprio JA; Engeland K
Source: Self-asserted source
Gerd Armin Müller via Europe PubMed Central

The cellular protein lyric interacts with HIV-1 Gag.

2011-12 | Journal article
Contributors: Engeland CE; Oberwinkler H; Schümann M; Krause E; Müller GA; Kräusslich HG
Source: Self-asserted source
Gerd Armin Müller via Europe PubMed Central

The haploinsufficient Col3a1 mouse as a model for vascular Ehlers-Danlos syndrome.

2010-11 | Journal article
Contributors: Cooper TK; Zhong Q; Krawczyk M; Tae HJ; Müller GA; Schubert R; Myers LA; Dietz HC; Talan MI; Briest W
Source: Self-asserted source
Gerd Armin Müller via Europe PubMed Central

The retinal dehydrogenase/reductase retSDR1/DHRS3 gene is activated by p53 and p63 but not by mutants derived from tumors or EEC/ADULT malformation syndromes.

2010-06 | Journal article
Contributors: Kirschner RD; Rother K; Müller GA; Engeland K
Source: Self-asserted source
Gerd Armin Müller via Europe PubMed Central

The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription.

2010-02 | Journal article
Contributors: Müller GA; Engeland K
Source: Self-asserted source
Gerd Armin Müller via Europe PubMed Central

Transcriptional activation of the tumor suppressor and differentiation gene S100A2 by a novel p63-binding site.

2008-05 | Journal article
Contributors: Kirschner RD; Sänger K; Müller GA; Engeland K
Source: Self-asserted source
Gerd Armin Müller via Europe PubMed Central

Trastuzumab therapy vs tetracycline controlled ERBB2 downregulation: influence on tumour development in an ERBB2-dependent mouse tumour model.

2008-05 | Journal article
Contributors: Hermes M; Schormann W; Brulport M; Uhlemann K; Lupatsch F; Horn LC; Schumann A; Allgaier C; Weishaupt M; Engeland K et al.
Source: Self-asserted source
Gerd Armin Müller via Europe PubMed Central

Expression of cyclin-dependent kinase subunit 1 (Cks1) is regulated during the cell cycle by a CDE/CHR tandem element and is downregulated by p53 but not by p63 or p73.

2007-04 | Journal article
Contributors: Rother K; Li YY; Tschöp K; Kirschner R; Müller GA; Mössner J; Engeland K
Source: Self-asserted source
Gerd Armin Müller via Europe PubMed Central

Chimpanzee, orangutan, mouse, and human cell cycle promoters exempt CCAAT boxes and CHR elements from interspecies differences.

2007-03 | Journal article
Contributors: Müller GA; Heissig F; Engeland K
Source: Self-asserted source
Gerd Armin Müller via Europe PubMed Central

Human cyclin B3. mRNA expression during the cell cycle and identification of three novel nonclassical nuclear localization signals.

2006-04 | Journal article
Contributors: Tschöp K; Müller GA; Grosche J; Engeland K
Source: Self-asserted source
Gerd Armin Müller via Europe PubMed Central

Peer review (17 reviews for 10 publications/grants)

Review activity for Biomedicines. (3)
Review activity for Cancers. (4)
Review activity for Cell death and differentiation. (1)
Review activity for Experimental cell research. (1)
Review activity for Healthcare. (1)
Review activity for Nature communications (2)
Review activity for Pharmaceutics. (1)
Review activity for PloS one. (2)
Review activity for Review Commons (1)
Review activity for Stem cell reviews. (1)