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Employment (4)

French National Center for Scientific Research (CNRS): Paris, FR : Paris, France, FR

2021-01-01 to present | Research Director Emeritus (University of Paris Faculty of Fundamental and Biomedical Sciences)
Employment
Source: Self-asserted source
Francine Acher

French National Center for Scientific Research (CNRS): Paris, FR

1999-10-01 to 2020-12-31 | Research Director (Department of Chemistry)
Employment
Source: Self-asserted source
Francine Acher

French National Center for Scientific Research (CNRS): Paris, FR

1981-10 to 1999-09 | Research Associate (Department of Chemistry)
Employment
Source: Self-asserted source
Francine Acher

French National Center for Scientific Research (CNRS): Berkeley, California, US

1984-05 to 1985-09 | Research Fellow (Department of Chemistry,University of California)
Employment
Source: Self-asserted source
Francine Acher

Education and qualifications (3)

University Paris VI: Paris, FR

1979-09 to 1984-05 | PhD (Bioorganic Chemistry)
Education
Source: Self-asserted source
Francine Acher

University Paris VI : Paris, FR

1978-09 to 1979-06 | Master’s degree (Organic Chemistry)
Education
Source: Self-asserted source
Francine Acher

Strasbourg Higher Education School of Chemistry: Strasbourg, FR

1975-09 to 1978-07 | Equiv. M.SC
Education
Source: Self-asserted source
Francine Acher

Works (15)

Epitope Identification of an mGlu5 Receptor Nanobody Using Physics-Based Molecular Modeling and Deep Learning Techniques

Journal of Chemical Information and Modeling
2024-06-10 | Journal article
Contributors: Floriane Eshak; Léo Pion; Pauline Scholler; Damien Nevoltris; Patrick Chames; Philippe Rondard; Jean-Philippe Pin; Francine C. Acher; Anne Goupil-Lamy
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Crossref

Design, Synthesis, Pharmacology, and In Silico Studies of (1S,2S,3S)-2-((S)-Amino(carboxy)methyl)-3-(carboxymethyl)cyclopropane-1-carboxylic Acid (LBG30300): A Picomolar Potency Subtype-Selective mGlu2 Receptor Agonist

Journal of Medicinal Chemistry
2024-01-25 | Journal article
Contributors: Na Liu; Floriane Eshak; Fanny Malhaire; Isabelle Brabet; Laurent Prézeau; Emma Renard; Jean-Philippe Pin; Francine C. Acher; Markus Staudt; Lennart Bunch
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Crossref

Metabotropic glutamate receptors in GtoPdb v.2023.1

IUPHAR/BPS Guide to Pharmacology CITE
2023-04-26 | Journal article
Contributors: Francine Acher; Giuseppe Battaglia; Hans Bräuner-Osborne; P. Jeffrey Conn; Robert Duvoisin; Francesco Ferraguti; Peter J. Flor; Cyril Goudet; Karen J. Gregory; David Hampson et al.
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Crossref

Data from Infiltrating Myeloid Cells Drive Osteosarcoma Progression via GRM4 Regulation of IL23

2023-04-03 | Preprint
Contributors: Maya Kansara; Kristian Thomson; Puiyi Pang; Aurelie Dutour; Lisa Mirabello; Francine Acher; Jean-Philippe Pin; Elizabeth G. Demicco; Juming Yan; Michele W.L. Teng et al.
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Crossref

Data from Infiltrating Myeloid Cells Drive Osteosarcoma Progression via GRM4 Regulation of IL23

2023-04-03 | Preprint
Contributors: Maya Kansara; Kristian Thomson; Puiyi Pang; Aurelie Dutour; Lisa Mirabello; Francine Acher; Jean-Philippe Pin; Elizabeth G. Demicco; Juming Yan; Michele W.L. Teng et al.
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Crossref

Supplementary Data from Infiltrating Myeloid Cells Drive Osteosarcoma Progression via GRM4 Regulation of IL23

2023-04-03 | Preprint
Contributors: Maya Kansara; Kristian Thomson; Puiyi Pang; Aurelie Dutour; Lisa Mirabello; Francine Acher; Jean-Philippe Pin; Elizabeth G. Demicco; Juming Yan; Michele W.L. Teng et al.
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Crossref

Supplementary Data from Infiltrating Myeloid Cells Drive Osteosarcoma Progression via GRM4 Regulation of IL23

2023-04-03 | Preprint
Contributors: Maya Kansara; Kristian Thomson; Puiyi Pang; Aurelie Dutour; Lisa Mirabello; Francine Acher; Jean-Philippe Pin; Elizabeth G. Demicco; Juming Yan; Michele W.L. Teng et al.
Source: check_circle
Crossref

Metabotropic glutamate receptor orthosteric ligands and their binding sites

Neuropharmacology
2022-02 | Journal article
Contributors: Francine C. Acher; Alexandre Cabayé; Floriane Eshak; Anne Goupil-Lamy; Jean-Philippe Pin
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Crossref

Metabotropic glutamate receptors in GtoPdb v.2021.3

IUPHAR/BPS Guide to Pharmacology CITE
2021-09-02 | Journal article
Contributors: Francine Acher; Giuseppe Battaglia; Hans Bräuner-Osborne; P. Jeffrey Conn; Robert Duvoisin; Francesco Ferraguti; Peter J. Flor; Cyril Goudet; Karen J. Gregory; David Hampson et al.
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Crossref

A nanobody activating metabotropic glutamate receptor 4 discriminates between homo- and heterodimers

Proceedings of the National Academy of Sciences
2021-08-17 | Journal article
Contributors: Jordi Haubrich; Joan Font; Robert B. Quast; Anne Goupil-Lamy; Pauline Scholler; Damien Nevoltris; Francine Acher; Patrick Chames; Philippe Rondard; Laurent Prézeau et al.
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Crossref

Illuminating the allosteric modulation of the calcium-sensing receptor

Proceedings of the National Academy of Sciences
2020-09 | Journal article
Contributors: Hongkang Liu; Ping Yi; Wenjing Zhao; Yuling Wu; Francine Acher; Jean-Philippe Pin; Jianfeng Liu; Philippe Rondard
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Crossref

Asc-1 Transporter (SLC7A10): Homology Models And Molecular Dynamics Insights Into The First Steps Of The Transport Mechanism

Scientific Reports
2020-02-28 | Journal article
Contributors: Afaf Mikou; Alexandre Cabayé; Anne Goupil; Hugues-Olivier Bertrand; Jean-Pierre Mothet; Francine C. Acher
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Crossref

Conformational pathway provides unique sensitivity to a synaptic mGluR

Nature Communications
2019-12-05 | Journal article
Contributors: Chris H. Habrian; Joshua Levitz; Vojtech Vyklicky; Zhu Fu; Adam Hoagland; Isabelle McCort-Tranchepain; Francine Acher; Ehud Y. Isacoff
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Crossref

Infiltrating Myeloid Cells Drive Osteosarcoma Progression via GRM4 Regulation of IL23

Cancer Discovery
2019-11-01 | Journal article
Contributors: Maya Kansara; Kristian Thomson; Puiyi Pang; Aurelie Dutour; Lisa Mirabello; Francine Acher; Jean-Philippe Pin; Elizabeth G. Demicco; Juming Yan; Michele W.L. Teng et al.
Source: check_circle
Crossref

Metabotropic glutamate receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

IUPHAR/BPS Guide to Pharmacology CITE
2019-09-16 | Journal article
Contributors: Francine Acher; Giuseppe Battaglia; Hans Bräuner-Osborne; P. Jeffrey Conn; Robert Duvoisin; Francesco Ferraguti; Peter J. Flor; Cyril Goudet; Karen J. Gregory; David Hampson et al.
Source: check_circle
Crossref

Peer review (8 reviews for 4 publications/grants)

Review activity for ACS chemical neuroscience. (2)
Review activity for Journal of chemical information and modeling. (1)
Review activity for Journal of medicinal chemistry. (4)
Review activity for Nature communications (1)