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Novel brain-penetrant inhibitor of G9a methylase blocks Alzheimer’s disease proteopathology for precision medication

2023-11-21 | Preprint
DOI: 10.21203/rs.3.rs-2743792/v1
Contributors: Xian Chen; Ling Xie; Ryan Sheehy; Yan Xiong; Adil Muneer; John Wrobel; Kwang-Su Park; Jing Liu; Julia Velez; Yanjia Luo et al.
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IL-11 induces NLRP3 inflammasome activation in monocytes and inflammatory cell migration to the central nervous system

Proceedings of the National Academy of Sciences
2023-06-27 | Journal article
DOI: 10.1073/pnas.2221007120
Contributors: Maryamsadat Seyedsadr; Yan Wang; Manal Elzoheiry; Sowmya Shree Gopal; Soohwa Jang; Gayel Duran; Inna Chervoneva; Ezgi Kasimoglou; John A. Wrobel; Daniel Hwang et al.
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STING-induced regulatory B cells compromise NK function in cancer immunity

Nature
2022-10-13 | Journal article
DOI: 10.1038/s41586-022-05254-3
Contributors: Sirui Li; Bhalchandra Mirlekar; Brandon M. Johnson; W. June Brickey; John A. Wrobel; Na Yang; Dingka Song; Sarah Entwistle; Xianming Tan; Meng Deng et al.
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Protocol for proteogenomic dissection of intronic splicing enhancer interactome for prediction of individualized cancer prognosis

STAR Protocols
2021-03 | Journal article
DOI: 10.1016/j.xpro.2021.100338
Contributors: Li Wang; John A. Wrobel; Ling Xie; Xian Chen
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