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MYB insufficiency disrupts proteostasis in hematopoietic stem cells, leading to age-related neoplasia

Blood
2023-04-13 | Journal article
Contributors: Mary L. Clarke; Roza B. Lemma; David S. Walton; Giacomo Volpe; Boris Noyvert; Odd S. Gabrielsen; Jon Frampton
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Pioneer transcription factors are associated with the modulation of DNA methylation patterns across cancers

Epigenetics & Chromatin
2022-12 | Journal article
Contributors: Roza Berhanu Lemma; Thomas Fleischer; Emily Martinsen; Marit Ledsaak; Vessela Kristensen; Ragnhild Eskeland; Odd Stokke Gabrielsen; Anthony Mathelier
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Pioneer transcription factors are associated with the modulation of DNA methylation patterns across cancers

2021-05-10 | Other
Contributors: Roza Berhanu Lemma; Thomas Fleischer; Emily Martinsen; Marit Ledsaak; Vessela Kristensen; Ragnhild Eskeland; Odd Stokke Gabrielsen; Anthony Mathelier
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Dissecting the transactivation domain (tAD) of the transcription factor c‐Myb to assess recent models of tAD function

FEBS Open Bio
2020-11 | Journal article
Contributors: Guro Næs; Jan Ove Storesund; Priyanga‐Dina Udayakumar; Marit Ledsaak; Odd Stokke Gabrielsen
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Open the LID: LXRα regulates ChREBPα transactivity in a target gene-specific manner through an agonist-modulated LBD-LID interaction

2019-12-20 | Preprint
Contributors: Qiong Fan; Rikke C. Nørgaard; Ivar Grytten; Cecilie M. Ness; Christin Lucas; Kristin Vekterud; Helen Soedling; Jason Matthews; Roza B. Lemma; Odd S. Gabrielsen et al.
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The pioneer factor activity of c-Myb involves recruitment of p300 and induction of histone acetylation followed by acetylation-induced chromatin dissociation

Epigenetics & Chromatin
2018-12 | Journal article
Contributors: Bettina M. Fuglerud; Marit Ledsaak; Marie Rogne; Ragnhild Eskeland; Odd S. Gabrielsen
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A c-Myb mutant causes deregulated differentiation due to impaired histone binding and abrogated pioneer factor function

Nucleic Acids Research
2017-07-27 | Journal article
Contributors: Bettina M. Fuglerud; Roza B. Lemma; Pimthanya Wanichawan; Arvind Y. M. Sundaram; Ragnhild Eskeland; Odd S. Gabrielsen
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