Personal information

extracellular vesicles, mesenchymal cells, microRNAs, kidney injury, tissue regeneration, kidney tubuloids
Brazil

Activities

Employment (1)

Universidade Federal do Rio de Janeiro: Rio de Janeiro, RJ, BR

2015-02-23 to present | Associate Professor (Carlos Chagas Filho Biophysics Institute)
Employment
Source: Self-asserted source
Rafael Soares Lindoso

Education and qualifications (5)

Utrecht University: Utrecht, Utrecht, NL

2019-06-01 to present | Post-Doc (Pharmacology Department)
Education
Source: Self-asserted source
Rafael Soares Lindoso

Università degli Studi di Torino: Torino, Piemonte, IT

2013-03-15 to 2015-01-17 | Post-Doc (Department of Medical Science )
Education
Source: Self-asserted source
Rafael Soares Lindoso

Universidade Federal do Rio de Janeiro: Rio de Janeiro, RJ, BR

2009-03-09 to 2013-03-10 | Ph.D. (Carlos Chagas Filho Biophysics Institute)
Education
Source: Self-asserted source
Rafael Soares Lindoso

Universidade Federal do Rio de Janeiro: Rio de Janeiro, RJ, BR

2007-07-08 to 2009-02-12 | Master (Carlos Chagas Filho Biophysics Institute)
Education
Source: Self-asserted source
Rafael Soares Lindoso

Universidade Federal do Estado do Rio de Janeiro: Rio de Janeiro, RJ, BR

2004-03-08 to 2007-06-30 | Graduation (Biophysics)
Education
Source: Self-asserted source
Rafael Soares Lindoso

Professional activities (1)

International Society of Extracellular Vesicles: Mount Royal, NEW JERSEY, US

2013-04-02 to present
Membership
Source: Self-asserted source
Rafael Soares Lindoso

Funding (5)

Cellular and molecular bases of solid tumor progression: impact, biomarkers and strategies for the development of anticancer therapies.

Grant
Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro (Rio de Janeiro, BR)
Source: Self-asserted source
Rafael Soares Lindoso

Interdisciplinary evaluation of the mechanisms involved in cardio-renal syndrome and identification of markers in diabetic disease.

Grant
Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro (Rio de Janeiro, BR)
Source: Self-asserted source
Rafael Soares Lindoso

miRNA profile transported by extracellular vesicles derived from adipose mesenchymal submitted to hypoxia and their effects in renal regeneration.

Grant
Conselho Nacional de Desenvolvimento Científico e Tecnológico (Brasilia, BR)
Source: Self-asserted source
Rafael Soares Lindoso

Modulation in miRNA profile transferred by extracellular vesicles derive from adipose mesenchymal cells under hypoxia

Grant
Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro (Rio de Janeiro, BR)
Source: Self-asserted source
Rafael Soares Lindoso

Preclinical studies to understand the chronic kidney injury mechanisms associated with aging: possible therapeutic and diagnostic strategies.

Grant
Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro (Rio de Janeiro, BR)
Source: Self-asserted source
Rafael Soares Lindoso

Works (25)

Aspirin Affects MDA-MB-231 Vesicle Production and Their Capacity to Induce Fibroblasts towards a Pro-Invasive State

International Journal of Molecular Sciences
2023-07-27 | Journal article
Contributors: Rafaela de Assiz Louback; Karina Martins-Cardoso; Luzineide W. Tinoco; Federica Collino; Ana Paula D. N. de Barros; Anneliese Fortuna-Costa; Robson Q. Monteiro; Maria Isabel Doria Rossi; Rafael Soares Lindoso
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Crossref
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Overexpression of mir-135b and mir-210 in mesenchymal stromal cells for the enrichment of extracellular vesicles with angiogenic factors

PLOS ONE
2022-08-16 | Journal article
Contributors: Juliana Maíra Freitas Vieira; Gianpaolo Papaccio; Laura Nicoleti Zamproni; Camila H. C. Wendt; Kildare Rocha de Miranda; Rafael Soares Lindoso; Sang Won Han
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Crossref

Early Effects of Extracellular Vesicles Secreted by Adipose Tissue Mesenchymal Cells in Renal Ischemia Followed by Reperfusion: Mechanisms Rely on a Decrease in Mitochondrial Anion Superoxide Production

International Journal of Molecular Sciences
2022-03-08 | Journal article
Contributors: Jarlene A. Lopes; Federica Collino; Clara Rodrigues-Ferreira; Luzia da Silva Sampaio; Glória Costa-Sarmento; Camila H. C. Wendt; Fernando P. Almeida; Kildare R. Miranda; Tais H. Kasai-Brunswick; Rafael S. Lindoso et al.
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Crossref
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Differentiated kidney tubular cell-derived extracellular vesicles enhance maturation of tubuloids

2022-02-09 | Preprint
Contributors: Rafael Soares Lindoso; Fjodor A Yousef Yengej; Franziska Voellmy; Maarten Altelaar; Estela Mancheño Juncosa; Theano Tsikari; Carola M.E. Ammerlaan; Bas W.M. Van Balkom; Maarten B Rookmaaker; Marianne C Verhaar et al.
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Crossref

Early Effects of Extracellular Vesicles Secreted by Adipose Tissue Mesenchymal Cells in Renal Ischemia Followed by Reperfusion: Mechanisms Rely on the Restoration of the Redox Tissular Environment

2022-02-03 | Preprint
Contributors: Jarlene A Lopes; Federica Collino; Clara Rodrigues-Ferreira; Luzia da Silva Sampaio; Glória Costa-Sarmento; Camila H.C. Wendt; Fernando P. Almeida; Kildare R. Miranda; Tais H. Kasai-Brunswick; Rafael S. Lindoso et al.
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Crossref
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Extracellular Vesicles as a Therapeutic Tool for Kidney Disease: Current Advances and Perspectives

International Journal of Molecular Sciences
2021-05-28 | Journal article
Contributors: Raphael Rodrigues Corrêa; Estela Mancheño Juncosa; Rosalinde Masereeuw; Rafael Soares Lindoso
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Crossref
grade
Preferred source (of 2)‎

Type 2 diabetes mellitus alters cardiac mitochondrial content and function in a non-obese mice model

Anais da Academia Brasileira de Ciências
2020 | Journal article
Contributors: AINHOA R. DE YURRE; EDUARDA G.L. MARTINS; MICAELA LOPEZ-ALARCON; BRUNO CABRAL; NARENDRA VERA; JARLENE A. LOPES; ANTONIO GALINA; CHRISTINA M. TAKIYA; RAFAEL S. LINDOSO; ADALBERTO VIEYRA et al.
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Crossref

Human Wharton’s Jelly Mesenchymal Stem Cells Protect Neural Cells from Oxidative Stress Through Paracrine Mechanisms

Future Science OA
2020-10 | Journal article
Contributors: Teresa Puig-Pijuan; Mariana A de Godoy; Luiza Rachel Pinheiro Carvalho; Victor Bodart-Santos; Rafael Soares Lindoso; Pedro Moreno Pimentel-Coelho; Rosalia Mendez-Otero
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Intrinsic and Extrinsic Modulators of the Epithelial to Mesenchymal Transition: Driving the Fate of Tumor Microenvironment

Frontiers in Oncology
2020-07-24 | Journal article
Part of ISSN: 2234-943X
Source: Self-asserted source
Rafael Soares Lindoso

Acute Myocardial Infarction Reduces Respiration in Rat Cardiac Fibers, despite Adipose Tissue Mesenchymal Stromal Cell Transplant.

Stem cells international
2020-06-20 | Journal article
Source: Self-asserted source
Rafael Soares Lindoso

Extracellular Vesicles Derived from Induced Pluripotent Stem Cells Promote Renoprotection in Acute Kidney Injury Model.

Cells
2020-02-17 | Journal article
Source: Self-asserted source
Rafael Soares Lindoso

Adipose Mesenchymal Cells-Derived EVs Alleviate DOCA-Salt-Induced Hypertension by Promoting Cardio-Renal Protection.

Molecular therapy. Methods & clinical development
2019-11-15 | Journal article
Source: Self-asserted source
Rafael Soares Lindoso

Proteomics in the World of Induced Pluripotent Stem Cells.

Cells
2019-07-11 | Journal article
Source: Self-asserted source
Rafael Soares Lindoso
grade
Preferred source (of 2)‎

Adipose-Derived Mesenchymal Stromal Cells Under Hypoxia: Changes in Extracellular Vesicles Secretion and Improvement of Renal Recovery after Ischemic Injury

Cellular Physiology and Biochemistry
2019-05-18 | Journal article
Part of ISSN: 1015-8987
Part of ISSN: 1421-9778
Source: Self-asserted source
Rafael Soares Lindoso

Extracellular vesicles as regulators of tumor fate: crosstalk among cancer stem cells, tumor cells and mesenchymal stem cells.

Stem cell investigation
2017 | Journal article
Contributors: Lindoso RS; Collino F; Vieyra A
Source: Self-asserted source
Rafael Soares Lindoso via Europe PubMed Central

Renal Regenerative Potential of Different Extracellular Vesicle Populations Derived from Bone Marrow Mesenchymal Stromal Cells.

Tissue engineering. Part A
2017-11 | Journal article
Contributors: Bruno S; Tapparo M; Collino F; Chiabotto G; Deregibus MC; Soares Lindoso R; Neri F; Kholia S; Giunti S; Wen S et al.
Source: Self-asserted source
Rafael Soares Lindoso via Europe PubMed Central

Exosome and Microvesicle-Enriched Fractions Isolated from Mesenchymal Stem Cells by Gradient Separation Showed Different Molecular Signatures and Functions on Renal Tubular Epithelial Cells.

Stem cell reviews
2017-04 | Journal article
Contributors: Collino F; Pomatto M; Bruno S; Lindoso RS; Tapparo M; Sicheng W; Quesenberry P; Camussi G
Source: Self-asserted source
Rafael Soares Lindoso via Europe PubMed Central

Proteomics of cell-cell interactions in health and disease.

Proteomics
2016-01 | Journal article
Contributors: Lindoso RS; Sandim V; Collino F; Carvalho AB; Dias J; da Costa MR; Zingali RB; Vieyra A
Source: Self-asserted source
Rafael Soares Lindoso via Europe PubMed Central

Extracellular vesicles derived from renal cancer stem cells induce a pro-tumorigenic phenotype in mesenchymal stromal cells.

Oncotarget
2015-04 | Journal article
Contributors: Lindoso RS; Collino F; Camussi G
Source: Self-asserted source
Rafael Soares Lindoso via Europe PubMed Central

miRNA Expression in Mesenchymal Stem Cells.

Current Pathobiology Reports
2014-09 | Journal article
Source: Self-asserted source
Rafael Soares Lindoso

Extracellular vesicles released from mesenchymal stromal cells modulate miRNA in renal tubular cells and inhibit ATP depletion injury.

Stem cells and development
2014-08 | Journal article
Contributors: Lindoso RS; Collino F; Bruno S; Araujo DS; Sant'Anna JF; Tetta C; Provero P; Quesenberry PJ; Vieyra A; Einicker-Lamas M et al.
Source: Self-asserted source
Rafael Soares Lindoso via Europe PubMed Central

Mechanisms of kidney repair by human mesenchymal stromal cells after ischemia: a comprehensive view using label-free MS(E).

Proteomics
2014-06 | Journal article
Contributors: da Costa MR; Pizzatti L; Lindoso RS; Sant'Anna JF; DuRocher B; Abdelhay E; Vieyra A
Source: Self-asserted source
Rafael Soares Lindoso via Europe PubMed Central

Paracrine interaction between bone marrow-derived stem cells and renal epithelial cells.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
2011 | Journal article
Contributors: Lindoso RS; Araujo DS; Adão-Novaes J; Mariante RM; Verdoorn KS; Fragel-Madeira L; Caruso-Neves C; Linden R; Vieyra A; Einicker-Lamas M
Source: Self-asserted source
Rafael Soares Lindoso via Europe PubMed Central

Bone marrow mononuclear cells shift bioactive lipid pattern in injured kidney towards tissue repair in rats with unilateral ureteral obstruction.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
2010-12 | Journal article
Contributors: Verdoorn KS; Lindoso RS; Lowe J; Lara LS; Vieyra A; Einicker-Lamas M
Source: Self-asserted source
Rafael Soares Lindoso via Europe PubMed Central

Renal recovery after injury: the role of Pax-2.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
2009-09 | Journal article
Contributors: Lindoso RS; Verdoorn KS; Einicker-Lamas M
Source: Self-asserted source
Rafael Soares Lindoso via Europe PubMed Central

Peer review (1 review for 1 publication/grant)

Review activity for Stem cell reviews. (1)