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myocardial infarction, cardiology
United States

Biography

I am a translational researcher leveraging my expertise in cohort development, clinical trials, clinical cardiology, cardiovascular epidemiology, bio-banking, and biomarker development to better understand atherosclerotic cardiovascular disease (ASCVD) and to improve ASCVD risk prediction. I completed a Masters of Science in Clinical Research graduate program at Emory University, am a board-certified Cardiologist and Associate Professor of Medicine in the Division of Cardiovascular Medicine at Vanderbilt University Medical Center, and an Adjunct Assistant Professor of Medicine at Johns Hopkins University and the University of Louisville. I am the Medical Director of the Cardiovascular Intensive Care Unit at Vanderbilt University and the Associate Program Director for the Internal Medicine Residency Program—Research Focus. I have significant experience with the Multi-Ethnic Study of Atherosclerosis (MESA); serve on the MESA Project & Publication Committee and am the co-PI of a R-01 that is utilizing MESA to define the epidemiology of the etiologically defined subtypes of myocardial injury and infarction (1R01HL158976-01). I serve on the Steering Committee for the Myocardial Ischemia and Transfusion (MINT) Trial. MINT is a National Institutes of Health (NIH) funded randomized control trial with over 100 sites around the world. My work has been published in multiple peer-reviewed journals, including the New England Journal of Medicine, Annals of Internal Medicine, The Lancet, Journal of the American College of Cardiology, European Heart Journal, and Circulation. My ongoing clinical work allows me to identify the questions that can make the largest and most immediate contributions to science and society. My experience as a PI on NIH, Foundation, and Industry Grants has taught me the importance of collaboration, leadership, communication, and planning needed to successfully orchestrate innovative projects.

My career has been and continues to be influenced by multiple scientific and career mentors. More importantly, my work has been shaped by many bright trainees who I have had the pleasure of working with. I strive to provide a structured environment for trainees that provides specific training in experimental design, methodology, analysis, interpretation, and reporting of results while providing the mentee room to think creatively and find their specific scientific passion. My laboratory seeks diversity, including diversity of demographic and training backgrounds as well as a diversity of scientific ideas and approaches. In addition to scientific knowledge and methodology, mentees in my laboratory receive training in project management, productivity, and exposure to different scientific careers. I leverage the resources at my institution, Vanderbilt University, and throughout my research network, including MESA and MINT, to afford trainees a greater diversity of ideas and resources.

Activities

Employment (16)

Vanderbilt University Medical Center: Nashville, US

2023-07 to present | Associate Director (Department of Medicine, Internal Medicine Residency Program)
Employment
Source: Self-asserted source
Andrew DeFilippis

University of Louisville: Louisville, Kentucky, US

2020-10 to present | Adjunct Assistant Professor of Medicine (Department of Medicine)
Employment
Source: Self-asserted source
Andrew DeFilippis

Vanderbilt University Medical Center: Nashville, US

2020-09 to present | Medical Director (Department of Medicine, Division of Cardiovascular Medicine)
Employment
Source: Self-asserted source
Andrew DeFilippis

Vanderbilt University Medical Center: Nashville, US

2020-09 to present | Associate Professor of Medicine (Department of Medicine)
Employment
Source: Self-asserted source
Andrew DeFilippis

Vanderbilt University Medical Center: Nashville, US

2020-09 to present | Rotation Director (Department of Medicine, Division of Cardiovascular Medicine)
Employment
Source: Self-asserted source
Andrew DeFilippis

Johns Hopkins University: Baltimore, US

2012-01 to present | Assistant Professor of Medicine (Department of Medicine)
Employment
Source: Self-asserted source
Andrew DeFilippis

University of Louisville: Louisville, Kentucky, US

2020-04 to 2020-09 | Interim Chief of Cardiovascular Medicine (Department of Medicine)
Employment
Source: Self-asserted source
Andrew DeFilippis

Louisville VA Medical Center: Louisville, Kentucky, US

2018 to 2020-09 | Attending Physician
Employment
Source: Self-asserted source
Andrew DeFilippis

University of Louisville: Louisville, Kentucky, US

2017-04 to 2020-09 | Associate Professor of Medicine with Tenure (Department of Medicine, Division of Cardiovascular Medicine)
Employment
Source: Self-asserted source
Andrew DeFilippis

University of Louisville: Louisville, Kentucky, US

2011-10 to 2020 | Director (Cardiovascular Disease Prevention Program)
Employment
Source: Self-asserted source
Andrew DeFilippis

University of Louisville: Louisville, Kentucky, US

2011-10 to 2020 | Assistant Professor of Physiology (Department of Physiology)
Employment
Source: Self-asserted source
Andrew DeFilippis

University of Louisville: Louisville, Kentucky, US

2012-12 to 2018-06 | Member, Biomedical Institutional Review Board
Employment
Source: Self-asserted source
Andrew DeFilippis

University of Louisville: Louisville, Kentucky, US

2012-12 to 2018-06 | Co-Director (Ambulatory Internal Medicine (AIM) Clinic)
Employment
Source: Self-asserted source
Andrew DeFilippis

University of Louisville: Louisville, Kentucky, US

2011-10 to 2017-04 | Director, Cardiovascular Intensive Care (Department of Medicine)
Employment
Source: Self-asserted source
Andrew DeFilippis

Emory University: Atlanta, US

2006-06 to 2007-05 | Assistant Professor of Medicine (Department of Medicine)
Employment
Source: Self-asserted source
Andrew DeFilippis

Emory University: Atlanta, US

2004-06 to 2006-05 | Instructor of Medicine (Department of Medicine)
Employment
Source: Self-asserted source
Andrew DeFilippis

Education and qualifications (7)

Johns Hopkins University: Baltimore, US

2010-06 to 2011-09 | Post-Doctoral Fellowship, Proteomics - Jennifer VanEyk Lab
Education
Source: Self-asserted source
Andrew DeFilippis

Johns Hopkins University: Baltimore, US

2007-06 to 2011-05 | Cardiovascular Medicine Fellowship
Education
Source: Self-asserted source
Andrew DeFilippis

Emory University: Atlanta, US

2004-08 to 2006-05 | Masters of Science in Clinical Research
Education
Source: Self-asserted source
Andrew DeFilippis

Emory University: Atlanta, US

2001-06 to 2004-05 | Internal Medicine Residency
Education
Source: Self-asserted source
Andrew DeFilippis

Georgetown University: Washington, US

1997-09 to 2001-05 | Doctorate of Medicine
Education
Source: Self-asserted source
Andrew DeFilippis

National Cancer Institute: Bethesda, US

1995-06 to 1997-05 | Pre-Doctoral Intramural Research Training Award Program (National Institutes of Health)
Education
Source: Self-asserted source
Andrew DeFilippis

James Madison University: Harrisonburg, US

1991-08 to 1995-05 | Bachelor of Science, Biology
Education
Source: Self-asserted source
Andrew DeFilippis

Professional activities (25)

Vanderbilt University Medical Center: Nashville, US

2021 to present | American College of Cardiology Cardiac Arrest Resuscitation adn Therapeutic Temperature Management Accreditation Committee
Membership
Source: Self-asserted source
Andrew DeFilippis

Vanderbilt University Medical Center: Nashville, US

2021 to present (American College of Cardiology Chest Pain Accreditation Committee)
Membership
Source: Self-asserted source
Andrew DeFilippis

Vanderbilt University Medical Center: Nashville, US

2021 to present (High Sensitivity Troponin Assay Implementation)
Membership
Source: Self-asserted source
Andrew DeFilippis

Vanderbilt University Medical Center: Nashville, US

2021 to present (Mortality Review Committee)
Membership
Source: Self-asserted source
Andrew DeFilippis

Vanderbilt University Medical Center: Nashville, US

2020 to present (ST Elevation Myocardial Infarction Committee)
Membership
Source: Self-asserted source
Andrew DeFilippis

Vanderbilt University Medical Center: Nashville, US

2020 to present (Quality Leadership Committee)
Membership
Source: Self-asserted source
Andrew DeFilippis

American College of Cardiology: Washington D.C., District of Columbia, US

2020 to present | Critical Care Cardiology
Membership
Source: Self-asserted source
Andrew DeFilippis

Myocardial Ischemia and Transfusion (MINT) Study: Piscataway, New Jersey, US

2018 to present | Steering Committee Member
Membership
Source: Self-asserted source
Andrew DeFilippis

Multi-Ethnic Study of Atherosclerosis (MESA): Seattle, Washington, US

2017 to present (Project and Publication Committee)
Membership
Source: Self-asserted source
Andrew DeFilippis

Critical Care Cardiology Trials Network (CCCTN): Cambridge, Massachusetts, US

2017 to present (Multicenter Registry of Cardiac Critical Illness)
Membership
Source: Self-asserted source
Andrew DeFilippis

American College of Cardiology: Washington D.C., District of Columbia, US

2007 to present
Membership
Source: Self-asserted source
Andrew DeFilippis

American Heart Association: Dallas, US

2005 to present (Arteriosclerosis, Thrombosis, and Vascular Biology)
Membership
Source: Self-asserted source
Andrew DeFilippis

American Heart Association: Dallas, US

2005 to present (Epidemiology and Prevention)
Membership
Source: Self-asserted source
Andrew DeFilippis

Kentucky Chapter of the American College of Cardiology (KY-ACC): Louisville, Kentucky, US

2018 to 2020 | Board of Directors and Chapter Council
Membership
Source: Self-asserted source
Andrew DeFilippis

American Heart Association: Dallas, US

2018 to 2019 | President (Kentuckiana Board of Directors)
Membership
Source: Self-asserted source
Andrew DeFilippis

American Heart Association: Dallas, US

2017 to 2017 | President-Elect (Kentuckiana Board of Directors)
Membership
Source: Self-asserted source
Andrew DeFilippis

KentuckyOne Health: Louisville, Kentucky, US

2016 to 2016 (Cardiovascular Service Line Committee)
Membership
Source: Self-asserted source
Andrew DeFilippis

Jewish Hospital: Louisville, Kentucky, US

2016 to 2016 (Council of Chiefs)
Membership
Source: Self-asserted source
Andrew DeFilippis

University of Louisville: Louisville, Kentucky, US

2013 to 2016 (Cardiac Resuscitation Center Committee)
Membership
Source: Self-asserted source
Andrew DeFilippis

University of Louisville: Louisville, Kentucky, US

2013 to 2016 (STEMI Network Committee)
Membership
Source: Self-asserted source
Andrew DeFilippis

University of Louisville: Louisville, Kentucky, US

2013 to 2016 (Critical Care Task Force)
Membership
Source: Self-asserted source
Andrew DeFilippis

University of Louisville: Louisville, Kentucky, US

2013 to 2016 (Intensive Care Committee)
Membership
Source: Self-asserted source
Andrew DeFilippis

University of Louisville: Louisville, Kentucky, US

2013 to 2015 (Member, Biomedical Institutional Review Board)
Membership
Source: Self-asserted source
Andrew DeFilippis

Agency for Healthcare Research and Quality: Rockville, Maryland, US

2013 to 2013 | Technical Expert (Project Title: "Troponin Cardiac Marker Interpretation During Renal Function Impairment")
Membership
Source: Self-asserted source
Andrew DeFilippis

National Lipid Association (NLA): Jacksonville, Florida, US

2005 to 2011
Membership
Source: Self-asserted source
Andrew DeFilippis

Funding (27)

Extreme Temperature Events and Myocardial Infarction

2024-04 to 2027-03 | Grant
American Heart Association (TX, TX, US)
GRANT_NUMBER: 24SCEFIA1262221
Source: Self-asserted source
Andrew DeFilippis

Contemporary Classification of Myocardial Injury Events in MESA: Defining Distinct Risk Factor Associations with Myocardial Infarction Type 1-5 and Acute Non-Ischemic Myocardial Injury

2021-08-20 to 2026-07-31 | Grant
National Heart Lung and Blood Institute (Bethesda, US)
GRANT_NUMBER: R01HL158976
Source: Self-asserted source
Andrew DeFilippis via DimensionsWizard

Integrated Proteomic and Metabolomics Analysis of Thrombotic Myocardial Infarction

2021-02 to 2025-01 | Award
National Institutes of Health (Md., Md., US)
GRANT_NUMBER: 1SC1GM139730
Source: Self-asserted source
Andrew DeFilippis

Impact of Greenspaces on Cardiovascular Health Assessed at the Population Level

2020-03 to 2021-02 | Grant
Jewish Heritage Fund for Excellence (Louisville, Kentucky, US)
Source: Self-asserted source
Andrew DeFilippis

Angiotensinogen and ASCVD in MESA

2019-12 to 2023-11 | Grant
Ionis Pharmaceuticals (CA, CA, US)
Source: Self-asserted source
Andrew DeFilippis

Continuation-Development of Differential Scanning Calorimetry System for Rapid Identification & Differentiation of Specific Causes of Heart Damage

2019-09 to 2023-08 | Grant
National Heart, Lung, and Blood Institute (Md., Md., US)
GRANT_NUMBER: 5U01HL152392-02
Source: Self-asserted source
Andrew DeFilippis

Understanding the Role of Anti-Apolipoprotein A-I Antibodies in Atherosclerotic Cardiovascular Disease

2019-09 to 2020-08 | Grant
National Institutes of Health (Md., Md., US)
GRANT_NUMBER:

R01 HL152081

Source: Self-asserted source
Andrew DeFilippis

Point-of-Care Differential Scanning Calorimeter for diagnosis of Myocardial Infarction and Myocardial Infarction Sub-types

2019-08 to 2020-02 | Grant
University of Louisville (Louisville, Kentucky, US)
GRANT_NUMBER:

U01HL127518

Source: Self-asserted source
Andrew DeFilippis

Identification and Classification of Acute Myocardial Infarction

2019-05 to 2020-04 | Grant
Jewish Heritage Fund for Excellence (Louisville, Kentucky, US)
Source: Self-asserted source
Andrew DeFilippis

Cardiovascular Research Fund

2019 to 2019 | Grant
Mary K Oxley Foundation (Louisville, Kentucky, US)
Source: Self-asserted source
Andrew DeFilippis

AHA Tobacco Regulation and Addiction Center

2018-09 to 2023-06 | Grant
National Institutes of Health (Md., Md., US)
GRANT_NUMBER:

2U54HL120163

Source: Self-asserted source
Andrew DeFilippis

Urban Greenness and Cardiovascular Health

2018-07 to 2023-06 | Grant
National Institutes of Health (Md., Md., US)
GRANT_NUMBER:

1R01ES029846-01

Source: Self-asserted source
Andrew DeFilippis

Endothelial Progenitor Cells and Particular Air Pollution

2018-04 to 2023-03 | Grant
National Institutes of Health (Md., Md., US)
GRANT_NUMBER:

2R01 ES019217-06

Source: Self-asserted source
Andrew DeFilippis

Biomarker Development for the Identification and Dfiferentiation of Myocardial Infarction Subtypes

2018 to 2021 | Grant
James Ryan Fund for Cardiovascular Biomarker Research (Louisville, Kentucky, US)
Source: Self-asserted source
Andrew DeFilippis

MiHEART-ECIG

2017-07 to 2018-08 | Grant
American Heart Association (TX, TX, US)
GRANT_NUMBER:

2003783180

Source: Self-asserted source
Andrew DeFilippis

The Role of Oxidized Phospholipids Bound to Plasminogen in Atherothrombotic Myocardial Infarction

2016-07 to 2019-08 | Grant
Alpha Phi Foundation (Louisville, Kentucky, US)
GRANT_NUMBER:

Heart to Heart Grant

Source: Self-asserted source
Andrew DeFilippis

Cardiovascular Toxicity of Tobacco Products and Constituents

2015-07 to 2020-04 | Grant
National Institutes of Health (Bethesda, US)
Source: Self-asserted source
Andrew DeFilippis

Exposure to Environmental Aldehydes and Cardiovascular Disease Risk

2014-09 to 2018-06 | Grant
WellPoint (IN, IN, US)
Source: Self-asserted source
Andrew DeFilippis

Identifying Patients at High Risk for Heart Failure Readmission

2014-09 to 2018-06 | Grant
Roche Diagnostics (IN, IN, US)
Source: Self-asserted source
Andrew DeFilippis

AHA Tobacco Regulation, Addiction and Regulation (A-TRAC)

2013-09 to present | Grant
National Institutes of Health (Bethesda, US)
Source: Self-asserted source
Andrew DeFilippis

The Impact of Ticagrelor on In-Vivo Measures of Platelet Activation in Diabetics During Acute Atherothrombotic MI

2013-06 to 2020-04 | Grant
AstraZeneca (Cambridge, GB)
Source: Self-asserted source
Andrew DeFilippis

Immunosuppressive Diagnostics

2013-04 to 2014-12 | Grant
Roche Diagnostics (IN, IN, US)
GRANT_NUMBER:

OICN130966

Source: Self-asserted source
Andrew DeFilippis

Early Diagnosis of Atherothrombotic Acute Coronary Syndromes

2011-07-01 to 2013-06-30 | Grant
American Heart Association (Dallas, US)
GRANT_NUMBER:

11CRP7300003

Source: Self-asserted source
Andrew DeFilippis via DimensionsWizard

Platelet Activation and Coronary Thrombosis

2010-06 to 2015-07 | Award
Johns Hopkins Cole Family Clinical Research Award (Baltimore, Maryland, US)
Source: Self-asserted source
Andrew DeFilippis

Platelet Activation and Coronary Thrombosis

2009-06 to 2011-07 | Award
Johns Hopkins Ciccarone Center Research Award (Baltimore, Maryland, US)
Source: Self-asserted source
Andrew DeFilippis

Aspirin-Insensitive Thromboxane Generation and Coronary Thrombosis

2009-03 to 2011-04 | Grant
Johns Hopkins University (Baltimore, US)
Source: Self-asserted source
Andrew DeFilippis

Center for Excellence in Diabetes and Obesity Research

2008-09-26 to 2018-06-30 | Grant
National Institute of General Medical Sciences (Bethesda, US)
GRANT_NUMBER: P20GM103492
Source: Self-asserted source
Andrew DeFilippis via DimensionsWizard

Peer review (9 reviews for 3 publications/grants)

Review activity for JACC. (1)
Review activity for Journal of the American College of Cardiology (7)
Review activity for npj digital medicine. (1)