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MedUniGraz - Researcher profile

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Scopus Author ID: 56684773900

Countries

Austria

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Employment (6)

Medical University of Graz: Graz, AT

2023 to present | Tenure Track Assistant Professor & Group Leader (Department of Cardiology)
Employment
Source: Self-asserted source
Mahmoud Abdellatif

Institut Gustave-Roussy: Paris, FR

2020 to 2033 | Postdoctoral Fellow (U1138 - Metabolomics and Cell Biology Platforms)
Employment
Source: Self-asserted source
Mahmoud Abdellatif

Centre de Recherche des Cordeliers: Paris, FR

2020 to 2023 | Postdoctoral Fellow (U1138)
Employment
Source: Self-asserted source
Mahmoud Abdellatif

Medical University of Graz: Graz, Steiermark, AT

2019 to 2020 | Postdoctoral Fellow (Department of Cardiology)
Employment
Source: Self-asserted source
Mahmoud Abdellatif

Medical University of Graz: Graz, Steiermark, AT

2015 to 2019 | PhD Candidate/Reseacher (Department of Cardiology)
Employment
Source: Self-asserted source
Mahmoud Abdellatif

Faculty of Medicine, University of Porto: Porto, PT

2013 to 2015 | Research Fellow (Department of Physiology and Cardiothoracic Surgery)
Employment
Source: Self-asserted source
Mahmoud Abdellatif

Education and qualifications (3)

University of Oxford: Oxford, GB

2021 to 2023 | MSc in Clinical Trials (Population Health)
Education
Source: Self-asserted source
Mahmoud Abdellatif

Medical University of Graz: Graz, Steiermark, AT

2019 | PhD Molecular Medicine (Department of Cardiology)
Education
Source: Self-asserted source
Mahmoud Abdellatif

Faculdade de Medicina da Universidade do Porto: Porto, PT

2015 | MSc Cardiovascular Pathophysiology (Department of physiology and cardiothoracic surgery)
Education
Source: Self-asserted source
Mahmoud Abdellatif

Professional activities (17)

ESC Working Group Myocardial Function: Sophia Antipolis, FR

2022 to present | Nucleus Member and Communication Coordinator
Service
Source: Self-asserted source
Mahmoud Abdellatif

German Cardiac Society: Düsseldorf, DE

2023 | Oskar Lapp Research Prize
Distinction
Source: Self-asserted source
Mahmoud Abdellatif

Joint Heart Failure Meeting of the German, Austrian and Swiss Cardiology Societies: Graz, AT

2022 | Richard Pacher Award for exceptional publications in heart failure research
Distinction
Source: Self-asserted source
Mahmoud Abdellatif

European Society of Cardiology: Sophia Antipolis, FR

2019-08 to 2022 | Young Cardiovascular Professionals Board Committee
Service
Source: Self-asserted source
Mahmoud Abdellatif

ESC Scientists of Tomorrow (SoT): Sophia Antipolis, FR

2019-01 to 2021-12 | Nucleus member
Service
Source: Self-asserted source
Mahmoud Abdellatif

German Cardiac Society: Düsseldorf, DE

2021 | Forschungspreis der AG 23 Herz und Diabetes
Distinction
Source: Self-asserted source
Mahmoud Abdellatif

European Society of Cardiology: Sophia Antipolis, FR

2021 | Young investigator Award (runner-up); Heart Failure Association Winter Meeting
Distinction
Source: Self-asserted source
Mahmoud Abdellatif

European Society of Cardiology: Sophia Antipolis, FR

2020 | Guido Tarone Award; Best Abstract (Heart Failure Association)
Distinction
Source: Self-asserted source
Mahmoud Abdellatif

Medical University of Graz Heart Center: Graz, AT

2019 | Graz Cardio Summit Best Poster Prize
Distinction
Source: Self-asserted source
Mahmoud Abdellatif

Austrian Society of Cardiology: Vienna, AT

2019 | Best Abstract Award
Distinction
Source: Self-asserted source
Mahmoud Abdellatif

Sanofi-Aventis GmbH: Wien, Wien, AT

2017 | Forschungspreis (Best Paper Award)
Distinction
Source: Self-asserted source
Mahmoud Abdellatif

ESC Heart Failure Association: Sophia Antipolis, FR

2017 | Congress Grant
Distinction
Source: Self-asserted source
Mahmoud Abdellatif

ESC Heart Failure Association: Les Diablerets, CH

2017 | Young Investigator Award (HFA Winter Meeting)
Distinction
Source: Self-asserted source
Mahmoud Abdellatif

Austrian Society of Cardiology: Vienna, AT

2017 | Best Paper Award (first author)
Distinction
Source: Self-asserted source
Mahmoud Abdellatif

Medical University of Graz: GRAZ, AT

2017 | Best Presentation Award of the University's Doctoral Day
Distinction
Source: Self-asserted source
Mahmoud Abdellatif

Medical University of Graz: Graz, AT

2016 | Best Presentation Award of the University's Doctoral Day
Distinction
Source: Self-asserted source
Mahmoud Abdellatif

European Society of Cardiology : Sophia Antipolis, FR

2016 | Congress Educational Grant
Distinction
Source: Self-asserted source
Mahmoud Abdellatif

Funding (6)

ÖKG Presidential Research Grant

2020 to 2022 | Grant
Austrian Society of Cardiology (Vienna, AT)
Source: Self-asserted source
Mahmoud Abdellatif

Basic Science Fellowship

2019 to 2019 | Grant
European Society Of Cardiology (Sophia Antipolis, FR)
Source: Self-asserted source
Mahmoud Abdellatif

Staff mobility grant; Cardiovascular R&D unit, Porto Faculty of Medicine (Portugal)

2017-10 to 2017-10 | Grant
Medical University of Graz; Erasmus+ framework (Graz, AT)
Source: Self-asserted source
Mahmoud Abdellatif

Staff mobility grant; Bayer Pharmaceuticals R&D Center (Wuppertal, Germany)

2017-04 to 2017-04 | Grant
Medical University of Graz; Erasmus+ framework (Graz, AT)
Source: Self-asserted source
Mahmoud Abdellatif

PhD Fellowship (FWF standalone project: Cardioprotective Mechanisms of Spermidine

2015 to 2019 | Contract
Austrian Science Fund (graz, AT)
Source: Self-asserted source
Mahmoud Abdellatif

Research/Master's Fellowship (EU-FP7 project; The MEtabolic Road to DIAstolic Heart Failure)

2013 to 2015 | Salary award
European Union (Brussels, BE)
Source: Self-asserted source
Mahmoud Abdellatif

Works (39)

Obesity Accelerates Cardiovascular Ageing

2025-03-21 | Other
DOI: 10.1093/eurheartj/ehaf216
Contributors: Mahmoud Abdellatif; Celia Ruperez; Frank Madeo; Rafael de Cabo; Guido Kroemer
Source: check_circle
Crossref

Autophagy is required for the therapeutic effects of the NAD+ precursor nicotinamide in obesity-related heart failure with preserved ejection fraction

European Heart Journal
2025-02-25 | Journal article
DOI: 10.1093/eurheartj/ehaf062
Contributors: Mahmoud Abdellatif; Francisco Vasques-Nóvoa; Viktoria Trummer-Herbst; Sylvère Durand; Franziska Koser; Moydul Islam; Jihoon Nah; Eun-Ah Sung; Ruli Feng; Fanny Aprahamian et al.
Source: check_circle
Crossref

The ESC Working Group on Myocardial Function

European Heart Journal
2025-02-18 | Journal article
DOI: 10.1093/eurheartj/ehae016
Contributors: Mahmoud Abdellatif; Wolfgang A Linke; Dana K Dawson; Peter P Rainer; Carlo G Tocchetti
Source: check_circle
Crossref

A surge in endogenous spermidine is essential for rapamycin-induced autophagy and longevity

Autophagy
2024-12 | Journal article
DOI: 10.1080/15548627.2024.2396793
Contributors: Sebastian J. Hofer; Ioanna Daskalaki; Mahmoud Abdellatif; Ulrich Stelzl; Simon Sedej; Nektarios Tavernarakis; Guido Kroemer; Frank Madeo
Source: check_circle
Crossref

Spermidine is essential for fasting-mediated autophagy and longevity

Nature Cell Biology
2024-09 | Journal article
DOI: 10.1038/s41556-024-01468-x
Contributors: Sebastian J. Hofer; Ioanna Daskalaki; Martina Bergmann; Jasna Friščić; Andreas Zimmermann; Melanie I. Mueller; Mahmoud Abdellatif; Raffaele Nicastro; Sarah Masser; Sylvère Durand et al.
Source: check_circle
Crossref

Anti-ageing interventions for the treatment of cardiovascular disease

Cardiovascular Research
2024-08-22 | Journal article
DOI: 10.1093/cvr/cvae177
Contributors: Mahmoud Abdellatif; Sophie T Schmid; Alexander Fuerlinger; Guido Kroemer
Source: check_circle
Crossref

Metabolic control of mitophagy

European Journal of Clinical Investigation
2024-04 | Journal article
DOI: 10.1111/eci.14138
Contributors: Andreas Zimmermann; Frank Madeo; Abhinav Diwan; Junichi Sadoshima; Simon Sedej; Guido Kroemer; Mahmoud Abdellatif
Source: check_circle
Crossref

Actionable autophagy checkpoints in cardiovascular ageing

European Heart Journal
2023-12-07 | Journal article
DOI: 10.1093/eurheartj/ehad661
Contributors: Mahmoud Abdellatif; Léa Montégut; Guido Kroemer
Source: check_circle
Crossref

Hallmarks of cardiovascular ageing

Nature Reviews Cardiology
2023-11 | Journal article
DOI: 10.1038/s41569-023-00881-3
Contributors: Mahmoud Abdellatif; Peter P. Rainer; Simon Sedej; Guido Kroemer
Source: check_circle
Crossref

Antagonistic pleiotropy: the example of cardiac insulin-like growth factor signaling, which is essential in youth but detrimental in age

Expert Opinion on Therapeutic Targets
2023-02-01 | Journal article
DOI: 10.1080/14728222.2023.2178420
Contributors: Mahmoud Abdellatif; Frank Madeo; Simon Sedej; Guido Kroemer
Source: check_circle
Crossref

High plasma concentrations of acyl‐coenzyme A binding protein (ACBP) predispose to cardiovascular disease: Evidence for a phylogenetically conserved proaging function of ACBP

Aging Cell
2023-01 | Journal article
DOI: 10.1111/acel.13751
Contributors: Léa Montégut; Adrien Joseph; Hui Chen; Mahmoud Abdellatif; Christoph Ruckenstuhl; Omar Motiño; Flavia Lambertucci; Gerasimos Anagnostopoulos; Sylvie Lachkar; Silvia Dichtinger et al.
Source: check_circle
Crossref

NAD+ and Vascular Dysfunction: From Mechanisms to Therapeutic Opportunities

Journal of Lipid and Atherosclerosis
2022 | Journal article
DOI: 10.12997/jla.2022.11.2.111
Contributors: Mahmoud Abdellatif; Heiko Bugger; Guido Kroemer; Simon Sedej
Source: check_circle
Crossref

Response by Sedej and Abdellatif to Letter Regarding Article, “Fine-Tuning Cardiac Insulin-Like Growth Factor 1 Receptor Signaling to Promote Health and Longevity”

Circulation
2022-12-13 | Journal article
DOI: 10.1161/CIRCULATIONAHA.122.062496
Contributors: Simon Sedej; Mahmoud Abdellatif
Source: check_circle
Crossref

Fine-Tuning Cardiac Insulin-Like Growth Factor 1 Receptor Signaling to Promote Health and Longevity

Circulation
2022-06-21 | Journal article
DOI: 10.1161/CIRCULATIONAHA.122.059863
Contributors: Mahmoud Abdellatif; Viktoria Trummer-Herbst; Alexander Martin Heberle; Alina Humnig; Tobias Pendl; Sylvère Durand; Giulia Cerrato; Sebastian J. Hofer; Moydul Islam; Julia Voglhuber et al.
Source: check_circle
Crossref

Loss of autophagy protein ATG5 impairs cardiac capacity in mice and humans through diminishing mitochondrial abundance and disrupting Ca2+ cycling

Cardiovascular Research
2022-05-06 | Journal article
DOI: 10.1093/cvr/cvab112
Contributors: Senka Ljubojević-Holzer; Simon Kraler; Nataša Djalinac; Mahmoud Abdellatif; Julia Voglhuber; Julia Schipke; Marlene Schmidt; Katharina-Maria Kling; Greta Therese Franke; Viktoria Herbst et al.
Source: check_circle
Crossref

NAD + Metabolism in Cardiac Health, Aging, and Disease

Circulation
2021-11-30 | Journal article
DOI: 10.1161/CIRCULATIONAHA.121.056589
Contributors: Mahmoud Abdellatif; Simon Sedej; Guido Kroemer
Source: check_circle
Crossref

NAD+ metabolism and cardiometabolic health: the human evidence

Cardiovascular Research
2021-07-27 | Journal article
DOI: 10.1093/cvr/cvab212
Contributors: Mahmoud Abdellatif; Joseph A Baur
Source: check_circle
Crossref

Scientists on the Spot: A fraction of wisdom on heart failure

Cardiovascular Research
2021-07-27 | Journal article
DOI: 10.1093/cvr/cvab230
Contributors: Mahmoud Abdellatif; Carolyn S P Lam
Source: check_circle
Crossref

Exercise-induced sudden cardiac death is caused by mitochondrio-nuclear translocation of AIF

Cell Death & Disease
2021-04-09 | Journal article
DOI: 10.1038/s41419-021-03677-w
Contributors: Mahmoud Abdellatif; Guido Kroemer
Source: check_circle
Crossref

Nicotinamide for the treatment of heart failure with preserved ejection fraction

Science Translational Medicine
2021-02-10 | Journal article
DOI: 10.1126/scitranslmed.abd7064
Contributors: Mahmoud Abdellatif; Viktoria Trummer-Herbst; Franziska Koser; Sylvère Durand; Rui Adão; Francisco Vasques-Nóvoa; Johanna K. Freundt; Julia Voglhuber; Maria-Rosaria Pricolo; Michael Kasa et al.
Source: check_circle
Crossref

Co-ordinated mitochondrial degradation by autophagy and heterophagy in cardiac homeostasis

Cardiovascular Research
2021-01-01 | Journal article
DOI: 10.1093/cvr/cvaa345
Contributors: Mahmoud Abdellatif; Guido Kroemer
Source: check_circle
Crossref

Scientists on the Spot: from the Scientists of Tomorrow to the scientist of today

Cardiovascular Research
2020-11-01 | Journal article
DOI: 10.1093/cvr/cvaa277
Contributors: Mahmoud Abdellatif; Gemma Vilahur
Source: check_circle
Crossref

Immunometabolism: a key target to improve microcirculation in ageing

Cardiovascular Research
2020-04-01 | Journal article
DOI: 10.1093/cvr/cvaa060
Contributors: Mahmoud Abdellatif; Andreas Zirlik
Source: check_circle
Crossref

Cardiovascular benefits of intermittent fasting

Cardiovascular Research
2020-03-01 | Journal article
DOI: 10.1093/cvr/cvaa022
Contributors: Mahmoud Abdellatif; Simon Sedej
Source: check_circle
Crossref

Revitalising the aged heart through spermidine-rich diet

HealthManagement
2019 | Magazine article
Source: Self-asserted source
Mahmoud Abdellatif

Highlights of ESC Congress 2019: a report from the ESC Scientists of Tomorrow

Cardiovascular Research
2019-11-01 | Journal article
DOI: 10.1093/cvr/cvz266
Contributors: Mahmoud Abdellatif; Jyoti Patel; Anke M Smits
Source: check_circle
Crossref

The flavonoid 4,4'-dimethoxychalcone promotes autophagy-dependent longevity across species.

Nature communications
2019-02 | Journal article
DOI: 10.1038/s41467-019-08555-w
PMID: 30783116
PMC: PMC6381180
Contributors: Carmona-Gutierrez D; Zimmermann A; Kainz K; Pietrocola F; Chen G; Maglioni S; Schiavi A; Nah J; Mertel S; Beuschel CB et al.
Source: Self-asserted source
Mahmoud Abdellatif via Europe PubMed Central

Cardioprotection by spermidine does not depend on structural characteristics of the myocardial microcirculation in aged mice.

Experimental gerontology
2019-01 | Journal article
DOI: 10.1016/j.exger.2019.01.026
PMID: 30703435
Contributors: Wierich MC; Schipke J; Brandenberger C; Abdellatif M; Eisenberg T; Madeo F; Sedej S; Mühlfeld C
Source: Self-asserted source
Mahmoud Abdellatif via Europe PubMed Central

Should we skip a meal every day?

JATROS Kardiologie & Gefäßmedizin
2018 | Magazine article
Source: Self-asserted source
Mahmoud Abdellatif

Cardioprotective effects of autophagy induction in sepsis.

Annals of translational medicine
2018-11 | Journal article
DOI: 10.21037/atm.2018.10.23
PMID: 30613636
PMC: PMC6291539
Contributors: Abdellatif M; Sedej S; Madeo F; Kroemer G
Source: Self-asserted source
Mahmoud Abdellatif via Europe PubMed Central

Autophagy in Cardiovascular Aging.

Circulation research
2018-09 | Journal article
DOI: 10.1161/circresaha.118.312208
PMID: 30355077
Contributors: Abdellatif M; Sedej S; Carmona-Gutierrez D; Madeo F; Kroemer G
Source: Self-asserted source
Mahmoud Abdellatif via Europe PubMed Central

Cold-Induced Thermogenesis Depends on ATGL-Mediated Lipolysis in Cardiac Muscle, but Not Brown Adipose Tissue.

Cell metabolism
2017-10 | Journal article
DOI: 10.1016/j.cmet.2017.09.004
PMID: 28988821
PMC: PMC5683855
Contributors: Schreiber R; Diwoky C; Schoiswohl G; Feiler U; Wongsiriroj N; Abdellatif M; Kolb D; Hoeks J; Kershaw EE; Sedej S et al.
Source: Self-asserted source
Mahmoud Abdellatif via Europe PubMed Central

Dietary spermidine for lowering high blood pressure.

Autophagy
2017-01 | Journal article
DOI: 10.1080/15548627.2017.1280225
PMID: 28118075
PMC: PMC5381711
Contributors: Eisenberg T; Abdellatif M; Zimmermann A; Schroeder S; Pendl T; Harger A; Stekovic S; Schipke J; Magnes C; Schmidt A et al.
Source: Self-asserted source
Mahmoud Abdellatif via Europe PubMed Central

Cardioprotection and lifespan extension by the natural polyamine spermidine.

Nature medicine
2016-11 | Journal article
DOI: 10.1038/nm.4222
PMID: 27841876
PMC: PMC5806691
Contributors: Eisenberg T; Abdellatif M; Schroeder S; Primessnig U; Stekovic S; Pendl T; Harger A; Schipke J; Zimmermann A; Schmidt A et al.
Source: Self-asserted source
Mahmoud Abdellatif via Europe PubMed Central

Right ventricular end-diastolic stiffness heralds right ventricular failure in monocrotaline-induced pulmonary hypertension.

American journal of physiology. Heart and circulatory physiology
2016-07 | Journal article
DOI: 10.1152/ajpheart.00202.2016
PMID: 27473939
Contributors: Alaa M; Abdellatif M; Tavares-Silva M; Oliveira-Pinto J; Lopes L; Leite S; Leite-Moreira AF; Lourenço AP
Source: Self-asserted source
Mahmoud Abdellatif via Europe PubMed Central

Spectral transfer function analysis of respiratory hemodynamic fluctuations predicts end-diastolic stiffness in preserved ejection fraction heart failure.

American journal of physiology. Heart and circulatory physiology
2015-10 | Journal article
DOI: 10.1152/ajpheart.00399.2015
PMID: 26475584
Contributors: Abdellatif M; Leite S; Alaa M; Oliveira-Pinto J; Tavares-Silva M; Fontoura D; Falcão-Pires I; Leite-Moreira AF; Lourenço AP
Source: Self-asserted source
Mahmoud Abdellatif via Europe PubMed Central

Afterload-induced diastolic dysfunction contributes to high filling pressures in experimental heart failure with preserved ejection fraction.

American journal of physiology. Heart and circulatory physiology
2015-09 | Journal article
DOI: 10.1152/ajpheart.00397.2015
PMID: 26408538
Contributors: Leite S; Rodrigues S; Tavares-Silva M; Oliveira-Pinto J; Alaa M; Abdellatif M; Fontoura D; Falcão-Pires I; Gillebert TC; Leite-Moreira AF et al.
Source: Self-asserted source
Mahmoud Abdellatif via Europe PubMed Central

Impairment of preload reserve in experimental heart failure with preserved ejection fraction: can spectral analysis contribute to diagnosis?

2nd World Congress - Acute Heart Failure 2015, Seville, Spain.
2015-05-25 | Conference poster
Source: Self-asserted source
Mahmoud Abdellatif

Echocardiography and invasive hemodynamics during stress testing for diagnosis of heart failure with preserved ejection fraction: an experimental study.

2015-04 | Journal article
DOI:

10.1152/ajpheart.00076.2015

PMID:

25862827
Contributors: Leite S; Pinto JO; Silva MT; Abdellatif M; Fontoura D; Falcão-Pires I; Leite-Moreira AF; Lourenço AP
Source: Self-asserted source
Mahmoud Abdellatif via Europe PubMed Central

Peer review (16 reviews for 8 publications/grants)

Review activity for Drugs & aging (1)
Review activity for European heart journal. (8)
Review activity for Journal of translational medicine. (1)
Review activity for Nature cardiovascular research. (1)
Review activity for Nature communications (1)
Review activity for PLoS biology. (1)
Review activity for Signal transduction and targeted therapy. (1)
Review activity for The Lancet Healthy Longevity (2)
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