Personal information

Macrophages, Cell Death, Cytokines, Biomaterials
United States

Activities

Works (27)

STRIvE-02: A First-in-Human Phase I Study of Systemically Administered B7-H3 Chimeric Antigen Receptor T Cells for Patients With Relapsed/Refractory Solid Tumors.

Journal of Clinical Oncology
2024-09-10 | Journal article
Contributors: Navin Pinto; Catherine M Albert; Mallory R Taylor; Heidi B Ullom; Ashley L Wilson; Wenjun Huang; Jason Wendler; Sowmya Pattabhi; Kristy Seidel; Christopher Brown et al.
Source: check_circle
Dimensions

Development of a Novel Solid Tumor-Bearing Humanized Animal Model for Simultaneously Evaluating the Toxicity and Efficacy of Bispecific T Cell Engager

Blood
2023-11-02 | Journal article
Part of ISSN: 1528-0020
Contributors: Guoxiang Yang; Li-Chin Yao; Heather Gustafson; James G Keck; Mingshan Cheng
Source: Self-asserted source
Heather H Gustafson via Crossref Metadata Search

PBMC-Humanized Mouse Model to Assess Individual Variability in Efficacy and Toxicity of Universal CD19 Chimeric Antigen Receptor T Cell Immunotherapy

Blood
2023-11-02 | Journal article
Part of ISSN: 1528-0020
Contributors: Won Lee; Destanie Rose; Heather Gustafson; Meredith Jackson; Kamila Gwiazda; Joshua Gustafson; Mariliis Ott; Rebecca Gardner; James G Keck; Jiwon Yang
Source: Self-asserted source
Heather H Gustafson via Crossref Metadata Search

Abstract 4096: Assessing individual variability in efficacy and toxicity of autologous and allogeneic chimeric antigen receptor T-cell immunotherapy using a PBMC-humanized mouse model

Cancer Research
2023-04-04 | Journal article
Part of ISSN: 1538-7445
Contributors: Won Lee; Destanie Rose; Katelyn Burleigh; Blair Armstrong; Heather Gustafson; Rebecca Gardner; James G. Keck; Jiwon Yang
Source: Self-asserted source
Heather H Gustafson via Crossref Metadata Search

382 A novel peripheral blood mononuclear cell humanized mouse model for preclinical efficacy and toxicity evaluation of chimeric antigen receptor T-cell immunotherapy

Regular and Young Investigator Award Abstracts
2022-11 | Conference paper
Contributors: Jiwon Yang; Won Lee; Heather Gustafson; Blair Amrstrong; Katelym Burleigh; Mingshan Cheng; James Keck
Source: Self-asserted source
Heather H Gustafson via Crossref Metadata Search

In Vivo PBMC-Humanized Mouse Model to Assess Individual Variability in Efficacy and Toxicity of Autologous and Allogeneic Chimeric Antigen Receptor T-Cell Immunotherapy

Blood
2022-11-15 | Journal article
Part of ISSN: 1528-0020
Contributors: Won Lee; Destanie Rose; Mingshan Cheng; Heather Gustafson; Rebecca A Gardner; James G Keck; Jiwon Yang
Source: Self-asserted source
Heather H Gustafson via Crossref Metadata Search

Abstract 2816: A novel <i>in vivo</i> model to simultaneously assess efficacy and toxicity of chimeric antigen receptor T-cell immunotherapy

Cancer Research
2022-06-15 | Journal article
Part of ISSN: 1538-7445
Contributors: Jiwon Yang; Won Lee; Jing Jiao; Danying Cai; Heather Gustafson; Rebecca Gardner; Mingshan Cheng; James G. Keck
Source: Self-asserted source
Heather H Gustafson via Crossref Metadata Search

Poor Clinical Outcome in Pediatric Immunotherapy Is Mediated By a Pre-Existing Overactive IL-18-IFNy Immune Phenotype

Blood
2021-11-05 | Journal article
Part of ISSN: 1528-0020
Contributors: Katelyn Burleigh; Anna Kus; Alice Long; Michael C. Jensen; Seth Masters; James E Vince; Bobbie-Jo Webb-Robertson; Rebecca A Gardner; Heather Gustafson
Source: Self-asserted source
Heather H Gustafson via Crossref Metadata Search

The Cancer Microbiome: Distinguishing Direct and Indirect Effects Requires a Systemic View

Trends in Cancer
2020 | Journal article
EID:

2-s2.0-85079050303

Part of ISBN:

24058033

Contributors: Xavier, J.B.; Young, V.B.; Skufca, J.; Ginty, F.; Testerman, T.; Pearson, A.T.; Macklin, P.; Mitchell, A.; Shmulevich, I.; Xie, L. et al.
Source: Self-asserted source
Heather H Gustafson via Scopus - Elsevier

Trajectory analysis quantifies transcriptional plasticity during macrophage polarization

Scientific Reports
2020-12 | Journal article
Part of ISSN: 2045-2322
Source: Self-asserted source
Heather H Gustafson

Identification of a DNA Aptamer That Binds to Human Monocytes and Macrophages

Bioconjugate Chemistry
2020-08-19 | Journal article
Part of ISSN: 1043-1802
Part of ISSN: 1520-4812
Source: Self-asserted source
Heather H Gustafson

Current state of in vivo panning technologies: Designing specificity and affinity into the future of drug targeting

Advanced Drug Delivery Reviews
2018 | Journal article
EID:

2-s2.0-85049351937

Contributors: Gustafson, H.H.; Olshefsky, A.; Sylvestre, M.; Sellers, D.L.; Pun, S.H.
Source: Self-asserted source
Heather H Gustafson via Scopus - Elsevier

Instructing macrophages to fight cancer

Nature Biomedical Engineering
2018 | Journal article
EID:

2-s2.0-85052053422

Contributors: Gustafson, H.H.; Pun, S.H.
Source: Self-asserted source
Heather H Gustafson via Scopus - Elsevier

Reversibly Switchable, pH-Dependent Peptide Ligand Binding via 3,5-Diiodotyrosine Substitutions

ACS Chemical Biology
2018 | Journal article
EID:

2-s2.0-85045850888

Contributors: Ngambenjawong, C.; Sylvestre, M.; Gustafson, H.H.; Pineda, J.M.B.; Pun, S.H.
Source: Self-asserted source
Heather H Gustafson via Scopus - Elsevier

Serum Nuclease Susceptibility of mRNA Cargo in Condensed Polyplexes

Molecular Pharmaceutics
2018 | Journal article
EID:

2-s2.0-85046258247

Contributors: Yen, A.; Cheng, Y.; Sylvestre, M.; Gustafson, H.H.; Puri, S.; Pun, S.H.
Source: Self-asserted source
Heather H Gustafson via Scopus - Elsevier

Evolution of a designed protein assembly encapsulating its own RNA genome

Nature
2017 | Journal article
EID:

2-s2.0-85040008738

Contributors: Butterfield, G.L.; Lajoie, M.J.; Gustafson, H.H.; Sellers, D.L.; Nattermann, U.; Ellis, D.; Bale, J.B.; Ke, S.; Lenz, G.H.; Yehdego, A. et al.
Source: Self-asserted source
Heather H Gustafson via Scopus - Elsevier

Progress in tumor-associated macrophage (TAM)-targeted therapeutics

Advanced Drug Delivery Reviews
2017 | Journal article
EID:

2-s2.0-85018922906

Contributors: Ngambenjawong, C.; Gustafson, H.H.; Pun, S.H.
Source: Self-asserted source
Heather H Gustafson via Scopus - Elsevier

A Facile Cyclization Method Improves Peptide Serum Stability and Confers Intrinsic Fluorescence

ChemBioChem
2017-12-14 | Journal article
Contributors: Chayanon Ngambenjawong; Heather H. Gustafson; Meilyn Sylvestre; Suzie H. Pun
Source: check_circle
Crossref

Serum stability and affinity optimization of an M2 macrophage-targeting peptide (M2pep)

Theranostics
2016 | Journal article
EID:

2-s2.0-84991573177

Contributors: Ngambenjawong, C.; Gustafson, H.H.; Pineda, J.M.; Kacherovsky, N.A.; Cieslewicz, M.; Pun, S.H.
Source: Self-asserted source
Heather H Gustafson via Scopus - Elsevier

Synthetic and toxicological characteristics of silica nanomaterials for imaging and drug delivery applications

Nanobiomaterials Handbook
2016 | Book chapter
EID:

2-s2.0-85051448922

Contributors: Herd, H.; Ghandehari, H.
Source: Self-asserted source
Heather H Gustafson via Scopus - Elsevier

Macrophage silica nanoparticle response is phenotypically dependent

Biomaterials
2015 | Journal article
EID:

2-s2.0-84927939169

Contributors: Herd, H.L.; Bartlett, K.T.; Gustafson, J.A.; McGill, L.D.; Ghandehari, H.
Source: Self-asserted source
Heather H Gustafson via Scopus - Elsevier

Nanoparticle uptake: The phagocyte problem

Nano Today
2015 | Journal article
EID:

2-s2.0-84949322229

Contributors: Gustafson, H.H.; Holt-Casper, D.; Grainger, D.W.; Ghandehari, H.
Source: Self-asserted source
Heather H Gustafson via Scopus - Elsevier

Nanoparticle geometry and surface orientation influence mode of cellular uptake

ACS Nano
2013 | Journal article
EID:

2-s2.0-84875685339

Contributors: Herd, H.; Daum, N.; Jones, A.T.; Huwer, H.; Ghandehari, H.; Lehr, C.-M.
Source: Self-asserted source
Heather H Gustafson via Scopus - Elsevier

Transcriptional responses of human aortic endothelial cells to nanoconstructs used in biomedical applications

Molecular Pharmaceutics
2013 | Journal article
EID:

2-s2.0-84881363943

Contributors: Moos, P.J.; Honeggar, M.; Malugin, A.; Herd, H.; Thiagarajan, G.; Ghandehari, H.
Source: Self-asserted source
Heather H Gustafson via Scopus - Elsevier

Size and surface charge significantly influence the toxicity of silica and dendritic nanoparticles

Nanotoxicology
2012 | Journal article
EID:

2-s2.0-84867528048

Contributors: Greish, K.; Thiagarajan, G.; Herd, H.; Price, R.; Bauer, H.; Hubbard, D.; Burckle, A.; Sadekar, S.; Yu, T.; Anwar, A. et al.
Source: Self-asserted source
Heather H Gustafson via Scopus - Elsevier

Differential toxicity of amorphous silica nanoparticles toward phagocytic and epithelial cells

Journal of Nanoparticle Research
2011 | Journal article
EID:

2-s2.0-80955158655

Contributors: Malugin, A.; Herd, H.; Ghandehari, H.
Source: Self-asserted source
Heather H Gustafson via Scopus - Elsevier

Silica nanoconstruct cellular toleration threshold in vitro

Journal of Controlled Release
2011 | Journal article
EID:

2-s2.0-79960108621

Contributors: Herd, H.L.; Malugin, A.; Ghandehari, H.
Source: Self-asserted source
Heather H Gustafson via Scopus - Elsevier