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Scopus Author ID: 57171172700

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National Institute of Pharmaceutical Education and Research: Raebareli, Uttar Pradesh, IN

2020-02-20 to present | Associate Professor (Department of Pharmacology and Toxicology)
Employment
Source: Self-asserted source
Rakesh Kumar Singh

Works (28)

Therapeutic potential of chrysin in regulation of interleukin-17 signaling in a repeated intranasal amyloid-beta-induced Alzheimer's disease model

Food & Function
2025 | Journal article
DOI: 10.1039/D4FO05278A
Contributors: Avtar Singh Gautam; Ekta Swarnamayee Panda; Sneha Balki; Shivam Kumar Pandey; Aman Tiwari; Rakesh Kumar Singh
Source: check_circle
Crossref

Intranasal amyloid model of Alzheimer’s disease - potential opportunities and challenges

Pharmacological Reports
2025-01-08 | Journal article
DOI: 10.1007/s43440-024-00692-4
Contributors: Rakesh Kumar Singh
Source: check_circle
Crossref

Quercetin ameliorates neuroinflammatory and neurodegenerative biomarkers in the brain and improves neurobehavioral parameters in a repeated intranasal amyloid-beta exposed model of Alzheimer's disease

Food & Function
2024 | Journal article
DOI: 10.1039/D4FO02602K
Contributors: Vaibhav Uttamrao Lasure; Avtar Singh Gautam; Rakesh Kumar Singh
Source: check_circle
Crossref

Lipids and carotenoids may influence the neuropathology of Alzheimer's disease: A meta-analysis

Archives of Gerontology and Geriatrics Plus
2024-12 | Journal article
DOI: 10.1016/j.aggp.2024.100072
Contributors: Aman Tiwari; Avtar Singh Gautam; Ekta Swarnamayee Panda; Rakesh Kumar Singh
Source: check_circle
Crossref

Protective Effects of NRF2 Activator Sulforaphane in Polyinosinic:Polycytidylic Acid‐Induced In Vitro and In Vivo Model

Journal of Biochemical and Molecular Toxicology
2024-12 | Journal article
DOI: 10.1002/jbt.70086
Contributors: Shailesh Vilas Matsagar; Rakesh Kumar Singh
Source: check_circle
Crossref

MK2 inhibitor PF‐3644022 shows protective effect in mouse microglial N9 cell line induced with cigarette smoke extract

Chemical Biology & Drug Design
2024-07 | Journal article
DOI: 10.1111/cbdd.14592
Contributors: Shikha Asthana; Shivam Kumar Pandey; Avtar Singh Gautam; Rakesh Kumar Singh
Source: check_circle
Crossref

Comparative in silico, in vitro and ex vivo anti‐inflammatory activity of quercetin

MedComm – Future Medicine
2023-06 | Journal article
DOI: 10.1002/mef2.57
Contributors: Shruti S. Choubey; Avtar S. Gautam; Lasure Vaibhav; Shikha Asthana; Anjuman Nanda; Mangaldeep Dey; Rakesh K. Singh
Source: check_circle
Crossref

Roflumilast Protects against Neuroinflammatory Alterations in Brain Tissues of Lipopolysaccharide-induced Mice Model

Current Alzheimer Research
2023-01 | Journal article
DOI: 10.2174/1567205020666230503141817
Contributors: Rakesh Kumar Singh; Nisha Kumari; Shivam Kumar Pandey; Mohammed Zunaid Akhtar; Mangaldeep Dey; Avtar Singh Gautam; Anjuman Nanda; Aman Tiwari
Source: check_circle
Crossref

Exposure of aluminium to C6 glioma cells modulates molecular and functional neurotoxic markers

Journal of Biochemical and Molecular Toxicology
2022-12 | Journal article
DOI: 10.1002/jbt.23210
Contributors: Mangaldeep Dey; Rakesh Kumar Singh
Source: check_circle
Crossref

Iron‐induced cellular in vitro neurotoxic responses in rat C6 cell line

Environmental Toxicology
2022-08 | Journal article
DOI: 10.1002/tox.23543
Contributors: Anuradha Urati; Mangaldeep Dey; Avtar Singh Gautam; Rakesh Kumar Singh
Source: check_circle
Crossref

Neurotoxic effects of aluminium exposure as a potential risk factor for Alzheimer’s disease

Pharmacological Reports
2022-06 | Journal article
DOI: 10.1007/s43440-022-00353-4
Contributors: Mangaldeep Dey; Rakesh Kumar Singh
Source: check_circle
Crossref

Role of toll‐like receptors in modulation of cytokine storm signaling in SARS‐CoV‐2‐induced COVID‐19

Journal of Medical Virology
2022-03 | Journal article
DOI: 10.1002/jmv.27405
Contributors: Moumita Manik; Rakesh K. Singh
Source: check_circle
Crossref

Emerging role of gut microbiota in modulation of neuroinflammation and neurodegeneration with emphasis on Alzheimer's disease

Progress in Neuro-Psychopharmacology and Biological Psychiatry
2021 | Journal article
DOI: 10.1016/j.pnpbp.2020.110112
EID:

2-s2.0-85091239429

Part of ISSN: 18784216 02785846
Contributors: Goyal, D.; Ali, S.A.; Singh, R.K.
Source: Self-asserted source
Rakesh Kumar Singh via Scopus - Elsevier

Inhibition of MK2 kinase as a potential therapeutic target to control neuroinflammation in Alzheimer’s disease

Expert Opinion on Therapeutic Targets
2021 | Journal article
DOI: 10.1080/14728222.2021.1924151
EID:

2-s2.0-85106059423

Part of ISSN: 17447631 14728222
Contributors: Srivastava, S.; Rajopadhye, R.; Dey, M.; Singh, R.K.
Source: Self-asserted source
Rakesh Kumar Singh via Scopus - Elsevier

The clinical correlation of proinflammatory and anti-inflammatory biomarkers with Alzheimer disease: a meta-analysis

Neurological Sciences
2021 | Journal article
DOI: 10.1007/s10072-021-05343-7
EID:

2-s2.0-85106420445

Part of ISSN: 15903478 15901874
Contributors: Anuradha, U.; Kumar, A.; Singh, R.K.
Source: Self-asserted source
Rakesh Kumar Singh via Scopus - Elsevier
grade
Preferred source (of 2)‎

Antagonism of cysteinyl leukotrienes and their receptors as a neuroinflammatory target in Alzheimer’s disease

Neurological Sciences
2020 | Journal article
DOI: 10.1007/s10072-020-04369-7
EID:

2-s2.0-85083806565

Part of ISSN: 15903478 15901874
Contributors: Singh, R.K.
Source: Self-asserted source
Rakesh Kumar Singh via Scopus - Elsevier

Identification of novel Urotensin-II receptor antagonists with potent inhibition of U-II induced pressor response in mice

European Journal of Pharmacology
2020 | Journal article
DOI: 10.1016/j.ejphar.2020.173391
EID:

2-s2.0-85089564804

Part of ISSN: 18790712 00142999
Contributors: Tandon, R.; Soni, A.; Singh, R.K.; Sodhi, R.; Seth, M.K.; Sinha, S.; Sahdev, S.; Dhage, G.; Das, B.; Dastidar, S.G. et al.
Source: Self-asserted source
Rakesh Kumar Singh via Scopus - Elsevier

Recent trends in the management of alzheimer’s disease: Current therapeutic options and drug repurposing approaches

Current Neuropharmacology
2020 | Journal article
DOI: 10.2174/1570159X18666200128121920
EID:

2-s2.0-85090205127

Part of ISSN: 18756190 1570159X
Contributors: Singh, R.K.
Source: Self-asserted source
Rakesh Kumar Singh via Scopus - Elsevier

A novel therapeutic potential of cysteinyl leukotrienes and their receptors modulation in the neurological complications associated with Alzheimer's disease

European Journal of Pharmacology
2019 | Journal article
DOI: 10.1016/j.ejphar.2018.10.040
EID:

2-s2.0-85056483976
Contributors: Rahman, S.O.; Singh, R.K.; Hussain, S.; Akhtar, M.; Najmi, A.K.
Source: Self-asserted source
Rakesh Kumar Singh via Scopus - Elsevier

Novel therapeutic potential of mitogen-activated protein kinase activated protein kinase 2 (MK2) in chronic airway inflammatory disorders

Current Drug Targets
2019 | Journal article
DOI: 10.2174/1389450119666180816121323
EID:

2-s2.0-85061136958
Contributors: Singh, R.K.; Najmi, A.K.
Source: Self-asserted source
Rakesh Kumar Singh via Scopus - Elsevier

Differential effect of p38 and MK2 kinase inhibitors on the inflammatory and toxicity biomarkers in vitro

Human and Experimental Toxicology
2018 | Journal article
DOI: 10.1177/0960327117715901
EID:

2-s2.0-85044939867
Contributors: Singh, R.K.; Diwan, M.; Dastidar, S.G.; Najmi, A.K.
Source: Self-asserted source
Rakesh Kumar Singh via Scopus - Elsevier

Biological functions and role of mitogen-activated protein kinase activated protein kinase 2 (MK2) in inflammatory diseases

Pharmacological Reports
2017 | Journal article
DOI: 10.1016/j.pharep.2017.03.023
EID:

2-s2.0-85020042116
Contributors: Singh, R.K.; Najmi, A.K.; Dastidar, S.G.
Source: Self-asserted source
Rakesh Kumar Singh via Scopus - Elsevier

A review on leukotrienes and their receptors with reference to asthma

Journal of Asthma
2013 | Journal article
DOI: 10.3109/02770903.2013.823447
EID:

2-s2.0-84885940799
Contributors: Singh, R.K.; Tandon, R.; Dastidar, S.G.; Ray, A.
Source: Self-asserted source
Rakesh Kumar Singh via Scopus - Elsevier

Pharmacodynamic and pharmacokinetic profile of RBx 343E48F0: A novel, long acting muscarinic receptor antagonist

European Journal of Pharmacology
2011 | Journal article
DOI: 10.1016/j.ejphar.2011.02.024
EID:

2-s2.0-79953773310
Contributors: Gupta, S.; Malhotra, S.; Sinha, S.; Singh, S.K.; Singh, R.K.; Krishna, S.; Chhabra, P.; Chaira, T.; Kannayiram, J.; Sharma, P. et al.
Source: Self-asserted source
Rakesh Kumar Singh via Scopus - Elsevier

Cysteinyl leukotrienes and their receptors: Molecular and functional characteristics

Pharmacology
2010 | Journal article
DOI: 10.1159/000312669
EID:

2-s2.0-77952823941
Contributors: Singh, R.K.; Gupta, S.; Dastidar, S.; Ray, A.
Source: Self-asserted source
Rakesh Kumar Singh via Scopus - Elsevier

Functional screening of adrenergic receptors by measuring intracellular calcium using the FlexStation scanning fluorimeter

Biotechnology Journal
2009 | Journal article
DOI: 10.1002/biot.200800205
EID:

2-s2.0-64549095636
Contributors: Nanda, K.; Chatterjee, M.; Gupta, S.; Singh, R.; Tiwar, A.; Gupta, D.; Ray, A.
Source: Self-asserted source
Rakesh Kumar Singh via Scopus - Elsevier

Ratiometric Ca<sup>+2</sup> measurement in human recombinant muscarinic receptor subtypes using the flexstation scanning fluorometer

Journal of Receptors and Signal Transduction
2009 | Journal article
DOI: 10.1080/10799890902802634
EID:

2-s2.0-68949190920
Contributors: Gupta, S.; Singh, R.K.; Nanda, K.; Chatterjee, M.; Sundaram, S.; Gupta, D.; Dastidar, S.; Ray, A.
Source: Self-asserted source
Rakesh Kumar Singh via Scopus - Elsevier

Cysteine cathepsin S as an immunomodulatory target: Present and future trends

Expert Opinion on Therapeutic Targets
2008 | Journal article
DOI: 10.1517/14728222.12.3.291
EID:

2-s2.0-41049107484
Contributors: Gupta, S.; Singh, R.K.; Dastidar, S.; Ray, A.
Source: Self-asserted source
Rakesh Kumar Singh via Scopus - Elsevier

Peer review (15 reviews for 10 publications/grants)

Review activity for Ageing research reviews. (1)
Review activity for Biochimica et biophysica acta. (1)
Review activity for Biomedicine & pharmacotherapy. (1)
Review activity for Brain disorders. (3)
Review activity for Environmental science and pollution research international (2)
Review activity for European journal of pharmacology. (1)
Review activity for International journal of biological macromolecules. (2)
Review activity for Journal of trace elements in medicine and biology. (2)
Review activity for Molecular biology reports. (1)
Review activity for Molecular pharmaceutics. (1)
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