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Employment (1)

University College Dublin: Dublin, IE

2016-09-01 to present | Professor of Gynaecological Oncoloy (School of Medicine)
Employment
Source: Self-asserted source
Donal Brennan

Education and qualifications (2)

University College Dublin: Dublin, IE

2008-10-01 | PhD (Cancer Biology0 (School of Biomolecular and Biomedical Science)
Education
Source: Self-asserted source
Donal Brennan

University College Dublin: Dublin, IE

1997-09-01 to 2003-01-06 | MB BCh BAO (School of Medicine)
Education
Source: Self-asserted source
Donal Brennan

Professional activities (4)

Royal College of Physicians of Ireland: Dublin, IE

Service
Source: Self-asserted source
Donal Brennan

Royal College of Obstetricians and Gynaecologists: London, London, GB

Membership
Source: Self-asserted source
Donal Brennan

International Gynecologic Cancer Society: Chicago, US

Membership
Source: Self-asserted source
Donal Brennan

European Society of Gynaecological Oncology: Geneva, CH

Membership
Source: Self-asserted source
Donal Brennan

Works (50)

Maternal morbidity in placenta accreta spectrum following introduction of a multi-disciplinary service compared to standard care: an Irish perspective.

Irish journal of medical science
2021-01-15 | Journal article
DOI: 10.1007/s11845-020-02473-3
PMID: 33449329
Source: Self-asserted source
Donal Brennan

Mid-luteal uterine artery Doppler indices in the prediction of pregnancy outcome in nulliparous women undergoing assisted reproduction.

Human fertility (Cambridge, England)
2021-01-13 | Journal article
DOI: 10.1080/14647273.2021.1872111
PMID: 33439056
Source: Self-asserted source
Donal Brennan

Multidisciplinary Surgical Approach to Increase Complete Cytoreduction Rates for Advanced Ovarian Cancer in a Tertiary Gynecologic Oncology Center.

Annals of surgical oncology
2021-01-10 | Journal article
DOI: 10.1245/s10434-020-09494-3
PMID: 33423175
Source: Self-asserted source
Donal Brennan

Signaling Dynamics Regulating Crosstalks between T-Cell Activation and Immune Checkpoints.

Trends in cell biology
2020-12-30 | Journal article
DOI: 10.1016/j.tcb.2020.12.001
PMID: 33388215
Source: Self-asserted source
Donal Brennan

Perspectives, fears and expectations of patients with gynaecological cancers during the COVID-19 pandemic: A Pan-European study of the European Network of Gynaecological Cancer Advocacy Groups (ENGAGe).

Cancer medicine
2020-11-18 | Journal article
DOI: 10.1002/cam4.3605
PMID: 33205595
PMC: PMC7753798
Source: Self-asserted source
Donal Brennan

Management of menopausal symptoms and ovarian function preservation in women with gynecological cancer.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
2020-10-30 | Journal article
DOI: 10.1136/ijgc-2020-002032
PMID: 33127864
Source: Self-asserted source
Donal Brennan

The impact of accurately timed mid-luteal endometrial injury in nulligravid women undergoing their first or second embryo transfer.

Irish journal of medical science
2020-10-22 | Journal article
DOI: 10.1007/s11845-020-02414-0
PMID: 33090349
Source: Self-asserted source
Donal Brennan

The Molecular Effects of a High Fat Diet on Endometrial Tumour Biology

Life
2020-09 | Journal article | Author
DOI: 10.3390/life10090188
Contributors: Michael Wilkinson; Piriyah Sinclair; Ludmilla Dellatorre-Teixeira; Patrick Swan; Eoin Brennan; Bruce Moran; Dirk Wedekind; Paul Downey; Kieran Sheahan; Emer Conroy et al.
Source: check_circle
Multidisciplinary Digital Publishing Institute

A life changing experience: An interpretative phenomenological analysis of women's experiences of placenta accreta spectrum.

European journal of obstetrics, gynecology, and reproductive biology
2020-09-13 | Journal article
DOI: 10.1016/j.ejogrb.2020.09.014
PMID: 32950888
Source: Self-asserted source
Donal Brennan

Dysregulation of the interleukin-17A pathway in endometrial tissue from women with unexplained infertility affects pregnancy outcome following assisted reproductive treatment.

Human reproduction (Oxford, England)
2020-08-01 | Journal article
DOI: 10.1093/humrep/deaa111
PMID: 32614049
Source: Self-asserted source
Donal Brennan

Fertility-sparing treatment in early endometrial cancer: current state and future strategies.

Obstetrics & gynecology science
2020-07-08 | Journal article
DOI: 10.5468/ogs.19169
PMID: 32689770
PMC: PMC7393748
Source: Self-asserted source
Donal Brennan

Patient perceptions and understanding of obesity related endometrial cancer

Gynecologic Oncology Reports
2020-05 | Journal article
DOI: 10.1016/j.gore.2020.100545
Contributors: M. Wilkinson; S. Murphy; P. Sinclair; H Heneghan; C.W. le Roux; D.J. Brennan
Source: check_circle
Crossref

Improving response to progestin treatment of low-grade endometrial cancer.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
2020-05-06 | Journal article
DOI: 10.1136/ijgc-2020-001309
PMID: 32381512
Source: Self-asserted source
Donal Brennan

Prophylactic human papillomavirus vaccination to prevent recurrence of cervical intraepithelial neoplasia: a meta-analysis.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
2020-04-09 | Journal article
DOI: 10.1136/ijgc-2020-001197
PMID: 32276936
Source: Self-asserted source
Donal Brennan

The Impact of Sarcopenia and Low Muscle Attenuation on Overall Survival in Epithelial Ovarian Cancer: A Systematic Review and Meta-analysis.

Annals of surgical oncology
2020-03-27 | Journal article
DOI: 10.1245/s10434-020-08382-0
PMID: 32221737
Source: Self-asserted source
Donal Brennan

Primary cytoreductive surgery with or without hyperthermic intraperitoneal chemotherapy (HIPEC) for FIGO stage III epithelial ovarian cancer: OVHIPEC-2, a phase III randomized clinical trial.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
2020-03-23 | Journal article
DOI: 10.1136/ijgc-2020-001231
PMID: 32205449
Source: Self-asserted source
Donal Brennan

Mitogen-Activated Protein Kinase (MAPK) and Obesity-Related Cancer

International Journal of Molecular Sciences
2020-02-13 | Journal article
DOI: 10.3390/ijms21041241
Contributors: Fionán Donohoe; Michael Wilkinson; Eva Baxter; Donal J. Brennan
Source: check_circle
Crossref
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Preferred source (of 2)‎

Evaluating liquid biopsies for methylomic profiling of prostate cancer.

Epigenetics
2020-01-31 | Journal article
DOI: 10.1080/15592294.2020.1712876
PMID: 32000564
PMC: PMC7574384
Source: Self-asserted source
Donal Brennan

FKBPL-based peptide, ALM201, targets angiogenesis and cancer stem cells in ovarian cancer.

British journal of cancer
2019-11-27 | Journal article
DOI: 10.1038/s41416-019-0649-5
PMID: 31772325
PMC: PMC7000737
Source: Self-asserted source
Donal Brennan

A meta-analysis of morbidity and mortality in primary cytoreductive surgery compared to neoadjuvant chemotherapy in advanced ovarian malignancy

Gynecologic Oncology
2019-09 | Journal article
DOI: 10.1016/j.ygyno.2019.07.011
Contributors: Helena C. Bartels; Ailin C. Rogers; Veronica McSharry; Ruaidhri McVey; Thomas Walsh; Donal O'Brien; William D. Boyd; Donal J. Brennan
Source: check_circle
Crossref

Morbidity and mortality in women with advanced ovarian cancer who underwent primary cytoreductive surgery compared to cytoreductive surgery for recurrent disease: a meta-analysis.

Pleura and peritoneum
2019-06-28 | Journal article
DOI: 10.1515/pp-2019-0014
PMID: 31417960
PMC: PMC6693481
Source: Self-asserted source
Donal Brennan

Molecular basis of distinct oestrogen responses in endometrial and breast cancer.

Endocrine-related cancer
2019-01-01 | Journal article
DOI: 10.1530/erc-17-0563
PMID: 30121621
Source: Self-asserted source
Donal Brennan

Association of Implementing a Multidisciplinary Team Approach in the Management of Morbidly Adherent Placenta With Maternal Morbidity and Mortality.

Obstetrics and gynecology
2018-11-01 | Journal article
DOI: 10.1097/aog.0000000000002865
PMID: 30234729
Source: Self-asserted source
Donal Brennan

Gut adaptation after metabolic surgery and its influences on the brain, liver and cancer.

Nature reviews. Gastroenterology & hepatology
2018-10-01 | Journal article
DOI: 10.1038/s41575-018-0057-y
PMID: 30181611
Source: Self-asserted source
Donal Brennan

Ovarian Cancer Screening Editorial

Irish medical journal
2018-09-10 | Journal article
PMID: 30547506
Source: Self-asserted source
Donal Brennan

Placenta Accreta Spectrum: A Review of Pathology, Molecular Biology, and Biomarkers

Disease Markers
2018-07-03 | Journal article
DOI: 10.1155/2018/1507674
Contributors: Helena C. Bartels; James D. Postle; Paul Downey; Donal J. Brennan
Source: check_circle
Crossref

Incidental Thoracic Findings on Routine Computed Tomography in Epithelial Ovarian Cancer.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
2018-07-01 | Journal article
DOI: 10.1097/igc.0000000000001268
PMID: 29664842
Source: Self-asserted source
Donal Brennan

A Borderline Ovarian Tumour in a Patient with Classic Bladder Exstrophy; a Case Report.

Irish medical journal
2018-02-09 | Journal article
PMID: 29952444
Source: Self-asserted source
Donal Brennan

ER and PR expression and survival after endometrial cancer.

Gynecologic oncology
2017-12-06 | Journal article
DOI: 10.1016/j.ygyno.2017.11.027
PMID: 29217139
Source: Self-asserted source
Donal Brennan

G9a drives hypoxia-mediated gene repression for breast cancer cell survival and tumorigenesis.

Proceedings of the National Academy of Sciences of the United States of America
2017-06-19 | Journal article
DOI: 10.1073/pnas.1618706114
PMID: 28630300
PMC: PMC5502591
Source: Self-asserted source
Donal Brennan

Surgical safety and personal costs in morbidly obese, multimorbid patients diagnosed with early-stage endometrial cancer having a hysterectomy.

Gynecologic oncology research and practice
2016-02-09 | Journal article
DOI: 10.1186/s40661-016-0023-8
PMID: 27231573
PMC: PMC4880831
Source: Self-asserted source
Donal Brennan

Cell line and patient-derived xenograft models reveal elevated CDCP1 as a target in high-grade serous ovarian cancer.

British journal of cancer
2016-02-04 | Journal article
DOI: 10.1038/bjc.2015.471
PMID: 26882065
PMC: PMC4815773
Source: Self-asserted source
Donal Brennan

Germline polymorphisms in an enhancer of PSIP1 are associated with progression-free survival in epithelial ovarian cancer.

Oncotarget
2016-02-01 | Journal article
DOI: 10.18632/oncotarget.7047
PMID: 26840454
PMC: PMC4872719
Source: Self-asserted source
Donal Brennan

Downregulation of the cancer susceptibility protein WRAP53β in epithelial ovarian cancer leads to defective DNA repair and poor clinical outcome.

Cell death & disease
2015-10-01 | Journal article
DOI: 10.1038/cddis.2015.250
PMID: 26426684
PMC: PMC4632285
Source: Self-asserted source
Donal Brennan

Serum HE4 detects recurrent endometrial cancer in patients undergoing routine clinical surveillance.

BMC cancer
2015-02-06 | Journal article
DOI: 10.1186/s12885-015-1028-0
PMID: 25655024
PMC: PMC4342867
Source: Self-asserted source
Donal Brennan

Peroxiredoxin-1 protects estrogen receptor α from oxidative stress-induced suppression and is a protein biomarker of favorable prognosis in breast cancer.

Breast cancer research : BCR
2014-07-10 | Journal article
DOI: 10.1186/bcr3691
PMID: 25011585
PMC: PMC4226972
Source: Self-asserted source
Donal Brennan

Serum HE4 as a prognostic marker in endometrial cancer--a population based study.

Gynecologic oncology
2013-11-06 | Journal article
DOI: 10.1016/j.ygyno.2013.10.036
PMID: 24211402
Source: Self-asserted source
Donal Brennan

Feasibility and outcomes of ureteroureterostomy and extravesical ureteroneocystostomy as part of radical surgery for infiltrating gynecologic disease.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
2013-07-01 | Journal article
DOI: 10.1097/igc.0b013e3182993790
PMID: 23792608
Source: Self-asserted source
Donal Brennan

Systematic antibody generation and validation via tissue microarray technology leading to identification of a novel protein prognostic panel in breast cancer.

BMC cancer
2013-04-02 | Journal article
DOI: 10.1186/1471-2407-13-175
PMID: 23547718
PMC: PMC3668187
Source: Self-asserted source
Donal Brennan

Targeting tumor-infiltrating macrophages decreases tumor-initiating cells, relieves immunosuppression, and improves chemotherapeutic responses.

Cancer research
2012-12-05 | Journal article
DOI: 10.1158/0008-5472.can-12-2731
PMID: 23221383
PMC: PMC3563931
Source: Self-asserted source
Donal Brennan

miR-187 is an independent prognostic factor in breast cancer and confers increased invasive potential in vitro.

Clinical cancer research : an official journal of the American Association for Cancer Research
2012-10-11 | Journal article
DOI: 10.1158/1078-0432.ccr-12-1420
PMID: 23060431
Source: Self-asserted source
Donal Brennan

Natural history, management, and outcomes of peripartum cardiomyopathy: an Irish single-center cohort study.

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
2012-09-25 | Journal article
DOI: 10.3109/14767058.2012.726299
PMID: 22978474
Source: Self-asserted source
Donal Brennan

Maternal and fetal cocaine- and amphetamine-regulated transcript in diabetic and non-diabetic pregnancy.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology
2012-02-14 | Journal article
DOI: 10.3109/09513590.2011.652245
PMID: 22332848
Source: Self-asserted source
Donal Brennan

The cocaine- and amphetamine-regulated transcript mediates ligand-independent activation of ERα, and is an independent prognostic factor in node-negative breast cancer.

Oncogene
2011-12-05 | Journal article
DOI: 10.1038/onc.2011.519
PMID: 22139072
PMC: PMC5739589
Source: Self-asserted source
Donal Brennan

High nuclear RBM3 expression is associated with an improved prognosis in colorectal cancer.

Proteomics. Clinical applications
2011-12-01 | Journal article
DOI: 10.1002/prca.201100020
PMID: 21956899
Source: Self-asserted source
Donal Brennan

A dynamic inflammatory cytokine network in the human ovarian cancer microenvironment.

Cancer research
2011-11-07 | Journal article
DOI: 10.1158/0008-5472.can-11-2178
PMID: 22065722
PMC: PMC3252703
Source: Self-asserted source
Donal Brennan

Identification of a myometrial molecular profile for dystocic labor.

BMC pregnancy and childbirth
2011-10-16 | Journal article
DOI: 10.1186/1471-2393-11-74
PMID: 21999197
PMC: PMC3207913
Source: Self-asserted source
Donal Brennan

The tumour suppressor SOX11 is associated with improved survival among high grade epithelial ovarian cancers and is regulated by reversible promoter methylation.

BMC cancer
2011-09-24 | Journal article
DOI: 10.1186/1471-2407-11-405
PMID: 21943380
PMC: PMC3187763
Source: Self-asserted source
Donal Brennan

RBM3-regulated genes promote DNA integrity and affect clinical outcome in epithelial ovarian cancer.

Translational oncology
2011-08-01 | Journal article
DOI: 10.1593/tlo.11106
PMID: 21804916
PMC: PMC3140008
Source: Self-asserted source
Donal Brennan

Interleukin-6 as a therapeutic target in human ovarian cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research
2011-07-27 | Journal article
DOI: 10.1158/1078-0432.ccr-11-0945
PMID: 21795409
PMC: PMC3182554
Source: Self-asserted source
Donal Brennan
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