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Employment (11)

University of Florida: FL, FL, US

2021 to present | Professor (Pediatrics)
Employment
Source: Self-asserted source
Shannon Boye

University of Florida: FL, FL, US

2020 to present | Associate Chief, Division of Cellular and Molecular Therapy (Pediatrics)
Employment
Source: Self-asserted source
Shannon Boye

Atsena Therapeutics: Durham, NC, US

2020 to present | Founder, Director, Acting CSO
Employment
Source: Self-asserted source
Shannon Boye

University of Florida: FL, FL, US

2020 to 2021 | Associate Professor (Pediatrics)
Employment
Source: Self-asserted source
Shannon Boye

University of Florida: FL, FL, US

2017 to 2020 | Associate Professor (Ophthalmology)
Employment
Source: Self-asserted source
Shannon Boye

University of Florida: FL, FL, US

2012 to 2017 | Assistant Professor (Ophthalmology)
Employment
Source: Self-asserted source
Shannon Boye

University of Florida: FL, FL, US

2008 to 2012 | Research Assistant Professor (Opthalmology)
Employment
Source: Self-asserted source
Shannon Boye

University of Florida: FL, FL, US

2006 to 2008 | Postdoctoral Fellow (Ophthalmology)
Employment
Source: Self-asserted source
Shannon Boye

University of Florida: FL, FL, US

2001 to 2006 | Graduate Research Fellow (Neuroscience)
Employment
Source: Self-asserted source
Shannon Boye

Space and Naval Warfare Systems Command: San Diego, California, US

2002 to 2002 | Research Assistant
Employment
Source: Self-asserted source
Shannon Boye

University of Florida Whitney Laboratory for Marine Bioscience: Saint Augustine, FL, US

2000 to 2000 (REU Intern)
Employment
Source: Self-asserted source
Shannon Boye

Education and qualifications (1)

University of Florida: Gainesville, Florida, US

2001 to 2006 | Ph.D. in Neuroscience
Education
Source: Self-asserted source
Shannon Boye

Works (50 of 68)

Items per page:
Page 1 of 2

Gene Therapy in <i>Opn1mw<sup>-/-</sup>/Opn1sw<sup>-/-</sup></i> Mice and Implications for Blue Cone Monochromacy Patients with Deletion Mutations.

Human gene therapy
2022-05 | Journal article
Contributors: Ma X; Sechrest ER; Fajardo D; Zhu P; Dyka F; Wang Y; Lobanova E; Boye SE; Baehr W; Deng WT
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

Safety and improved efficacy signals following gene therapy in childhood blindness caused by <i>GUCY2D</i> mutations.

iScience
2021-04 | Journal article
Contributors: Jacobson SG; Cideciyan AV; Ho AC; Peshenko IV; Garafalo AV; Roman AJ; Sumaroka A; Wu V; Krishnan AK; Sheplock R et al.
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

Effects of Altering HSPG Binding and Capsid Hydrophilicity on Retinal Transduction by AAV.

Journal of virology
2021-03 | Journal article
Contributors: Crosson SM; Bennett A; Fajardo D; Peterson JJ; Zhang H; Li W; Leahy MT; Jennings CK; Boyd RF; Boye SL et al.
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

Current Clinical Applications of In Vivo Gene Therapy with AAVs.

Molecular therapy : the journal of the American Society of Gene Therapy
2020-12 | Journal article
Contributors: Mendell JR; Al-Zaidy SA; Rodino-Klapac LR; Goodspeed K; Gray SJ; Kay CN; Boye SL; Boye SE; George LA; Salabarria S et al.
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

Site-specific modifications to AAV8 capsid yields enhanced brain transduction in the neonatal MPS IIIB mouse.

Gene therapy
2020-11 | Journal article
Contributors: Gilkes JA; Judkins BL; Herrera BN; Mandel RJ; Boye SL; Boye SE; Srivastava A; Heldermon CD
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

Identifying Treatments for Taste and Smell Disorders: Gaps and Opportunities.

Chemical senses
2020-10 | Journal article
Contributors: Mainland JD; Barlow LA; Munger SD; Millar SE; Vergara MN; Jiang P; Schwob JE; Goldstein BJ; Boye SE; Martens JR et al.
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

SARM1 depletion rescues NMNAT1-dependent photoreceptor cell death and retinal degeneration.

eLife
2020-10 | Journal article
Contributors: Sasaki Y; Kakita H; Kubota S; Sene A; Lee TJ; Ban N; Dong Z; Lin JB; Boye SL; DiAntonio A et al.
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

SARM1 depletion rescues NMNAT1 dependent photoreceptor cell death and retinal degeneration

2020-05 | Preprint
Contributors: Sasaki Y; Kakita H; Kubota S; Sene A; Lee TJ; Ban N; Dong Z; Lin JB; Boye SL; DiAntonio A et al.
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

Adeno-Associated Virus D-Sequence-Mediated Suppression of Expression of a Human Major Histocompatibility Class II Gene: Implications in the Development of Adeno-Associated Virus Vectors for Modulating Humoral Immune Response.

Human gene therapy
2020-04 | Journal article
Contributors: Kwon HJ; Qing K; Ponnazhagan S; Wang XS; Markusic DM; Gupte S; Boye SE; Srivastava A
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

Novel AAV44.9-Based Vectors Display Exceptional Characteristics for Retinal Gene Therapy.

Molecular therapy : the journal of the American Society of Gene Therapy
2020-04 | Journal article
Contributors: Boye SL; Choudhury S; Crosson S; Di Pasquale G; Afione S; Mellen R; Makal V; Calabro KR; Fajardo D; Peterson J et al.
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

Utilizing minimally purified secreted rAAV for rapid and cost-effective manipulation of gene expression in the CNS.

Molecular neurodegeneration
2020-03 | Journal article
Contributors: Goodwin MS; Croft CL; Futch HS; Ryu D; Ceballos-Diaz C; Liu X; Paterno G; Mejia C; Deng D; Menezes K et al.
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

A Novel Mouse Model of <i>MYO7A</i> USH1B Reveals Auditory and Visual System Haploinsufficiencies.

Frontiers in neuroscience
2019-11 | Journal article
Contributors: Calabro KR; Boye SL; Choudhury S; Fajardo D; Peterson JJ; Li W; Crosson SM; Kim MJ; Ding D; Salvi R et al.
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

SubILM Injection of AAV for Gene Delivery to the Retina.

Methods in molecular biology (Clifton, N.J.)
2019-01 | Journal article
Contributors: Gamlin PD; Alexander JJ; Boye SL; Witherspoon CD; Boye SE
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

Somatic Gene Editing of <i>GUCY2D</i> by AAV-CRISPR/Cas9 Alters Retinal Structure and Function in Mouse and Macaque.

Human gene therapy
2018-12 | Journal article
Contributors: McCullough KT; Boye SL; Fajardo D; Calabro K; Peterson JJ; Strang CE; Chakraborty D; Gloskowski S; Haskett S; Samuelsson S et al.
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

A Drug-Tunable Gene Therapy for Broad-Spectrum Protection against Retinal Degeneration.

Molecular therapy : the journal of the American Society of Gene Therapy
2018-07 | Journal article
Contributors: Santiago CP; Keuthan CJ; Boye SL; Boye SE; Imam AA; Ash JD
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

A drug-tunable gene therapy for broad-spectrum protection against retinal degeneration

2018-03 | Preprint
Contributors: Santiago CP; Keuthan CJ; Boye SL; Boye SE; Imam AA; Ash JD
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

Rationally Engineered AAV Capsids Improve Transduction and Volumetric Spread in the CNS.

Molecular therapy. Nucleic acids
2017-06 | Journal article
Contributors: Kanaan NM; Sellnow RC; Boye SL; Coberly B; Bennett A; Agbandje-McKenna M; Sortwell CE; Hauswirth WW; Boye SE; Manfredsson FP
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

Optimization of Retinal Gene Therapy for X-Linked Retinitis Pigmentosa Due to RPGR Mutations.

Molecular therapy : the journal of the American Society of Gene Therapy
2017-05 | Journal article
Contributors: Beltran WA; Cideciyan AV; Boye SE; Ye GJ; Iwabe S; Dufour VL; Marinho LF; Swider M; Kosyk MS; Sha J et al.
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

The GCaMP-R Family of Genetically Encoded Ratiometric Calcium Indicators.

ACS chemical biology
2017-03 | Journal article
Contributors: Cho JH; Swanson CJ; Chen J; Li A; Lippert LG; Boye SE; Rose K; Sivaramakrishnan S; Chuong CM; Chow RH
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

Defining Outcomes for Clinical Trials of Leber Congenital Amaurosis Caused by GUCY2D Mutations.

American journal of ophthalmology
2017-02 | Journal article
Contributors: Jacobson SG; Cideciyan AV; Sumaroka A; Roman AJ; Charng J; Lu M; Choudhury S; Schwartz SB; Heon E; Fishman GA et al.
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

Increased vulnerability of photoreceptors to aberrant splicing highlight the utility of AON-based therapy for <i>CEP290</i>-LCA.

Stem cell investigation
2016-12 | Journal article
Contributors: Boye SE
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

Novel Methodology for Creating Macaque Retinas with Sortable Photoreceptors and Ganglion Cells.

Frontiers in neuroscience
2016-12 | Journal article
Contributors: Choudhury S; Strang CE; Alexander JJ; Scalabrino ML; Lynch Hill J; Kasuga DT; Witherspoon CD; Boye SL; Gamlin PD; Boye SE
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

Functional study of two biochemically unusual mutations in <i>GUCY2D</i> Leber congenital amaurosis expressed via adenoassociated virus vector in mouse retinas.

Molecular vision
2016-11 | Journal article
Contributors: Boye SL; Olshevskaya EV; Peshenko IV; McCullough KT; Boye SE; Dizhoor AM
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

NF1 Is a Direct G Protein Effector Essential for Opioid Signaling to Ras in the Striatum.

Current biology : CB
2016-10 | Journal article
Contributors: Xie K; Colgan LA; Dao MT; Muntean BS; Sutton LP; Orlandi C; Boye SL; Boye SE; Shih CC; Li Y et al.
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

Highly Efficient Delivery of Adeno-Associated Viral Vectors to the Primate Retina.

Human gene therapy
2016-08 | Journal article
Contributors: Boye SE; Alexander JJ; Witherspoon CD; Boye SL; Peterson JJ; Clark ME; Sandefer KJ; Girkin CA; Hauswirth WW; Gamlin PD
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

Photoreceptor-targeted gene delivery using intravitreally administered AAV vectors in dogs.

Gene therapy
2016-04 | Journal article
Contributors: Boyd RF; Sledge DG; Boye SL; Boye SE; Hauswirth WW; Komáromy AM; Petersen-Jones SM; Bartoe JT
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

Reduced retinal transduction and enhanced transgene-directed immunogenicity with intravitreal delivery of rAAV following posterior vitrectomy in dogs.

Gene therapy
2016-04 | Journal article
Contributors: Boyd RF; Boye SL; Conlon TJ; Erger KE; Sledge DG; Langohr IM; Hauswirth WW; Komáromy AM; Boye SE; Petersen-Jones SM et al.
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

Impact of Heparan Sulfate Binding on Transduction of Retina by Recombinant Adeno-Associated Virus Vectors.

Journal of virology
2016-03 | Journal article
Contributors: Boye SL; Bennett A; Scalabrino ML; McCullough KT; Van Vliet K; Choudhury S; Ruan Q; Peterson J; Agbandje-McKenna M; Boye SE
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

Targeting the Nrf2 Signaling Pathway in the Retina With a Gene-Delivered Secretable and Cell-Penetrating Peptide.

Investigative ophthalmology & visual science
2016-02 | Journal article
Contributors: Ildefonso CJ; Jaime H; Brown EE; Iwata RL; Ahmed CM; Massengill MT; Biswal MR; Boye SE; Hauswirth WW; Ash JD et al.
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

A Mini-review: Animal Models of GUCY2D Leber Congenital Amaurosis (LCA1).

Advances in experimental medicine and biology
2016-01 | Journal article
Contributors: Boye SE
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

Cone-Specific Promoters for Gene Therapy of Achromatopsia and Other Retinal Diseases.

Human gene therapy
2016-01 | Journal article
Contributors: Ye GJ; Budzynski E; Sonnentag P; Nork TM; Sheibani N; Gurel Z; Boye SL; Peterson JJ; Boye SE; Hauswirth WW et al.
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

Photoreceptor-targeted gene delivery using intravitreally administered AAV vectors in dogs.

Gene therapy
2015-10 | Journal article
Contributors: Boyd RF; Sledge DG; Boye SL; Boye SE; Hauswirth WW; Komáromy AM; Petersen-Jones SM; Bartoe JT
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

Systemic Vascular Transduction by Capsid Mutant Adeno-Associated Virus After Intravenous Injection.

Human gene therapy
2015-09 | Journal article
Contributors: Lipinski DM; Reid CA; Boye SL; Peterson JJ; Qi X; Boye SE; Boulton ME; Hauswirth WW
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

Gene Therapy Fully Restores Vision to the All-Cone Nrl(-/-) Gucy2e(-/-) Mouse Model of Leber Congenital Amaurosis-1.

Human gene therapy
2015-08 | Journal article
Contributors: Boye SL; Peterson JJ; Choudhury S; Min SH; Ruan Q; McCullough KT; Zhang Z; Olshevskaya EV; Peshenko IV; Hauswirth WW et al.
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

Intravitreal delivery of a novel AAV vector targets ON bipolar cells and restores visual function in a mouse model of complete congenital stationary night blindness.

Human molecular genetics
2015-08 | Journal article
Contributors: Scalabrino ML; Boye SL; Fransen KM; Noel JM; Dyka FM; Min SH; Ruan Q; De Leeuw CN; Simpson EM; Gregg RG et al.
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

Capsid Mutated Adeno-Associated Virus Delivered to the Anterior Chamber Results in Efficient Transduction of Trabecular Meshwork in Mouse and Rat.

PloS one
2015-06 | Journal article
Contributors: Bogner B; Boye SL; Min SH; Peterson JJ; Ruan Q; Zhang Z; Reitsamer HA; Hauswirth WW; Boye SE
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

Gene therapy with the caspase activation and recruitment domain reduces the ocular inflammatory response.

Molecular therapy : the journal of the American Society of Gene Therapy
2015-02 | Journal article
Contributors: Ildefonso CJ; Jaime H; Biswal MR; Boye SE; Li Q; Hauswirth WW; Lewin AS
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

Gene delivery of a viral anti-inflammatory protein to combat ocular inflammation.

Human gene therapy
2015-01 | Journal article
Contributors: Ildefonso CJ; Jaime H; Rahman MM; Li Q; Boye SE; Hauswirth WW; Lucas AR; McFadden G; Lewin AS
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

Targeted gene delivery to the enteric nervous system using AAV: a comparison across serotypes and capsid mutants.

Molecular therapy : the journal of the American Society of Gene Therapy
2015-01 | Journal article
Contributors: Benskey MJ; Kuhn NC; Galligan JJ; Garcia J; Boye SE; Hauswirth WW; Mueller C; Boye SL; Manfredsson FP
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

Leber congenital amaurosis caused by mutations in GUCY2D.

Cold Spring Harbor perspectives in medicine
2014-09 | Journal article
Contributors: Boye SE
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

Gene therapy: charting a future course--summary of a National Institutes of Health Workshop, April 12, 2013.

Human gene therapy
2014-06 | Journal article
Contributors: O'Reilly M; Federoff HJ; Fong Y; Kohn DB; Patterson AP; Ahmed N; Asokan A; Boye SE; Crystal RG; De Oliveira S et al.
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

Insights gained from gene therapy in animal models of retGC1 deficiency.

Frontiers in molecular neuroscience
2014-05 | Journal article
Contributors: Boye SE
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

Dual adeno-associated virus vectors result in efficient in vitro and in vivo expression of an oversized gene, MYO7A.

Human gene therapy methods
2014-04 | Journal article
Contributors: Dyka FM; Boye SL; Chiodo VA; Hauswirth WW; Boye SE
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

Natural history of cone disease in the murine model of Leber congenital amaurosis due to CEP290 mutation: determining the timing and expectation of therapy.

PloS one
2014-03 | Journal article
Contributors: Boye SE; Huang WC; Roman AJ; Sumaroka A; Boye SL; Ryals RC; Olivares MB; Ruan Q; Tucker BA; Stone EM et al.
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

Cone specific promoter for use in gene therapy of retinal degenerative diseases.

Advances in experimental medicine and biology
2014-01 | Journal article
Contributors: Dyka FM; Boye SL; Ryals RC; Chiodo VA; Boye SE; Hauswirth WW
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

Targeted CNS Delivery Using Human MiniPromoters and Demonstrated Compatibility with Adeno-Associated Viral Vectors.

Molecular therapy. Methods & clinical development
2014-01 | Journal article
Contributors: de Leeuw CN; Dyka FM; Boye SL; Laprise S; Zhou M; Chou AY; Borretta L; McInerny SC; Banks KG; Portales-Casamar E et al.
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

Retinal pigment epithelial detachment in ABCA4-associated Stargardt's disease.

Ophthalmic surgery, lasers & imaging retina
2013-07 | Journal article
Contributors: Cohen J; Bhullar S; Kasuga D; Boye S; Elhalis H; Kay CN
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

Targeting photoreceptors via intravitreal delivery using novel, capsid-mutated AAV vectors.

PloS one
2013-04 | Journal article
Contributors: Kay CN; Ryals RC; Aslanidi GV; Min SH; Ruan Q; Sun J; Dyka FM; Kasuga D; Ayala AE; Van Vliet K et al.
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

Preclinical potency and safety studies of an AAV2-mediated gene therapy vector for the treatment of MERTK associated retinitis pigmentosa.

Human gene therapy. Clinical development
2013-03 | Journal article
Contributors: Conlon TJ; Deng WT; Erger K; Cossette T; Pang JJ; Ryals R; Clément N; Cleaver B; McDoom I; Boye SE et al.
Source: Self-asserted source
Shannon Boye via Europe PubMed Central

RNAi-mediated gene suppression in a GCAP1(L151F) cone-rod dystrophy mouse model.

PloS one
2013-03 | Journal article
Contributors: Jiang L; Li TZ; Boye SE; Hauswirth WW; Frederick JM; Baehr W
Source: Self-asserted source
Shannon Boye via Europe PubMed Central
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Peer review (1 review for 1 publication/grant)

Review activity for Nature biomedical engineering. (1)