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Employment (3)

University of Cambridge: Cambridge, GB

2018-09-01 to present | Lecturer (Pharmacology)
Employment
Source: Self-asserted source
Paul Miller

University of Oxford: Oxford, Oxfordshire, GB

2010-04-01 to 2018-07-01 | Postdoctoral researcher (Nuffield Department of Medicine, Division of Structural Biology)
Employment
Source: Self-asserted source
Paul Miller

University College London: London, London, GB

2005-01-01 to 2010-02-28 | Postdoctoral researcher (Neuroscience, Physiology and Pharmacology)
Employment
Source: Self-asserted source
Paul Miller

Education and qualifications (2)

University College London: London, London, GB

2000-10-01 to 2004-12-20 | Wellcome Trust 4-Year PhD in Neuroscience (Neuroscience, Physiology and Pharmacology)
Education
Source: Self-asserted source
Paul Miller

Imperial College London: London, London, GB

1996-09-01 to 2000-06-30 | BSc Biochemistry with Year in Industry (First Class) (Biochemistry)
Education
Source: Self-asserted source
Paul Miller

Funding (5)

Delivering next-generation pharmacological tools against GABAA receptors

2021-11-10 to 2024-11-09 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
URL: https://app.dimensions.ai/details/grant/grant.9727633
GRANT_NUMBER: BB/V013963/1
Source: Self-asserted source
Paul Miller via DimensionsWizard

Understanding and engineering central nervous system shuttles to target biologics against GABAA receptors

2020-01 to 2022-10 | Grant
Rosetrees Trust (London, GB)
GRANT_NUMBER:

RC-IaT-2020 100003
Source: Self-asserted source
Paul Miller

Developing novel modulators of GABA-A receptors

2019-05-01 to 2021-04-30 | Grant
Academy of Medical Sciences (London, GB)
URL: https://app.dimensions.ai/details/grant/grant.9554249
GRANT_NUMBER: SBF004\1074
Source: Self-asserted source
Paul Miller via DimensionsWizard

Structural analysis of human GABAA receptors

2015-04-30 to 2018-04-29 | Grant
Biotechnology and Biological Sciences Research Council (n/a, GB)
URL: https://grants.uberresearch.com/501100000268/C4F65C80-AC0E-41C5-A873-FE1F116527C0/Structural-analysis-of-human-GABAA-receptors
GRANT_NUMBER: grant.BB/M024709/1
Source: Self-asserted source
Paul Miller via DimensionsWizard

Determination of the structure of GABAARs and interacting partners

2010-04 to 2013-04 | Award
Wellcome Trust (London, GB)
Source: Self-asserted source
Paul Miller

Works (12)

Publisher Correction: Mechanisms of inhibition and activation of extrasynaptic αβ GABAA receptors

Nature
2022-04-14 | Journal article
DOI: 10.1038/s41586-022-04663-8
Contributors: Vikram Babu Kasaragod; Martin Mortensen; Steven W. Hardwick; Ayla A. Wahid; Valentina Dorovykh; Dimitri Y. Chirgadze; Trevor G. Smart; Paul S. Miller
Source: check_circle
Crossref

Mechanisms of inhibition and activation of extrasynaptic αβ GABAA receptors

Nature
2022-02-17 | Journal article
DOI: 10.1038/s41586-022-04402-z
Contributors: Vikram Babu Kasaragod; Martin Mortensen; Steven W. Hardwick; Ayla A. Wahid; Valentina Dorovykh; Dimitri Y. Chirgadze; Trevor G. Smart; Paul S. Miller
Source: check_circle
Crossref

Heteromeric GABAA receptor structures in positively-modulated active states

2018-06-04 | Other
DOI: 10.1101/338343
Contributors: Paul S. Miller; Simonas Masiulis; Tomas Malinauskas; Abhay Kotecha; Shanlin Rao; Sreenivas Chavali; Luigi De Colibus; Els Pardon; Saad Hannan; Suzanne Scott et al.
Source: check_circle
Crossref

Structural basis for GABAA receptor potentiation by neurosteroids

Nature Structural & Molecular Biology
2017-11-09 | Journal article
DOI: 10.1038/nsmb.3484
Contributors: Paul S Miller; Suzanne Scott; Simonas Masiulis; Luigi De Colibus; Els Pardon; Jan Steyaert; A Radu Aricescu
Source: check_circle
Crossref

Structural basis of Smoothened regulation by its extracellular domains.

Nature
2016-07 | Journal article
DOI: 10.1038/nature18934
PMID: 27437577
PMC: PMC4970916
Contributors: Byrne EFX; Sircar R; Miller PS; Hedger G; Luchetti G; Nachtergaele S; Tully MD; Mydock-McGrane L; Covey DF; Rambo RP et al.
Source: Self-asserted source
Paul Miller via Europe PubMed Central

Crystal structure of a human GABAA receptor.

Nature
2014-08 | Journal article
DOI: 10.1038/nature13293
PMID: 24909990
PMC: PMC4167603
Contributors: Miller PS; Aricescu AR
Source: Self-asserted source
Paul Miller via Europe PubMed Central

Binding, activation and modulation of Cys-loop receptors.

Trends in pharmacological sciences
2010-04 | Journal article
DOI: 10.1016/j.tips.2009.12.005
PMID: 20096941
Contributors: Miller PS; Smart TG
Source: Self-asserted source
Paul Miller via Europe PubMed Central

Mapping a molecular link between allosteric inhibition and activation of the glycine receptor.

Nature structural & molecular biology
2008-10 | Journal article
DOI: 10.1038/nsmb.1492
PMID: 18806798
Contributors: Miller PS; Topf M; Smart TG
Source: Self-asserted source
Paul Miller via Europe PubMed Central

Molecular basis for zinc potentiation at strychnine-sensitive glycine receptors.

The Journal of biological chemistry
2005-11 | Journal article
DOI: 10.1074/jbc.m508303200
PMID: 16144831
Contributors: Miller PS; Da Silva HM; Smart TG
Source: Self-asserted source
Paul Miller via Europe PubMed Central

Molecular determinants of glycine receptor alphabeta subunit sensitivities to Zn2+-mediated inhibition.

The Journal of physiology
2005-08 | Journal article
DOI: 10.1113/jphysiol.2005.088575
PMID: 15905212
Contributors: Miller PS; Beato M; Harvey RJ; Smart TG
Source: Self-asserted source
Paul Miller via Europe PubMed Central

Zn2+ ions: modulators of excitatory and inhibitory synaptic activity.

The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry
2004-10 | Journal article
DOI: 10.1177/1073858404263463
PMID: 15359010
Contributors: Smart TG; Hosie AM; Miller PS
Source: Self-asserted source
Paul Miller via Europe PubMed Central

Differential agonist sensitivity of glycine receptor alpha2 subunit splice variants.

British journal of pharmacology
2004-09 | Journal article
DOI: 10.1038/sj.bjp.0705875
PMID: 15302677
PMC: PMC1575261
Contributors: Miller PS; Harvey RJ; Smart TG
Source: Self-asserted source
Paul Miller via Europe PubMed Central

Peer review (2 reviews for 2 publications/grants)

Review activity for Nature communications (1)
Review activity for Nature structural & molecular biology. (1)
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