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Employment (1)

Cytiva: Uppsala, Uppsala, SE

2011-09-01 to present | Strategic Technology Leader (Strategic Technologies)
Employment
Source: Self-asserted source
Andreas Castan

Works (26)

Monitoring of amino acids and antibody N-glycosylation in high cell density perfusion culture based on Raman spectroscopy

Biochemical Engineering Journal
2022 | Journal article
EID:

2-s2.0-85127796396

Part of ISSN: 1873295X 1369703X
Contributors: Schwarz, H.; Mäkinen, M.E.; Castan, A.; Chotteau, V.
Source: Self-asserted source
Andreas Castan via Scopus - Elsevier

Integrated continuous biomanufacturing on pilot scale for acid‐sensitive monoclonal antibodies

Biotechnology and Bioengineering
2022-08 | Journal article
Contributors: Hubert Schwarz; Joaquín Gomis‐Fons; Madelène Isaksson; Julia Scheffel; Niklas Andersson; Andreas Andersson; Andreas Castan; Anita Solbrand; Sophia Hober; Bernt Nilsson et al.
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Shake tube perfusion cell cultures are suitable tools for the prediction of limiting substrate, CSPR, bleeding strategy, growth and productivity behavior

Journal of Chemical Technology and Biotechnology
2021 | Journal article
EID:

2-s2.0-85111390182

Part of ISSN: 10974660 02682575
Contributors: Mayrhofer, P.; Castan, A.; Kunert, R.
Source: Self-asserted source
Andreas Castan via Scopus - Elsevier

Probabilistic model by Bayesian network for the prediction of antibody glycosylation in perfusion and fed‐batch cell cultures

Biotechnology and Bioengineering
2021-09 | Journal article
Contributors: Liang Zhang; MingLiang Wang; Andreas Castan; Håkan Hjalmarsson; Veronique Chotteau
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Control of IgG glycosylation in CHO cell perfusion cultures by GReBA mathematical model supported by a novel targeted feed, TAFE

Metabolic Engineering
2021-05 | Journal article
Contributors: Liang Zhang; Hubert Schwarz; Mingliang Wang; Andreas Castan; Håkan Hjalmarsson; Veronique Chotteau
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Monitoring of heat- and light exposure of cell culture media by RAMAN spectroscopy: Towards an analytical tool for cell culture media quality control

Biochemical Engineering Journal
2021-02 | Journal article
Contributors: Patrick Mayrhofer; David Reinhart; Andreas Castan; Renate Kunert
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Glycan Residues Balance Analysis - GReBA: A novel model for the N-linked glycosylation of IgG produced by CHO cells

Metabolic Engineering
2020 | Journal article
EID:

2-s2.0-85074776776

Part of ISSN: 10967184 10967176
Contributors: Zhang, L.; Wang, M.; Castan, A.; Stevenson, J.; Chatzissavidou, N.; Hjalmarsson, H.; Vilaplana, F.; Chotteau, V.
Source: Self-asserted source
Andreas Castan via Scopus - Elsevier

Hydrocyclones as cell retention device for CHO perfusion processes in single‐use bioreactors

Biotechnology and Bioengineering
2020-07 | Journal article
Contributors: Ioná W. Bettinardi; Andreas Castan; Ricardo A. Medronho; Leda R. Castilho
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Model‐based design and control of a small‐scale integrated continuous end‐to‐end mAb platform

Biotechnology Progress
2020-07 | Journal article
Contributors: Joaquín Gomis‐Fons; Hubert Schwarz; Liang Zhang; Niklas Andersson; Bernt Nilsson; Andreas Castan; Anita Solbrand; Joanne Stevenson; Véronique Chotteau
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Rapid development of clone‐specific, high‐performing perfusion media from established feed supplements

Biotechnology Progress
2020-03 | Journal article
Contributors: Patrick Mayrhofer; David Reinhart; Andreas Castan; Renate Kunert
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Bioprocessing of Recombinant CHO-K1, CHO-DG44, and CHO-S: CHO Expression Hosts Favor Either mAb Production or Biomass Synthesis

Biotechnology Journal
2019 | Journal article
EID:

2-s2.0-85054440908

Part of ISSN: 18607314 18606768
Contributors: Reinhart, D.; Damjanovic, L.; Kaisermayer, C.; Sommeregger, W.; Gili, A.; Gasselhuber, B.; Castan, A.; Mayrhofer, P.; Grünwald-Gruber, C.; Kunert, R.
Source: Self-asserted source
Andreas Castan via Scopus - Elsevier

Combined effects of glycosylation precursors and lactate on the glycoprofile of IgG produced by CHO cells

Journal of Biotechnology
2019 | Journal article
EID:

2-s2.0-85057157868

Part of ISSN: 18734863 01681656
Contributors: Zhang, L.; Castan, A.; Stevenson, J.; Chatzissavidou, N.; Vilaplana, F.; Chotteau, V.
Source: Self-asserted source
Andreas Castan via Scopus - Elsevier

Single-use bioreactor platform for microbial fermentation

Single-Use Technology in Biopharmaceutical Manufacture
2019 | Book chapter
EID:

2-s2.0-85140934185

Contributors: Galliher, P.M.; Guertin, P.; Clapp, K.; Tuohey, C.; Damren, R.; Kehail, Y.; Colombie, V.; Castan, A.
Source: Self-asserted source
Andreas Castan via Scopus - Elsevier

Repurposing fed‐batch media and feeds for highly productive CHO perfusion processes

Biotechnology Progress
2019-07 | Journal article
Contributors: Marcel Kuiper; Chris Spencer; Eric Fäldt; Audrey Vuillemez; William Holmes; Teres Samuelsson; David Gruber; Andreas Castan
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Label-free independent quantitation of viable and non-viable cells using a multivariable multi-resonant sensor

Bioelectrochemistry
2019-02 | Journal article
Contributors: Radislav A. Potyrailo; Jon Dieringer; Victoria Cotero; Yongjae Lee; Steve Go; Matthew Schulmerich; Gunnar Malmquist; Andreas Castan; Klaus Gebauer; Vincent Pizzi
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Cell Line Development

Biopharmaceutical Processing: Development, Design, and Implementation of Manufacturing Processes
2018 | Book chapter
EID:

2-s2.0-85054368462

Contributors: Castan, A.; Schulz, P.; Wenger, T.; Fischer, S.
Source: Self-asserted source
Andreas Castan via Scopus - Elsevier

Differential gene expression of a feed-spiked super-producing CHO cell line

Journal of Biotechnology
2018 | Journal article
EID:

2-s2.0-85052745378

Part of ISSN: 18734863 01681656
Contributors: Reinhart, D.; Damjanovic, L.; Castan, A.; Ernst, W.; Kunert, R.
Source: Self-asserted source
Andreas Castan via Scopus - Elsevier

Next-Generation Bioprocess Techniques

Genetic Engineering and Biotechnology News
2018 | Journal article
EID:

2-s2.0-85052601388

Part of ISSN: 19378661 1935472X
Contributors: Castan, A.; Öhrvik, H.; Nelson, D.
Source: Self-asserted source
Andreas Castan via Scopus - Elsevier

Upstream Processing Equipment

Biopharmaceutical Processing: Development, Design, and Implementation of Manufacturing Processes
2018 | Book chapter
EID:

2-s2.0-85054383771

Contributors: Clapp, K.P.; Castan, A.; Lindskog, E.K.
Source: Self-asserted source
Andreas Castan via Scopus - Elsevier

Biphasic cultivation strategy to avoid Epo-Fc aggregation and optimize protein expression

Journal of Biotechnology
2016 | Journal article
EID:

2-s2.0-84963626465

Part of ISSN: 18734863 01681656
Contributors: Kaisermayer, C.; Reinhart, D.; Gili, A.; Chang, M.; Aberg, P.-M.; Castan, A.; Kunert, R.
Source: Self-asserted source
Andreas Castan via Scopus - Elsevier

Influence of bioreactor scale and complex medium on probing control of glucose feeding in cultivations of recombinant strains of Escherichia coli

Biotechnology and Bioengineering
2007 | Journal article
EID:

2-s2.0-34447342536

Part of ISSN: 00063592 10970290
Contributors: Velut, S.; Castan, A.; Short, K.A.; Axelsson, J.P.; Hagander, P.; Zditosky, B.A.; Rysenga, C.W.; De Maré, L.; Haglund, J.
Source: Self-asserted source
Andreas Castan via Scopus - Elsevier

Oxygen enriched air supply in Escherichia coli processes: Production of biomass and recombinant human growth hormone

Enzyme and Microbial Technology
2002 | Journal article
EID:

2-s2.0-0037018873

Part of ISSN: 01410229
Contributors: Castan, A.; Näsman, A.; Enfors, S.-O.
Source: Self-asserted source
Andreas Castan via Scopus - Elsevier

The use of flow cytometry to detect nucleic acids attached to the surface of Escherichia coli in high cell density fed-batch processes

Biotechnology Letters
2002 | Journal article
EID:

2-s2.0-0036165047

Part of ISSN: 01415492
Contributors: Castan, A.; Heidrich, J.; Enfors, S.-O.
Source: Self-asserted source
Andreas Castan via Scopus - Elsevier

Formate accumulation due to DNA release in aerobic cultivations of Escherichia coli

Biotechnology and Bioengineering
2001 | Journal article
EID:

2-s2.0-0035809231

Part of ISSN: 00063592
Contributors: Castan, A.; Enfors, S.-O.
Source: Self-asserted source
Andreas Castan via Scopus - Elsevier

Characteristics of a DO-controlled fed-batch culture of Escherichia coli

Bioprocess Engineering
2000 | Journal article
EID:

2-s2.0-0033944251

Part of ISSN: 0178515X
Contributors: Castan, A.; Enfors, S.-O.
Source: Self-asserted source
Andreas Castan via Scopus - Elsevier

Influence of scale-up on the quality of recombinant human growth hormone

Biotechnology and Bioengineering
2000 | Journal article
EID:

2-s2.0-0034691773

Part of ISSN: 00063592
Contributors: Bylund, F.; Castan, A.; Mikkola, R.; Veide, A.; Larsson, G.
Source: Self-asserted source
Andreas Castan via Scopus - Elsevier