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The University of Oklahoma: Norman, OK, US

2019-11-01 to present | Research Assistant Professor (Chemistry and Biochemistry)

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Jitender Mehla

Virginia Commonwealth University: Richmond, VA, US

2013-09-25 to 2018-06-25 | Postdoctoral fellow (Center for study of biological complexity,)

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Jitender Mehla

National Dairy Research Institute: Karnal, HR, IN

2006-08-01 to 2010-07-01 | Ph.D (Biochemistry)

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Jitender Mehla

Predicting permeation of compounds across the outer membrane of P. aeruginosa using molecular descriptors

Communications Chemistry

2024-04-12 | Journal article

DOI: 10.1038/s42004-024-01161-y

Contributors: Pedro D. Manrique; Inga V. Leus; César A. López; Jitender Mehla; Giuliano Malloci; Silvia Gervasoni; Attilio V. Vargiu; Rama K. Kinthada; Liam Herndon; Nicolas W. Hengartner et al.

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Molecular determinants of avoidance and inhibition of Pseudomonas aeruginosa MexB efflux pump

mBio

2023-07-26 | Journal article

DOI: 10.1128/mbio.01403-23

Contributors: Silvia Gervasoni; Jitender Mehla; Charles R. Bergen; Inga V. Leus; Enrico Margiotta; Giuliano Malloci; Andrea Bosin; Attilio V. Vargiu; Olga Lomovskaya; Valentin V. Rybenkov et al.

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Proton transfer activity of the reconstituted Mycobacterium tuberculosis MmpL3 is modulated by substrate mimics and inhibitors

Proceedings of the National Academy of Sciences

2022-07-26 | Journal article

DOI: 10.1073/pnas.2113963119

Contributors: Casey M. Stevens; Svitlana O. Babii; Amitkumar N. Pandya; Wei Li; Yupeng Li; Jitender Mehla; Robyn Scott; Pooja Hegde; Pavan K. Prathipati; Atanu Acharya et al.

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ZapG (YhcB/DUF1043), a novel cell division protein in gamma-proteobacteria linking the Z-ring to septal peptidoglycan synthesis

Journal of Biological Chemistry

2021-01 | Journal article

DOI: 10.1016/j.jbc.2021.100700

Contributors: Jitender Mehla; George Liechti; Randy M. Morgenstein; J. Harry Caufield; Ali Hosseinnia; Alla Gagarinova; Sadhna Phanse; Norman Goodacre; Mary Brockett; Neha Sakhawalkar et al.

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YhcB (DUF1043), a novel cell division protein conserved across gamma-proteobacteria

2021-01-02 | Other

DOI: 10.1101/2020.12.31.425005

Contributors: Jitender Mehla; George Liechti; Randy M. Morgenstein; J. Harry Caufield; Ali Hosseinnia; Alla Gagarinova; Sadhna Phanse; Mary Brockett; Neha Sakhawalkar; Mohan Babu et al.

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Defining new chemical space for drug penetration into Gram-negative bacteria

Nature Chemical Biology

2020-12 | Journal article

DOI: 10.1038/s41589-020-00674-6

Contributors: Shibin Zhao; Justyna W. Adamiak; Vincent Bonifay; Jitender Mehla; Helen I. Zgurskaya; Derek S. Tan

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A Comparison of Two-Hybrid Approaches for Detecting Protein-Protein Interactions.

Methods in enzymology

2017 | Journal article

DOI: 10.1016/bs.mie.2016.10.020

PMID: 28137570

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Jitender Mehla via Europe PubMed Central

Virus-host protein-protein interactions of mycobacteriophage Giles.

2017 | Other

OTHER-ID:

S-EPMC5705681

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EMBL-EBI

Bam35 tectivirus intraviral interaction map unveils new function and localization of phage ORFan proteins.

Journal of virology

2017-07 | Journal article

DOI: 10.1128/jvi.00870-17

PMID: 28747494

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Jitender Mehla via Europe PubMed Central

The phosphocarrier protein HPr of the bacterial phosphotransferase system globally regulates energy metabolism by directly interacting with multiple enzymes in Escherichia coli.

The Journal of biological chemistry

2017-06 | Journal article

DOI: 10.1074/jbc.m117.795294

PMID: 28634232

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Jitender Mehla via Europe PubMed Central

Common Mechanism of Cross-Resistance Development in Pathogenic Bacteria Bacillus cereus Against Alamethicin and Pediocin Involves Alteration in Lipid Composition.

2016-07 | Journal article

PMID: 27378130

Contributors: Meena S; Mehla J; Kumar R; Sood SK

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Jitender Mehla via Europe PubMed Central

The Protein Interactome of Mycobacteriophage Giles Predicts Functions for Unknown Proteins.

2015-08 | Journal article

DOI: 10.1128/JB.00164-15

PMID: 25986902

PMC: PMC4518834

Contributors: Mehla J; Dedrick RM; Caufield JH; Siefring R; Mair M; Johnson A; Hatfull GF; Uetz P

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Jitender Mehla via Europe PubMed Central

Mapping protein-protein interactions using yeast two-hybrid assays.

2015-05 | Journal article

DOI: 10.1101/pdb.prot086157

PMID: 25934935

Contributors: Mehla J; Caufield JH; Uetz P

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Jitender Mehla via Europe PubMed Central

The yeast two-hybrid system: a tool for mapping protein-protein interactions.

2015-05 | Journal article

DOI: 10.1101/pdb.top083345

PMID: 25934943

Contributors: Mehla J; Caufield JH; Uetz P

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Jitender Mehla via Europe PubMed Central

Evidence for a molecular diode-based mechanism in a multispecific ATP-binding cassette (ABC) exporter: SER-1368 as a gatekeeping residue in the yeast multidrug transporter Pdr5.

2014-09 | Journal article

DOI: 10.1074/jbc.M114.586032

PMID: 25112867

PMC: PMC4176199

Contributors: Mehla J; Ernst R; Moore R; Wakschlag A; Marquis MK; Ambudkar SV; Golin J

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Jitender Mehla via Europe PubMed Central

The deviant ATP-binding site of the multidrug efflux pump Pdr5 plays an active role in the transport cycle.

2013-10 | Journal article

DOI: 10.1074/jbc.M113.494682

PMID: 24019526

PMC: PMC3798506

Contributors: Furman C; Mehla J; Ananthaswamy N; Arya N; Kulesh B; Kovach I; Ambudkar SV; Golin J

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Jitender Mehla via Europe PubMed Central

Connecting membrane fluidity and surface charge to pore-forming antimicrobial peptides resistance by an ANN-based predictive model.

2013-05 | Journal article

DOI: 10.1007/s00253-012-4289-4

PMID: 22836781

Contributors: Mehla J; Sood SK

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Jitender Mehla via Europe PubMed Central

Highly Specific Culture-Independent Detection of YGNGV Motif-Containing Pediocin-Producing Strains.

2013-03 | Journal article

DOI: 10.1007/s12602-012-9114-y

PMID: 26782603

Contributors: Sood SK; Vijay Simha B; Kumariya R; Garsa AK; Mehla J; Meena S; Lather P

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Jitender Mehla via Europe PubMed Central

The transmission interface of the Saccharomyces cerevisiae multidrug transporter Pdr5: Val-656 located in intracellular loop 2 plays a major role in drug resistance.

2013-02 | Journal article

DOI: 10.1128/AAC.02133-12

PMID: 23254431

PMC: PMC3553689

Contributors: Downes MT; Mehla J; Ananthaswamy N; Wakschlag A; Lamonde M; Dine E; Ambudkar SV; Golin J

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Jitender Mehla via Europe PubMed Central

Substantiation in Enterococcus faecalis of dose-dependent resistance and cross-resistance to pore-forming antimicrobial peptides by use of a polydiacetylene-based colorimetric assay.

2011-02 | Journal article

DOI: 10.1128/AEM.01496-10

PMID: 21115699

PMC: PMC3028714

Contributors: Mehla J; Sood SK

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Jitender Mehla via Europe PubMed Central

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https://orcid.org/0000-0002-7829-557X

Other IDs

Activities

Employment (2)

The University of Oklahoma: Norman, OK, US

Virginia Commonwealth University: Richmond, VA, US

Education and qualifications (1)

National Dairy Research Institute: Karnal, HR, IN

Works (20)

Predicting permeation of compounds across the outer membrane of P. aeruginosa using molecular descriptors

Molecular determinants of avoidance and inhibition of Pseudomonas aeruginosa MexB efflux pump

Proton transfer activity of the reconstituted Mycobacterium tuberculosis MmpL3 is modulated by substrate mimics and inhibitors

ZapG (YhcB/DUF1043), a novel cell division protein in gamma-proteobacteria linking the Z-ring to septal peptidoglycan synthesis

YhcB (DUF1043), a novel cell division protein conserved across gamma-proteobacteria

Defining new chemical space for drug penetration into Gram-negative bacteria

A Comparison of Two-Hybrid Approaches for Detecting Protein-Protein Interactions.

Virus-host protein-protein interactions of mycobacteriophage Giles.

Bam35 tectivirus intraviral interaction map unveils new function and localization of phage ORFan proteins.

The phosphocarrier protein HPr of the bacterial phosphotransferase system globally regulates energy metabolism by directly interacting with multiple enzymes in Escherichia coli.

Common Mechanism of Cross-Resistance Development in Pathogenic Bacteria Bacillus cereus Against Alamethicin and Pediocin Involves Alteration in Lipid Composition.

The Protein Interactome of Mycobacteriophage Giles Predicts Functions for Unknown Proteins.

Mapping protein-protein interactions using yeast two-hybrid assays.

The yeast two-hybrid system: a tool for mapping protein-protein interactions.

Evidence for a molecular diode-based mechanism in a multispecific ATP-binding cassette (ABC) exporter: SER-1368 as a gatekeeping residue in the yeast multidrug transporter Pdr5.

The deviant ATP-binding site of the multidrug efflux pump Pdr5 plays an active role in the transport cycle.

Connecting membrane fluidity and surface charge to pore-forming antimicrobial peptides resistance by an ANN-based predictive model.

Highly Specific Culture-Independent Detection of YGNGV Motif-Containing Pediocin-Producing Strains.

The transmission interface of the Saccharomyces cerevisiae multidrug transporter Pdr5: Val-656 located in intracellular loop 2 plays a major role in drug resistance.

Substantiation in Enterococcus faecalis of dose-dependent resistance and cross-resistance to pore-forming antimicrobial peptides by use of a polydiacetylene-based colorimetric assay.

https://orcid.org/0000-0002-7829-557X

Personal information

Other IDs

Activities

Employment (2)

The University of Oklahoma: Norman, OK, US

Virginia Commonwealth University: Richmond, VA, US

Education and qualifications (1)

National Dairy Research Institute: Karnal, HR, IN

Works (20)

Predicting permeation of compounds across the outer membrane of P. aeruginosa using molecular descriptors

Molecular determinants of avoidance and inhibition of Pseudomonas aeruginosa MexB efflux pump

Proton transfer activity of the reconstituted Mycobacterium tuberculosis MmpL3 is modulated by substrate mimics and inhibitors

ZapG (YhcB/DUF1043), a novel cell division protein in gamma-proteobacteria linking the Z-ring to septal peptidoglycan synthesis

YhcB (DUF1043), a novel cell division protein conserved across gamma-proteobacteria

Defining new chemical space for drug penetration into Gram-negative bacteria

A Comparison of Two-Hybrid Approaches for Detecting Protein-Protein Interactions.

Virus-host protein-protein interactions of mycobacteriophage Giles.

Bam35 tectivirus intraviral interaction map unveils new function and localization of phage ORFan proteins.

The phosphocarrier protein HPr of the bacterial phosphotransferase system globally regulates energy metabolism by directly interacting with multiple enzymes in Escherichia coli.

Common Mechanism of Cross-Resistance Development in Pathogenic Bacteria Bacillus cereus Against Alamethicin and Pediocin Involves Alteration in Lipid Composition.

The Protein Interactome of Mycobacteriophage Giles Predicts Functions for Unknown Proteins.

Mapping protein-protein interactions using yeast two-hybrid assays.

The yeast two-hybrid system: a tool for mapping protein-protein interactions.

Evidence for a molecular diode-based mechanism in a multispecific ATP-binding cassette (ABC) exporter: SER-1368 as a gatekeeping residue in the yeast multidrug transporter Pdr5.

The deviant ATP-binding site of the multidrug efflux pump Pdr5 plays an active role in the transport cycle.

Connecting membrane fluidity and surface charge to pore-forming antimicrobial peptides resistance by an ANN-based predictive model.

Highly Specific Culture-Independent Detection of YGNGV Motif-Containing Pediocin-Producing Strains.

The transmission interface of the Saccharomyces cerevisiae multidrug transporter Pdr5: Val-656 located in intracellular loop 2 plays a major role in drug resistance.

Substantiation in Enterococcus faecalis of dose-dependent resistance and cross-resistance to pore-forming antimicrobial peptides by use of a polydiacetylene-based colorimetric assay.