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Dawei Zhang

Other IDs

Loop profile: 752938
Loop profile: 905186
SciProfiles: 953852

Keywords

Metabolic engineering, Protein expression system, protein secertion pathway, sec pathway

Countries

China

Activities

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Employment (1)

Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences: ??, CN

Employment
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iAuthor

Education and qualifications (3)

California Institute of Technology: Pasadena, CA, US

2008 to 2012 | Postdoc
Education
Source: Self-asserted source
Dawei Zhang

University of Wisconsin Milwaukee: Milwaukee, WI, US

2007-07 to 2008-07 | Postdoc
Education
Source: Self-asserted source
Dawei Zhang

Beijing University of Chemical Technology: Beijing, Beijing, CN

2004 to 2007-06 | PhD
Education
Source: Self-asserted source
Dawei Zhang

Works (37)

Pathway and protein channel engineering of Bacillus subtilis for improved production of desthiobiotin and biotin

Synthetic and Systems Biotechnology
2025 | Journal article
DOI: 10.1016/j.synbio.2024.11.005
Contributors: Yue Wu; Guang-Qing Du; Dong-Han Ma; Jin-Long Li; Huan Fang; Hui-Na Dong; Zhao-Xia Jin; Da-Wei Zhang
Source: check_circle
Crossref

Monitoring and dynamically controlling glucose uptake rate and central metabolism

Nature Chemical Engineering
2025-01-17 | Journal article
DOI: 10.1038/s44286-024-00163-w
Contributors: Dongqin Ding; Yaru Zhu; Danyang Bai; Tongxin Wan; Sang Yup Lee; Dawei Zhang
Source: check_circle
Crossref

Increasing Vitamin K2 Synthesis in Bacillus subtilis by Controlling the Expression of MenD and Stabilizing MenA

Journal of Agricultural and Food Chemistry
2024-10-07 | Journal article
DOI: 10.1021/acs.jafc.4c07385
Contributors: Wei Huang; Jinlong Li; Qiyao Zhu; Jianan Lv; Rui Zhu; Chunxiang Pu; Huabing Zhao; Gang Fu; Dawei Zhang
Source: check_circle
Crossref

A hybrid RNA-protein biosensor for high-throughput screening of adenosylcobalamin biosynthesis

Synthetic and Systems Biotechnology
2024-09 | Journal article
DOI: 10.1016/j.synbio.2024.04.008
Contributors: Xia Yang; Huiying Wang; Dongqin Ding; Huan Fang; Huina Dong; Dawei Zhang
Source: check_circle
Crossref

Multivariate modular metabolic engineering and medium optimization for vitamin B12 production by Escherichia coli

Synthetic and Systems Biotechnology
2024-09 | Journal article
DOI: 10.1016/j.synbio.2024.03.017
Contributors: Feitao Chen; Huan Fang; Jianghua Zhao; Pingtao Jiang; Huina Dong; Ying Zhao; Huiying Wang; Tongcun Zhang; Dawei Zhang
Source: check_circle
Crossref

Highly flexible cell membranes are the key to efficient production of lipophilic compounds

Journal of Lipid Research
2024-08 | Journal article
DOI: 10.1016/j.jlr.2024.100597
Contributors: Qiyao Zhu; Sijia Wang; Gang Fu; Fengming Guo; Wei Huang; Tengyue Zhang; Huina Dong; Zhaoxia Jin; Dawei Zhang
Source: check_circle
Crossref

Engineering and finetuning expression of SerC for balanced metabolic flux in vitamin B6 production

Synthetic and Systems Biotechnology
2024-06 | Journal article
DOI: 10.1016/j.synbio.2024.03.005
Contributors: Kai Chen; Linxia Liu; Jinlong Li; Zhizhong Tian; Hongxing Jin; Dawei Zhang
Source: check_circle
Crossref

Multiple Cofactor Engineering Strategies to Enhance Pyridoxine Production in Escherichia coli

Microorganisms
2024-05-03 | Journal article
DOI: 10.3390/microorganisms12050933
Contributors: Lijuan Wu; Jinlong Li; Yahui Zhang; Zhizhong Tian; Zhaoxia Jin; Linxia Liu; Dawei Zhang
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Standardized Iterative Genome Editing Method for Escherichia coli Based on CRISPR-Cas9

ACS Synthetic Biology
2024-02-16 | Journal article
DOI: 10.1021/acssynbio.3c00585
Contributors: Huan Fang; Jianghua Zhao; Xinfang Zhao; Ning Dong; Ying Zhao; Dawei Zhang
Source: check_circle
Crossref

A synthetic cell-free 36-enzyme reaction system for vitamin B12 production

Nature Communications
2023-08-24 | Journal article
DOI: 10.1038/s41467-023-40932-4
Contributors: Qian Kang; Huan Fang; Mengjie Xiang; Kaixing Xiao; Pingtao Jiang; Chun You; Sang Yup Lee; Dawei Zhang
Source: check_circle
Crossref

Optimization of Hydrogenobyrinic Acid Synthesis in a Cell-Free Multienzyme Reaction by Novel S-Adenosyl-methionine Regeneration

ACS Synthetic Biology
2023-04-21 | Journal article
DOI: 10.1021/acssynbio.3c00109
Contributors: Kaixing Xiao; Qian Kang; Mengjie Xiang; Dachun Gong; Huan Fang; Xuan Tu; Dawei Zhang
Source: check_circle
Crossref

Characterization of a Riboflavin-Producing Mutant of Bacillus subtilis Isolated by Droplet-Based Microfluidics Screening

Microorganisms
2023-04-20 | Journal article
DOI: 10.3390/microorganisms11041070
Contributors: Fan Xu; Chuan Liu; Miaomiao Xia; Shixin Li; Ran Tu; Sijia Wang; Hongxing Jin; Dawei Zhang
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

An Efficient CRISPR/Cas12e System for Genome Editing in Sinorhizobium meliloti

ACS Synthetic Biology
2023-03-17 | Journal article
DOI: 10.1021/acssynbio.2c00629
Contributors: Guangqing Liu; Huiying Wang; Baisong Tong; Yali Cui; Sibylle C. Vonesch; Huina Dong; Dawei Zhang
Source: check_circle
Crossref

A versatile Cas12k-based genetic engineering toolkit (C12KGET) for metabolic engineering in genetic manipulation-deprived strains

Nucleic Acids Research
2022-08-26 | Journal article
DOI: 10.1093/nar/gkac655
Contributors: Yali Cui; Huina Dong; Baisong Tong; Huiying Wang; Xipeng Chen; Guangqing Liu; Dawei Zhang
Source: check_circle
Crossref

Assessment of Spoilage Microbiota of Rainbow Trout (Oncorhynchus mykiss) during Storage by 16S rDNA Sequencing

Journal of Food Quality
2022-03-30 | Journal article
DOI: 10.1155/2022/5367984
Contributors: Guangqing Du; Yuanming Gai; Hui Zhou; Shaoping Fu; Dawei Zhang; Shudong He
Source: check_circle
Crossref

An operator-based expression toolkit for Bacillus subtilis enables fine-tuning of gene expression and biosynthetic pathway regulation

Proceedings of the National Academy of Sciences
2022-03-15 | Journal article
DOI: 10.1073/pnas.2119980119
Contributors: Gang Fu; Jie Yue; Dandan Li; Yixin Li; Sang Yup Lee; Dawei Zhang
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Crossref

Identification of a xylose‐inducible promoter and its application for improving vitamin B12 production in Sinorhizobium meliloti

Biotechnology and Applied Biochemistry
2021-08 | Journal article
DOI: 10.1002/bab.2002
Contributors: Zhenquan Liu; Huina Dong; Xiangying Wu; Huan Fang; Lina Cong; Beiwei Zhu; Dawei Zhang
Source: check_circle
Crossref

Analyzing the genetic characteristics of a tryptophan-overproducing Escherichia coli

Bioprocess and Biosystems Engineering
2021-08-22 | Journal article
DOI: 10.1007/s00449-021-02552-4
Contributors: Dongqin Ding; Danyang Bai; Jinlong Li; Zhitao Mao; Yaru Zhu; Pi Liu; Jianping Lin; Hongwu Ma; Dawei Zhang
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Crossref

Metabolic profiling analysis of the vitamin B12 producer Propionibacterium freudenreichii

MicrobiologyOpen
2021-06 | Journal article
DOI: 10.1002/mbo3.1199
Contributors: Jiao Liu; Yongfei Liu; Jie Wu; Huan Fang; Zhaoxia Jin; Dawei Zhang
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Crossref

Establishment of a Biosensor-based High-Throughput Screening Platform for Tryptophan Overproduction

ACS Synthetic Biology
2021-06-18 | Journal article
DOI: 10.1021/acssynbio.0c00647
Contributors: Yongfei Liu; Huiling Yuan; Dongqin Ding; Huina Dong; Qinhong Wang; Dawei Zhang
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Crossref

Signal Recognition Particle Suppressor Screening Reveals the Regulation of Membrane Protein Targeting by the Translation Rate

mBio
2021-02-23 | Journal article
DOI: 10.1128/mBio.02373-20
Contributors: Liuqun Zhao; Yanyan Cui; Gang Fu; Zixiang Xu; Xiaoping Liao; Dawei Zhang; Paul Dunman
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Crossref

Compensating complete loss of signal recognition particle during co-translational protein targeting by the translation speed and accuracy

2021-01-07 | Preprint
DOI: 10.1101/2021.01.06.425660
Contributors: Liuqun Zhao; Gang Fu; Yanyan Cui; Zixiang Xu; Tao Cai; Dawei Zhang
Source: check_circle
Crossref

Advances on systems metabolic engineering of Bacillus subtilis as a chassis cell

Synthetic and Systems Biotechnology
2020-12 | Journal article
DOI: 10.1016/j.synbio.2020.07.005
Contributors: Mengjie Xiang; Qian Kang; Dawei Zhang
Source: check_circle
Crossref

Expanding application of CRISPR-Cas9 system in microorganisms

Synthetic and Systems Biotechnology
2020-12 | Journal article
DOI: 10.1016/j.synbio.2020.08.001
Contributors: Jing Zhao; Huan Fang; Dawei Zhang
Source: check_circle
Crossref

A multistrategy approach for improving the expression of E. coli phytase in Pichia pastoris

Journal of Industrial Microbiology & Biotechnology
2020-12-15 | Journal article
DOI: 10.1007/s10295-020-02311-6
Contributors: Yuankun Helian; Yuanming Gai; Huan Fang; Yumei Sun; Dawei Zhang
Source: check_circle
Crossref

Manipulation of Purine Metabolic Networks for Riboflavin Production in Bacillus subtilis

ACS Omega
2020-11-17 | Journal article
DOI: 10.1021/acsomega.0c03867
Contributors: Yiwen Sun; Chuan Liu; Wenzhu Tang; Dawei Zhang
Source: check_circle
Crossref

Engineering Escherichia coli to improve tryptophan production via genetic manipulation of precursor and cofactor pathways

Synthetic and Systems Biotechnology
2020-09 | Journal article
DOI: 10.1016/j.synbio.2020.06.009
Contributors: Zhu Li; Dongqin Ding; Huiying Wang; Linxia Liu; Huan Fang; Tao Chen; Dawei Zhang
Source: check_circle
Crossref

Enhanced production of d‐psicose 3‐epimerase in Bacillus subtilis by regulation of segmented fermentation

Biotechnology and Applied Biochemistry
2020-09 | Journal article
DOI: 10.1002/bab.1831
Contributors: Gang Fu; Shibin Zhang; Huina Dong; Jingqi Chen; Ran Tu; Dawei Zhang
Source: check_circle
Crossref

Metabolic engineering of Escherichia coli for production of chemicals derived from the shikimate pathway

Journal of Industrial Microbiology & Biotechnology
2020-07-08 | Journal article
DOI: 10.1007/s10295-020-02288-2
Contributors: Zhu Li; Huiying Wang; Dongqin Ding; Yongfei Liu; Huan Fang; Zhishuai Chang; Tao Chen; Dawei Zhang
Source: check_circle
Crossref

Principle and potential applications of the non-classical protein secretory pathway in bacteria

Applied Microbiology and Biotechnology
2020-02-18 | Journal article
DOI: 10.1007/s00253-019-10285-4
Contributors: Qian Kang; Dawei Zhang
Source: check_circle
Crossref

Hyper-secretion mechanism exploration of a heterologous creatinase in Bacillus subtilis

Biochemical Engineering Journal
2020-01 | Journal article
DOI: 10.1016/j.bej.2019.107419
Contributors: Zhengyu Tao; Gang Fu; Sijia Wang; Zhaoxia Jin; Jianping Wen; Dawei Zhang
Source: check_circle
Crossref

Strategies for Applying Nonhomologous End Joining-Mediated Genome Editing in Prokaryotes

ACS Synthetic Biology
2019-10-18 | Journal article
DOI: 10.1021/acssynbio.9b00179
Contributors: Yali Cui; Huina Dong; Yuanyuan Ma; Dawei Zhang
Source: check_circle
Crossref

Property Improvement of α-Amylase from Bacillus stearothermophilus by Deletion of Amino Acid Residues Arginine 179-Glycine 180

Food Technology and Biotechnology
2018 | Journal article
DOI: 10.17113/ftb.56.01.18.5448
Contributors: Yuanming Gai; Jingqi Chen; Shibin Zhang; Beiwei Zhu; Dawei Zhang
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Crossref

Systematic Screening of Optimal Signal Peptides for Secretory Production of Heterologous Proteins in Bacillus subtilis

Journal of Agricultural and Food Chemistry
2018-12-19 | Journal article
DOI: 10.1021/acs.jafc.8b04183
Contributors: Gang Fu; Jinlan Liu; Jinshan Li; Beiwei Zhu; Dawei Zhang
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Crossref

Metabolic engineering of Escherichia coli for de novo biosynthesis of vitamin B12

Nature Communications
2018-11-21 | Journal article
DOI: 10.1038/s41467-018-07412-6
Contributors: Huan Fang; Dong Li; Jie Kang; Pingtao Jiang; Jibin Sun; Dawei Zhang
Source: check_circle
Crossref

Biosensor-Based Evolution and Elucidation of a Biosynthetic Pathway in Escherichia coli

ACS Synthetic Biology
2017-05-19 | Journal article
DOI: 10.1021/acssynbio.6b00328
Contributors: Yongfei Liu; Yinyin Zhuang; Dongqin Ding; Yiran Xu; Jibin Sun; Dawei Zhang
Source: check_circle
Crossref

High-Efficiency Secretion of β-Mannanase in Bacillus subtilis through Protein Synthesis and Secretion Optimization

Journal of Agricultural and Food Chemistry
2017-03-29 | Journal article
DOI: 10.1021/acs.jafc.6b05528
Contributors: Yafeng Song; Gang Fu; Huina Dong; Jianjun Li; Yuguang Du; Dawei Zhang
Source: check_circle
Crossref

Peer review (19 reviews for 7 publications/grants)

Review activity for ACS sustainable chemistry & engineering. (3)
Review activity for ACS synthetic biology. (2)
Review activity for Applied biochemistry and biotechnology. (2)
Review activity for Applied microbiology and biotechnology (3)
Review activity for Journal of agricultural and food chemistry. (3)
Review activity for Journal of microbiology. (1)
Review activity for Nature communications (5)
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