Personal information

Verified email domains

Activities

Employment (6)

University of Glasgow: Glasgow, GB

(Therapeutic Science Research)
Employment
Source: check_circle
University of Glasgow

University of Glasgow: Glasgow, GB

2024-01-08 to present | Group Leader (School of Cancer Sciences)
Employment
Source: Self-asserted source
Johan Vande Voorde

The Beatson Institute for Cancer Research: Glasgow, GB

2022-06-01 to 2024-01-07 | Associate Scientist (Sansom laboratory (colorectal cancer and wnt signalling))
Employment
Source: Self-asserted source
Johan Vande Voorde

Cancer Research UK Beatson Institute: Glasgow, GB

2018-10-20 to 2022-05-31 | Postdoctoral researcher (Sansom laboratory (colorectal cancer and wnt signalling))
Employment
Source: Self-asserted source
Johan Vande Voorde

Cancer Research UK Beatson Institute: Glasgow, Glasgow, GB

2015-01-01 to 2018-10-19 | Postdoctoral Researcher (Gottlieb laboratory (Tumour metabolism and Apoptosis))
Employment
Source: Self-asserted source
Johan Vande Voorde

KU Leuven: Leuven, BE

2014 to 2014 | Postdoctoral Researcher
Employment
Source: Self-asserted source
Johan Vande Voorde

Education and qualifications (2)

KU Leuven: Leuven, BE

2008 to 2013 | Phd Biomedical Sciences
Education
Source: Self-asserted source
Johan Vande Voorde

University of Amsterdam: Amsterdam, NL

2005 to 2007 | MSc Biological Sciences
Education
Source: Self-asserted source
Johan Vande Voorde

Works (31)

Spatial metabolomics to unravel cellular metabolism.

Nature reviews. Genetics
2025-01-28 | Journal article | Author
Contributors: Rafa Najumudeen; Johan Vande Voorde
Source: Self-asserted source
Johan Vande Voorde

Visualizing Cancer Heterogeneity at the Molecular and Cellular Levels: Lessons from Rosetta.

Cancer discovery
2025-01-01 | Journal article
Contributors: Richard Goodwin; Cancer Grand Challenges Rosetta Consortium; John Marshall; George Poulogiannis; Mariia Yuneva; Kevin Brindle; Zoltan Takats; Owen J. Sansom; Josephine Bunch; Simon T Barry et al.
Source: Self-asserted source
Johan Vande Voorde

Colibactin-driven colon cancer requires adhesin-mediated epithelial binding.

Nature
2024-11-06 | Journal article | Author
Contributors: Maude Jans; Magdalena Kołata; Blancke G; Aline D'Hondt; Claudia Gräf; Maarten Ciers; Sze M; Thiran A; Petta I; Andries V et al.
Source: Self-asserted source
Johan Vande Voorde

Absent expansion of AXIN2+ hepatocytes and altered physiology in Axin2CreERT2 mice challenges the role of pericentral hepatocytes in homeostatic liver regeneration

Journal of hepatology
2023 | Journal article
Part of ISSN: 0168-8278
Contributors: May, Stephanie; Müller, Miryam; Livingstone, Callum R; Skalka, George L; Walsh, Peter J; Nixon, Colin; Hedley, Ann; Shaw, Robin; Clark, William; Vande Voorde, Johan et al.
Source: Self-asserted source
Johan Vande Voorde

Hepatic glutamine synthetase controls N<sup>5</sup>-methylglutamine in homeostasis and cancer

Nature chemical biology
2023 | Journal article
Part of ISSN: 1552-4450
Contributors: Villar, Victor H; Allega, Maria Francesca; Deshmukh, Ruhi; Ackermann, Tobias; Nakasone, Mark A; Vande Voorde, Johan; Drake, Thomas M; Oetjen, Janina; Bloom, Algernon; Nixon, Colin et al.
Source: Self-asserted source
Johan Vande Voorde

Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target

2023 | Other
Contributors: Voorde, Johan Vande; Najumudeen, Arafath; Steven, Rory; Nikula, Chelsea; Dexter, Alex; Zeiger, Lucas; Elia, Efstathios; Nasif, Ammar; Gonzalez-Fernandez, Ariadna; Murta, Teresa et al.
Source: Self-asserted source
Johan Vande Voorde

Arginine dependency is a therapeutically exploitable vulnerability in chronic myeloid leukaemic stem cells.

EMBO reports
2023-07-25 | Journal article
Contributors: Kevin Rattigan; Martha-Maria Zarou; Brabcova Z; Bodhayan Prasad; Zerbst D; Daniele Sarnello; Eric Kalkman; Angela Ianniciello; Mary Scott; Dunn K et al.
Source: Self-asserted source
Johan Vande Voorde

Cyclocreatine Suppresses Creatine Metabolism and Impairs Prostate Cancer Progression

Cancer research
2022 | Journal article
Part of ISSN: 0008-5472
Contributors: Patel, Rachana; Ford, Catriona A; Rodgers, Lisa; Rushworth, Linda K; Fleming, Janis; Mui, Ernest; Zhang, Tong; Watson, David; Lynch, Victoria; Mackay, Gillian et al.
Source: Self-asserted source
Johan Vande Voorde

The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer

Nature genetics
2021 | Journal article
Part of ISSN: 1061-4036
Contributors: Najumudeen, Arafath K; Ceteci, Fatih; Fey, Sigrid K; Hamm, Gregory; Steven, Rory T; Hall, Holly; Nikula, Chelsea J; Dexter, Alex; Murta, Teresa; Race, Alan M et al.
Source: Self-asserted source
Johan Vande Voorde

The pathogenesis of mesothelioma is driven by a dysregulated translatome

Nature communications
2021 | Journal article
Part of ISSN: 2041-1723
Contributors: Grosso, Stefano; Marini, Alberto; Gyuraszova, Katarina; Voorde, Johan Vande; Sfakianos, Aristeidis; Garland, Gavin D; Tenor, Angela Rubio; Mordue, Ryan; Chernova, Tanya; Morone, Nobu et al.
Source: Self-asserted source
Johan Vande Voorde

MYC regulates fatty acid metabolism through a multigenic program in claudin-low triple negative breast cancer

British journal of cancer
2020 | Journal article
Part of ISSN: 0007-0920
Contributors: Casciano, Jessica C; Perry, Caroline; Cohen-Nowak, Adam J; Miller, Katelyn D; Vande Voorde, Johan; Zhang, Qifeng; Chalmers, Susan; Sandison, Mairi E; Liu, Qin; Hedley, Ann et al.
Source: Self-asserted source
Johan Vande Voorde

Improving the metabolic fidelity of cancer models with a physiological cell culture medium.

Science advances
2019-01 | Journal article
Contributors: Vande Voorde J; Ackermann T; Pfetzer N; Sumpton D; Mackay G; Kalna G; Nixon C; Blyth K; Gottlieb E; Tardito S
Source: Self-asserted source
Johan Vande Voorde via Europe PubMed Central

Increased formate overflow is a hallmark of oxidative cancer

Nature communications
2018 | Journal article
Source: Self-asserted source
Johan Vande Voorde

Acetate Recapturing by Nuclear Acetyl-CoA Synthetase 2 Prevents Loss of Histone Acetylation during Oxygen and Serum Limitation

Cell reports
2017 | Journal article
Source: Self-asserted source
Johan Vande Voorde

The metabolic fate of acetate in cancer

Nature reviews. Cancer
2016 | Journal article
Source: Self-asserted source
Johan Vande Voorde

The Nurture of Tumors Can Drive Their Metabolic Phenotype

Cell metabolism
2016 | Journal article
Source: Self-asserted source
Johan Vande Voorde

Alpha-carboxy nucleoside phosphonates as universal nucleoside triphosphate mimics

Proceedings of the National Academy of Sciences of the United States of America
2015 | Journal article
Source: Self-asserted source
Johan Vande Voorde

Mycoplasma hyorhinis-encoded cytidine deaminase efficiently inactivates cytosine-based anticancer drugs

FEBS Open Bio
2015 | Journal article
Source: Self-asserted source
Johan Vande Voorde

An emerging understanding of the Janus face of the human microbiome: enhancement versus impairment of cancer therapy

The Journal of antimicrobial chemotherapy
2014 | Journal article
Source: Self-asserted source
Johan Vande Voorde

Microwave-assisted synthesis of C-8 aryl and heteroaryl inosines and determination of their inhibitory activities against Plasmodium falciparum purine nucleoside phosphorylase

European journal of medicinal chemistry
2014 | Journal article
Source: Self-asserted source
Johan Vande Voorde

Mycoplasmas and cancer: focus on nucleoside metabolism

EXCLI Journal
2014 | Journal article
Source: Self-asserted source
Johan Vande Voorde

Nucleoside-catabolizing enzymes in mycoplasma-infected tumor cell cultures compromise the cytostatic activity of the anticancer drug gemcitabine

The Journal of biological chemistry
2014 | Journal article
Source: Self-asserted source
Johan Vande Voorde

Mycoplasmas and cancer: focus on nucleoside metabolism.

EXCLI Journal
2014-03 | Journal article
Contributors: Vande Voorde J; Balzarini J; Liekens S
Source: Self-asserted source
Johan Vande Voorde via Europe PubMed Central

Mycoplasma hyorhinis-encoded purine nucleoside phosphorylase: kinetic properties and its effect on the cytostatic potential of purine-based anticancer drugs

Molecular pharmacology
2013 | Journal article
Source: Self-asserted source
Johan Vande Voorde

Role of human hypoxanthine guanine phosphoribosyltransferase in activation of the antiviral agent T-705 (favipiravir)

Molecular pharmacology
2013 | Journal article
Source: Self-asserted source
Johan Vande Voorde

Characterization of pyrimidine nucleoside phosphorylase of Mycoplasma hyorhinis: implications for the clinical efficacy of nucleoside analogues

The Biochemical journal
2012 | Journal article
Source: Self-asserted source
Johan Vande Voorde

Inhibition of pyrimidine and purine nucleoside phosphorylases by a 3,5-dichlorobenzoyl-substituted 2-deoxy-D-ribose-1-phosphate derivative

Biochemical pharmacology
2012 | Journal article
Source: Self-asserted source
Johan Vande Voorde

Phosphoramidate ProTides of the anticancer agent FUDR successfully deliver the preformed bioactive monophosphate in cells and confer advantage over the parent nucleoside

Journal of medicinal chemistry
2011 | Journal article
Source: Self-asserted source
Johan Vande Voorde

Synthesis and biological evaluation of unsaturated keto and exomethylene D-arabinopyranonucleoside analogs: novel 5-fluorouracil analogs that target thymidylate synthase

European journal of medicinal chemistry
2011 | Journal article
Source: Self-asserted source
Johan Vande Voorde

The cytostatic activity of NUC-3073, a phosphoramidate prodrug of 5-fluoro-2'-deoxyuridine, is independent of activation by thymidine kinase and insensitive to degradation by phosphorolytic enzymes

Biochemical pharmacology
2011 | Journal article
Source: Self-asserted source
Johan Vande Voorde

Evidence for the presence of Legionella bacteriophages in environmental water samples

Microbial ecology
2008 | Journal article
Source: Self-asserted source
Johan Vande Voorde