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Works (3)

Aire mediates tolerance to insulin through thymic trimming of high-affinity T cell clones

Proceedings of the National Academy of Sciences
2024-05-14 | Journal article
DOI: 10.1073/pnas.2320268121
Contributors: Jennifer A. Smith; Benjamin T. K. Yuen; Whitney Purtha; Jared M. Balolong; Jonah D. Phipps; Frances Crawford; Jeffrey A. Bluestone; John W. Kappler; Mark S. Anderson
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Structures suggest an approach for converting weak self-peptide tumor antigens into superagonists for CD8 T cells in cancer

Proceedings of the National Academy of Sciences
2021-06-08 | Journal article
DOI: 10.1073/pnas.2100588118
Contributors: Pengcheng Wei; Kimberly R. Jordan; Jonathan D. Buhrman; Jun Lei; Hexiang Deng; Philippa Marrack; Shaodong Dai; John W. Kappler; Jill E. Slansky; Lei Yin
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Lysosomal cathepsin creates chimeric epitopes for diabetogenic CD4 T cells via transpeptidation

Journal of Experimental Medicine
2021-02-01 | Journal article
DOI: 10.1084/jem.20192135
Contributors: Brendan Reed; Frances Crawford; Ryan C. Hill; Niyun Jin; Janice White; S. Harsha Krovi; Philippa Marrack; Kirk Hansen; John W. Kappler
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