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Scopus Author ID: 6602432096

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Works (36)

The Legionella pneumophila effector DenR hijacks the host NRas proto-oncoprotein to downregulate MAPK signaling

Cell Reports
2024-04 | Journal article
DOI: 10.1016/j.celrep.2024.114033
Contributors: Stephanie S. Lehman; Chad D. Williamson; Trisha Tucholski; Nicole A. Ellis; Sabrina Bouchard; Michal Jarnik; Morgan Allen; Aleksandra Nita-Lazar; Matthias P. Machner
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Crossref

A randomized multiplex CRISPRi-Seq approach for the identification of critical combinations of genes

eLife
2023-12-14 | Journal article
DOI: 10.7554/eLife.86903.3
Contributors: Nicole A Ellis; Kevin S Myers; Jessica Tung; Anne Davidson Ward; Kathryn Johnston; Katherine E Bonnington; Timothy J Donohue; Matthias P Machner
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Crossref

A randomized multiplex CRISPRi-Seq approach for the identification of critical combinations of genes

eLife
2023-12-14 | Journal article
DOI: 10.7554/eLife.86903
Contributors: Nicole A Ellis; Kevin S Myers; Jessica Tung; Anne Davidson Ward; Kathryn Johnston; Katherine E Bonnington; Timothy J Donohue; Matthias P Machner
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Crossref

VpdC is a ubiquitin-activated phospholipase effector that regulates Legionella vacuole expansion during infection

Proceedings of the National Academy of Sciences
2022-11-29 | Journal article
DOI: 10.1073/pnas.2209149119
Contributors: Xiao Li; D. Eric Anderson; Yuen-Yan Chang; Michal Jarnik; Matthias P. Machner
Source: check_circle
Crossref

A multiplex CRISPR interference tool for virulence gene interrogation in Legionella pneumophila

Communications Biology
2021-02-04 | Journal article
DOI: 10.1038/s42003-021-01672-7
Contributors: Nicole A. Ellis; Byoungkwan Kim; Jessica Tung; Matthias P. Machner
Source: check_circle
Crossref

Structural insight into the membrane targeting domain of the Legionella  deAMPylase SidD

PLOS Pathogens
2020-08-27 | Journal article
DOI: 10.1371/journal.ppat.1008734
Contributors: Igor Tascón; Tomoko Kubori; Xiao Li; María Lucas; D’anna Nelson; Ander Vidaurrazaga; Yi-Han Lin; Adriana L. Rojas; Aitor Hierro; Matthias P. Machner
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Crossref

The Legionella kinase LegK7 exploits the Hippo pathway scaffold protein MOB1A for allostery and substrate phosphorylation

Proceedings of the National Academy of Sciences
2020-06-23 | Journal article
DOI: 10.1073/pnas.2000497117
Contributors: Pei-Chung Lee; Ksenia Beyrakhova; Caishuang Xu; Michal T. Boniecki; Mitchell H. Lee; Chisom J. Onu; Andrey M. Grishin; Matthias P. Machner; Miroslaw Cygler
Source: check_circle
Crossref

A multiplex CRISPR interference tool for virulence gene interrogation in an intracellular pathogen

2020-06-18 | Preprint
DOI: 10.1101/2020.06.17.157628
Contributors: Nicole A. Ellis; Byoungkwan Kim; Matthias P. Machner
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Crossref

Biology and Pathogenesis of Legionella

Frontiers Research Topics
2018 | Book
DOI: 10.3389/978-2-88945-661-1
Part of ISBN: 9782889456611
Part of ISSN: 1664-8714
Contributors: Hayley Newton; Elizabeth Hartland; Matthias Machner
Source: Self-asserted source
Matthias Machner via Crossref Metadata Search

Editorial: Biology and pathogenesis of Legionella

Frontiers in Cellular and Infection Microbiology
2018 | Journal article
DOI: 10.3389/fcimb.2018.00328
EID:

2-s2.0-85054466187
Contributors: Newton, H.J.; Hartland, E.L.; MacHner, M.P.
Source: Self-asserted source
Matthias Machner via Scopus - Elsevier

Legionella effector AnkX interacts with host nuclear protein PLEKHN1

BMC Microbiology
2018 | Journal article
DOI: 10.1186/s12866-017-1147-7
EID:

2-s2.0-85041963953
Contributors: Yu, X.; Noll, R.R.; Romero Dueñas, B.P.; Allgood, S.C.; Barker, K.; Caplan, J.L.; Machner, M.P.; LaBaer, J.; Qiu, J.; Neunuebel, M.R.
Source: Self-asserted source
Matthias Machner via Scopus - Elsevier

RavN is a member of a previously unrecognized group of Legionella pneumophila E3 ubiquitin ligases

PLoS Pathogens
2018 | Journal article
DOI: 10.1371/journal.ppat.1006897
EID:

2-s2.0-85042694799
Contributors: Lin, Y.-H.; Lucas, M.; Evans, T.R.; Abascal-Palacios, G.; Doms, A.G.; Beauchene, N.A.; Rojas, A.L.; Hierro, A.; Machner, M.P.
Source: Self-asserted source
Matthias Machner via Scopus - Elsevier
grade
Preferred source (of 2)‎

The Legionella Effector Kinase LegK7 Hijacks the Host Hippo Pathway to Promote Infection

Cell Host and Microbe
2018 | Journal article
DOI: 10.1016/j.chom.2018.08.004
EID:

2-s2.0-85052079120
Contributors: Lee, P.-C.; Machner, M.P.
Source: Self-asserted source
Matthias Machner via Scopus - Elsevier

Discovering protein-protein interactions using nucleic acid programmable protein arrays

Current Protocols in Cell Biology
2017 | Journal article
DOI: 10.1002/cpcb.14
EID:

2-s2.0-85025079428
Contributors: Tang, Y.; Qiu, J.; Machner, M.; LaBaer, J.
Source: Self-asserted source
Matthias Machner via Scopus - Elsevier

Exploitation of the host cell ubiquitin machinery by microbial effector proteins

Journal of Cell Science
2017 | Journal article
DOI: 10.1242/jcs.188482
EID:

2-s2.0-85020536911
Contributors: Lin, Y.-H.; Machner, M.P.
Source: Self-asserted source
Matthias Machner via Scopus - Elsevier
grade
Preferred source (of 2)‎

Molecular mechanism for the subversion of the retromer coat by the Legionella effector RidL

Proceedings of the National Academy of Sciences of the United States of America
2017 | Journal article
DOI: 10.1073/pnas.1715361115
EID:

2-s2.0-85039729982
Contributors: Romano-Moreno, M.; Rojas, A.L.; Williamson, C.D.; Gershlick, D.C.; Lucas, M.; Isupov, M.N.; Bonifacino, J.S.; MacHner, M.P.; Hierro, A.
Source: Self-asserted source
Matthias Machner via Scopus - Elsevier

Infection biology: Small RNA with a large impact

Nature
2016 | Journal article
DOI: 10.1038/nature16872
EID:

2-s2.0-84956644162
Contributors: Machner, M.P.; Storz, G.
Source: Self-asserted source
Matthias Machner via Scopus - Elsevier

Host cell-catalyzed S-palmitoylation mediates Golgi targeting of the legionella ubiquitin ligase GobX

Journal of Biological Chemistry
2015 | Journal article
DOI: 10.1074/jbc.M115.637397
EID:

2-s2.0-84944464030
Contributors: Lin, Y.-H.; Doms, A.G.; Cheng, E.; Kim, B.; Evans, T.R.; Machner, M.P.
Source: Self-asserted source
Matthias Machner via Scopus - Elsevier

Host-pathogen interaction profiling using self-assembling human protein arrays

Journal of Proteome Research
2015 | Journal article
DOI: 10.1021/pr5013015
EID:

2-s2.0-84926512827
Contributors: Yu, X.; Decker, K.B.; Barker, K.; Neunuebel, M.R.; Saul, J.; Graves, M.; Westcott, N.; Hang, H.; Labaer, J.; Qiu, J. et al.
Source: Self-asserted source
Matthias Machner via Scopus - Elsevier

Ingenious strategies of microbial pathogens

Molecular biology of the cell
2015 | Journal article
DOI: 10.1091/mbc.E15-01-0011
EID:

2-s2.0-84965083262
Contributors: Morrissette, N.S.; Machner, M.P.
Source: Self-asserted source
Matthias Machner via Scopus - Elsevier

A novel probe for phosphatidylinositol 4-phosphate reveals multiple pools beyond the Golgi

Journal of Cell Biology
2014 | Journal article
DOI: 10.1083/jcb.201312072
EID:

2-s2.0-84901650366
Contributors: Hammond, G.R.V.; Machner, M.P.; Balla, T.
Source: Self-asserted source
Matthias Machner via Scopus - Elsevier

Structural basis for the recruitment and activation of the Legionella phospholipase VipD by the host GTPase Rab5

Proceedings of the National Academy of Sciences of the United States of America
2014 | Journal article
DOI: 10.1073/pnas.1405391111
EID:

2-s2.0-84906699384
Contributors: Lucas, M.; Gaspar, A.H.; Pallara, C.; Rojas, A.L.; Fernańdez-Recio, J.; Machner, M.P.; Hierro, A.
Source: Self-asserted source
Matthias Machner via Scopus - Elsevier

VipD is a Rab5-activated phospholipase a<inf>1</inf> that protects Legionella pneumophila from endosomal fusion

Proceedings of the National Academy of Sciences of the United States of America
2014 | Journal article
DOI: 10.1073/pnas.1316376111
EID:

2-s2.0-84897011367
Contributors: Gaspar, A.H.; Machner, M.P.
Source: Self-asserted source
Matthias Machner via Scopus - Elsevier

Structural Basis for Rab1 De-AMPylation by the Legionella pneumophila Effector SidD

PLoS Pathogens
2013 | Journal article
DOI:

10.1371/journal.ppat.1003382
Contributors: Chen, Y.; Tascón, I.; Neunuebel, M.R.; Pallara, C.; Brady, J.; Kinch, L.N.; Fernández-Recio, J.; Rojas, A.L.; Machner, M.P.; Hierro, A.
Source: Self-asserted source
Matthias Machner via Scopus - Elsevier

Targeting of the small GTPase Rab6A' by the legionella pneumophila effector LidA

Infection and Immunity
2013 | Journal article
DOI:

10.1128/IAI.00157-13
Contributors: Chen, Y.; Machner, M.P.
Source: Self-asserted source
Matthias Machner via Scopus - Elsevier

Legionella pneumophila lida affects nucleotide binding and activity of the host GTPase Rab1

Journal of Bacteriology
2012 | Journal article
DOI:

10.1128/JB.06306-11
Contributors: Neunuebel, M.R.; Mohammadi, S.; Jarnik, M.; Machner, M.P.
Source: Self-asserted source
Matthias Machner via Scopus - Elsevier

The taming of a Rab GTPase by Legionella pneumophila

Small GTPases
2012 | Journal article
DOI:

10.1126/science.1207
Contributors: Ramona Neunuebel, M.; Machner, M.P.
Source: Self-asserted source
Matthias Machner via Scopus - Elsevier

De-AMPylation of the small GTPase Rab1 by the pathogen Legionella pneumophila

Science
2011 | Journal article
DOI:

10.1126/science.1207193
Contributors: Neunuebel, M.R.; Chen, Y.; Gaspar, A.H.; Backlund Jr., P.S.; Yergey, A.; Machner, M.P.
Source: Self-asserted source
Matthias Machner via Scopus - Elsevier

The E Block motif is associated with Legionella pneumophila translocated substrates

Cellular Microbiology
2011 | Journal article
DOI:

10.1111/j.1462-5822.2010.01531.x
Contributors: Huang, L.; Boyd, D.; Amyot, W.M.; Hempstead, A.D.; Luo, Z.-Q.; O'Connor, T.J.; Chen, C.; Machner, M.; Montminy, T.; Isberg, R.R.
Source: Self-asserted source
Matthias Machner via Scopus - Elsevier

A bifunctional bacterial protein links GDI displacement to Rab1 activation

Science
2007 | Journal article
DOI:

10.1126/science.1149121
Contributors: Machner, M.P.; Isberg, R.R.
Source: Self-asserted source
Matthias Machner via Scopus - Elsevier

Targeting of Host Rab GTPase Function by the Intravacuolar Pathogen Legionella pneumophila

Developmental Cell
2006 | Journal article
DOI:

10.1016/j.devcel.2006.05.013
Contributors: Machner, M.P.; Isberg, R.R.
Source: Self-asserted source
Matthias Machner via Scopus - Elsevier

Folding and stability of the leucine-rich repeat domain of internalin B from Listeria monocytogenes

Journal of Molecular Biology
2004 | Journal article
DOI:

10.1016/j.jmb.2004.01.044
Contributors: Freiberg, A.; Machner, M.P.; Pfeil, W.; Schubert, W.-D.; Heinz, D.W.; Seckler, R.
Source: Self-asserted source
Matthias Machner via Scopus - Elsevier

Aromatic amino acids at the surface of lnlB are essential for host cell invasion by Listeria monocytogenes

Molecular Microbiology
2003 | Journal article
DOI:

10.1046/j.1365-2958.2003.03532.x
Contributors: Machner, M.P.; Frese, S.; Schubert, W.-D.; Orian-Rousseau, V.; Gherardi, E.; Wehland, J.; Niemann, H.H.; Heinz, D.W.
Source: Self-asserted source
Matthias Machner via Scopus - Elsevier

Structure of internalin, a major invasion protein of Listeria monocytogenes, in complex with its human receptor E-cadherin

Cell
2002 | Journal article
DOI:

10.1016/S0092-8674(02)01136-4
Contributors: Schubert, W.-D.; Urbanke, C.; Ziehm, T.; Beier, V.; Machner, M.P.; Domann, E.; Wehland, J.; Chakraborty, T.; Heinz, D.W.
Source: Self-asserted source
Matthias Machner via Scopus - Elsevier

ActA from Listeria monocytogenes Can Interact with Up to Four EnaNASP Homology 1 Domains Simultaneously

Journal of Biological Chemistry
2001 | Journal article
DOI:

10.1074/jbc.M104279200
Contributors: Machner, M.P.; Urbanke, C.; Barzik, M.; Otten, S.; Sechi, A.S.; Wehland, J.; Heinz, D.W.
Source: Self-asserted source
Matthias Machner via Scopus - Elsevier

Electron microscopy studies of cell-wall-anchored cellulose (Avicel)- binding protein (AbpS) from Streptomyces reticuli

Applied and Environmental Microbiology
1999 | Journal article
EID: 2-s2.0-0032985167
Contributors: Walter, S.; Rohde, M.; Machner, M.; Schrempf, H.
Source: Self-asserted source
Matthias Machner via Scopus - Elsevier
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