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Scopus Author ID: 56226757800
GitHub: ReidTPowell

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Employment (2)

Texas A&M University: Houston, Texas, US

Post Doc (Center For Translational Cancer Research)
Employment
Source: Self-asserted source
Reid T. Powell

Texas A&M University: Houston, Texas, US

2020-12-01 to present | Research Assistant Professor (Translational Medical Science)
Employment
Source: Self-asserted source
Reid T. Powell

Education and qualifications (2)

Texas Tech University: Lubbock, TX, US

BS Biochemistry (Chemistry and Biochemistry)
Education
Source: Self-asserted source
Reid T. Powell

Texas A&M University College Station: Houston, TX, US

PhD, Medical Science
Education
Source: Self-asserted source
Reid T. Powell

Works (50 of 74)

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Page 1 of 2

Data from Gain-of-Function Chromatin Remodeling Activity of Oncogenic FOXL2<sup>C134W</sup> Reprograms Glucocorticoid Receptor Occupancy to Drive Granulosa Cell Tumors

2025-03-03 | Preprint
DOI: 10.1158/0008-5472.c.7700599
Contributors: Thomas Welte; Veena K. Vuttaradhi; Eleonora Y. Khlebus; Allison Brodsky; Alejandra Flores Legarreta; Joseph Celestino; Reid T. Powell; Clifford C. Stephan; Nghi Nguyen; Jian Li et al.
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Crossref

Gain-of-Function Chromatin Remodeling Activity of Oncogenic FOXL2C134W Reprograms Glucocorticoid Receptor Occupancy to Drive Granulosa Cell Tumors

Cancer Research
2025-03-03 | Journal article
DOI: 10.1158/0008-5472.CAN-24-2341
Contributors: Thomas Welte; Veena K. Vuttaradhi; Eleonora Y. Khlebus; Allison Brodsky; Alejandra Flores Legarreta; Joseph Celestino; Reid T. Powell; Clifford C. Stephan; Nghi Nguyen; Jian Li et al.
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Crossref

Supplementary Figures S1-16 from Gain-of-Function Chromatin Remodeling Activity of Oncogenic FOXL2<sup>C134W</sup> Reprograms Glucocorticoid Receptor Occupancy to Drive Granulosa Cell Tumors

2025-03-03 | Preprint
DOI: 10.1158/0008-5472.28523095
Contributors: Thomas Welte; Veena K. Vuttaradhi; Eleonora Y. Khlebus; Allison Brodsky; Alejandra Flores Legarreta; Joseph Celestino; Reid T. Powell; Clifford C. Stephan; Nghi Nguyen; Jian Li et al.
Source: check_circle
Crossref

Supplementary Tables S1-15 from Gain-of-Function Chromatin Remodeling Activity of Oncogenic FOXL2<sup>C134W</sup> Reprograms Glucocorticoid Receptor Occupancy to Drive Granulosa Cell Tumors

2025-03-03 | Preprint
DOI: 10.1158/0008-5472.28523092
Contributors: Thomas Welte; Veena K. Vuttaradhi; Eleonora Y. Khlebus; Allison Brodsky; Alejandra Flores Legarreta; Joseph Celestino; Reid T. Powell; Clifford C. Stephan; Nghi Nguyen; Jian Li et al.
Source: check_circle
Crossref

Chemical genetic analysis of enoxolone inhibition of C. difficile toxin production reveals adenine deaminase and ATP synthase as anti-virulence targets

Journal of Biological Chemistry
2024 | Journal article
Contributors: Marreddy, Ravi KR; Phelps, Gregory A; Churion, Kelly; Picker, Jonathan; Powell, Reid; Cherian, Philip T; Bowling, John J; Stephan, Clifford C; Lee, Richard E; Hurdle, Julian G
Source: Self-asserted source
Reid T. Powell

Cystic fibrosis cell models for high-throughput analysis and drug screening

Journal of Cystic Fibrosis
2024 | Journal article
Contributors: Liu, Aidi; Chokshi, Mithil; Nguyen, Nghi; Powell, Reid T; Stephan, Clifford C; Bao, Gang
Source: Self-asserted source
Reid T. Powell

Enhancing efficacy of the MEK inhibitor trametinib with paclitaxel in KRAS-mutated colorectal cancer

bioRxiv
2024 | Journal article
Contributors: Ghosh, Susmita; Fan, Fan; Powell, Reid T; Park, Yong; Stephan, Clifford C; Kopetz, Scott; Ellis, Lee; Bhattacharya, Rajat
Source: Self-asserted source
Reid T. Powell

EphA2-and HDAC-Targeted Combination Therapy in Endometrial Cancer

International journal of molecular sciences
2024 | Journal article
Contributors: Joseph, Robiya; Dasari, Santosh K; Umamaheswaran, Sujanitha; Mangala, Lingegowda S; Bayraktar, Emine; Rodriguez-Aguayo, Cristian; Wu, Yutuan; Nguyen, Nghi; Powell, Reid T; Sobieski, Mary et al.
Source: Self-asserted source
Reid T. Powell

Inhibition of GPX4 Induces the Death of p53-Mutant Triple-Negative Breast Cancer Cells

2024 | Journal article
Contributors: Tahaney, William M; Qian, Jing; Lanier, Amanda; Moyer, Cassandra L; Nguyen, Nghi; Ma, Yanxia; Hill, Jamal; Powell, Reid T; Stephan, Clifford C; Davies, Peter JA et al.
Source: Self-asserted source
Reid T. Powell

PDX models of TNBC established from pre-and post-therapy tumors identify vulnerabilities of resistant disease

Cancer Research
2024 | Journal article
Contributors: Rinkenbaugh, Amanda L; Qi, Yuan; Powell, Reid T; Cai, Shirong; Shao, Jiansu; Hancock, Faiza Baameur; Guo, Lei; Zhang, Xiaomei; Jeter-Jones, Sabrina; Fu, Chunxiao et al.
Source: Self-asserted source
Reid T. Powell

Small Molecule Screening Identifies HSP90 as a Modifier of RNA Foci in Myotonic Dystrophy Type 1

Molecular and Cellular Biology
2024 | Journal article
Contributors: Johnson, Sara J; Johnson, Hannah L; Powell, Reid T; Stephan, Clifford; Stossi, Fabio; Cooper, Thomas A
Source: Self-asserted source
Reid T. Powell

Targeting neddylation and sumoylation in chemoresistant triple negative breast cancer

NPJ Breast Cancer
2024 | Journal article
Contributors: Powell, Reid T; Rinkenbaugh, Amanda L; Guo, Lei; Cai, Shirong; Shao, Jiansu; Zhou, Xinhui; Zhang, Xiaomei; Jeter-Jones, Sabrina; Fu, Chunxiao; Qi, Yuan et al.
Source: Self-asserted source
Reid T. Powell

35P Enhancing efficacy of the MEK inhibitor trametinib in KRAS-mutated colorectal cancer cells

ESMO Open
2023 | Journal article
Contributors: Ellis, LM; Ghosh, S; Fan, F; Bhattacharya, R; Powell, R; Park, YS; Stephan, C
Source: Self-asserted source
Reid T. Powell

A Novel Transgenic Mouse Model of Down Syndrome Acute Lymphoblastic Leukemia Identifies Targetable Vulnerabilities

Blood
2023 | Journal article
Contributors: Junco, Jacob J; Rashid, Raushan; Terrell, Maci; Alozie, Michelle; Rochette, Max; Zorman, Barry; Sumazin, Pavel; Rowland, Lauren; Dettorre, Gino; Powell, Reid T et al.
Source: Self-asserted source
Reid T. Powell

Abstract B171: BX-795 enhances the efficacy of crizotinib in colorectal cancer cells by altering the activity of aurora kinases

Molecular Cancer Therapeutics
2023 | Journal article
Contributors: Ghosh, Susmita; Fan, Fan; Powell, Reid; Park, Yong Sung; Stephan, Clifford; Roszik, Jason; Ellis, Lee M; Bhattacharya, Rajat
Source: Self-asserted source
Reid T. Powell

Abstract P3060: Modeling Immune Checkpoint Inhibitor Associated Myocarditis In Vitro

Circulation Research
2023 | Journal article
Contributors: Jensen, Garrett; Wang, Xinjie; Zhao, Wei; Chen, Zhishi; Yu, Wei; Palaskas, Nicolas L; Stephan, Clifford; Powell, Reid; Wu, Joseph C; Luo, Weijia et al.
Source: Self-asserted source
Reid T. Powell

Abstract P6-10-19: Screening of GPCR-targeting drugs for repositioning in breast cancer

Cancer Research
2023 | Journal article
Contributors: Abdulkareem, Noor; Bhat, Raksha; Powell, Reid; Chikermane, Soumya; Yande, Soham; Trinh, Lisa; Abdelnasser, Hala; Ruiz, Alexis; Sobieski, Mary; Nguyen, Nghi et al.
Source: Self-asserted source
Reid T. Powell

Combination of EphA2-and Wee1-targeted therapies in Endometrial Cancer

International journal of molecular sciences
2023 | Journal article
Contributors: Dasari, Santosh K; Joseph, Robiya; Umamaheswaran, Sujanitha; Mangala, Lingegowda S; Bayraktar, Emine; Rodriguez-Aguayo, Cristian; Wu, Yutuan; Nguyen, Nghi; Powell, Reid T; Sobieski, Mary et al.
Source: Self-asserted source
Reid T. Powell

Combining MEK and SRC inhibitors for treatment of colorectal cancer demonstrate increased efficacy in vitro but not in vivo

Plos one
2023 | Journal article
Contributors: Fan, Fan; Ghosh, Susmita; Powell, Reid; Roszik, Jason; Park, Yongsun; Sobieski, Mary; Sorokin, Alexey; Stephan, Clifford; Kopetz, Scott; Ellis, Lee M et al.
Source: Self-asserted source
Reid T. Powell

Concurrent inactivation of PI3K and PLK1 is synergistic and overcomes acquired resistance to PI3K inhibitors in NOTCH1 MUT HNSCC

Cancer Research
2023 | Journal article
Contributors: Shah, Pooja A; Mazumdar, Tuhina; Powell, Reid T; Shen, Li; Wang, Jing; Stephen, Clifford C; Frederick, Mitchell J; Johnson, Faye M
Source: Self-asserted source
Reid T. Powell

Crizotinib enhances the efficacy of BX-795 identified by high-throughput screening of pan-active drugs in colorectal cancer cells

Cancer Research
2023 | Journal article
Contributors: Ghosh, Susmita; Fan, Fan; Roszik, Jason; Powell, Reid; Park, Yong; Stephan, Clifford; Ellis, Lee M; Bhattacharya, Rajat
Source: Self-asserted source
Reid T. Powell

Evolution of cisplatin resistance through coordinated metabolic reprogramming of the cellular reductive state

British journal of cancer
2023 | Journal article
Contributors: Yu, Wangie; Chen, Yunyun; Putluri, Nagireddy; Osman, Abdullah; Coarfa, Cristian; Putluri, Vasanta; Kamal, Abu HM; Asmussen, Jennifer Kay; Katsonis, Panagiotis; Myers, Jeffrey N et al.
Source: Self-asserted source
Reid T. Powell

Systematic high-throughput combination drug screen to enhance poly (ADP-ribose) polymerase (PARP) inhibitor efficacy in ovarian cancer.

2023 | Other
Contributors: Foster, Katherine; Dasari, Santosh K; Powell, Reid T; Nguyen, Nghi D; Sobieski, Mary; Stephan, Clifford; Bahl, Ashwani; Yap, Timothy A; Jazaeri, Amir A; Westin, Shannon Neville et al.
Source: Self-asserted source
Reid T. Powell

Targeting FOXL2C402G vulnerabilities in adult type ovarian granulosa cell tumors

Cancer Research
2023 | Journal article
Contributors: Welte, Thomas; Vuttaradhi, Veena; Khlebus, Eleonora; Lawson, Barrett; Hillman, Robert T; Nguyen, Nghi; Sobieski, Mary; Powell, Reid T; Stephan, Clifford
Source: Self-asserted source
Reid T. Powell

The Effects of Transplantation of the Spaceflight Intestinal Microbiome on Short Chain Fatty Acid Production, Lymphoid organ Immune Composition and Transport Kinetics

2023 | Journal article
Contributors: Powell, Reid; Endsley, Mark; Cromer, Walter Emerson
Source: Self-asserted source
Reid T. Powell

Vincristine enhances the efficacy of MEK inhibitors in preclinical models of KRAS-mutant colorectal cancer

Molecular cancer therapeutics
2023 | Journal article
Contributors: Ghosh, Susmita; Fan, Fan; Powell, Reid T; Roszik, Jason; Park, Yong Sung; Stephan, Clifford; Sebastian, Manu; Tan, Lin; Sorokin, Alexey V; Lorenzi, Philip L et al.
Source: Self-asserted source
Reid T. Powell

Abstract GS1-09: Inhibition of GPX4 induces preferential death of p53-mutant triple-negative breast cancer cells

Cancer Research
2022 | Journal article
Contributors: Tahaney, William M; Qian, Jing; Powell, Reid; Moyer, Cassandra L; Ma, Yanxia; Nguyen, Nghi; Hill, Jamal; Stephan, Clifford; Mazumdar, Abhijit; Davies, Peter JA et al.
Source: Self-asserted source
Reid T. Powell

Chemically targeting the redox switch in AP1 transcription factor $Δ$FOSB

Nucleic acids research
2022 | Journal article
Contributors: Kumar, Ashwani; Aglyamova, Galina; Yim, Yun Young; Bailey, Aaron O; Lynch, Haley M; Powell, Reid T; Nguyen, Nghi D; Rosenthal, Zachary; Zhao, Wen-Ning; Li, Yi et al.
Source: Self-asserted source
Reid T. Powell

Determining efficacy of combining the MEK inhibitor trametinib with vincristine identified by unbiased high throughput screening in RAS-mutated colorectal cancer cells

Cancer Research
2022 | Journal article
Contributors: Ghosh, Susmita; Fan, Fan; Roszik, Jason; Powell, Reid; Park, Yong; Stephan, Clifford; Ellis, Lee M; Bhattacharya, Rajat
Source: Self-asserted source
Reid T. Powell

Inhibition of GPX4 Induces the Death of p53-Mutant Triple-Negative Breast Cancer

2022 | Journal article
Contributors: Tahaney, William M; Qian, Jing; Moyer, Cassandra L; Nguyen, Nghi; Lanier, Amanda; Ma, Yanxia; Hill, Jamal; Powell, Reid T; Stephan, Clifford C; Mazumdar, Abhijit et al.
Source: Self-asserted source
Reid T. Powell

MOLECULAR LANDSCAPE OF A COMPREHENSIVE PANEL OF PEDIATRIC BRAIN CANCER PATIENT-DERIVED ORTHOTOPIC XENOGRAFT (PDOX) MODELS INFORM UNIQUE TARGETS FOR DRUG RESPONSIVENESS

NEURO-ONCOLOGY
2022 | Conference paper
Contributors: Braun, Frank K; Brabetz, Sebastian; Qi, Lin; Du, Yuchen; Kogiso, Mari; Zhang, Hui Yuan; Linday, Holly; Teo, Wanyee; Baxter, Patricia; Su, Jack MF et al.
Source: Self-asserted source
Reid T. Powell

Molecular pathways enhance drug response prediction using transfer learning from cell lines to tumors and patient-derived xenografts

Scientific Reports
2022 | Journal article
Contributors: Tang, Yi-Ching; Powell, Reid T; Gottlieb, Assaf
Source: Self-asserted source
Reid T. Powell

Rb deficient HPV+ HNSCC experienced enhanced sensitivity to aurora kinase inhibitors by altering the balance of MAD2 and TRIP13 levels

Cancer Research
2022 | Journal article
Contributors: Ghosh, Soma; Mazumdar, Tuhina; Xu, Wei; Powell, Reid T; Stephan, Clifford; Shen, Li; Pickering, Curtis R; Wang, Jing; Johnson, Faye M
Source: Self-asserted source
Reid T. Powell

Screening of GPCR drugs for repurposing in breast cancer

Frontiers in Pharmacology
2022 | Journal article
Contributors: Abdulkareem, Noor Mazin; Bhat, Raksha; Powell, Reid T; Chikermane, Soumya; Yande, Soham; Trinh, Lisa; Abdelnasser, Hala Y; Tabassum, Mantasha; Ruiz, Alexis; Sobieski, Mary et al.
Source: Self-asserted source
Reid T. Powell

The licorice metabolite enoxolone attenuates Clostridioides difficile pathophysiology by corrupting its metabolic and toxin production networks

bioRxiv
2022 | Journal article
Contributors: Marreddy, Ravi KR; Picker, Jonathan; Phelps, Gregory A; Powell, Reid; Cherian, Philip T; Bowling, John J; Stephan, Clifford C; Lee, Richard E; Hurdle, Julian G
Source: Self-asserted source
Reid T. Powell

deepOrganoid: A brightfield cell viability model for screening matrix-embedded organoids

SLAS Discovery
2022-03 | Journal article
DOI: 10.1016/j.slasd.2022.03.004
Contributors: Reid T. Powell; Micheline J. Moussalli; Lei Guo; Goeun Bae; Pankaj Singh; Clifford Stephan; Imad Shureiqi; Peter J. Davies
Source: Self-asserted source
Reid T. Powell

Combined inhibition of HMGCoA reductase and mitochondrial complex I induces tumor regression of BRAF inhibitor-resistant melanomas

Cancer & Metabolism
2022-02 | Journal article
DOI: 10.1186/s40170-022-00281-0
Contributors: Evelyn de Groot; Sruthy Varghese; Lin Tan; Barbara Knighton; Mary Sobieski; Nghi Nguyen; Yong Sung Park; Reid Powell; Philip L. Lorenzi; Bin Zheng et al.
Source: Self-asserted source
Reid T. Powell

Aurora kinase inhibitors cause cell death in HPV+ cells: A plausible treatment option for HPV+ cancers

Cancer Research
2021 | Journal article
Contributors: Mazumdar, Tuhina; Shen, Li; Xu, Wei; Ghosh, Soma; Powell, Reid T; Stephan, Clifford; Pickering, Curtis R; Myers, Jeffery N; Wang, Jing; Johnson, Faye M
Source: Self-asserted source
Reid T. Powell

Author Correction: Therapeutically actionable signaling node to rescue AURKA driven loss of primary cilia in VHL-deficient cells

Scientific Reports
2021 | Journal article
Contributors: Chowdhury, Pratim; Perera, Dimuthu; Powell, Reid T; Talley, Tia; Tripathi, Durga Nand; Park, Yong Sung; Mancini, Michael A; Davies, Peter; Stephan, Clifford; Coarfa, Cristian et al.
Source: Self-asserted source
Reid T. Powell

Endocrine disrupting chemicals differentially alter intranuclear dynamics and transcriptional activation of estrogen receptor-$α$

Iscience
2021 | Journal article
Contributors: Bolt, Michael J; Singh, Pankaj; Obkirchner, Caroline E; Powell, Reid T; Mancini, Maureen G; Szafran, Adam T; Stossi, Fabio; Mancini, Michael A
Source: Self-asserted source
Reid T. Powell

Identification of pathways that enhance cell death in NOTCH1-mutant HNSCC

Cancer Research
2021 | Journal article
Contributors: Shah, Pooja A; Mazumdar, Tuhina; Powell, Reid T; Shen, Li; Wang, Jing; Stephen, Clifford C; Frederick, Mitchell J; Johnson, Faye M
Source: Self-asserted source
Reid T. Powell

Targeting the Oncogenic Functions of an RNA-Binding Protein Involved in Hematologic Malignancies

Blood
2021 | Journal article
Contributors: Post, Sean M; Malaney, Prerna; Chan, Lauren; Zhang, Xiaorui; Link, Todd; Cho, Eun; Cerda, Juan; Aitken, Marisa J; Sobieski, Mary; Powell, Reid et al.
Source: Self-asserted source
Reid T. Powell

Therapeutically actionable signaling node to rescue AURKA driven loss of primary cilia in VHL-deficient cells

Scientific Reports
2021 | Journal article
Contributors: Chowdhury, Pratim; Perera, Dimuthu; Powell, Reid T; Talley, Tia; Tripathi, Durga Nand; Park, Yong Sung; Mancini, Michael A; Davies, Peter; Stephan, Clifford; Coarfa, Cristian et al.
Source: Self-asserted source
Reid T. Powell

Endocrine disrupting chemicals differentially alter intranuclear dynamics and transcriptional activation of estrogen receptor-$̆palpha$

iScience
2021-11 | Journal article
DOI: 10.1016/j.isci.2021.103227
Contributors: Michael J. Bolt; Pankaj Singh; Caroline E. Obkirchner; Reid T. Powell; Maureen G. Mancini; Adam T. Szafran; Fabio Stossi; Michael A. Mancini
Source: Self-asserted source
Reid T. Powell

Mammary-specific expression of Trim24 establishes a mouse model of human metaplastic breast cancer

Nature Communications
2021-09 | Journal article
DOI: 10.1038/s41467-021-25650-z
Contributors: Vrutant V. Shah; Aundrietta D. Duncan; Shiming Jiang; Sabrina A. Stratton; Kendra L. Allton; Clinton Yam; Abhinav Jain; Patrick M. Krause; Yue Lu; Shirong Cai et al.
Source: Self-asserted source
Reid T. Powell

Rational Combination of CRM1 Inhibitor Selinexor and Olaparib Shows Synergy in Ovarian Cancer Cell Lines and Mouse Models

Molecular Cancer Therapeutics
2021-09 | Journal article
DOI: 10.1158/1535-7163.mct-21-0370
Contributors: Katelyn F. Handley; Cristian Rodriguez-Aguayo; Shaolin Ma; Elaine Stur; Robiya Joseph; Emine Bayraktar; Santosh K. Dasari; Nghi Nguyen; Reid T. Powell; Mary Sobieski et al.
Source: Self-asserted source
Reid T. Powell

Morphological screening of mesenchymal mammary tumor organoids to identify drugs that reverse epithelial-mesenchymal transition

Nature Communications
2021-07 | Journal article
DOI: 10.1038/s41467-021-24545-3
Contributors: Na Zhao; Reid T. Powell; Xueying Yuan; Goeun Bae; Kevin P. Roarty; Fabio Stossi; Martina Strempfl; Michael J. Toneff; Hannah L. Johnson; Sendurai A. Mani et al.
Source: Self-asserted source
Reid T. Powell

A High-Throughput Approach to Identify Effective Systemic Agents for the Treatment of Anaplastic Thyroid Carcinoma

The Journal of Clinical Endocrinology & Metabolism
2021-06 | Journal article
DOI: 10.1210/clinem/dgab424
Contributors: Ying C Henderson; Abdallah S R Mohamed; Anastasios Maniakas; Yunyun Chen; Reid T Powell; Shaohua Peng; Maria Cardenas; Michelle D Williams; Diana Bell; Mark E Zafereo et al.
Source: Self-asserted source
Reid T. Powell

Therapeutically actionable signaling node to rescue AURKA driven loss of primary cilia in VHL-deficient cells

Scientific Reports
2021-05 | Journal article
DOI: 10.1038/s41598-021-89933-7
Contributors: Pratim Chowdhury; Dimuthu Perera; Reid T. Powell; Tia Talley; Durga Nand Tripathi; Yong Sung Park; Michael A. Mancini; Peter Davies; Clifford Stephan; Cristian Corfa et al.
Source: Self-asserted source
Reid T. Powell

Abstract B20: Unbiased high-throughput screenings to identify combination therapies targeting RAS-mutated colorectal cancer

Molecular Cancer Research
2020 | Journal article
Contributors: Powell, Reid; Fan, Fan; Sobieski, Mary; Brunell, David; Wang, Rui; Ye, Xiangcang; Stephan, Clifford; Ellis, Lee M; Bhattacharya, Rajat
Source: Self-asserted source
Reid T. Powell
Items per page:
Page 1 of 2

Peer review (3 reviews for 2 publications/grants)

Review activity for iScience. (2)
Review activity for Nature communications (1)
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