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Employment (5)

GlxAnalytix: Copenhagen, DK

2022-08 to present | Senior Glycobiologist
Employment
Source: Self-asserted source
Christoffer Goth

University of Copenhagen: Copenhagen, DK

2019 to 2022-08 | Post doc (Biomedical Sciences)
Employment
Source: Self-asserted source
Christoffer Goth

Harvard Medical School: Boston, MA, US

2017 to 2019 | Post doc (National Center for Functional Glycomics)
Employment
Source: Self-asserted source
Christoffer Goth

University of Copenhagen: Copenhagen, DK

2016 to 2017 | Post doc
Employment
Source: Self-asserted source
Christoffer Goth

University of Copenhagen: Copenhagen, DK

2013 to 2016 | PhD student (Copenhagen Center for Glycomics)
Employment
Source: Self-asserted source
Christoffer Goth

Education and qualifications (1)

University of Copenhagen: Copenhagen, DK

2013-04-01 to 2016-07-01 | PhD (Institute for Cellular and Molecular Medicine)
Education
Source: Self-asserted source
Christoffer Goth

Funding (2)

Glyco-sulfo Barcodes of Chemokine Binding

2019-06 to 2022-06 | Grant
Lundbeckfonden (Copenhagen, DK)
Source: Self-asserted source
Christoffer Goth

GPCRs are Fine-Tuned by O-Glycosylation - A Cell-Based Screening Platform

2017-01-01 to 2017-12-31 | Grant
Danish Agency for Science and Higher Education (Copenhagen, DK)
URL: https://app.dimensions.ai/details/grant/grant.7148284
GRANT_NUMBER: 6e2ae3911c9074154eb81d6ffecbaf81
Source: Self-asserted source
Christoffer Goth via DimensionsWizard

Works (18)

Selective Boosting of CCR7-Acting Chemokines; Short Peptides Boost Chemokines with Short Basic Tails, Longer Peptides Boost Chemokines with Long Basic Tails

International Journal of Molecular Sciences
2022-01-26 | Journal article
DOI: 10.3390/ijms23031397
Contributors: Emma Probst Brandum; Astrid Sissel Jørgensen; Marina Barrio Calvo; Katja Spiess; Francis C. Peterson; Zhang Yang; Brian F. Volkman; Christopher T. Veldkamp; Mette Marie Rosenkilde; Christoffer Knak Goth et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Novel lamprey antibody recognizes terminal sulfated galactose epitopes on mammalian glycoproteins

Communications Biology
2021-06-03 | Journal article
DOI: 10.1038/s42003-021-02199-7
Contributors: Tanya R. McKitrick; Steffen M. Bernard; Alexander J. Noll; Bernard C. Collins; Christoffer K. Goth; Alyssa M. McQuillan; Jamie Heimburg-Molinaro; Brantley R. Herrin; Ian A. Wilson; Max D. Cooper et al.
Source: check_circle
Crossref

Emerging patterns of tyrosine sulfation and O-glycosylation cross-talk and co-localization

Current Opinion in Structural Biology
2020-06 | Journal article
DOI: 10.1016/j.sbi.2019.12.002
Contributors: Akul Y Mehta; Jamie Heimburg-Molinaro; Richard D Cummings; Christoffer K Goth
Source: check_circle
Crossref

Parallel Glyco-SPOT Synthesis of Glycopeptide Libraries.

Cell chemical biology
2020-06-29 | Journal article
DOI: 10.1016/j.chembiol.2020.06.007
PMID: 32610041
Source: Self-asserted source
Christoffer Goth

G Protein-Coupled Receptors in the Sweet Spot: Glycosylation and other Post-translational Modifications

ACS Pharmacology & Translational Science
2020-04-10 | Journal article
DOI: 10.1021/acsptsci.0c00016
Contributors: Christoffer K. Goth; Ulla E. Petäjä-Repo; Mette M. Rosenkilde
Source: check_circle
Crossref

Development of smart anti-glycan reagents using immunized lampreys

Communications Biology
2020-02-28 | Journal article
DOI: 10.1038/s42003-020-0819-2
Contributors: Tanya R. McKitrick; Christoffer K. Goth; Charles S. Rosenberg; Hirotomo Nakahara; Jamie Heimburg-Molinaro; Alyssa M. McQuillan; Rosalia Falco; Nicholas J. Rivers; Brantley R. Herrin; Max D. Cooper et al.
Source: check_circle
Crossref

Discovery of O-glycans on atrial natriuretic peptide (ANP) that affect both its proteolytic degradation and potency at its cognate receptor

Journal of Biological Chemistry
2019-08 | Journal article
DOI: 10.1074/jbc.RA119.008102
Contributors: Lasse H. Hansen; Thomas Daugbjerg Madsen; Christoffer K. Goth; Henrik Clausen; Yang Chen; Nina Dzhoyashvili; Seethalakshmi R. Iyer; S. Jeson Sangaralingham; John C. Burnett, Jr.; Jens F. Rehfeld et al.
Source: check_circle
Crossref

A validated collection of mouse monoclonal antibodies to human glycosyltransferases functioning in mucin-type O-glycosylation.

Glycobiology
2019-08-01 | Journal article
DOI: 10.1093/glycob/cwz041
PMID: 31172184
PMC: PMC6704369
Source: Self-asserted source
Christoffer Goth

Probing the contribution of individual polypeptide GalNAc-transferase isoforms to the O-glycoproteome by inducible expression in isogenic cell lines.

The Journal of biological chemistry
2018-10 | Journal article
DOI: 10.1074/jbc.ra118.004516
PMID: 30327431
Contributors: Hintze J; Ye Z; Narimatsu Y; Madsen TD; Joshi HJ; Goth CK; Linstedt A; Bachert C; Mandel U; Bennett EP et al.
Source: Self-asserted source
Christoffer Goth via Europe PubMed Central

Fine-Tuning Limited Proteolysis: A Major Role for Regulated Site-Specific O-Glycosylation.

Trends in biochemical sciences
2018-03 | Journal article
DOI: 10.1016/j.tibs.2018.02.005
PMID: 29506880
Contributors: Goth CK; Vakhrushev SY; Joshi HJ; Clausen H; Schjoldager KT
Source: Self-asserted source
Christoffer Goth via Europe PubMed Central

Site-specific O-glycosylation of members of the low-density lipoprotein receptor superfamily enhances ligand interactions.

The Journal of biological chemistry
2018-03 | Journal article
DOI: 10.1074/jbc.m117.817981
PMID: 29559555
Contributors: Wang S; Mao Y; Narimatsu Y; Ye Z; Tian W; Goth CK; Lira-Navarrete E; Pedersen NB; Benito-Vicente A; Martin C et al.
Source: Self-asserted source
Christoffer Goth via Europe PubMed Central

TAILS N-terminomics and proteomics reveal complex regulation of proteolytic cleavage by O-glycosylation.

The Journal of biological chemistry
2018-03 | Journal article
DOI: 10.1074/jbc.ra118.001978
PMID: 29593093
Contributors: King SL; Goth CK; Eckhard U; Joshi HJ; Haue AD; Vakhrushev SY; Schjoldager KT; Overall CM; Wandall HH
Source: Self-asserted source
Christoffer Goth via Europe PubMed Central

Site-specific O-glycosylation of N-terminal serine residues by polypeptide GalNAc-transferase 2 modulates human δ-opioid receptor turnover at the plasma membrane.

Cellular signalling
2017-10 | Journal article
DOI: 10.1016/j.cellsig.2017.10.016
PMID: 29097258
Contributors: Lackman JJ; Goth CK; Halim A; Vakhrushev SY; Clausen H; Petäjä-Repo UE
Source: Self-asserted source
Christoffer Goth via Europe PubMed Central

Site-specific O-Glycosylation by Polypeptide N-Acetylgalactosaminyltransferase 2 (GalNAc-transferase T2) Co-regulates β1-Adrenergic Receptor N-terminal Cleavage.

The Journal of biological chemistry
2017-02 | Journal article
DOI: 10.1074/jbc.M116.730614
PMID: 28167537
PMC: PMC5377785
Contributors: Goth CK; Tuhkanen HE; Khan H; Lackman JJ; Wang S; Narimatsu Y; Hansen LH; Overall CM; Clausen H; Schjoldager KT et al.
Source: Self-asserted source
Christoffer Goth via Europe PubMed Central

A systematic study of modulation of ADAM-mediated ectodomain shedding by site-specific O-glycosylation.

Proceedings of the National Academy of Sciences of the United States of America
2015-11 | Journal article
DOI: 10.1073/pnas.1511175112
PMID: 26554003
PMC: PMC4664366
Contributors: Goth CK; Halim A; Khetarpal SA; Rader DJ; Clausen H; Schjoldager KT
Source: Self-asserted source
Christoffer Goth via Europe PubMed Central

Deconstruction of O-glycosylation--GalNAc-T isoforms direct distinct subsets of the O-glycoproteome.

EMBO reports
2015-11 | Journal article
DOI: 10.15252/embr.201540796
PMID: 26566661
PMC: PMC4693523
Contributors: Schjoldager KT; Joshi HJ; Kong Y; Goth CK; King SL; Wandall HH; Bennett EP; Vakhrushev SY; Clausen H
Source: Self-asserted source
Christoffer Goth via Europe PubMed Central

The heterotaxy gene GALNT11 glycosylates Notch to orchestrate cilia type and laterality.

Nature
2013-11 | Journal article
DOI: 10.1038/nature12723
PMID: 24226769
PMC: PMC3869867
Contributors: Boskovski MT; Yuan S; Pedersen NB; Goth CK; Makova S; Clausen H; Brueckner M; Khokha MK
Source: Self-asserted source
Christoffer Goth via Europe PubMed Central

A systematic study of site-specific GalNAc-type O-glycosylation modulating proprotein convertase processing.

The Journal of biological chemistry
2011-09 | Journal article
DOI: 10.1074/jbc.M111.287912
PMID: 21937429
PMC: PMC3220544
Contributors: Schjoldager KT; Vester-Christensen MB; Goth CK; Petersen TN; Brunak S; Bennett EP; Levery SB; Clausen H
Source: Self-asserted source
Christoffer Goth via Europe PubMed Central
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