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Employment (3)

University of Wollongong: Wollongong, NSW, AU

2018-01-01 to present | Research Fellow
Employment
Source: Self-asserted source
Harshad Ghodke

University of Wollongong: Wollongong, NSW, AU

2015-04-14 to 2017-12-31 | Associate Research Fellow (School of Chemistry)
Employment
Source: Self-asserted source
Harshad Ghodke

Rijksuniversiteit Groningen Faculteit voor Wiskunde en Natuurwetenschappen: Groningen, Groningen, NL

2014-01-01 to 2015-06-01 | Postdoctoral Researcher
Employment
Source: Self-asserted source
Harshad Ghodke

Education and qualifications (3)

University of Pittsburgh: Pittsburgh, PA, US

2009-08 to 2013-12 | Doctor of Philosophy (Molecular Biophysics and Structural Biology program)
Education
Source: Self-asserted source
Harshad Ghodke

Carnegie Mellon University: Pittsburgh, PA, US

2007-08 to 2008-12 | Master of Science (Chemical Engineering)
Education
Source: Self-asserted source
Harshad Ghodke

Indian Institute of Technology Bombay: Mumbai, Maharashtra, IN

2003-07-26 to 2007-08-09 | Bachelor of Technology (Chemical Engineering)
Education
Source: Self-asserted source
Harshad Ghodke

Works (29)

Development of a generalisable tryptophan-optimised quenchbody biosensor based on a synthetic nanobody library

2024-03-27 | Preprint
Contributors: Jordan Harry Cater; Nehad Elsalamouny; Ghada H Mansour; Sebastian Hutchinson; Conall Mc Guinness; Stefan H. Mueller; Richard Raymond Spinks; Nirukshan Shanmugam; Adeline Pichard-Kostuch; Harshad Ghodke et al.
Source: check_circle
Crossref

Structural characterisation of the complete cycle of sliding clamp loading inEscherichia coli

2023-07-21 | Preprint
Contributors: Zhi-Qiang Xu; Slobodan Jergic; Allen T.Y. Lo; Alok C. Pradhan; Simon H.J. Brown; James C. Bouwer; Harshad Ghodke; Peter J. Lewis; Gökhan Tolun; Aaron J. Oakley et al.
Source: check_circle
Crossref

Single-molecule visualization of stalled replication-fork rescue by the Escherichia coli Rep helicase

Nucleic Acids Research
2023-04-24 | Journal article
Contributors: Kelsey S Whinn; Zhi-Qiang Xu; Slobodan Jergic; Nischal Sharma; Lisanne M Spenkelink; Nicholas E Dixon; Antoine M van Oijen; Harshad Ghodke
Source: check_circle
Crossref

Single-molecule visualization of stalled replication-fork rescue by theEscherichia coliRep helicase

2022-12-05 | Preprint
Contributors: Kelsey S. Whinn; Zhi-Qiang Xu; Slobodan Jergic; Nischal Sharma; Lisanne M. Spenkelink; Nicholas E. Dixon; Antoine M. van Oijen; Harshad Ghodke
Source: check_circle
Crossref

Single-molecule studies of helicases and translocases in prokaryotic genome-maintenance pathways

DNA Repair
2021-12 | Journal article
Contributors: Kelsey S. Whinn; Antoine M. van Oijen; Harshad Ghodke
Source: check_circle
Crossref

Single-molecule live-cell imaging reveals RecB-dependent function of DNA polymerase IV in double strand break repair.

Nucleic acids research
2020-09-01 | Journal article
Source: Self-asserted source
Harshad Ghodke

Single-molecule imaging reveals molecular coupling between transcription and DNA repair machinery in live cells

Nature Communications
2020-03-20 | Journal article
Contributors: Han Ngoc Ho; Antoine M. van Oijen; Harshad Ghodke
Source: check_circle
Crossref

Single-molecule live-cell imaging visualizes parallel pathways of prokaryotic nucleotide excision repair

Nature Communications
2020-03-20 | Journal article
Contributors: Harshad Ghodke; Han Ngoc Ho; Antoine M. van Oijen
Source: check_circle
Crossref

Spy-ing on Cas9: Single-molecule tools reveal the enzymology of Cas9

Current Opinion in Biomedical Engineering
2019-12 | Journal article
Contributors: Kelsey S. Whinn; Antoine M. van Oijen; Harshad Ghodke
Source: check_circle
Crossref

Identification of Multiple Kinetic Populations of DNA-Binding Proteins in Live Cells

Biophysical Journal
2019-09 | Journal article
Contributors: Han N. Ho; Daniel Zalami; Jürgen Köhler; Antoine M. van Oijen; Harshad Ghodke
Source: check_circle
Crossref

Nuclease dead Cas9 is a programmable roadblock for DNA replication.

Scientific reports
2019-09-16 | Journal article
Source: Self-asserted source
Harshad Ghodke

RecFOR epistasis group: RecF and RecO have distinct localizations and functions in Escherichia coli.

Nucleic acids research
2019-04-01 | Journal article
Source: Self-asserted source
Harshad Ghodke

Spatial and temporal organization of RecA in the Escherichia coli DNA-damage response

eLife
2019-02-05 | Journal article
Contributors: Harshad Ghodke; Bishnu P Paudel; Jacob S Lewis; Slobodan Jergic; Kamya Gopal; Zachary J Romero; Elizabeth A Wood; Roger Woodgate; Michael M Cox; Antoine M van Oijen
Source: check_circle
Crossref

Design of DNA rolling-circle templates with controlled fork topology to study mechanisms of DNA replication.

Analytical biochemistry
2018-07-18 | Journal article
Source: Self-asserted source
Harshad Ghodke

The transcription-repair coupling factor Mfd associates with RNA polymerase in the absence of exogenous damage

Nature Communications
2018-04-20 | Journal article
Contributors: Han N. Ho; Antoine M. van Oijen; Harshad Ghodke
Source: check_circle
Crossref

Resolving the Gordian Knot: Srs2 Strips Intermediates Formed during Homologous Recombination.

Trends in biochemical sciences
2017-12-28 | Journal article
Source: Self-asserted source
Harshad Ghodke

Single-molecule live-cell imaging of bacterial DNA repair and damage tolerance.

Biochemical Society transactions
2017-12-01 | Journal article
Source: Self-asserted source
Harshad Ghodke

Single-Molecule Specific Mislocalization of Red Fluorescent Proteins in Live Escherichia coli

Biophysical Journal
2016 | Journal article
EID:

2-s2.0-84994017728

Contributors: Ghodke, H.; Caldas, V.E.A.; Punter, C.M.; van Oijen, A.M.; Robinson, A.
Source: Self-asserted source
Harshad Ghodke via Scopus - Elsevier

ISBatch: A batch-processing platform for data analysis and exploration of live-cell single-molecule microscopy images and other hierarchical datasets

Molecular BioSystems
2015 | Journal article
EID:

2-s2.0-84941911598

Contributors: Caldas, V.E.A.; Punter, C.M.; Ghodke, H.; Robinson, A.; Van Oijen, A.M.
Source: Self-asserted source
Harshad Ghodke via Scopus - Elsevier

Regulation of Mutagenic DNA Polymerase V Activation in Space and Time

PLoS Genetics
2015 | Journal article
EID:

2-s2.0-84940778030

Contributors: Robinson, A.; McDonald, J.P.; Caldas, V.E.A.; Patel, M.; Wood, E.A.; Punter, C.M.; Ghodke, H.; Cox, M.M.; Woodgate, R.; Goodman, M.F. et al.
Source: Self-asserted source
Harshad Ghodke via Scopus - Elsevier

Early integration of the individual student in academic activities: A novel classroom concept for graduate education in molecular biophysics and structural biology

BMC Biophysics
2014 | Journal article
EID:

2-s2.0-84928157350

Contributors: Leuba, S.H.; Carney, S.M.; Dahlburg, E.M.; Eells, R.J.; Ghodke, H.; Yanamala, N.; Schauer, G.; Klein-Seetharaman, J.
Source: Self-asserted source
Harshad Ghodke via Scopus - Elsevier

Single-molecule analysis reveals human UV-damaged DNA-binding protein (UV-DDB) dimerizes on DNA via multiple kinetic intermediates

Proceedings of the National Academy of Sciences of the United States of America
2014 | Journal article
EID:

2-s2.0-84899825410

Contributors: Ghodke, H.; Wang, H.; Hsieh, C.L.; Woldemeskel, S.; Watkins, S.C.; Rapić-Otrin, V.; Van Houten, B.
Source: Self-asserted source
Harshad Ghodke via Scopus - Elsevier

Backbone-branched DNA building blocks for facile angular control in nanostructures

ACS Nano
2013 | Journal article
EID:

2-s2.0-84878296407

Contributors: Paredes, E.; Zhang, X.; Ghodke, H.; Yadavalli, V.K.; Das, S.R.
Source: Self-asserted source
Harshad Ghodke via Scopus - Elsevier

Real-time single-molecule imaging reveals a direct interaction between UvrC and UvrB on DNA tightropes

Nucleic Acids Research
2013 | Journal article
EID:

2-s2.0-84877300985

Contributors: Hughes, C.D.; Wang, H.; Ghodke, H.; Simons, M.; Towheed, A.; Peng, Y.; Van Houten, B.; Kad, N.M.
Source: Self-asserted source
Harshad Ghodke via Scopus - Elsevier

The Shu complex interacts with Rad51 through the Rad51 paralogues Rad55-Rad57 to mediate error-free recombination

Nucleic Acids Research
2013 | Journal article
EID:

2-s2.0-84877256636

Contributors: Godin, S.; Wier, A.; Kabbinavar, F.; Bratton-Palmer, D.S.; Ghodke, H.; Van Houten, B.; Vandemark, A.P.; Bernstein, K.A.
Source: Self-asserted source
Harshad Ghodke via Scopus - Elsevier

Damaged DNA induced UV-damaged DNA-binding protein (UV-DDB) dimerization and its roles in chromatinized DNA repair

Proceedings of the National Academy of Sciences of the United States of America
2012 | Journal article
EID:

2-s2.0-84867376482

Contributors: Yeh, J.I.; Levine, A.S.; Du, S.; Chinte, U.; Ghodke, H.; Wang, H.; Shi, H.; Hsieh, C.L.; Conway, J.F.; Van Houten, B. et al.
Source: Self-asserted source
Harshad Ghodke via Scopus - Elsevier

Single molecule studies of physiologically relevant telomeric tails reveal POT1 mechanism for promoting G-quadruplex unfolding

Journal of Biological Chemistry
2011 | Journal article
EID:

2-s2.0-79953219455

Contributors: Wang, H.; Nora, G.J.; Ghodke, H.; Opresko, P.L.
Source: Self-asserted source
Harshad Ghodke via Scopus - Elsevier

Room temperature synthesis of titanium dioxide nanoparticles of different phases in water in oil microemulsion

Colloids and Surfaces A: Physicochemical and Engineering Aspects
2010 | Journal article
EID:

2-s2.0-77956882353

Contributors: Keswani, R.K.; Ghodke, H.; Sarkar, D.; Khilar, K.C.; Srinivasa, R.S.
Source: Self-asserted source
Harshad Ghodke via Scopus - Elsevier

The I-tetraplex building block: Rational design and controlled fabrication of robust 1D DNA scaffolds through non-Watson-Crick interactions

Angewandte Chemie - International Edition
2007 | Journal article
EID:

2-s2.0-34250862100

Contributors: Ghodke, H.B.; Krishnan, R.; Vignesh, K.; Kumar, G.V.P.; Narayana, C.; Krishnan, Y.
Source: Self-asserted source
Harshad Ghodke via Scopus - Elsevier