Estefania Nova-Lamperti (0000-0002-7673-0013)

Personal information

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Biography

EDUCATION

Post-Doctoral Fellowship Immunology, December 2014 – December 2016
Dr. Susan John’s Lab, Division of Immunology, Infection & Inflammatory Disease Division.
Supervisors Dr Susan John & Dr Behdad Afzali.

CONICYT Post-Doctoral Fellowship 2009.
Chilean Governament Post-Doctoral Fellowship Becas CHILE.

PhD in Immunology, October 2009 – October 2013
L.O.R.D Lab, Department of Experimental Immunobiology. Division of Transplantation Immunology and Mucosal Biology Research.
Supervisors Dr. Maria Hernandez Fuentes & Professor Giovanna Lombardi.

CONICYT PhD Scholarship 2009.
Chilean Governament PhD Scholarship Becas CHILE.

Professional Degree: Biochemist September 2009.

BSc in Biochemistry March 2003 – December 2007.
Universidad de Concepción, Concepción, Chile. Grade average: 6.1/7 ~ First

Secondary Education (~ A levels). March 1999 – December 2002
Colegio Concepción, Concepcion, Chile. Grade Average 6.9/7 ~ First

POSTS

Assistant Professor, May 2017 – Present
Department of Clinical Biochemistry & Immunology, Pharmacy Faculty, University of Concepcion
Victor Lamas 1290, Casilla 160-C, Concepción, CHILE.

Post Doctoral Fellow, December 2014 – December 2016
John’s Lab, Immunology, Infection & Inflammatory Disease Division, King’s College London
2nd floor Bermondsey Wing, Guy's Hospital.
Great Maze Pond, London, SE1 9RT. United Kingdom.

Flow Cytometry Manager, March 2013 – April 2017
Immunoregulation Lab, Transplantation Immunology & Mucosal Biology Division, King’s College London
5th floor Southwark Wing, Guy's Hospital.
Great Maze Pond, London, SE1 9RT. United Kingdom.

Flow Cytometry Research Assistant, December 2012 – March 2013
Flow cytometry laboratory, Biomedical Research Centre, Guy’s and St Thomas’ NHS Foundation Trust and King’s College London
15th floor Tower Wing, Guy's Hospital.
Great Maze Pond, London, SE1 9RT. United Kingdom.

Research Assistant, October 2012 – December 2012
L.O.R.D Lab, Transplantation Immunology & Mucosal Biology Division, King’s College London
5th floor Tower Wing, Guy's Hospital.
Great Maze Pond, London, SE1 9RT. United Kingdom

Post-graduate placement, January 2008 – August 2009
Laboratory of Clinic and Molecular Immunology, Faculty of Science, University of los Andes,
San Carlos de Apoquindo 2200, Las Condes, Santiago.

Activities

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UNIVERSIDAD DE CONCEPCION: CONCEPCION, VIII, CL

PROFESOR ASISTENTE (DEPARTAMENTO DE BIOQUIMICA CLINICA E INMUNOLOGIA)

Employment

Estefania Nova-Lamperti

https://orcid.org/0000-0002-7673-0013

Personal information

Biography

Activities

Employment (3)

UNIVERSIDAD DE CONCEPCION: CONCEPCION, VIII, CL

University of Concepción: Concepción, Bío-Bío, CL

Universidad de Concepción: Concepcion, VIII, CL

Education and qualifications (1)

King's College London: London, London, GB

Professional activities (2)

British Society for Immunology: London, GB

Asociación Chilena de Inmunología: Santiago, Metropolitana, CL

Funding (9)

Integrated multi-omic immune profiling of human RNA respiratory viruses: current and future pandemics

Preclinical Validation of Therapeutic Monoclonal Antibodies for the Treatment of Hantavirus Cardiopulmonary Syndrome

Covid-19 Genomics Network (c19-genonet)

Synthesis and Biological Activity of New Hybrid Chalcone and Benzodihydrofuran Analogues

The collateral effect of defense against COVID-19: Analysis of the inflammatory response and its association with potential lung damage in recovered patients with severe, moderate and asymptomatic COVID-19.

Study Of The Metabolic Reprograming Of Effector CD4+T Cells By Mitochondria Transfer In Oral Cancer And Its Effect Upon T Helper And T-dependent B Cell Responses

Study Of The Chemoattractant Mechanism Of Human Th2-like Tregs To Tomour Environments And How This Regulatory Subset Supports The Maintenance Of An Anti-inflammatory Milieu In Oral Squamous Cell Carcinoma

Study of the protective role of the lox-1/LOXIN interaction to prevent endothelial dysfunction and inflammation in a new zebrafish model with preclinical atherosclerosis

Regulation of Anti-inflammatory Cytokine Production in Cd4+ T Cells as Measured by Vitamin D in Normal Individuals and in Patients with Psoriasis

Works (41)

The Chilean COVID-19 Genomics Network Biorepository: A Resource for Multi-Omics Studies of COVID-19 and Long COVID in a Latin American Population

New Formulation of a Subunit Vaccine Candidate against <i>Lawsonia intracellularis</i> Increases Humoral and Cellular Immune Responses

Association between Acute Respiratory Distress Syndrome Due to COVID-19 and Long-Term Sleep and Circadian Sleep–Wake Disorders

Adenosine promoted angiogenesis mediated by the release of small extracellular vesicles from human endothelial progenitor cells

Bioactivity analysis of calcium silicate‐based sealers and repair cements on the phenotype and cytokine secretion profile of <scp>CD14</scp> <sup>+</sup> monocytes: An <i>ex vivo</i> study

<i>IFI27</i> transcription is an early predictor for COVID-19 outcomes, a multi-cohort observational study.

Identification of circulating microRNA profiles associated with pulmonary function and radiologic features in survivors of SARS-CoV-2-induced ARDS.

Analysis of Tumor-Infiltrating T-Cell Transcriptomes Reveal a Unique Genetic Signature across Different Types of Cancer

Loxin Reduced the Inflammatory Response in the Liver and the Aortic Fatty Streak Formation in Mice Fed with a High-Fat Diet

Impact of Obstructive Sleep Apnea (OSA) in COVID-19 Survivors, Symptoms Changes Between 4-Months and 1 Year After the COVID-19 Infection.

Sleep health and the circadian rest-activity pattern four months after COVID-19.

Secretome from Human Mesenchymal Stem Cells-Derived Endothelial Cells Promotes Wound Healing in a Type-2 Diabetes Mouse Model

Evaluation of the Immune Response Induced by CoronaVac 28-Day Schedule Vaccination in a Healthy Population Group.

Defective STAT5 Activation and Aberrant Expression of BCL6 in Naive CD4 T Cells Enhances Follicular Th Cell-like Differentiation in Patients with Granulomatosis with Polyangiitis.

Autocrine vitamin D signaling switches off pro-inflammatory programs of T<sub>H</sub>1 cells.

Augmented Expansion of Treg Cells From Healthy and Autoimmune Subjects <i>via</i> Adult Progenitor Cell Co-Culture.

Analysis of clinical symptoms, radiological changes and pulmonary function data 4 months after COVID-19.

Immunomodulation of T Helper Cells by Tumor Microenvironment in Oral Cancer Is Associated With CCR8 Expression and Rapid Membrane Vitamin D Signaling Pathway.

PD-L1 signaling on human memory CD4+ T cells induces a regulatory phenotype.

Undiagnosed sleep disorder breathing as a risk factor for critical COVID-19 and pulmonary consequences at the midterm follow-up.

Differential CD4 T Regulatory Cell Phenotype Induced by Andes Hantavirus Glycoprotein.

Development and validation of the first consensus gene-expression signature of operational tolerance in kidney transplantation, incorporating adjustment for immunosuppressive drug therapy.

Synthesis and Cytotoxic Analysis of Novel Myrtenyl Grafted Pseudo-Peptides Revealed Potential Candidates for Anticancer Therapy.

Rapid development of severe acute respiratory distress syndrome after abatacept treatment in a patient with rheumatoid arthritis.

Regulatory B cells: Development, phenotypes, functions, and role in transplantation.

Plasma from Patients with Rheumatoid Arthritis Reduces Nitric Oxide Synthesis and Induces Reactive Oxygen Species in A Cell-Based Biosensor.

Human retinoic acid-regulated CD161<sup>+</sup> regulatory T cells support wound repair in intestinal mucosa.

Expanded Regulatory T Cells Induce Alternatively Activated Monocytes With a Reduced Capacity to Expand T Helper-17 Cells.

Steroid regulation: An overlooked aspect of tolerance and chronic rejection in kidney transplantation.

Reduced TCR Signaling Contributes to Impaired Th17 Responses in Tolerant Kidney Transplant Recipients

An Atlas of Human Regulatory T Helper-like Cells Reveals Features of Th2-like Tregs that Support a Tumorigenic Environment

Increased CD40 Ligation and Reduced BCR Signalling Leads to Higher IL-10 Production in B Cells From Tolerant Kidney Transplant Patients.

Biomarkers of Tolerance in Kidney Transplantation: Are We Predicting Tolerance or Response to Immunosuppressive Treatment?

Mesenchymal Stem Cell-Derived Extracellular Vesicles Promote Angiogenesis: Potencial Clinical Application.

IL-10-produced by human transitional B-cells down-regulates CD86 expression on B-cells leading to inhibition of CD4+T-cell responses.

Impact of immunosuppressive drugs on the therapeutic efficacy of ex vivo expanded human regulatory T cells.

Regulatory T-cell therapy in the induction of transplant tolerance: the issue of subpopulations.

Thymic versus induced regulatory T cells - who regulates the regulators?

Mesenchymal stem cells generate a CD4+CD25+Foxp3+ regulatory T cell population during the differentiation process of Th1 and Th17 cells.

Opposing effect of mesenchymal stem cells on Th1 and Th17 cell polarization according to the state of CD4+ T cell activation.

Culture and characterization of mesenchymal stem cells from human gingival tissue.

Peer review (1 review for 1 publication/grant)