Personal information

Emails & domains

Verified email addresses

Verified email domains

Websites & social links

Sarka Lehtonen web page
Research gate
Lehtonen lab
Lehtonen lab sites

Other IDs

Scopus Author ID: 23091344600
Loop profile: 422452

Keywords

Parkinson`s disease, Blood-brain barrier, Stem Cells, Schizophrenia, Psychopathy, Organ-on-Chip

Countries

Finland, Czech Republic

Biography

PERSONAL DETAILS
Surname: Lehtonen (née Maňáková)
First name: Šárka
Website: https://sites.uef.fi/human-brain-disease-modelling-group/sarka-lehtonen/
DEGREES
Doctor of Pharmacy in Pharmacology, Department of Pharmacology and Toxicology, University of Kuopio, Finland. Thesis title: “Studies on the mechanisms of 6-OHDA in non-neuronal and neuronal cells” Graduation date: 15.4.2005
Master of Science, Faculty of Pharmacy in Hradec Kralove, Charles University, Prague, Czech Republic. M.Sc. thesis: Dopaminergic and α2-adrenergic regulation of tyrosine hydroxylase in the rat model of Parkinsonʾs disease. Graduation date: 3.6.1999
Title of Docent in Neuropharmacology, University of Eastern Finland, date: 1.12.2016
OTHER EDUCATION AND EXPERTISE
Pedagogic skills:
Working as a lecturer and counsellor at the University of Eastern Finland, 2021 (1 ECTS). Planning of Learning Processes for Web-based and Contact Teaching, 2020 (4 ECTS). Pedagogical communication, 2016 (2 ECTS). Pedagogics in University Education, 2008 (3 ECTS). Basics of Moodle, 2007 (1 ECTS).
LANGUAGE SKILLS
Czech (native), English (excellent – spoken and written), Finnish (fluent – spoken, good – written)
CURRENT EMPLOYMENT
Research Director, University of Eastern Finland (UEF), A.I.Virtanen Institute for Molecular Sciences, Finland. From 1.5.2024 – ; Research career phase: Established researcher, Project investigator, Head of Human Brain Disease Modelling group from 1.2.2021

Activities

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Employment (9)

University of Eastern Finland: Kuopio, FI

2024-05-01 to present | Research Director (A.I.Virtanen Institute)
Employment
Source: Self-asserted source
Manakova or Lehtonen

Neuroscience Center, University of Helsinki: Helsinki, FI

2018-03-01 to present | Visiting Researcher
Employment
Source: Self-asserted source
Manakova or Lehtonen

University of Eastern Finland: Kuopio, FI

2021-04-01 to 2024-04-30 | Sigrid Juselius Senior Research Fellow (A.I.Virtanen Institute for Molecular Sciences)
Employment
Source: Self-asserted source
Manakova or Lehtonen

University of Eastern Finland: Kuopio, FI

2017-07-01 to 2021-03-31 | University researcher
Employment
Source: Self-asserted source
Manakova or Lehtonen

University of Eastern Finland: Kuopio, FI

2014-01-01 to 2017-06-30 | Saastamoinen fellowship
Employment
Source: Self-asserted source
Manakova or Lehtonen

Masaryk University: Brno, CZ

2012-08-01 to 2013-03-31 | Visiting researcher, Laboratory of Prof. Petr Dvorák
Employment
Source: Self-asserted source
Manakova or Lehtonen

A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland: Kuopio, FI

2010-06-01 to 2012-06-30 | Research co-ordinator of European Social Fund
Employment
Source: Self-asserted source
Manakova or Lehtonen

University of Eastern Finland: Kuopio, FI

2007-02-01 to 2011-12-01 | Assistant in Pharmacology (Department of Pharmacology and Toxicology)
Employment
Source: Self-asserted source
Manakova or Lehtonen

University of Helsinki: Helsinki, FI

2005-05-01 to 2007-01-31 | Postdoctoral Researcher (Department of Pharmacology, Medical Faculty)
Employment
Source: Self-asserted source
Manakova or Lehtonen

Education and qualifications (3)

University of Eastern Finland: Kuopio, FI

2016-12-01 to present | Docent in Neuropharmacology
Qualification
Source: Self-asserted source
Manakova or Lehtonen

University of Eastern Finland: Kuopio, FI

2005-04-15 to present | PhD in Pharmacology
Education
Source: Self-asserted source
Manakova or Lehtonen

Charles University: Prague, CZ

1999 to present | M.Sci in pharmacy (Faculty of Pharmacy)
Education
Source: Self-asserted source
Manakova or Lehtonen

Professional activities (5)

Brain research society of Finland: Helsinki, FI

2020-05-13 to present
Membership
Source: Self-asserted source
Manakova or Lehtonen

The Finnish Society for Developmental Biology: Helsinki, FI

2015 to present | Member
Membership
Source: Self-asserted source
Manakova or Lehtonen

International Society for Stem Cell Research: Skokie, IL, US

2014 to present | Member
Membership
Source: Self-asserted source
Manakova or Lehtonen

The Finnish Pharmacological Society: Helsinki, FI

2004 to present | Member
Membership
Source: Self-asserted source
Manakova or Lehtonen

University of Eastern Finland: Kuopio, FI

2016 | Docent in Neuropharmacology
Distinction
Source: Self-asserted source
Manakova or Lehtonen

Funding (9)

Brain-on-a-chip

2022-04 to 2022-11 | Grant
University of Eastern Finland-Proof of concept (Kuopio, FI)
Source: Self-asserted source
Manakova or Lehtonen

Metabolic profiling of human microglia from LRRK2 Parkinson's disease patients

2022-01 to 2022-12 | Grant
Päivikki and Sakari Sohlberg Foundation (Helsinki, FI)
Source: Self-asserted source
Manakova or Lehtonen

Microglia-driven pathology in PD

2021-04 to 2024-03 | Grant
Sigrid Juséliuksen Säätiö -varttunut tutkija (Helsinki, FI)
Source: Self-asserted source
Manakova or Lehtonen

Molecular crosstalk between astrocytes and microglia in Parkinson`s disease

2021-01 to 2023-12 | Grant
Jane ja Aatos Erkon Säätiö - start up grant (Helsinki, FI)
Source: Self-asserted source
Manakova or Lehtonen

Towards novel therapeutic strategies in schizophrenia

2021-01 to 2021-12 | Grant
Jalmari ja Rauha Ahokkaan Säätiö (Helsinki, FI)
Source: Self-asserted source
Manakova or Lehtonen

The Role of Glial Cells in Parkinson`s disease

2020-05 to 2023-04 | Grant
Sigrid Juséliuksen Säätiö- young group leader (Helsinki, FI)
Source: Self-asserted source
Manakova or Lehtonen

Extracellular Vesicle Ecosystem for the Development of Theranostic Platforms

2020-01 to 2022-12 | Grant
Business Finland-consortium project-partner (Helsinki, FI)
Source: Self-asserted source
Manakova or Lehtonen

Patient-derived blood-brain barrier platform

2019-04 to 2019-12 | Award
University of Eastern Finland-Proof of Concept - PI (Kuopio, Eastern Finland, Finland, Kuopio, FI)
Source: Self-asserted source
Manakova or Lehtonen

Schizophrenia-human-based models

2014-01 to 2017-06 | Grant
Saastamoinen säätiö - fellowship (Kuopio, Eastern Finland, Finland, FI)
Source: Self-asserted source
Manakova or Lehtonen
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