Personal information

Netherlands

Activities

Employment (3)

Leiden University Medical Center: Leiden, NL

2023-02-01 to present | Clinical Chemist in training (Department of Clinical Chemistry and Laboratory Medicine)
Employment
Source: Self-asserted source
T.L.J. van Osch

Sanquin Diagnostics: Amsterdam, Noord Holland, NL

2022-04-15 to 2023-01-31 | Scientist (Erythrocyte Serology Department)
Employment
Source: Self-asserted source
T.L.J. van Osch

Sanquin Research: Amsterdam, North Holland, NL

2018-04-01 to 2022-03-31 | PhD Student (Immunoglobulin Research)
Employment
Source: Self-asserted source
T.L.J. van Osch

Education and qualifications (2)

Wageningen University & Research: Wageningen, Gelderland, NL

2015 to 2018 | MSc Biology
Education
Source: Self-asserted source
T.L.J. van Osch

Wageningen University & Research: Wageningen, Gelderland, NL

2011 to 2014 | BSc Biology
Education
Source: Self-asserted source
T.L.J. van Osch

Works (10)

Impact of structural modifications of IgG antibodies on effector functions

Frontiers in Immunology
2024-01-08 | Journal article
Part of ISSN: 1664-3224
Contributors: Timon Damelang; Maximilian Brinkhaus; Thijs L. J. van Osch; Janine Schuurman; Aran F. Labrijn; Theo Rispens; Gestur Vidarsson
Source: Self-asserted source
T.L.J. van Osch

Complement activation drives antibody-mediated transfusion-related acute lung injury via macrophage trafficking and formation of NETs

Blood
2024-01-04 | Journal article
Contributors: Saskia van der Velden; Thijs L. J. van Osch; Amina Seghier; Arthur E. H. Bentlage; Juk Yee Mok; Dionne M. Geerdes; Wim J. E. van Esch; Richard B. Pouw; Mieke C. Brouwer; Ilse Jongerius et al.
Source: check_circle
Crossref

Phagocytosis of platelets opsonized with differently glycosylated anti-HLA hIgG1 by monocyte-derived macrophages

Platelets
2023-12-31 | Journal article
Contributors: Thijs L. J. van Osch; Juulke Steuten; Jan Nouta; Carolien A. M. Koeleman; Arthur E. H. Bentlage; Sebastiaan Heidt; Arend Mulder; Jan Voorberg; S. Marieke van Ham; Manfred Wuhrer et al.
Source: check_circle
Crossref

The BNT162b2 mRNA SARS-CoV-2 vaccine induces transient afucosylated IgG1 in naive but not in antigen-experienced vaccinees

eBioMedicine
2023-01 | Journal article
Contributors: Julie Van Coillie; Tamas Pongracz; Johann Rahmöller; Hung-Jen Chen; Chiara Elisabeth Geyer; Lonneke A. van Vught; Jana Sophia Buhre; Tonći Šuštić; Thijs Luc Junior van Osch; Maurice Steenhuis et al.
Source: check_circle
Crossref

Altered Fc glycosylation of anti‐HLA alloantibodies in hemato‐oncological patients receiving platelet transfusions

Journal of Thrombosis and Haemostasis
2022-12 | Journal article
Contributors: Thijs L.J. van Osch; Tamas Pongracz; Dionne M. Geerdes; Juk Yee Mok; Wim J.E. van Esch; Jan Voorberg; Rick Kapur; Leendert Porcelijn; Jean‐Louis H. Kerkhoffs; Pieter F. van der Meer et al.
Source: check_circle
Crossref

Fc galactosylation of anti-platelet human IgG1 alloantibodies enhances complement activation on platelets.

Haematologica
2022-10 | Journal article
Contributors: Van Osch TLJ; Oosterhoff JJ; Bentlage AEH; Nouta J; Koeleman CAM; Geerdes DM; Mok JY; Heidt S; Mulder A; Van Esch WJE et al.
Source: Self-asserted source
T.L.J. van Osch via Europe PubMed Central

Fc Galactosylation Promotes Hexamerization of Human IgG1, Leading to Enhanced Classical Complement Activation

The Journal of Immunology
2021-09-15 | Journal article
Contributors: Thijs L. J. van Osch; Jan Nouta; Ninotska I. L. Derksen; Gerard van Mierlo; C. Ellen van der Schoot; Manfred Wuhrer; Theo Rispens; Gestur Vidarsson
Source: check_circle
Crossref

Biological and structural characterization of murine TRALI antibody reveals increased Fc-mediated complement activation.

Blood advances
2020-08-01 | Journal article
Source: Self-asserted source
T.L.J. van Osch

Induction of Trained Innate Immunity in Human Monocytes by Bovine Milk and Milk-Derived Immunoglobulin G.

Nutrients
2018-09-27 | Journal article
Source: Self-asserted source
T.L.J. van Osch

BAFF augments IgA2 and IL-10 production by TLR7/8 stimulated total peripheral blood B cells.

European journal of immunology
2017-10-11 | Journal article
Source: Self-asserted source
T.L.J. van Osch