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Employment (1)

University of Milano-Bicocca: Milan, IT

2024-07-01 to 2025-12-31 | Post-PhD Fellowship (School of Medicine and Surgery)
Employment
Source: Self-asserted source
Francesco Pettini

Education and qualifications (2)

Università degli Studi di Milano: Milano, IT

2023-03-15 to 2024-03-15 | 2nd level vocational master
Qualification
Source: Self-asserted source
Francesco Pettini

University of Siena: Siena, Toscana, IT

2019-10-01 to 2023-03-27 | Doctor of Philosophy (Department of Medical Biotechnologies)
Education
Source: Self-asserted source
Francesco Pettini

Funding (1)

Effect of the state of potassium channels on drug binding

2021-11 to 2022-02 | Salary award
University of Edinburgh and EPSRC (EP/P020267/1) (Edinburgh, Scotland, GB)
URL: https://hpc-europa.cineca.it/
GRANT_NUMBER:

HPC17N4H8A
Source: Self-asserted source
Francesco Pettini

Works (13)

Electrophysiology, molecular modelling, and functional analysis of the effects of dietary quercetin and flavonoid analogues on Kir6.1 channels in rat stomach fundus smooth muscle

Biochemical Pharmacology
2023-12 | Journal article
DOI: 10.1016/j.bcp.2023.115969
Part of ISSN: 0006-2952
Contributors: Francesco Pettini; Ottavia Spiga; Simone Furini; FABIO FUSI
Source: Self-asserted source
Francesco Pettini

<i>HLA‐DPB1*013:01</i> associates with enhanced, and <i>KIR2DS4*001</i> with diminished protection from developing severe <scp>COVID</scp>‐19

HLA
2023-10-18 | Journal article
DOI: 10.1111/tan.15251
Part of ISSN: 2059-2302
Part of ISSN: 2059-2310
Contributors: Farias, TDJ; Silvia Brugiapaglia; Susanna Croci; Paola Magistroni; Claudia Curcio; Kristina Zguro; Chiara Fallerini; Francesca Fava; Francesco Pettini; Katherine M. Kichula et al.
Source: Self-asserted source
Francesco Pettini

Computational Methods to unveil the Structural Bases for the recognition of SARS-CoV-2 by Human Nicotinic Acetylcholine Receptors

International Journal Of Pharmaceutical And Bio-Medical Science
2023-03-15 | Journal article
DOI: 10.47191/ijpbms/v3-i3-05
Part of ISSN: 2767-827X
Part of ISSN: 2767-830X
Contributors: Ottavia Spiga; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Via A. Moro 2, 53100 Siena, Italy; Luisa Frusciante; Michela Geminiani; Francesco Pettini; Alfonso Trezza; Anna Visibelli; Annalisa Santucci; & SienabioACTIVE - SbA, 53100 Siena, Italy Competence Center ARTES 4.0, Siena, Italy & Competence Center ARTES 4.0, 53100 Siena, Italy; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Via A. Moro 2, 53100 Siena, Italy et al.
Source: Self-asserted source
Francesco Pettini

Molecular Dynamics simulation of the hERG channel assisting Precision Medicine in Channelopathies

2023-03-06 | Dissertation or Thesis
DOI: 10.25434/FRANCESCO-PETTINI_PHD2023
Contributors: Francesco Pettini
Source: Self-asserted source
Francesco Pettini

Early Steps in C-Type Inactivation of the hERG Potassium Channel

Journal of Chemical Information and Modeling
2023-01-09 | Journal article
DOI: 10.1021/acs.jcim.2c01028
Contributors: Francesco Pettini; Carmen Domene; Simone Furini
Source: check_circle
Crossref

Bioinformatics Approaches to Predict Mutation Effects in the Binding Site of the Proangiogenic Molecule CD93

Frontiers in Bioinformatics
2022-06-21 | Journal article
DOI: 10.3389/fbinf.2022.891553
Part of ISSN: 2673-7647
Source: Self-asserted source
Francesco Pettini

Proton pump inhibitors directly block herg-potassium channel and independently increase the risk of QTc prolongation in a large cohort of US veterans

Circulation: Arrhythmia and Electrophysiology
2021 | Journal article
DOI: 10.1161/CIRCEP.121.010042
EID:

2-s2.0-85111160467

Part of ISSN: 19413084 19413149
Contributors: Lazzerini, P.E.; Cartocci, A.; Qu, Y.S.; Saponara, S.; Furini, S.; Fusi, F.; Fabris, F.; Gamberucci, A.; El-Sherif, N.; Cevenini, G. et al.
Source: Self-asserted source
Francesco Pettini via Scopus - Elsevier

Multi-Omics Model Applied to Cancer Genetics

International Journal of Molecular Sciences
2021-05-27 | Journal article
DOI: 10.3390/ijms22115751
Contributors: Francesco Pettini; Anna Visibelli; Vittoria Cicaloni; Daniele Iovinelli; Ottavia Spiga
Source: check_circle
Crossref
grade
Preferred source (of 3)‎

Machine learning application for patient stratification and phenotype/genotype investigation in a rare disease.

Briefings in bioinformatics
2021-02 | Journal article
DOI: 10.1093/bib/bbaa434
PMID: 33538294
Contributors: Spiga O; Cicaloni V; Dimitri GM; Pettini F; Braconi D; Bernini A; Santucci A
Source: Self-asserted source
Francesco Pettini via Europe PubMed Central

Potential roles of protease inhibitors in anticancer therapy

Cancer-Leading Proteases: Structures, Functions, and Inhibition
2020 | Book chapter
Part of DOI: 10.1016/B978-0-12-818168-3.00002-4
EID:

2-s2.0-85086174627
Contributors: Trezza, A.; Cicaloni, V.; Pettini, F.; Spiga, O.
Source: Self-asserted source
Francesco Pettini via Scopus - Elsevier

Applications of in silico methods for design and development of drugs targeting protein-protein interactions

Current Topics in Medicinal Chemistry
2019 | Journal article
DOI: 10.2174/1568026619666190304153901
EID:

2-s2.0-85068422465

Part of ISSN: 18734294 15680266
Contributors: Cicaloni, V.; Trezza, A.; Pettini, F.; Spiga, O.
Source: Self-asserted source
Francesco Pettini via Scopus - Elsevier

Structural investigation of Rett-inducing MeCP2 mutations

Genes and Diseases
2019 | Journal article
DOI: 10.1016/j.gendis.2018.09.005
EID:

2-s2.0-85055425069

Part of ISSN: 23523042
Contributors: Spiga, O.; Gardini, S.; Rossi, N.; Cicaloni, V.; Pettini, F.; Niccolai, N.; Santucci, A.
Source: Self-asserted source
Francesco Pettini via Scopus - Elsevier

A focus on ebola virus polymerase: Structure, functions and antiviral therapies

Viral Polymerases: Structures, Functions and Roles as Antiviral Drug Targets
2018 | Book chapter
Part of DOI: 10.1016/B978-0-12-815422-9.00007-3
EID:

2-s2.0-85082605624
Contributors: Pettini, F.; Trezza, A.; Spiga, O.
Source: Self-asserted source
Francesco Pettini via Scopus - Elsevier
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