Personal information

Vascular anomalies, vascular biology, PI3K, TIE2, GNAQ
United States

Activities

Employment (4)

Cincinnati Children's Hospital Medical Center: Cincinnati, OH, US

2021-11-11 to present | Associate Professor (Experimental Hematology and Cancer Biology)
Employment
Source: Self-asserted source
Elisa Boscolo

Cincinnati Children's Hospital Medical Center: Cincinnati, OH, US

2014-05-01 to 2021-11-11 | Assistant Professor (Experimental hematology)
Employment
Source: Self-asserted source
Elisa Boscolo

Children's Hospital Boston: Boston, MA, US

2009-11 to 2014-04 | Instructor (Vascular Biology)
Employment
Source: Self-asserted source
Elisa Boscolo

Children's Hospital Boston: Boston, MA, US

2006-05 to 2009-10 | Post-doctoral fellow (Vascular Biology)
Employment
Source: Self-asserted source
Elisa Boscolo

Education and qualifications (2)

Università degli Studi di Padova: Padova, Veneto, IT

2003-01 to 2006-04 | PhD (Anatomy)
Education
Source: Self-asserted source
Elisa Boscolo

Università degli Studi di Padova: Padova, Veneto, IT

1996-10 to 2002-03 | BS (Genetics)
Education
Source: Self-asserted source
Elisa Boscolo

Professional activities (3)

American Journal of Hematology: Boston, MA, US

Editorial Board member
Service
Source: Self-asserted source
Elisa Boscolo

ISSVA: Milwaukee, WI, US

2014 to present
Membership
Source: Self-asserted source
Elisa Boscolo

NAVBO: Germantown, MD, US

2009 to present
Membership
Source: Self-asserted source
Elisa Boscolo

Funding (1)

Venous Malformations (VM): A Murine Mdoel to Identify Therapies to Target Aberrant Venous Development

2013-06-12 to 2025-01-31 | Grant
National Heart Lung and Blood Institute (Bethesda, US)
GRANT_NUMBER: R01HL117952
Source: Self-asserted source
Elisa Boscolo via DimensionsWizard

Works (35)

Protocol for three-dimensional whole-mount imaging of the vascular network in the intestinal muscle

STAR Protocols
2024-09 | Journal article
Contributors: Sandra Schrenk; Lindsay J. Bischoff; Elisa Boscolo
Source: check_circle
Crossref

NRASQ61R mutation in human endothelial cells causes vascular malformations

Angiogenesis
2022-08 | Journal article
Contributors: Elisa Boscolo; Patricia Pastura; Sandra Schrenk; Jillian Goines; Rachael Kang; Devin Pillis; Punam Malik; Timothy D. Le Cras
Source: check_circle
Crossref

Kaposiform lymphangiomatosis treated with multimodal therapy improves coagulopathy and reduces blood angiopoietin‐2 levels

Pediatric Blood & Cancer
2020-09 | Journal article
Contributors: Janet Crane; Jackie Manfredo; Elisa Boscolo; Mara Coyan; Clifford Takemoto; Maxim Itkin; Denise M. Adams; Timothy D. Le Cras
Source: check_circle
Crossref

Constitutively active PIK3CA mutations are expressed by lymphatic and vascular endothelial cells in capillary lymphatic venous malformation

Angiogenesis
2020-08-30 | Journal article
Contributors: Timothy D. Le Cras; Jillian Goines; Nora Lakes; Patricia Pastura; Adrienne M. Hammill; Denise M. Adams; Elisa Boscolo
Source: check_circle
Crossref

Signaling pathways and inhibitors of cells from patients with kaposiform lymphangiomatosis

Pediatric Blood & Cancer
2019-08 | Journal article
Contributors: Elisa Boscolo; Patricia Pastura; Kathryn Glaser; Jillian Goines; Adrienne M. Hammill; Denise M. Adams; Peter Dickie; Belinda Hsi Dickie; Timothy D. Le Cras
Source: check_circle
Crossref

Constitutive Active Mutant TIE2 Induces Enlarged Vascular Lumen Formation with Loss of Apico-basal Polarity and Pericyte Recruitment

Scientific Reports
2019-08-26 | Journal article
Contributors: Yuqi Cai; Sandra Schrenk; Jillian Goines; George E. Davis; Elisa Boscolo
Source: check_circle
Crossref

Cellular and molecular mechanisms of PIK3CA-related vascular anomalies

Vascular Biology
2019-06 | Journal article
Part of ISSN: 2516-5658
Source: Self-asserted source
Elisa Boscolo

Ponatinib Combined With Rapamycin Causes Regression of Murine Venous Malformation

Arteriosclerosis, Thrombosis, and Vascular Biology
2019-03 | Journal article
Part of ISSN: 1079-5642
Contributors: Xian Li; Yuqi Cai; Jillian Goines; Patricia Pastura; Lars Brichta; Adam Lane; Timothy D. Le Cras; Elisa Boscolo
Source: Self-asserted source
Elisa Boscolo via Crossref Metadata Search

A xenograft model for venous malformation

Angiogenesis
2018-11-21 | Journal article
Contributors: Jillian Goines; Xian Li; Yuqi Cai; Paula Mobberley-Schuman; Megan Metcalf; Steven J. Fishman; Denise M. Adams; Adrienne M. Hammill; Elisa Boscolo
Source: check_circle
Crossref

Combined mTOR and MEK inhibition is an effective therapy in a novel mouse model for angiosarcoma

Oncotarget
2018-04 | Journal article
Part of ISSN: 1949-2553
Contributors: Michelle L. Chadwick; Adam Lane; Dana Thomas; Amanda R. Smith; Angela R. White; Dominique Davidson; Yuxin Feng; Elisa Boscolo; Yi Zheng; Denise M. Adams et al.
Source: Self-asserted source
Elisa Boscolo via Crossref Metadata Search

Cooperation between human fibrocytes and endothelial colony-forming cells increases angiogenesis via the CXCR4 pathway

Thrombosis and Haemostasis
2017-11 | Journal article
Part of ISSN: 0340-6245
Contributors: Peter Dorfmüller; Coralie Guerin; Ivan Bieche; Cécile Badoual; Elisa Boscolo; Marianne Kambouchner; Aurélie Cazes; Olaf Mercier; Marc Humbert; Pascale Gaussem et al.
Source: Self-asserted source
Elisa Boscolo via Crossref Metadata Search

EGFL6 Regulates the Asymmetric Division, Maintenance, and Metastasis of ALDH + Ovarian Cancer Cells

Cancer Research
2016-10 | Journal article
Part of ISSN: 0008-5472
Contributors: Shoumei Bai; Patrick Ingram; Yu-Chih Chen; Ning Deng; Alex Pearson; Yashar S. Niknafs; Patrick O'Hayer; Yun Wang; Zhong-Yin Zhang; Elisa Boscolo et al.
Source: Self-asserted source
Elisa Boscolo via Crossref Metadata Search

Rapamycin improves TIE2-mutated venous malformation in murine model and human subjects

Journal of Clinical Investigation
2015-08-10 | Journal article
Part of ISSN: 0021-9738
Contributors: Elisa Boscolo; Nisha Limaye; Lan Huang; Kyu-Tae Kang; Julie Soblet; Melanie Uebelhoer; Antonella Mendola; Marjut Natynki; Emmanuel Seront; Sophie Dupont et al.
Source: Self-asserted source
Elisa Boscolo via Crossref Metadata Search

0260 : Endoglin in adhesion between endothelial and mural cells

Archives of Cardiovascular Diseases Supplements
2015-04 | Journal article
Part of ISSN: 1878-6480
Contributors: Elisa Rossi; David Smadja; Elisa Boscolo; Carmen Langa; Miguel A. Arevalo; Miguel Pericacho; Alexandre Kauskot; Luisa M. Botella; Pascale Gaussem; Joyce Bischoff et al.
Source: Self-asserted source
Elisa Boscolo via Crossref Metadata Search

AKT hyper-phosphorylation associated with PI3K mutations in lymphatic endothelial cells from a patient with lymphatic malformation

Angiogenesis
2014-11 | Journal article
Part of ISSN: 0969-6970
Contributors: Elisa Boscolo; Silvia Coma; Valerie L. Luks; Arin K. Greene; Michael Klagsbrun; Matthew L. Warman; Joyce Bischoff
Source: Self-asserted source
Elisa Boscolo via Crossref Metadata Search

Cooperation between human fibrocytes and endothelial progenitor cells increases angiogenesis via CXCR4 pathway

Revue des Maladies Respiratoires
2014-09 | Journal article
Part of ISSN: 0761-8425
Contributors: D.M. Smadja; P. Dorfmüller; I. Bieche; E. Boscolo; M. Kambouchner; A. Cazes; O. Mercier; M. Humbert; P. Gaussem; J. Bischoff et al.
Source: Self-asserted source
Elisa Boscolo via Crossref Metadata Search

Propranolol targets the contractility of infantile haemangioma-derived pericytes

British Journal of Dermatology
2014-08 | Journal article
Part of ISSN: 0007-0963
Contributors: D. Lee; E. Boscolo; J.T. Durham; J.B. Mulliken; I.M. Herman; J. Bischoff
Source: Self-asserted source
Elisa Boscolo via Crossref Metadata Search

α6-Integrin Is Required for the Adhesion and Vasculogenic Potential of Hemangioma Stem Cells

STEM CELLS
2014-02 | Journal article
Part of ISSN: 1066-5099
Contributors: David M. Smadja; Coralie L. Guerin; Elisa Boscolo; Ivan Bieche; John B. Mulliken; Joyce Bischoff
Source: Self-asserted source
Elisa Boscolo via Crossref Metadata Search

Pericytes From Infantile Hemangioma Display Proangiogenic Properties and Dysregulated Angiopoietin-1

Arteriosclerosis, Thrombosis, and Vascular Biology
2013-03 | Journal article
Part of ISSN: 1079-5642
Contributors: Elisa Boscolo; John B. Mulliken; Joyce Bischoff
Source: Self-asserted source
Elisa Boscolo via Crossref Metadata Search

SOCS3 is an endogenous inhibitor of pathologic angiogenesis

Blood
2012-07 | Journal article
Part of ISSN: 0006-4971
Contributors: A. Stahl; J.-S. Joyal; J. Chen; P. Sapieha; A. M. Juan; C. J. Hatton; D. T. Pei; C. G. Hurst; M. R. Seaward; N. M. Krah et al.
Source: Self-asserted source
Elisa Boscolo via Crossref Metadata Search

Expression of HES and HEY genes in infantile hemangiomas

Vascular Cell
2011 | Journal article
Part of ISSN: 2045-824X
Contributors: Omotinuwe Adepoju; Alvin Wong; Alex Kitajewski; Karen Tong; Elisa Boscolo; Joyce Bischoff; Jan Kitajewski; June K Wu
Source: Self-asserted source
Elisa Boscolo via Crossref Metadata Search

Rapamycin Suppresses Self-Renewal and Vasculogenic Potential of Stem Cells Isolated from Infantile Hemangioma

Journal of Investigative Dermatology
2011 | Journal article
Part of ISSN: 0022-202X
Contributors: Shoshana Greenberger; Siming Yuan; Logan A. Walsh; Elisa Boscolo; Kyu-Tae Kang; Benjamin Matthews; John B. Mulliken; Joyce Bischoff
Source: Self-asserted source
Elisa Boscolo via Crossref Metadata Search

VEGFR-1 Mediates Endothelial Differentiation and Formation of Blood Vessels in a Murine Model of Infantile Hemangioma

The American Journal of Pathology
2011-11 | Journal article
Part of ISSN: 0002-9440
Contributors: Elisa Boscolo; John B. Mulliken; Joyce Bischoff
Source: Self-asserted source
Elisa Boscolo via Crossref Metadata Search

JAGGED1 Signaling Regulates Hemangioma Stem Cell–to–Pericyte/Vascular Smooth Muscle Cell Differentiation

Arteriosclerosis, Thrombosis, and Vascular Biology
2011-10 | Journal article
Part of ISSN: 1079-5642
Contributors: Elisa Boscolo; Camille L. Stewart; Shoshana Greenberger; June K. Wu; Jennifer T. Durham; Ira M. Herman; John B. Mulliken; Jan Kitajewski; Joyce Bischoff
Source: Self-asserted source
Elisa Boscolo via Crossref Metadata Search

Targeting NF-κB in infantile hemangioma-derived stem cells reduces VEGF-A expression

Angiogenesis
2010-09 | Journal article
Part of ISSN: 0969-6970
Contributors: Shoshana Greenberger; Irit Adini; Elisa Boscolo; John B. Mulliken; Joyce Bischoff
Source: Self-asserted source
Elisa Boscolo via Crossref Metadata Search

11: HEMANGIOMA STEM CELLS CAN DIFFERENTIATE INTO PERICYTES IN VITRO AND IN VIVO

Plastic and Reconstructive Surgery
2010-06 | Journal article
Part of ISSN: 0032-1052
Contributors: CL Stewart; E Boscolo; JB Mulliken; J Bischoff
Source: Self-asserted source
Elisa Boscolo via Crossref Metadata Search

Corticosteroid Suppression of VEGF-A in Infantile Hemangioma-Derived Stem Cells

New England Journal of Medicine
2010-03 | Journal article
Part of ISSN: 0028-4793
Contributors: Shoshana Greenberger; Elisa Boscolo; Irit Adini; John B. Mulliken; Joyce Bischoff
Source: Self-asserted source
Elisa Boscolo via Crossref Metadata Search

A switch in Notch gene expression parallels stem cell to endothelial transition in infantile hemangioma

Angiogenesis
2010-01 | Journal article
Part of ISSN: 0969-6970
Contributors: June K. Wu; Omotinuwe Adepoju; Dinuka De Silva; Keith Baribault; Elisa Boscolo; Joyce Bischoff; Jan Kitajewski
Source: Self-asserted source
Elisa Boscolo via Crossref Metadata Search

Vasculogenesis in infantile hemangioma

Angiogenesis
2009-05-10 | Journal article
Part of ISSN: 0969-6970
Contributors: Elisa Boscolo; Joyce Bischoff
Source: Self-asserted source
Elisa Boscolo via Crossref Metadata Search

Suppressed NFAT-dependent VEGFR1 expression and constitutive VEGFR2 signaling in infantile hemangioma

Nature Medicine
2008-10 | Journal article
Part of ISSN: 1078-8956
Contributors: Masatoshi Jinnin; Damian Medici; Lucy Park; Nisha Limaye; Yanqiu Liu; Elisa Boscolo; Joyce Bischoff; Miikka Vikkula; Eileen Boye; Bjorn R Olsen
Source: Self-asserted source
Elisa Boscolo via Crossref Metadata Search

Multipotential stem cells recapitulate human infantile hemangioma in immunodeficient mice

Journal of Clinical Investigation
2008-06-01 | Journal article
Part of ISSN: 0021-9738
Contributors: Zia A. Khan; Elisa Boscolo; Arnaud Picard; Sarah Psutka; Juan M. Melero-Martin; Tatianna C. Bartch; John B. Mulliken; Joyce Bischoff
Source: Self-asserted source
Elisa Boscolo via Crossref Metadata Search

IGF-2 and FLT-1/VEGF-R1 mRNA Levels Reveal Distinctions and Similarities Between Congenital and Common Infantile Hemangioma

Pediatric Research
2008-03 | Journal article
Part of ISSN: 0031-3998
Contributors: Arnaud Picard; Elisa Boscolo; Zia A Khan; Tatianna C Bartch; John B Mulliken; Marie Paule Vazquez; Joyce Bischoff
Source: Self-asserted source
Elisa Boscolo via Crossref Metadata Search

β amyloid angiogenic activity in vitro and in vivo

International Journal of Molecular Medicine
2007-04-01 | Journal article
Part of ISSN: 1107-3756
Contributors: Elisa Boscolo; Marcella Folin; Beatrice Nico; Claudio Grandi; Domenica Mangieri; Vito Longo; Renato Scienza; Paolo Zampieri; Maria Conconi; Pier Parnigotto et al.
Source: Self-asserted source
Elisa Boscolo via Crossref Metadata Search

Endothelial cells from human cerebral aneurysm and arteriovenous malformation release ET-1 in response to vessel rupture

International Journal of Molecular Medicine
2006-11-01 | Journal article
Part of ISSN: 1107-3756
Contributors: Elisa Boscolo; Giacomo Pavesi; Paolo Zampieri; Maria Conconi; Chiara Calore; Renato Scienza; Pier Parnigotto; Marcella Folin
Source: Self-asserted source
Elisa Boscolo via Crossref Metadata Search

In vitro culture of rat neuromicrovascular endothelial cells on polymeric scaffolds

Journal of Biomedical Materials Research
2004 | Journal article
Part of ISSN: 0021-9304
Contributors: Maria Teresa Conconi; Silvano Lora; Silvia Baiguera; Elisa Boscolo; Marcella Folin; Renato Scienza; Piera Rebuffat; Pier Paolo Parnigotto; Gastone Giovanni Nussdorfer
Source: Self-asserted source
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Peer review (1 review for 1 publication/grant)

Review activity for Angiogenesis. (1)