Personal information

United Kingdom

Activities

Employment (4)

University of Nottingham: Nottingham, Nottinghamshire, GB

2019-08-01 to present | Professor (School of Life Sciences)
Employment
Source: Self-asserted source
Matthew Loose

University of Nottingham: Nottingham, Nottingham, GB

2015-08-01 to present | Associate Professor (Life Sciences)
Employment
Source: Self-asserted source
Matthew Loose

University of Nottingham: Nottingham, Nottingham, GB

2013-09-01 to present | Deep Seq Academic Lead (Life Sciences )
Employment
Source: Self-asserted source
Matthew Loose

University of Nottingham: Nottingham, Nottingham, GB

2007-11-01 to present | Lecturer (Life Sciences)
Employment
Source: Self-asserted source
Matthew Loose

Education and qualifications (2)

King's College London: London, London, GB

1997-09 to 2001-05 | PhD (Randall Institue)
Education
Source: Self-asserted source
Matthew Loose

University of Cambridge: Cambridge, Cambridgeshire, GB

1994-10 to 1997-06 | Natural Sciences Hons (Genetics)
Education
Source: Self-asserted source
Matthew Loose

Funding (15)

A New Durable Read EXtension Method for Very, Very Long Reads

2019-01-01 to 2021-12-31 | Grant
Wellcome Trust (London, GB)
GRANT_NUMBER:

212965/Z/18/Z

Source: Self-asserted source
Matthew Loose via DimensionsWizard

Cell fate regulation during gastrulation in humans and pigs

2018-09-30 to 2021-09-29 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
GRANT_NUMBER: BB/S000178/1
Source: Self-asserted source
Matthew Loose via DimensionsWizard

From Comparative Genomics to Comparative Genetics - What is Required for Life Without DNA Replication Origins?

Source: Self-asserted source
Matthew Loose via DimensionsWizard

Development and applications for long read sequencing in the Midlands

Source: Self-asserted source
Matthew Loose via DimensionsWizard

Sequencing and assembling microbial community metagenomes in real-time

Source: Self-asserted source
Matthew Loose via DimensionsWizard

How does signaling induce human primordial germ cells?

Source: Self-asserted source
Matthew Loose via DimensionsWizard

Bilateral NSF/BIO-BBSRC- Remodelling Replication Roadblocks: Regulatory Systems that Integrate DNA Replication, Recombination and Protein Modification

Source: Self-asserted source
Matthew Loose via DimensionsWizard
grade
Preferred source (of 2)‎

Adaptive sampling ('Read Until') methods in optimised nanopore sequencing technologies

Source: Self-asserted source
Matthew Loose via DimensionsWizard

Studying potential interplay between active demethylation and WT1-dependent transcriptional regulation during glial differentiation.

Source: Self-asserted source
Matthew Loose via DimensionsWizard
grade
Preferred source (of 2)‎

Zika: Open genomic surveillance of Zika virus in Brazil using a novel portable real-time sequencing device

Source: Self-asserted source
Matthew Loose via DimensionsWizard
grade
Preferred source (of 2)‎

minoTour: A real time analysis and data management platform for Oxford Nanopore minION reads.

2015-03-31 to 2016-09-29 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
GRANT_NUMBER: BB/M020061/1
GRANT_NUMBER: BB/M020061/1
Source: Self-asserted source
Matthew Loose via DimensionsWizard

High throughput intermediate scale sequencing for the Midlands

2014-12-08 to 2015-12-07 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
GRANT_NUMBER: BB/M012336/1
GRANT_NUMBER: BB/M012336/1
Source: Self-asserted source
Matthew Loose via DimensionsWizard

The Role of Nanog in Establishment and Patterning of Embryonic Pluripotency

2014-03-30 to 2017-03-29 | Grant
Medical Research Council (Swindon, GB)
GRANT_NUMBER: MR/L001047/1
GRANT_NUMBER: MR/L001047/1
Source: Self-asserted source
Matthew Loose via DimensionsWizard
grade
Preferred source (of 3)‎

Establishing the GRN for the Germ Line Mesoderm of Axolotl Embryos

Source: Self-asserted source
Matthew Loose via DimensionsWizard
grade
Preferred source (of 3)‎

Regulatory networks underlying lens development and evolution

2006-07-31 to 2010-01-31 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
GRANT_NUMBER: BB/D018579/1
GRANT_NUMBER: BB/D018579/1
Source: Self-asserted source
Matthew Loose via DimensionsWizard

Works (50 of 86)

Items per page:
Page 1 of 2

FindingNemo: A Toolkit for DNA Extraction, Library Preparation and Purification for Ultra Long Nanopore Sequencing

2024-08-18 | Preprint
Contributors: Inswasti Cahyani; John Tyson; Nadine Holmes; Josh Quick; Chris Moore; Nick Loman; Matthew Loose
Source: check_circle
Crossref

Icarust, a real-time simulator for Oxford Nanopore adaptive sampling

Bioinformatics
2024-03-29 | Journal article
Contributors: Rory Munro; Satrio Wibowo; Alexander Payne; Matthew Loose; Can Alkan
Source: check_circle
Crossref

FindingNemo (v.kit14): A Toolkit for DNA Extraction, Library Preparation and Purification for Ultra Long Nanopore Sequencing v1

2024-03-12 | Preprint
Contributors: Inswasti Cahyani; John Tyson; Nadine Holmes; Josh Quick; Nicholas Loman; Matthew Loose
Source: check_circle
Crossref

ROBIN: A unified nanopore-based sequencing assay integrating real-time, intraoperative methylome classification and next-day comprehensive molecular brain tumour profiling for ultra-rapid tumour diagnostics v1

2024-01-08 | Preprint
Contributors: Simon Deacon; Inswasti Cahyani; Matthew Loose
Source: check_circle
Crossref

COMPARISON BETWEEN SANGER, ILLUMINA AND NANOPORE SEQUENCING EVIDENCING INTRA-HOST VARIATION OF FELINE LEUKEMIA VIRUS THAT INFECTS DOMESTIC CATS

2023-11-02 | Preprint
Contributors: Cristobal Castillo-Aliaga; Adam Mark Blanchard; Susana Castro-Seriche; Ezequiel Hidalgo-Hermoso; Alonso Jerez-Morales; Matthew W Loose; Rachael E Tarlinton
Source: check_circle
Crossref

Dynamic, adaptive sampling during nanopore sequencing using Bayesian experimental design

Nature Biotechnology
2023-07 | Journal article
Contributors: Lukas Weilguny; Nicola De Maio; Rory Munro; Charlotte Manser; Ewan Birney; Matthew Loose; Nick Goldman
Source: check_circle
Crossref

Sarbecoviruses of British horseshoe bats; sequence variation and epidemiology

Journal of General Virology
2023-06-14 | Journal article
Contributors: Ternenge Apaa; Amy J. Withers; Ceri Staley; Adam Blanchard; Malcolm Bennett; Samantha Bremner-Harrison; Elizabeth A. Chadwick; Frank Hailer; Stephen W. R. Harrison; Matthew Loose et al.
Source: check_circle
Crossref

Icarust, a real-time simulator for Oxford Nanopore adaptive sampling

2023-05-18 | Preprint
Contributors: Rory Munro; Alexander Payne; Matthew Loose
Source: check_circle
Crossref

Genomics and biochemical analyses reveal a metabolon key to β-L-ODAP biosynthesis in Lathyrus sativus

OpenAlex
2023-02-16 | Other
Contributors: Anne Edwards; Isaac Njaci; Abhimanyu Sarkar; Zhouqian Jiang; Gemy Kaithakottil; Chris Moore; Jitender Cheema; Clare Stevenson; Martin Rejzek; Petr Novak et al.
Source: check_circle
DataCite

Genomics and biochemical analyses reveal a metabolon key to β-L-ODAP biosynthesis in Lathyrus sativus

OpenAlex
2023-02-16 | Other
Contributors: Anne Edwards; Isaac Njaci; Abhimanyu Sarkar; Zhouqian Jiang; Gemy Kaithakottil; Chris Moore; Jitender Cheema; Clare Stevenson; Martin Rejzek; Petr Novak et al.
Source: check_circle
DataCite

Sarbecoviruses of British Horseshoe Bats; Sequence Variation and Epidemiology

2023-02-14 | Preprint
Contributors: Ternenge Apaa; Amy J. Withers; Ceri Staley; Adam Blanchard; Malcolm Bennett; Samantha Bremner-Harrison; Elizabeth A. Chadwick; Frank Hailer; Stephen W.R. Harrison; Mathew Loose et al.
Source: check_circle
Crossref

Genome Reference Assembly for Bottlenecked Southern Australian Koalas

Genome Biology and Evolution
2023-01-04 | Journal article
Contributors: Adam Mark Blanchard; Richard David Emes; Alex David Greenwood; Nadine Holmes; Matthew William Loose; Gail Katherine McEwen; Joanne Meers; Natasha Speight; Rachael Eugenie Tarlinton; Bonnie Fraser
Source: check_circle
Crossref

minoTour, real-time monitoring and analysis for nanopore sequencers

Bioinformatics
2022-01-27 | Journal article
Contributors: Rory Munro; Roberto Santos; Alexander Payne; Teri Forey; Solomon Osei; Nadine Holmes; Matthew Loose; Can Alkan
Source: check_circle
Crossref

The genome sequence of the European golden eagle, Aquila chrysaetos chrysaetos Linnaeus 1758.

Apollo - University of Cambridge Repository
2021-12-15 | Journal article
Contributors: Daniel Mead; Rob Ogden; Anna Meredith; Gabriela Peniche; Michelle Smith; Craig Corton; Karen Oliver; Jason Skelton; Emma Betteridge; Jale Dolucan et al.
Source: check_circle
DataCite

Barcode aware adaptive sampling for GridION and PromethION Oxford Nanopore sequencers

2021-12-01 | Preprint
Contributors: Alexander Payne; Rory Munro; Nadine Holmes; Christopher Moore; Matt Carlile; Matthew Loose
Source: check_circle
Crossref

Real-time monitoring and analysis of SARS-CoV-2 nanopore sequencing with minoTour

2021-09-13 | Other
Contributors: Rory Munro; Nadine Holmes; Christopher Moore; Matt Carlile; Alexander Payne; Roberto Santos; Matt Loose
Source: check_circle
Crossref

MinoTour, real-time monitoring and analysis for Nanopore Sequencers

2021-09-12 | Other
Contributors: Rory Munro; Roberto Santos; Alexander Payne; Teri Forey; Solomon Osei; Nadine Holmes; Matt Loose
Source: check_circle
Crossref

FindingNemo Extraction 2: Phenol-free Method v2

2021-09-03 | Preprint
Contributors: Inswasti Cahyani; John Tyson; Nadine Holmes; Josh Quick; Nicholas Loman; Matthew Loose
Source: check_circle
Crossref

FindingNemo: A Toolkit of CoHex- and Glass Bead-based Protocols for Ultra-Long Sequencing on ONT Platforms v1

2021-09-02 | Preprint
Contributors: Inswasti Cahyani; John Tyson; Nadine Holmes; Josh Quick; Nicholas Loman; Matthew Loose
Source: check_circle
Crossref

FindingNemo Extraction 2: Phenol-free Method v1

2021-09-01 | Preprint
Contributors: Inswasti Cahyani; John Tyson; Nadine Holmes; Josh Quick; Nicholas Loman; Matthew Loose
Source: check_circle
Crossref

FindingNemo Extraction 3: NEB Monarch Kit v1

2021-09-01 | Preprint
Contributors: Inswasti Cahyani; John Tyson; Nadine Holmes; Josh Quick; Nicholas Loman; Matthew Loose
Source: check_circle
Crossref

FindingNemo Extraction 4: Circulomics Kit v1

2021-09-01 | Preprint
Contributors: Inswasti Cahyani; John Tyson; Nadine Holmes; Josh Quick; Nicholas Loman; Matthew Loose
Source: check_circle
Crossref

FindingNemo Library 2: Modified RAD004 v1

2021-09-01 | Preprint
Contributors: Inswasti Cahyani; John Tyson; Nadine Holmes; Josh Quick; Nicholas Loman; Matthew Loose
Source: check_circle
Crossref

FindingNemo Library 3: KrazyStarFish (KSF) v1

2021-09-01 | Preprint
Contributors: John Tyson; Inswasti Cahyani; Nadine Holmes; Josh Quick; Nicholas Loman; Matthew Loose
Source: check_circle
Crossref

FindingNemo in OneDay: Ultra-Long ONT Library Preparation from Cell to Flowcell in One Day v1

2021-08-19 | Preprint
Contributors: Inswasti Cahyani; John Tyson; Nadine Holmes; Josh Quick; Nicholas Loman; Matthew Loose
Source: check_circle
Crossref

FindingNemo Library 1: Modified ULK001 v1

2021-08-19 | Preprint
Contributors: Inswasti Cahyani; John Tyson; Nadine Holmes; Josh Quick; Nicholas Loman; Matthew Loose
Source: check_circle
Crossref

FindingNemo Extraction 1: Phenol-based Method v1

2021-08-18 | Preprint
Contributors: Inswasti Cahyani; John Tyson; Nadine Holmes; Josh Quick; Nicholas Loman; Matthew Loose
Source: check_circle
Crossref

Genome Profiling of SARS-CoV-2 in Indonesia, ASEAN, and the Neighbouring East Asian Countries: Features, Challenges, and Achievements

2021-07-07 | Other
Contributors: Inswasti Cahyani; Eko W. Putro; Asep M. Ridwanuloh; Satrio H.B. Wibowo; Hariyatun Hariyatun; Gita Syahputra; Gilang Akbariani; Ahmad R. Utomo; Mohammad Ilyas; Matthew W. Loose et al.
Source: check_circle
Crossref

The genome sequence of the European golden eagle, Aquila chrysaetos chrysaetos Linnaeus 1758 [version 1; peer review: 3 approved]

2021-05-14 | Journal article
Part of ISSN: 2398-502X
Contributors: Dan Mead; Rob Ogden; Anna Meredith; Gabriela Peniche; Michelle Smith; Craig Corton; Karen Oliver; Jason Skelton; Emma Betteridge; Jale Doulcan et al.
Source: check_circle
Wellcome Open Research

Readfish enables targeted nanopore sequencing of gigabase-sized genomes

Nature Biotechnology
2021-04 | Journal article
Contributors: Alexander Payne; Nadine Holmes; Thomas Clarke; Rory Munro; Bisrat J. Debebe; Matthew Loose
Source: check_circle
Crossref

Potent anti-SARS-CoV-2 Antibody Responses are Associated with Better Prognosis in Hospital Inpatient COVID-19 Disease

2020-08-24 | Other
Contributors: Patrick J. Tighe; Richard A. Urbanowicz; C. Lucy Fairclough; C. Patrick McClure; Brian J. Thomson; Nancy Gomez; Joseph G. Chappell; Theocharis Tsoleridis; Matthew Loose; Matthew Carlile et al.
Source: check_circle
Crossref

Dynamic, adaptive sampling during nanopore sequencing using Bayesian experimental design

2020-02-07 | Preprint
Contributors: Lukas Weilguny; Nicola De Maio; Rory Munro; Charlotte Manser; Ewan Birney; Matt Loose; Nick Goldman
Source: check_circle
Crossref

Nanopore adaptive sequencing for mixed samples, whole exome capture and targeted panels

2020-02-03 | Preprint
Contributors: Alexander Payne; Nadine Holmes; Thomas Clarke; Rory Munro; Bisrat Debebe; Matthew Loose
Source: check_circle
Crossref

Pluripotency and X chromosome dynamics revealed in pig pre-gastrulating embryos by single cell analysis.

Apollo - University of Cambridge Repository
2019-04-09 | Journal article
Contributors: Priscila Ramos-Ibeas; Fei Sang; Qifan Zhu; Walfred Tang; Sarah Withey; Doris Klisch; Liam Wood; Matthew Loose; Azim Surani; Ramiro Alberio
Source: check_circle
DataCite

Reply to ‘Errors in long-read assemblies can critically affect protein prediction’

Nature Biotechnology
2019-02-22 | Journal article
Contributors: Sergey Koren; Adam M. Phillippy; Jared T. Simpson; Nicholas J. Loman; Matthew Loose
Source: check_circle
Crossref

Pluripotency and X chromosome dynamics revealed in pig pre-gastrulating embryos by single cell analysis

Nature Communications
2019-01-30 | Journal article
Contributors: Priscila Ramos-Ibeas; Fei Sang; Qifan Zhu; Walfred W. C. Tang; Sarah Withey; Doris Klisch; Liam Wood; Matt Loose; M. Azim Surani; Ramiro Alberio
Source: check_circle
Crossref

foxc1a and foxc1b differentially regulate angiogenesis from arteries and veins by modulating Vascular Endothelial Growth Factor signalling

2018-09-14 | Other
Contributors: Zhen Jiang; Teri Evans; Aaron M. Savage; Matthew Loose; Timothy J.A. Chico; Fredericus J.M. van Eeden; Robert N. Wilkinson
Source: check_circle
Crossref

Finding the Needle: Targeted Nanopore Sequencing and CRISPR-Cas9.

The CRISPR journal
2018-08-01 | Journal article
Source: Self-asserted source
Matthew Loose

Lineage segregation, pluripotency and X-chromosome inactivation in the pig pre-gastrulation embryo

2018-06-20 | Other
Contributors: Priscila Ramos-Ibeas; Fei Sang; Qifan Zhu; Walfred W.C. Tang; Sarah Withey; Doris Klisch; Matt Loose; M. Azim Surani; Ramiro Alberio
Source: check_circle
Crossref

Whale watching with BulkVis: A graphical viewer for Oxford Nanopore bulk fast5 files

2018-05-03 | Other
Contributors: Alexander Payne; Nadine Holmes; Vardhman Rakyan; Matthew Loose
Source: check_circle
Crossref

Publisher Correction: Virtual Genome Walking across the 32 Gb Ambystoma mexicanum genome; assembling gene models and intronic sequence

Scientific Reports
2018-04-13 | Journal article
Contributors: Teri Evans; Andrew D. Johnson; Matthew Loose
Source: check_circle
Crossref

Virtual Genome Walking across the 32 Gb Ambystoma mexicanum genome; assembling gene models and intronic sequence

Scientific Reports
2018-01-12 | Journal article
Contributors: Teri Evans; Andrew D. Johnson; Matthew Loose
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Epidemic establishment and cryptic transmission of Zika virus in Brazil and the Americas

bioRxiv
2017 | Journal article
ARXIV:

http://biorxiv.org/content/early/2017/03/27/105171.full.pdf

Source: Self-asserted source
Matthew Loose

MinION Analysis and Reference Consortium: Phase 2 data release and analysis of R9.0 chemistry.

F1000Research
2017 | Journal article
Contributors: Jain M; Tyson JR; Loose M; Ip CLC; Eccles DA; O'Grady J; Malla S; Leggett RM; Wallerman O; Jansen HJ et al.
Source: Self-asserted source
Matthew Loose via Europe PubMed Central

Multiplex PCR method for MinION and Illumina sequencing of Zika and other virus genomes directly from clinical samples

bioRxiv
2017 | Journal article
ARXIV:

http://biorxiv.org/content/early/2017/01/09/098913.full.pdf

Source: Self-asserted source
Matthew Loose

Nanopore sequencing and assembly of a human genome with ultra-long reads

bioRxiv
2017 | Journal article
ARXIV:

http://biorxiv.org/content/early/2017/04/20/128835.full.pdf

Source: Self-asserted source
Matthew Loose

The potential impact of nanopore sequencing on human genetics

Human Molecular Genetics
2017-10-01 | Journal article
Contributors: Matthew W. Loose
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Virtual Genome Walking: Generating gene models for the salamander Ambystoma mexicanum

2017-09-06 | Other
Contributors: Teri Evans; Andrew Johnson; Matt Loose
Source: check_circle
Crossref

Establishment and cryptic transmission of Zika virus in Brazil and the Americas.

2017-06 | Journal article
Contributors: Faria NR; Quick J; Claro IM; Thézé J; de Jesus JG; Giovanetti M; Kraemer MUG; Hill SC; Black A; da Costa AC et al.
Source: Self-asserted source
Matthew Loose via Europe PubMed Central

Multiplex PCR method for MinION and Illumina sequencing of Zika and other virus genomes directly from clinical samples.

2017-06 | Journal article
Contributors: Quick J; Grubaugh ND; Pullan ST; Claro IM; Smith AD; Gangavarapu K; Oliveira G; Robles-Sikisaka R; Rogers TF; Beutler NA et al.
Source: Self-asserted source
Matthew Loose via Europe PubMed Central
Items per page:
Page 1 of 2

Peer review (11 reviews for 9 publications/grants)

Review activity for BMC biology. (1)
Review activity for BMC genomics (1)
Review activity for Communications medicine. (1)
Review activity for Nature (1)
Review activity for Nature biomedical engineering. (1)
Review activity for Nature biotechnology. (1)
Review activity for Nature communications (3)
Review activity for Nature methods. (1)
Review activity for Nature reviews. (1)