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Biography

Miguel C Seabra, MD, PhD, is a leading researcher in the field of cellular and molecular medicine. MS holds a PhD from University of Texas Southwestern Medical Center (1992), where he was an Assistant Professor, before moving to the Faculty of Medicine, Imperial College London where he became Full Professor and head of Section until 2007. MS is now Full Professor at the Medical School of the Universidade Nova de Lisboa, Portugal, where he coordinates research in Cellular and Molecular Medicine and holds several chairs.
MS has a long track record in vision sciences and has been the leader of a pioneering clinical trial of retinal gene therapy. Moreover, MS have provided remarkable contributions for the elucidation of the cellular and molecular mechanisms underlying Choroideremia, AMD and DR (Diabetic Retinopathy).
MS was president of Fundação para a Ciência e a Tecnologia (FCT) from 2012 to 2015, the portuguese public funding agency for science and research in Portugal.

Activities

Employment (5)

Fundação Champalimaud: Lisbon, PT

2021-06-01 to present | Head of Global Eye Initiative
Employment
Source: Self-asserted source
Miguel C Seabra

UCL Institute of Ophthalmology, University College London: London, GB

2016-01-01 to present | Invited Professor
Employment
Source: Self-asserted source
Miguel C Seabra

Nova Medical School, Universidade Nova de Lisboa: Lisboa, Lisboa, PT

2007-01-01 to present | Professor (CEDOC - Center for Chronic Diseases Research)
Employment
Source: Self-asserted source
Miguel C Seabra

Imperial College London: London, London, GB

1997-09-01 to 2015-12-31 | Senior Lecturer then Professor then Invited Professor (NHLI, Faculty of Medicine)
Employment
Source: Self-asserted source
Miguel C Seabra

University of Texas Southwestern Medical Center: Dallas, Texas, US

1994-09-01 to 1997-08-31 | Assistant Professor (Molecular Genetics)
Employment
Source: Self-asserted source
Miguel C Seabra

Education and qualifications (2)

University of Texas Southwestern Medical Center: Dallas, TX, US

1988-09-01 to 1992-09-01 | PhD (Molecular genetics)
Education
Source: Self-asserted source
Miguel C Seabra

Universidade Nova de Lisboa: Lisboa, PT

1980-09-01 to 1986-07-31 | M.D. (Faculdade de Ciências Médicas)
Education
Source: Self-asserted source
Miguel C Seabra

Professional activities (2)

Science Europe: Brussels, BE

2014-05-31 to 2015-05-31 | President
Distinction
Source: Self-asserted source
Miguel C Seabra

Fundação para a Ciência e a Tecnologia: Lisboa, Lisboa, PT

2012-01-01 to 2015-04-10 | President
Distinction
Source: Self-asserted source
Miguel C Seabra

Funding (10)

NRF2 as a novel therapeutic target in early and intermediate age-related macular degeneration (731keuros)

2022-12 to 2025-11 | Contract
Fundación Bancaria Caixa d’Estalvis i Pensions de Barcelona (Barcelona, ES)
Source: Self-asserted source
Miguel C Seabra

Lysosome dysfunction in age-related diseases (240 keuros)

2018-10-01 to 2022-06-30 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

PTDC/MED-PAT/30385/2017

Source: check_circle
CIÊNCIAVITAE

Lysosome dysfunction in age-related diseases (240 keuros)

2018-10 to 2022-06 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
Source: check_circle
CIÊNCIAVITAE

Co-PI: A exocitose de lisossomas disfuncionais como novo paradigma na patogénese da aterosclerose

2018-10 to 2021-09 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

PTDC/MED-PAT/29395/2017

Source: check_circle
CIÊNCIAVITAE

Co-PI: Mecanismos moleculares de internalização e processamento de melanina por queratinócitos

2018-10 to 2021-09 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

PTDC/BIA-CEL/29765/2017

Source: check_circle
CIÊNCIAVITAE

Co-PI: Recovering neuronal function and promoting neuroprotection in diabetic retinopathy

2018-10 to 2021-09 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

PTDC/MED-PAT/29656/2017

Source: check_circle
CIÊNCIAVITAE

Correction of lysosomal dysfunction in Retinal Pigmented Epithelial (RPE) cells (325 Keuros)

2017-09-01 to 2019-11-30 | Contract
Boehringer Ingelheim Auslandsbeteiligungs GmbH (Ingelheim, DE)
GRANT_NUMBER:

__

Source: check_circle
CIÊNCIAVITAE

Bioengineered in vitro model of retinal pigmented epithelium of human eye (100 Keuros)

2017-05-08 to 2020-05-07 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

M-ERA-NET2/0005/2016

Source: check_circle
CIÊNCIAVITAE

Molecular mechanisms of organelle motility

2008-01 to 2010-12 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

PTDC/BIA-BCM/73146/2006

Source: check_circle
CIÊNCIAVITAE

Molecular mechanisms of formation of the parasitic vacuole in Malaria infection

2007-10 to 2010-03 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

PTDC/SAU-MII/72027/2006

Source: check_circle
CIÊNCIAVITAE

Peer review (25 reviews for 13 publications/grants)

Review activity for Biomolecules. (1)
Review activity for Cell death and disease. (1)
Review activity for Cells. (2)
Review activity for Communications biology. (1)
Review activity for European journal of biochemistry. (1)
Review activity for European journal of pharmacology. (2)
Review activity for Expert opinion on biological therapy (1)
Review activity for International journal of molecular sciences. (1)
Review activity for Nature communications (1)
Review activity for Pigment cell & melanoma research. (5)
Review activity for Proceedings of the National Academy of Sciences of the United States of America. (2)
Review activity for The journal of investigative dermatology. (5)
Review activity for Traffic. (2)