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Sungkyunkwan University - Natural Sciences Campus: Suwon, Gyeonggi-do, KR

2020-03-01 to present | Assistant Professor (Integrative Biotechnology)
Employment
Source: Self-asserted source
Young-Jun Jeon

Education and qualifications (4)

The Ohio State University: Columbus, OH, US

Doctorate Degree (MCDB Program, School of Medicine)
Education
Source: Self-asserted source
Young-Jun Jeon

Sungkyunkwan University - Natural Sciences Campus: Suwon, Gyeonggi-do, KR

Bachelor of Science (Genetic Engineering)
Education
Source: Self-asserted source
Young-Jun Jeon

Stanford University School of Medicine: Stanford, CA, US

Postdoctoral Researcher (Stanford Cancer Institute)
Qualification
Source: Self-asserted source
Young-Jun Jeon

Gwangju Institute of Science and Technology: Gwangju, KR

Master's degree (Life Science)
Education
Source: Self-asserted source
Young-Jun Jeon

Works (40)

Data from <i>KEAP1/NFE2L2</i> Mutations Predict Lung Cancer Radiation Resistance That Can Be Targeted by Glutaminase Inhibition

2023-04-03 | Preprint
DOI: 10.1158/2159-8290.c.6547724
Contributors: Michael S. Binkley; Young-Jun Jeon; Monica Nesselbush; Everett J. Moding; Barzin Y. Nabet; Diego Almanza; Christian Kunder; Henning Stehr; Christopher H. Yoo; Siyeon Rhee et al.
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Crossref

Data from <i>KEAP1/NFE2L2</i> Mutations Predict Lung Cancer Radiation Resistance That Can Be Targeted by Glutaminase Inhibition

2023-04-03 | Preprint
DOI: 10.1158/2159-8290.c.6547724.v1
Contributors: Michael S. Binkley; Young-Jun Jeon; Monica Nesselbush; Everett J. Moding; Barzin Y. Nabet; Diego Almanza; Christian Kunder; Henning Stehr; Christopher H. Yoo; Siyeon Rhee et al.
Source: check_circle
Crossref

Supplementary Figures 1-9 from <i>KEAP1/NFE2L2</i> Mutations Predict Lung Cancer Radiation Resistance That Can Be Targeted by Glutaminase Inhibition

2023-04-03 | Preprint
DOI: 10.1158/2159-8290.22534988
Contributors: Michael S. Binkley; Young-Jun Jeon; Monica Nesselbush; Everett J. Moding; Barzin Y. Nabet; Diego Almanza; Christian Kunder; Henning Stehr; Christopher H. Yoo; Siyeon Rhee et al.
Source: check_circle
Crossref

Supplementary Figures 1-9 from <i>KEAP1/NFE2L2</i> Mutations Predict Lung Cancer Radiation Resistance That Can Be Targeted by Glutaminase Inhibition

2023-04-03 | Preprint
DOI: 10.1158/2159-8290.22534988.v1
Contributors: Michael S. Binkley; Young-Jun Jeon; Monica Nesselbush; Everett J. Moding; Barzin Y. Nabet; Diego Almanza; Christian Kunder; Henning Stehr; Christopher H. Yoo; Siyeon Rhee et al.
Source: check_circle
Crossref

Supplementary Tables S1-S7 from <i>KEAP1/NFE2L2</i> Mutations Predict Lung Cancer Radiation Resistance That Can Be Targeted by Glutaminase Inhibition

2023-04-03 | Preprint
DOI: 10.1158/2159-8290.22534982
Contributors: Michael S. Binkley; Young-Jun Jeon; Monica Nesselbush; Everett J. Moding; Barzin Y. Nabet; Diego Almanza; Christian Kunder; Henning Stehr; Christopher H. Yoo; Siyeon Rhee et al.
Source: check_circle
Crossref

Supplementary Tables S1-S7 from <i>KEAP1/NFE2L2</i> Mutations Predict Lung Cancer Radiation Resistance That Can Be Targeted by Glutaminase Inhibition

2023-04-03 | Preprint
DOI: 10.1158/2159-8290.22534982.v1
Contributors: Michael S. Binkley; Young-Jun Jeon; Monica Nesselbush; Everett J. Moding; Barzin Y. Nabet; Diego Almanza; Christian Kunder; Henning Stehr; Christopher H. Yoo; Siyeon Rhee et al.
Source: check_circle
Crossref

TACOS: a novel approach for accurate prediction of cell-specific long noncoding RNAs subcellular localization

Briefings in Bioinformatics
2022-07-18 | Journal article
DOI: 10.1093/bib/bbac243
Contributors: Young-Jun Jeon; Md Mehedi Hasan; Hyun Woo Park; Ki Wook Lee; Balachandran Manavalan
Source: check_circle
Crossref

Promyelocytic Leukemia Proteins Regulate Fanconi Anemia Gene Expression

International Journal of Molecular Sciences
2021-07-21 | Journal article
DOI: 10.3390/ijms22157782
Contributors: Anudari Munkhjargal; Myung-Jin Kim; Da-Yeon Kim; Young-Jun Jeon; Young-Hoon Kee; Lark-Kyun Kim; Yong-Hwan Kim
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Crossref
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Preferred source (of 2)‎

Targeting Non-Oncogene Addiction for Cancer Therapy

Biomolecules
2021-01-20 | Journal article
DOI: 10.3390/biom11020129
Contributors: Hae Ryung Chang; Eunyoung Jung; Soobin Cho; Young-Jun Jeon; Yonghwan Kim
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

KEAP1/NFE2L2 Mutations Predict Lung Cancer Radiation Resistance That Can Be Targeted by Glutaminase Inhibition

Cancer Discovery
2020-12-01 | Journal article
DOI: 10.1158/2159-8290.CD-20-0282
Contributors: Michael S. Binkley; Young-Jun Jeon; Monica Nesselbush; Everett J. Moding; Barzin Y. Nabet; Diego Almanza; Christian Kunder; Henning Stehr; Christopher H. Yoo; Siyeon Rhee et al.
Source: check_circle
Crossref

Noninvasive Early Identification of Therapeutic Benefit from Immune Checkpoint Inhibition.

Cell
2020-10-01 | Journal article
DOI: 10.1016/j.cell.2020.09.001
PMID: 33007267
Source: Self-asserted source
Young-Jun Jeon

Extracellular RNA: Emerging roles in cancer cell communication and biomarkers.

Cancer letters
2020-09-08 | Journal article
DOI: 10.1016/j.canlet.2020.09.002
PMID: 32916182
Source: Self-asserted source
Young-Jun Jeon

Ablation of the Brca1-Palb2 Interaction Phenocopies Fanconi Anemia in Mice.

Cancer research
2020-07-30 | Journal article
DOI: 10.1158/0008-5472.can-20-0486
PMID: 32732220
Source: Self-asserted source
Young-Jun Jeon

Integrating genomic features for non-invasive early lung cancer detection.

Nature
2020-03-25 | Journal article
DOI: 10.1038/s41586-020-2140-0
PMID: 32269342
Source: Self-asserted source
Young-Jun Jeon

Functional significance of U2AF1 S34F mutations in lung adenocarcinomas.

Nature communications
2019-12-13 | Journal article
DOI: 10.1038/s41467-019-13392-y
PMID: 31836708
PMC: PMC6911043
Source: Self-asserted source
Young-Jun Jeon

DR4-Ser424 O-GlcNAcylation Promotes Sensitization of TRAIL-Tolerant Persisters and TRAIL-Resistant Cancer Cells to Death.

Cancer research
2019-04-15 | Journal article
DOI: 10.1158/0008-5472.can-18-1991
PMID: 30987996
Source: Self-asserted source
Young-Jun Jeon

The Comprehensive Roles of ATRANORIN, A Secondary Metabolite from the Antarctic Lichen Stereocaulon caespitosum, in HCC Tumorigenesis.

Molecules (Basel, Switzerland)
2019-04-10 | Journal article
DOI: 10.3390/molecules24071414
PMID: 30974882
PMC: PMC6480312
Source: Self-asserted source
Young-Jun Jeon

miRNA-mediated TUSC3 deficiency enhances UPR and ERAD to promote metastatic potential of NSCLC.

Nature communications
2018-11-30 | Journal article
DOI: 10.1038/s41467-018-07561-8
PMID: 30504895
PMC: PMC6269493
Source: Self-asserted source
Young-Jun Jeon

KRAS induces lung tumorigenesis through microRNAs modulation.

Cell death & disease
2018-02-13 | Journal article
DOI: 10.1038/s41419-017-0243-9
PMID: 29440633
PMC: PMC5833396
Source: Self-asserted source
Young-Jun Jeon

Comparative expression profiling of testis-enriched genes regulated during the development of spermatogonial cells.

PloS one
2017-04-17 | Journal article
DOI: 10.1371/journal.pone.0175787
PMID: 28414809
PMC: PMC5393594
Source: Self-asserted source
Young-Jun Jeon

ERK Activation Globally Downregulates miRNAs through Phosphorylating Exportin-5.

Cancer cell
2016-11-01 | Journal article
DOI: 10.1016/j.ccell.2016.10.001
PMID: 27846390
PMC: PMC5127275
Source: Self-asserted source
Young-Jun Jeon

APIP, an ERBB3-binding partner, stimulates erbB2-3 heterodimer formation to promote tumorigenesis.

Oncotarget
2016-04-01 | Journal article
DOI: 10.18632/oncotarget.7802
PMID: 26942872
PMC: PMC5008309
Source: Self-asserted source
Young-Jun Jeon

MicroRNA-224 is implicated in lung cancer pathogenesis through targeting caspase-3 and caspase-7.

Oncotarget
2015-09-01 | Journal article
DOI: 10.18632/oncotarget.5224
PMID: 26307684
PMC: PMC4673127
Source: Self-asserted source
Young-Jun Jeon

MYC-repressed long noncoding RNAs antagonize MYC-induced cell proliferation and cell cycle progression.

Oncotarget
2015-08-01 | Journal article
DOI: 10.18632/oncotarget.3909
PMID: 26003165
PMC: PMC4662455
Source: Self-asserted source
Young-Jun Jeon

MicroRNA-224 promotes tumor progression in nonsmall cell lung cancer.

Proceedings of the National Academy of Sciences of the United States of America
2015-07-17 | Journal article
DOI: 10.1073/pnas.1502068112
PMID: 26187928
PMC: PMC4534291
Source: Self-asserted source
Young-Jun Jeon

MicroRNA-148a reduces tumorigenesis and increases TRAIL-induced apoptosis in NSCLC.

Proceedings of the National Academy of Sciences of the United States of America
2015-06-29 | Journal article
DOI: 10.1073/pnas.1500886112
PMID: 26124099
PMC: PMC4507199
Source: Self-asserted source
Young-Jun Jeon

A set of NF-κB-regulated microRNAs induces acquired TRAIL resistance in lung cancer.

Proceedings of the National Academy of Sciences of the United States of America
2015-06-15 | Journal article
DOI: 10.1073/pnas.1504630112
PMID: 26080425
PMC: PMC4491797
Source: Self-asserted source
Young-Jun Jeon

The LIM-only transcription factor LMO2 determines tumorigenic and angiogenic traits in glioma stem cells.

Cell death and differentiation
2015-02-27 | Journal article
DOI: 10.1038/cdd.2015.7
PMID: 25721045
PMC: PMC4532780
Source: Self-asserted source
Young-Jun Jeon

Role of MYC-regulated long noncoding RNAs in cell cycle regulation and tumorigenesis.

Journal of the National Cancer Institute
2015-02-06 | Journal article
DOI: 10.1093/jnci/dju505
PMID: 25663692
PMC: PMC4402359
Source: Self-asserted source
Young-Jun Jeon

MicroRNAs in lung cancer.

World journal of methodology
2014-06-26 | Journal article
DOI: 10.5662/wjm.v4.i2.59
PMID: 25332906
PMC: PMC4202482
Source: Self-asserted source
Young-Jun Jeon

Long-range interaction and correlation between MYC enhancer and oncogenic long noncoding RNA CARLo-5.

Proceedings of the National Academy of Sciences of the United States of America
2014-03-04 | Journal article
DOI: 10.1073/pnas.1400350111
PMID: 24594601
PMC: PMC3964128
Source: Self-asserted source
Young-Jun Jeon

Insulin growth factor signaling is regulated by microRNA-486, an underexpressed microRNA in lung cancer.

Proceedings of the National Academy of Sciences of the United States of America
2013-08-26 | Journal article
DOI: 10.1073/pnas.1307107110
PMID: 23980150
PMC: PMC3773758
Source: Self-asserted source
Young-Jun Jeon

MiR-34a/c-Dependent PDGFR-α/β Downregulation Inhibits Tumorigenesis and Enhances TRAIL-Induced Apoptosis in Lung Cancer.

PloS one
2013-06-21 | Journal article
DOI: 10.1371/journal.pone.0067581
PMID: 23805317
PMC: PMC3689725
Source: Self-asserted source
Young-Jun Jeon

MicroRNAs/TP53 feedback circuitry in glioblastoma multiforme.

Proceedings of the National Academy of Sciences of the United States of America
2012-03-19 | Journal article
DOI: 10.1073/pnas.1202465109
PMID: 22431589
PMC: PMC3325690
Source: Self-asserted source
Young-Jun Jeon

Regulation in the targeting of TRAIL receptor 1 to cell surface via GODZ for TRAIL sensitivity in tumor cells.

Cell death and differentiation
2012-01-13 | Journal article
DOI: 10.1038/cdd.2011.209
PMID: 22240897
PMC: PMC3374084
Source: Self-asserted source
Young-Jun Jeon

EGFR and MET receptor tyrosine kinase-altered microRNA expression induces tumorigenesis and gefitinib resistance in lung cancers.

Nature medicine
2011-12-11 | Journal article
DOI: 10.1038/nm.2577
PMID: 22157681
PMC: PMC3467100
Source: Self-asserted source
Young-Jun Jeon

p53 regulates epithelial-mesenchymal transition through microRNAs targeting ZEB1 and ZEB2.

The Journal of experimental medicine
2011-04-25 | Journal article
DOI: 10.1084/jem.20110235
PMID: 21518799
PMC: PMC3092351
Source: Self-asserted source
Young-Jun Jeon

Ribosomal protein S6 is a selective mediator of TRAIL-apoptotic signaling.

Oncogene
2008-03-24 | Journal article
DOI: 10.1038/onc.2008.73
PMID: 18362888
Source: Self-asserted source
Young-Jun Jeon

AK2 activates a novel apoptotic pathway through formation of a complex with FADD and caspase-10.

Nature cell biology
2007-10-21 | Journal article
DOI: 10.1038/ncb1650
PMID: 17952061
Source: Self-asserted source
Young-Jun Jeon

Neuronal vulnerability of CLN3 deletion to calcium-induced cytotoxicity is mediated by calsenilin.

Human molecular genetics
2006-12-22 | Journal article
DOI: 10.1093/hmg/ddl466
PMID: 17189291
Source: Self-asserted source
Young-Jun Jeon

Peer review (7 reviews for 3 publications/grants)

Review activity for Cancer gene therapy. (1)
Review activity for Experimental and molecular medicine (1)
Review activity for Genes and genomics. (5)
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