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Works (29)

GWAS-identified bipolar disorder risk allele in the FADS1/2 gene region links mood episodes and unsaturated fatty acid metabolism in mutant mice

Molecular Psychiatry
2023-07 | Journal article
Contributors: Hirona Yamamoto; Hyeon-Cheol Lee-Okada; Masashi Ikeda; Takumi Nakamura; Takeo Saito; Atsushi Takata; Takehiko Yokomizo; Nakao Iwata; Tadafumi Kato; Takaoki Kasahara
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Crossref

The UFM1 system regulates ER-phagy through the ufmylation of CYB5R3

Nature Communications
2022-12-21 | Journal article
Contributors: Ryosuke Ishimura; Afnan H. El-Gowily; Daisuke Noshiro; Satoko Komatsu-Hirota; Yasuko Ono; Mayumi Shindo; Tomohisa Hatta; Manabu Abe; Takefumi Uemura; Hyeon-Cheol Lee-Okada et al.
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Crossref

Omega-6 highly unsaturated fatty acids in Leydig cells facilitate male sex hormone production

Communications Biology
2022-09-21 | Journal article
Contributors: Keiken Ri; Hyeon-Cheol Lee-Okada; Takehiko Yokomizo
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Crossref

A Western Diet Alters Skin Ceramides and Compromises the Skin Barrier in Ears

Journal of Investigative Dermatology
2022-07 | Journal article
Contributors: Kahbing Jasmine Tan; Satoshi Nakamizo; Hyeon-Cheol Lee-Okada; Reiko Sato; Zachary Chow; Saeko Nakajima; John E.A. Common; Kazuko Saeki; Takehiko Yokomizo; Florent Ginhoux et al.
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Crossref

FTY720 requires vitamin B12-TCN2-CD320 signaling in astrocytes to reduce disease in an animal model of multiple sclerosis

2022-01-12 | Preprint
Contributors: Deepa Jonnalagadda; Yasuyuki Kihara; Aran Groves; Manisha Ray; Arjun Saha; Hyeon-Cheol Lee-Okada; Tomomi Furihata; Takehiko Yokomizo; Edward V. Quadros; Richard Rivera et al.
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Crossref

Dietary intake of n-3 polyunsaturated fatty acids alters the lipid mediator profile of the kidney but does not attenuate renal insufficiency

Biochemical and Biophysical Research Communications
2021-12 | Journal article
Contributors: Ryotaro Shioda; Airi Jo-Watanabe; Hyeon-Cheol Lee-Okada; Ken Yasukawa; Toshiaki Okuno; Yusuke Suzuki; Takehiko Yokomizo
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Crossref

Development of a liquid chromatography–electrospray ionization tandem mass spectrometric method for the simultaneous analysis of free fatty acids

The Journal of Biochemistry
2021-10-12 | Journal article
Contributors: Hyeon-Cheol Lee-Okada; Kotaro Hama; Kazuaki Yokoyama; Takehiko Yokomizo
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Crossref

Ablation of fatty acid desaturase 2 (FADS2) exacerbates hepatic triacylglycerol and cholesterol accumulation in polyunsaturated fatty acid‐depleted mice

FEBS Letters
2021-07 | Journal article
Contributors: Yuri Hayashi; Hyeon‐Cheol Lee‐Okada; Eri Nakamura; Norihiro Tada; Takehiko Yokomizo; Yoko Fujiwara; Ikuyo Ichi; László Nagy
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Crossref

Combined use of irinotecan and p53 activator enhances growth inhibition of mesothelioma cells

FEBS Open Bio
2020-11 | Journal article
Contributors: Bo Han; Hyeon‐Cheol Lee‐Okada; Momoko Ishimine; Hajime Orita; Keiko Nishikawa; Tetsuya Takagaki; Kazunori Kajino; Takehiko Yokomizo; Okio Hino; Toshiyuki Kobayashi
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Crossref

Aging exacerbates high‐fat diet‐induced steatohepatitis through alteration in hepatic lipid metabolism in mice

Journal of Gastroenterology and Hepatology
2020-08 | Journal article
Contributors: Kei Ishizuka; Kazuyoshi Kon; Hyeon‐Cheol Lee‐Okada; Kumiko Arai; Akira Uchiyama; Shunhei Yamashina; Takehiko Yokomizo; Kenichi Ikejima
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Crossref

Carboxylesterase 2: A Key Enzyme in Drug and Prodrug Metabolism

Juntendo Medical Journal
2020-04-30 | Journal article
Part of ISSN: 2187-9737
Part of ISSN: 2188-2126
Source: Self-asserted source
Hyeon-Cheol Lee-Okada

Metabolomic profiling of gastric cancer tissues identified potential biomarkers for predicting peritoneal recurrence

Gastric Cancer
2020-03-26 | Journal article
Part of ISSN: 1436-3291
Part of ISSN: 1436-3305
Source: Self-asserted source
Hyeon-Cheol Lee-Okada

Loss of autophagy impairs physiological steatosis by accumulation of NCoR1

Life Science Alliance
2020-01 | Journal article
Contributors: Shun-saku Takahashi; Yu-Shin Sou; Tetsuya Saito; Akiko Kuma; Takayuki Yabe; Yuki Sugiura; Hyeon-Cheol Lee; Makoto Suematsu; Takehiko Yokomizo; Masato Koike et al.
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Crossref

Lipid-metabolizing serine hydrolases in the mammalian central nervous system: endocannabinoids and beyond

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids
2019 | Journal article
EID:

2-s2.0-85051818586

Contributors: Shin, M.; Ware, T.B.; Lee, H.-C.; Hsu, K.-L.
Source: Self-asserted source
Hyeon-Cheol Lee-Okada via Scopus - Elsevier

Autophagy regulates lipid metabolism through selective turnover of NCoR1

2019-12 | Journal article
Part of ISSN: 2041-1723
Source: Self-asserted source
Hyeon-Cheol Lee-Okada

Sensitization of Gastric Cancer Cells to Irinotecan by p53 Activation

BPB Reports
2019-12-27 | Journal article
Source: Self-asserted source
Hyeon-Cheol Lee-Okada

Liver-specific deletion of Ngly1 causes abnormal nuclear morphology and lipid metabolism under food stress

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
2019-11 | Journal article
Part of ISSN: 0925-4439
Source: Self-asserted source
Hyeon-Cheol Lee-Okada

Dietary supplementation of omega-3 fatty acid eicosapentaenoic acid does not ameliorate pruritus in murine models of atopic dermatitis and psoriasis

Journal of Dermatological Science
2019-07 | Journal article
Part of ISSN: 0923-1811
Source: Self-asserted source
Hyeon-Cheol Lee-Okada

The Relationship between TP53 Gene Status and Carboxylesterase 2 Expression in Human Colorectal Cancer

Disease Markers
2018 | Journal article
Contributors: Momoko Ishimine; Hyeon-Cheol Lee; Hirofumi Nakaoka; Hajime Orita; Toshiyuki Kobayashi; Konomi Mizuguchi; Mikumi Endo; Ituro Inoue; Koichi Sato; Takehiko Yokomizo
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Crossref

Dietary omega-3 fatty acids alter the lipid mediator profile and alleviate allergic conjunctivitis without modulating Th2 immune responses

The FASEB Journal
2018-11 | Journal article
Part of ISSN: 0892-6638
Contributors: Toshiaki Hirakata; Hyeon-Cheol Lee; Mai Ohba; Kazuko Saeki; Toshiaki Okuno; Akira Murakami; Akira Matsuda; Takehiko Yokomizo
Source: Self-asserted source
Hyeon-Cheol Lee-Okada via Crossref Metadata Search

Applications of mass spectrometry-based targeted and non-targeted lipidomics

Biochemical and Biophysical Research Communications
2018-10 | Journal article
Contributors: Hyeon-Cheol Lee; Takehiko Yokomizo
Source: check_circle
Crossref

Endurance exercise training and high-fat diet differentially affect composition of diacylglycerol molecular species in rat skeletal muscle

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
2018-02 | Journal article
Part of ISSN: 0363-6119
Contributors: Noriaki Kawanishi; Kana Takagi; Hyeon-Cheol Lee; Daiki Nakano; Toshiaki Okuno; Takehiko Yokomizo; Shuichi Machida
Source: Self-asserted source
Hyeon-Cheol Lee-Okada via Crossref Metadata Search

ABHD4 Regulates Multiple Classes of N-Acyl Phospholipids in the Mammalian Central Nervous System

Source: Self-asserted source
Hyeon-Cheol Lee-Okada

Selective N-Hydroxyhydantoin Carbamate Inhibitors of Mammalian Serine Hydrolases

Source: Self-asserted source
Hyeon-Cheol Lee-Okada

Identification of small subunit of serine palmitoyltransferase a as a lysophosphatidylinositol acyltransferase 1-interacting protein.

Genes to …
2013 | Journal article
Source: Self-asserted source
Hyeon-Cheol Lee-Okada

Depletion of mboa-7, an enzyme that incorporates polyunsaturated fatty acids into phosphatidylinositol (PI), impairs PI 3-phosphate signaling in Caenorhabditis elegans.

Source: Self-asserted source
Hyeon-Cheol Lee-Okada

LPIAT1 regulates arachidonic acid content in phosphatidylinositol and is required for cortical lamination in mice.

2012 | Journal article
Source: Self-asserted source
Hyeon-Cheol Lee-Okada
grade
Preferred source (of 3)‎

Member of the membrane-bound O-acyltransferase (MBOAT) family encodes a lysophospholipid acyltransferase with broad substrate specificity.

Genes to …
2008 | Journal article
Source: Self-asserted source
Hyeon-Cheol Lee-Okada

Caenorhabditis elegans mboa-7, a Member of the MBOAT Family, Is Required for Selective Incorporation of Polyunsaturated Fatty Acids into Phosphatidylinositol

2007 | Journal article
Source: Self-asserted source
Hyeon-Cheol Lee-Okada
grade
Preferred source (of 2)‎

Peer review (15 reviews for 1 publication/grant)

Review activity for Lipids in health and disease (15)